Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | MITOCHONDRION_ORGANIZATION_AND_BIOGENESIS |
| Enrichment Score (ES) | -0.5210294 |
| Normalized Enrichment Score (NES) | -1.6903425 |
| Nominal p-value | 0.010351967 |
| FDR q-value | 0.16564707 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BCL2L1 | BCL2L1 Entrez, Source | BCL2-like 1 | 4653 | 0.020 | -0.3290 | No |
| 2 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 4780 | 0.019 | -0.3192 | No |
| 3 | BAK1 | BAK1 Entrez, Source | BCL2-antagonist/killer 1 | 5281 | 0.013 | -0.3436 | No |
| 4 | TIMM17A | TIMM17A Entrez, Source | translocase of inner mitochondrial membrane 17 homolog A (yeast) | 5700 | 0.008 | -0.3669 | No |
| 5 | SLC25A1 | SLC25A1 Entrez, Source | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 5938 | 0.005 | -0.3794 | No |
| 6 | HSP90AA1 | HSP90AA1 Entrez, Source | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 6167 | 0.003 | -0.3937 | No |
| 7 | TSPO | TSPO Entrez, Source | translocator protein (18kDa) | 6559 | -0.002 | -0.4215 | No |
| 8 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 6812 | -0.004 | -0.4365 | No |
| 9 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 6874 | -0.004 | -0.4365 | No |
| 10 | BBC3 | BBC3 Entrez, Source | BCL2 binding component 3 | 7363 | -0.009 | -0.4638 | No |
| 11 | MTX2 | MTX2 Entrez, Source | metaxin 2 | 7566 | -0.011 | -0.4675 | No |
| 12 | BAX | BAX Entrez, Source | BCL2-associated X protein | 7784 | -0.013 | -0.4700 | No |
| 13 | NDUFS4 | NDUFS4 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 8040 | -0.016 | -0.4727 | No |
| 14 | TFAM | TFAM Entrez, Source | transcription factor A, mitochondrial | 8685 | -0.023 | -0.4977 | Yes |
| 15 | OPA1 | OPA1 Entrez, Source | optic atrophy 1 (autosomal dominant) | 8736 | -0.023 | -0.4777 | Yes |
| 16 | SLC25A15 | SLC25A15 Entrez, Source | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | 8751 | -0.023 | -0.4548 | Yes |
| 17 | NDUFS7 | NDUFS7 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 8983 | -0.026 | -0.4455 | Yes |
| 18 | TRNT1 | TRNT1 Entrez, Source | tRNA nucleotidyl transferase, CCA-adding, 1 | 9100 | -0.027 | -0.4265 | Yes |
| 19 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 9542 | -0.032 | -0.4269 | Yes |
| 20 | MTERF | MTERF Entrez, Source | mitochondrial transcription termination factor | 9634 | -0.033 | -0.3996 | Yes |
| 21 | MFN2 | MFN2 Entrez, Source | mitofusin 2 | 9758 | -0.035 | -0.3734 | Yes |
| 22 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 9784 | -0.035 | -0.3395 | Yes |
| 23 | FIS1 | FIS1 Entrez, Source | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 9851 | -0.036 | -0.3078 | Yes |
| 24 | TOMM22 | TOMM22 Entrez, Source | translocase of outer mitochondrial membrane 22 homolog (yeast) | 10227 | -0.040 | -0.2951 | Yes |
| 25 | MRPL12 | MRPL12 Entrez, Source | mitochondrial ribosomal protein L12 | 10545 | -0.044 | -0.2737 | Yes |
| 26 | DNM1L | DNM1L Entrez, Source | dynamin 1-like | 10768 | -0.048 | -0.2416 | Yes |
| 27 | TFB2M | TFB2M Entrez, Source | transcription factor B2, mitochondrial | 10804 | -0.048 | -0.1949 | Yes |
| 28 | TIMM44 | TIMM44 Entrez, Source | translocase of inner mitochondrial membrane 44 homolog (yeast) | 11781 | -0.067 | -0.1995 | Yes |
| 29 | MIPEP | MIPEP Entrez, Source | mitochondrial intermediate peptidase | 11835 | -0.068 | -0.1334 | Yes |
| 30 | BID | BID Entrez, Source | BH3 interacting domain death agonist | 12134 | -0.077 | -0.0767 | Yes |
| 31 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 13152 | -0.163 | 0.0143 | Yes |
