Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | MONOVALENT_INORGANIC_CATION_TRANSPORT |
| Enrichment Score (ES) | 0.45923957 |
| Normalized Enrichment Score (NES) | 1.7597431 |
| Nominal p-value | 0.0038387715 |
| FDR q-value | 0.09918651 |
| FWER p-Value | 0.994 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SCNN1A | SCNN1A Entrez, Source | sodium channel, nonvoltage-gated 1 alpha | 433 | 0.123 | 0.0121 | Yes |
| 2 | ABCC8 | ABCC8 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 | 472 | 0.120 | 0.0529 | Yes |
| 3 | KCNB2 | KCNB2 Entrez, Source | potassium voltage-gated channel, Shab-related subfamily, member 2 | 483 | 0.119 | 0.0954 | Yes |
| 4 | KCNJ4 | KCNJ4 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 4 | 546 | 0.114 | 0.1321 | Yes |
| 5 | NOX1 | NOX1 Entrez, Source | NADPH oxidase 1 | 560 | 0.113 | 0.1723 | Yes |
| 6 | KCNV1 | KCNV1 Entrez, Source | potassium channel, subfamily V, member 1 | 687 | 0.105 | 0.2009 | Yes |
| 7 | SCN2B | SCN2B Entrez, Source | sodium channel, voltage-gated, type II, beta | 689 | 0.105 | 0.2389 | Yes |
| 8 | KCNN3 | KCNN3 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 | 1040 | 0.090 | 0.2452 | Yes |
| 9 | KCNJ6 | KCNJ6 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 6 | 1102 | 0.087 | 0.2723 | Yes |
| 10 | KCNAB1 | KCNAB1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | 1117 | 0.087 | 0.3028 | Yes |
| 11 | SCNN1G | SCNN1G Entrez, Source | sodium channel, nonvoltage-gated 1, gamma | 1742 | 0.069 | 0.2808 | Yes |
| 12 | SCN10A | SCN10A Entrez, Source | sodium channel, voltage-gated, type X, alpha | 1814 | 0.067 | 0.2999 | Yes |
| 13 | SCN4B | SCN4B Entrez, Source | sodium channel, voltage-gated, type IV, beta | 1965 | 0.063 | 0.3116 | Yes |
| 14 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 2132 | 0.059 | 0.3207 | Yes |
| 15 | UCP3 | UCP3 Entrez, Source | uncoupling protein 3 (mitochondrial, proton carrier) | 2284 | 0.056 | 0.3296 | Yes |
| 16 | KCNH3 | KCNH3 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 3 | 2561 | 0.050 | 0.3272 | Yes |
| 17 | KCNH4 | KCNH4 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 4 | 2628 | 0.049 | 0.3401 | Yes |
| 18 | KCNMB1 | KCNMB1 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 1 | 2672 | 0.049 | 0.3546 | Yes |
| 19 | KCNA2 | KCNA2 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 2 | 3251 | 0.039 | 0.3253 | Yes |
| 20 | KCNH2 | KCNH2 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 3257 | 0.039 | 0.3392 | Yes |
| 21 | KCNS1 | KCNS1 Entrez, Source | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 | 3324 | 0.038 | 0.3480 | Yes |
| 22 | KCNK1 | KCNK1 Entrez, Source | potassium channel, subfamily K, member 1 | 3345 | 0.037 | 0.3601 | Yes |
| 23 | KCNN4 | KCNN4 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 | 3482 | 0.035 | 0.3628 | Yes |
| 24 | KCNJ2 | KCNJ2 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 2 | 3503 | 0.035 | 0.3741 | Yes |
| 25 | SLC34A3 | SLC34A3 Entrez, Source | solute carrier family 34 (sodium phosphate), member 3 | 3619 | 0.033 | 0.3776 | Yes |
| 26 | KCNE2 | KCNE2 Entrez, Source | potassium voltage-gated channel, Isk-related family, member 2 | 3669 | 0.033 | 0.3859 | Yes |
| 27 | KCNAB3 | KCNAB3 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, beta member 3 | 3756 | 0.032 | 0.3910 | Yes |
| 28 | SCN5A | SCN5A Entrez, Source | sodium channel, voltage-gated, type V, alpha (long QT syndrome 3) | 3775 | 0.032 | 0.4011 | Yes |
| 29 | KCNC3 | KCNC3 Entrez, Source | potassium voltage-gated channel, Shaw-related subfamily, member 3 | 3788 | 0.031 | 0.4116 | Yes |
| 30 | KCND3 | KCND3 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 3 | 3813 | 0.031 | 0.4210 | Yes |
| 31 | SCN7A | SCN7A Entrez, Source | sodium channel, voltage-gated, type VII, alpha | 3851 | 0.030 | 0.4292 | Yes |
| 32 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 3853 | 0.030 | 0.4402 | Yes |
| 33 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 3892 | 0.030 | 0.4482 | Yes |
| 34 | KCNA5 | KCNA5 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 5 | 3911 | 0.030 | 0.4576 | Yes |
| 35 | KCNMB4 | KCNMB4 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 4 | 4059 | 0.028 | 0.4565 | Yes |
| 36 | KCNQ2 | KCNQ2 Entrez, Source | potassium voltage-gated channel, KQT-like subfamily, member 2 | 4151 | 0.026 | 0.4592 | Yes |
| 37 | TCIRG1 | TCIRG1 Entrez, Source | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 4289 | 0.025 | 0.4580 | No |
| 38 | KCNJ3 | KCNJ3 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 3 | 4792 | 0.019 | 0.4269 | No |
| 39 | KCNH1 | KCNH1 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 1 | 4830 | 0.018 | 0.4307 | No |
| 40 | KCNA3 | KCNA3 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 3 | 4844 | 0.018 | 0.4363 | No |
| 41 | ATP6V0C | ATP6V0C Entrez, Source | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | 4900 | 0.017 | 0.4384 | No |
| 42 | UCP1 | UCP1 Entrez, Source | uncoupling protein 1 (mitochondrial, proton carrier) | 4988 | 0.016 | 0.4377 | No |
| 43 | KCNQ3 | KCNQ3 Entrez, Source | potassium voltage-gated channel, KQT-like subfamily, member 3 | 4990 | 0.016 | 0.4435 | No |
| 44 | KCNS3 | KCNS3 Entrez, Source | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 | 5174 | 0.014 | 0.4349 | No |
| 45 | KCNA4 | KCNA4 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 4 | 5299 | 0.013 | 0.4301 | No |
| 46 | SCN11A | SCN11A Entrez, Source | sodium channel, voltage-gated, type XI, alpha | 5399 | 0.011 | 0.4268 | No |
| 47 | KCNN1 | KCNN1 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 | 5531 | 0.010 | 0.4205 | No |
| 48 | SCN4A | SCN4A Entrez, Source | sodium channel, voltage-gated, type IV, alpha | 5567 | 0.009 | 0.4213 | No |
| 49 | KCNIP2 | KCNIP2 Entrez, Source | Kv channel interacting protein 2 | 5898 | 0.006 | 0.3985 | No |
| 50 | KCNJ15 | KCNJ15 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 15 | 6003 | 0.005 | 0.3923 | No |
| 51 | KCNE1 | KCNE1 Entrez, Source | potassium voltage-gated channel, Isk-related family, member 1 | 6053 | 0.004 | 0.3901 | No |
| 52 | SCN9A | SCN9A Entrez, Source | sodium channel, voltage-gated, type IX, alpha | 6177 | 0.003 | 0.3818 | No |
| 53 | KCNG2 | KCNG2 Entrez, Source | potassium voltage-gated channel, subfamily G, member 2 | 6206 | 0.002 | 0.3805 | No |
| 54 | ATP6V1C1 | ATP6V1C1 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 6343 | 0.001 | 0.3705 | No |
| 55 | KCNJ5 | KCNJ5 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 5 | 6426 | -0.000 | 0.3644 | No |
| 56 | SCN1B | SCN1B Entrez, Source | sodium channel, voltage-gated, type I, beta | 6455 | -0.000 | 0.3624 | No |
| 57 | ATP6V1F | ATP6V1F Entrez, Source | ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F | 6674 | -0.003 | 0.3469 | No |
| 58 | UCP2 | UCP2 Entrez, Source | uncoupling protein 2 (mitochondrial, proton carrier) | 6742 | -0.003 | 0.3431 | No |
| 59 | KCNC1 | KCNC1 Entrez, Source | potassium voltage-gated channel, Shaw-related subfamily, member 1 | 6848 | -0.004 | 0.3367 | No |
| 60 | KCNQ1 | KCNQ1 Entrez, Source | potassium voltage-gated channel, KQT-like subfamily, member 1 | 6895 | -0.005 | 0.3349 | No |
| 61 | ATP6V1E1 | ATP6V1E1 Entrez, Source | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | 7257 | -0.008 | 0.3107 | No |
| 62 | ABCC9 | ABCC9 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | 7637 | -0.012 | 0.2864 | No |
| 63 | KCNJ10 | KCNJ10 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 10 | 7799 | -0.014 | 0.2792 | No |
| 64 | KCNJ1 | KCNJ1 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 1 | 8394 | -0.020 | 0.2416 | No |
| 65 | KCNJ12 | KCNJ12 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 12 | 8416 | -0.020 | 0.2472 | No |
| 66 | KCNJ11 | KCNJ11 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 11 | 8880 | -0.025 | 0.2213 | No |
| 67 | ATP6V0E1 | ATP6V0E1 Entrez, Source | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 8981 | -0.026 | 0.2232 | No |
| 68 | CHP | CHP Entrez, Source | - | 9731 | -0.034 | 0.1793 | No |
| 69 | ATP6AP1 | ATP6AP1 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 1 | 10377 | -0.042 | 0.1458 | No |
| 70 | SLC17A3 | SLC17A3 Entrez, Source | solute carrier family 17 (sodium phosphate), member 3 | 11551 | -0.061 | 0.0798 | No |
| 71 | ATP1A4 | ATP1A4 Entrez, Source | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 11791 | -0.067 | 0.0861 | No |
| 72 | SLC8A1 | SLC8A1 Entrez, Source | solute carrier family 8 (sodium/calcium exchanger), member 1 | 12331 | -0.084 | 0.0762 | No |
