Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | METPATHWAY |
| Enrichment Score (ES) | -0.45871693 |
| Normalized Enrichment Score (NES) | -1.5099839 |
| Nominal p-value | 0.041257367 |
| FDR q-value | 0.27731135 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 11 | 0.331 | 0.1278 | No |
| 2 | SRC | SRC Entrez, Source | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 729 | 0.103 | 0.1139 | No |
| 3 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 2228 | 0.057 | 0.0234 | No |
| 4 | CRKL | CRKL Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 2336 | 0.055 | 0.0366 | No |
| 5 | STAT3 | STAT3 Entrez, Source | signal transducer and activator of transcription 3 (acute-phase response factor) | 2887 | 0.045 | 0.0127 | No |
| 6 | HGF | HGF Entrez, Source | hepatocyte growth factor (hepapoietin A; scatter factor) | 3517 | 0.035 | -0.0209 | No |
| 7 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 3993 | 0.029 | -0.0456 | No |
| 8 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 4172 | 0.026 | -0.0488 | No |
| 9 | RAF1 | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 4811 | 0.018 | -0.0896 | No |
| 10 | JUN | JUN Entrez, Source | jun oncogene | 4841 | 0.018 | -0.0848 | No |
| 11 | PTPN11 | PTPN11 Entrez, Source | protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) | 6041 | 0.004 | -0.1732 | No |
| 12 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 6805 | -0.004 | -0.2291 | No |
| 13 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 6842 | -0.004 | -0.2302 | No |
| 14 | RAP1A | RAP1A Entrez, Source | RAP1A, member of RAS oncogene family | 8262 | -0.018 | -0.3296 | No |
| 15 | MAP2K2 | MAP2K2 Entrez, Source | mitogen-activated protein kinase kinase 2 | 8874 | -0.025 | -0.3659 | No |
| 16 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 9438 | -0.031 | -0.3963 | No |
| 17 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 9624 | -0.033 | -0.3973 | No |
| 18 | PTK2B | PTK2B Entrez, Source | PTK2B protein tyrosine kinase 2 beta | 10442 | -0.043 | -0.4422 | Yes |
| 19 | PTEN | PTEN Entrez, Source | phosphatase and tensin homolog (mutated in multiple advanced cancers 1) | 10560 | -0.044 | -0.4338 | Yes |
| 20 | ELK1 | ELK1 Entrez, Source | ELK1, member of ETS oncogene family | 10736 | -0.047 | -0.4288 | Yes |
| 21 | RAP1B | RAP1B Entrez, Source | RAP1B, member of RAS oncogene family | 10907 | -0.050 | -0.4223 | Yes |
| 22 | CRK | CRK Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian) | 10930 | -0.050 | -0.4045 | Yes |
| 23 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11016 | -0.051 | -0.3910 | Yes |
| 24 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 11353 | -0.058 | -0.3938 | Yes |
| 25 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 11607 | -0.063 | -0.3885 | Yes |
| 26 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12184 | -0.079 | -0.4011 | Yes |
| 27 | PXN | PXN Entrez, Source | paxillin | 12322 | -0.084 | -0.3790 | Yes |
| 28 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 12764 | -0.108 | -0.3702 | Yes |
| 29 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 13148 | -0.161 | -0.3367 | Yes |
| 30 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -0.905 | 0.0000 | Yes |
