Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | NEUROTRANSMITTER_RECEPTOR_ACTIVITY |
| Enrichment Score (ES) | 0.5008856 |
| Normalized Enrichment Score (NES) | 1.7696865 |
| Nominal p-value | 0.008064516 |
| FDR q-value | 0.092031494 |
| FWER p-Value | 0.993 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CHRNA7 | CHRNA7 Entrez, Source | cholinergic receptor, nicotinic, alpha 7 | 107 | 0.175 | 0.0722 | Yes |
| 2 | CCKBR | CCKBR Entrez, Source | cholecystokinin B receptor | 632 | 0.108 | 0.0825 | Yes |
| 3 | MCHR1 | MCHR1 Entrez, Source | melanin-concentrating hormone receptor 1 | 702 | 0.104 | 0.1251 | Yes |
| 4 | GABRG2 | GABRG2 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, gamma 2 | 804 | 0.099 | 0.1632 | Yes |
| 5 | CCKAR | CCKAR Entrez, Source | cholecystokinin A receptor | 899 | 0.095 | 0.2001 | Yes |
| 6 | CHRNA3 | CHRNA3 Entrez, Source | cholinergic receptor, nicotinic, alpha 3 | 992 | 0.092 | 0.2353 | Yes |
| 7 | DRD3 | DRD3 Entrez, Source | dopamine receptor D3 | 1048 | 0.090 | 0.2724 | Yes |
| 8 | GABRA4 | GABRA4 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, alpha 4 | 1177 | 0.085 | 0.3016 | Yes |
| 9 | GALR1 | GALR1 Entrez, Source | galanin receptor 1 | 1495 | 0.075 | 0.3122 | Yes |
| 10 | CHRM5 | CHRM5 Entrez, Source | cholinergic receptor, muscarinic 5 | 1558 | 0.073 | 0.3412 | Yes |
| 11 | CHRM2 | CHRM2 Entrez, Source | cholinergic receptor, muscarinic 2 | 1771 | 0.068 | 0.3565 | Yes |
| 12 | CHRM4 | CHRM4 Entrez, Source | cholinergic receptor, muscarinic 4 | 1851 | 0.066 | 0.3810 | Yes |
| 13 | DRD1 | DRD1 Entrez, Source | dopamine receptor D1 | 2005 | 0.062 | 0.3982 | Yes |
| 14 | SSTR2 | SSTR2 Entrez, Source | somatostatin receptor 2 | 2014 | 0.062 | 0.4261 | Yes |
| 15 | CHRM1 | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 2092 | 0.060 | 0.4480 | Yes |
| 16 | CHRNB2 | CHRNB2 Entrez, Source | cholinergic receptor, nicotinic, beta 2 (neuronal) | 2101 | 0.060 | 0.4750 | Yes |
| 17 | TACR3 | TACR3 Entrez, Source | tachykinin receptor 3 | 2122 | 0.060 | 0.5009 | Yes |
| 18 | GALR3 | GALR3 Entrez, Source | galanin receptor 3 | 3077 | 0.042 | 0.4484 | No |
| 19 | TACR2 | TACR2 Entrez, Source | tachykinin receptor 2 | 3142 | 0.041 | 0.4624 | No |
| 20 | SSTR4 | SSTR4 Entrez, Source | somatostatin receptor 4 | 3223 | 0.040 | 0.4747 | No |
| 21 | CHRNA6 | CHRNA6 Entrez, Source | cholinergic receptor, nicotinic, alpha 6 | 4014 | 0.028 | 0.4282 | No |
| 22 | DRD2 | DRD2 Entrez, Source | dopamine receptor D2 | 4082 | 0.027 | 0.4357 | No |
| 23 | DRD4 | DRD4 Entrez, Source | dopamine receptor D4 | 4220 | 0.026 | 0.4371 | No |
| 24 | CHRNA2 | CHRNA2 Entrez, Source | cholinergic receptor, nicotinic, alpha 2 (neuronal) | 4515 | 0.022 | 0.4250 | No |
| 25 | TACR1 | TACR1 Entrez, Source | tachykinin receptor 1 | 4658 | 0.020 | 0.4235 | No |
| 26 | DRD5 | DRD5 Entrez, Source | dopamine receptor D5 | 4895 | 0.017 | 0.4137 | No |
| 27 | GABRA6 | GABRA6 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, alpha 6 | 5056 | 0.015 | 0.4087 | No |
| 28 | NMUR2 | NMUR2 Entrez, Source | neuromedin U receptor 2 | 5367 | 0.012 | 0.3907 | No |
| 29 | CHRNA4 | CHRNA4 Entrez, Source | cholinergic receptor, nicotinic, alpha 4 | 5906 | 0.005 | 0.3528 | No |
| 30 | NMUR1 | NMUR1 Entrez, Source | neuromedin U receptor 1 | 6304 | 0.001 | 0.3235 | No |
| 31 | GABRA3 | GABRA3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, alpha 3 | 6408 | 0.000 | 0.3159 | No |
| 32 | TSPO | TSPO Entrez, Source | translocator protein (18kDa) | 6559 | -0.002 | 0.3053 | No |
| 33 | CHRNE | CHRNE Entrez, Source | cholinergic receptor, nicotinic, epsilon | 6825 | -0.004 | 0.2872 | No |
| 34 | CHRNB4 | CHRNB4 Entrez, Source | cholinergic receptor, nicotinic, beta 4 | 7214 | -0.008 | 0.2616 | No |
| 35 | CHRNA1 | CHRNA1 Entrez, Source | cholinergic receptor, nicotinic, alpha 1 (muscle) | 7580 | -0.011 | 0.2393 | No |
| 36 | NMBR | NMBR Entrez, Source | neuromedin B receptor | 7890 | -0.014 | 0.2227 | No |
| 37 | KISS1R | KISS1R Entrez, Source | KISS1 receptor | 8190 | -0.018 | 0.2083 | No |
| 38 | HCRTR2 | HCRTR2 Entrez, Source | hypocretin (orexin) receptor 2 | 8532 | -0.021 | 0.1924 | No |
| 39 | GALR2 | GALR2 Entrez, Source | galanin receptor 2 | 9407 | -0.030 | 0.1406 | No |
| 40 | SSTR5 | SSTR5 Entrez, Source | somatostatin receptor 5 | 9703 | -0.034 | 0.1340 | No |
| 41 | CHRM3 | CHRM3 Entrez, Source | cholinergic receptor, muscarinic 3 | 9961 | -0.037 | 0.1316 | No |
| 42 | SSTR1 | SSTR1 Entrez, Source | somatostatin receptor 1 | 10304 | -0.041 | 0.1246 | No |
| 43 | CHRNA5 | CHRNA5 Entrez, Source | cholinergic receptor, nicotinic, alpha 5 | 12619 | -0.098 | -0.0045 | No |
| 44 | CHRNB1 | CHRNB1 Entrez, Source | cholinergic receptor, nicotinic, beta 1 (muscle) | 12969 | -0.128 | 0.0280 | No |
