Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | NETPATH_IL_4_PATHWAY_DOWN |
| Enrichment Score (ES) | -0.48284966 |
| Normalized Enrichment Score (NES) | -1.7475449 |
| Nominal p-value | 0.0061601643 |
| FDR q-value | 0.14037003 |
| FWER p-Value | 0.996 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 25 | 0.248 | 0.0593 | No |
| 2 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 491 | 0.118 | 0.0535 | No |
| 3 | ALOX5AP | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 727 | 0.103 | 0.0612 | No |
| 4 | TRPV5 | TRPV5 Entrez, Source | transient receptor potential cation channel, subfamily V, member 5 | 903 | 0.095 | 0.0715 | No |
| 5 | LPL | LPL Entrez, Source | lipoprotein lipase | 1116 | 0.087 | 0.0770 | No |
| 6 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 1431 | 0.077 | 0.0723 | No |
| 7 | CHI3L1 | CHI3L1 Entrez, Source | chitinase 3-like 1 (cartilage glycoprotein-39) | 1635 | 0.072 | 0.0747 | No |
| 8 | MFNG | MFNG Entrez, Source | manic fringe homolog (Drosophila) | 1882 | 0.065 | 0.0723 | No |
| 9 | LTB4R | LTB4R Entrez, Source | leukotriene B4 receptor | 1907 | 0.065 | 0.0864 | No |
| 10 | CHST10 | CHST10 Entrez, Source | carbohydrate sulfotransferase 10 | 2649 | 0.049 | 0.0427 | No |
| 11 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2716 | 0.048 | 0.0495 | No |
| 12 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3035 | 0.043 | 0.0361 | No |
| 13 | TLR4 | TLR4 Entrez, Source | toll-like receptor 4 | 3487 | 0.035 | 0.0109 | No |
| 14 | KLK6 | KLK6 Entrez, Source | kallikrein 6 (neurosin, zyme) | 3663 | 0.033 | 0.0058 | No |
| 15 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 3897 | 0.030 | -0.0044 | No |
| 16 | NDRG4 | NDRG4 Entrez, Source | NDRG family member 4 | 4055 | 0.028 | -0.0094 | No |
| 17 | IL2RA | IL2RA Entrez, Source | interleukin 2 receptor, alpha | 4057 | 0.028 | -0.0026 | No |
| 18 | ITPKB | ITPKB Entrez, Source | inositol 1,4,5-trisphosphate 3-kinase B | 4358 | 0.024 | -0.0193 | No |
| 19 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 4412 | 0.023 | -0.0176 | No |
| 20 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 4731 | 0.019 | -0.0368 | No |
| 21 | GZMA | GZMA Entrez, Source | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 5197 | 0.014 | -0.0684 | No |
| 22 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 5828 | 0.006 | -0.1142 | No |
| 23 | CAV3 | CAV3 Entrez, Source | caveolin 3 | 6031 | 0.004 | -0.1283 | No |
| 24 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 6376 | 0.000 | -0.1541 | No |
| 25 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 6762 | -0.003 | -0.1822 | No |
| 26 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 7101 | -0.007 | -0.2060 | No |
| 27 | KIT | KIT Entrez, Source | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 7251 | -0.008 | -0.2152 | No |
| 28 | CYSLTR2 | CYSLTR2 Entrez, Source | cysteinyl leukotriene receptor 2 | 7476 | -0.010 | -0.2296 | No |
| 29 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 7490 | -0.010 | -0.2280 | No |
| 30 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 7608 | -0.012 | -0.2339 | No |
| 31 | NINJ1 | NINJ1 Entrez, Source | ninjurin 1 | 7747 | -0.013 | -0.2411 | No |
| 32 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 7778 | -0.013 | -0.2400 | No |
| 33 | TLR2 | TLR2 Entrez, Source | toll-like receptor 2 | 8424 | -0.020 | -0.2837 | No |
| 34 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 8457 | -0.020 | -0.2811 | No |
| 35 | KCNN2 | KCNN2 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 | 8839 | -0.024 | -0.3038 | No |
| 36 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 9056 | -0.027 | -0.3134 | No |
| 37 | CLTB | CLTB Entrez, Source | clathrin, light chain (Lcb) | 9694 | -0.034 | -0.3530 | No |
| 38 | UBE2L6 | UBE2L6 Entrez, Source | ubiquitin-conjugating enzyme E2L 6 | 10532 | -0.044 | -0.4051 | No |
| 39 | ALOX5 | ALOX5 Entrez, Source | arachidonate 5-lipoxygenase | 10694 | -0.046 | -0.4059 | No |
| 40 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 11718 | -0.065 | -0.4668 | Yes |
| 41 | CD9 | CD9 Entrez, Source | CD9 molecule | 11802 | -0.067 | -0.4564 | Yes |
| 42 | KLF15 | KLF15 Entrez, Source | Kruppel-like factor 15 | 12038 | -0.074 | -0.4558 | Yes |
| 43 | VIM | VIM Entrez, Source | vimentin | 12125 | -0.077 | -0.4434 | Yes |
| 44 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 12415 | -0.087 | -0.4436 | Yes |
| 45 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 12422 | -0.088 | -0.4224 | Yes |
| 46 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 12964 | -0.127 | -0.4317 | Yes |
| 47 | LGALS2 | LGALS2 Entrez, Source | lectin, galactoside-binding, soluble, 2 (galectin 2) | 13202 | -0.192 | -0.4021 | Yes |
| 48 | LTB | LTB Entrez, Source | lymphotoxin beta (TNF superfamily, member 3) | 13250 | -0.220 | -0.3513 | Yes |
| 49 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13262 | -0.231 | -0.2951 | Yes |
| 50 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 13267 | -0.235 | -0.2375 | Yes |
| 51 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13292 | -0.273 | -0.1720 | Yes |
| 52 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13314 | -0.341 | -0.0896 | Yes |
| 53 | GBP2 | GBP2 Entrez, Source | guanylate binding protein 2, interferon-inducible | 13323 | -0.371 | 0.0014 | Yes |
