Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | OXIDOREDUCTASE_ACTIVITY_GO_0016616 |
| Enrichment Score (ES) | 0.5290719 |
| Normalized Enrichment Score (NES) | 1.757606 |
| Nominal p-value | 0.007736944 |
| FDR q-value | 0.09918326 |
| FWER p-Value | 0.995 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 7 | 0.362 | 0.1868 | Yes |
| 2 | BDH1 | BDH1 Entrez, Source | 3-hydroxybutyrate dehydrogenase, type 1 | 121 | 0.169 | 0.2657 | Yes |
| 3 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 214 | 0.147 | 0.3348 | Yes |
| 4 | HSD17B7 | HSD17B7 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 7 | 313 | 0.134 | 0.3967 | Yes |
| 5 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 379 | 0.127 | 0.4578 | Yes |
| 6 | MIOX | MIOX Entrez, Source | myo-inositol oxygenase | 881 | 0.096 | 0.4699 | Yes |
| 7 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 1022 | 0.091 | 0.5063 | Yes |
| 8 | AKR1B10 | AKR1B10 Entrez, Source | aldo-keto reductase family 1, member B10 (aldose reductase) | 1279 | 0.081 | 0.5291 | Yes |
| 9 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 2110 | 0.060 | 0.4977 | No |
| 10 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 3529 | 0.035 | 0.4092 | No |
| 11 | NSDHL | NSDHL Entrez, Source | NAD(P) dependent steroid dehydrogenase-like | 4607 | 0.021 | 0.3389 | No |
| 12 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 5228 | 0.013 | 0.2993 | No |
| 13 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 5527 | 0.010 | 0.2821 | No |
| 14 | DHRS9 | DHRS9 Entrez, Source | dehydrogenase/reductase (SDR family) member 9 | 5622 | 0.009 | 0.2796 | No |
| 15 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 5790 | 0.007 | 0.2706 | No |
| 16 | SPR | SPR Entrez, Source | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 6410 | 0.000 | 0.2241 | No |
| 17 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 6634 | -0.002 | 0.2086 | No |
| 18 | HSD17B4 | HSD17B4 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 4 | 6653 | -0.002 | 0.2085 | No |
| 19 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 7066 | -0.006 | 0.1808 | No |
| 20 | AKR7A2 | AKR7A2 Entrez, Source | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 7115 | -0.007 | 0.1807 | No |
| 21 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 7288 | -0.009 | 0.1722 | No |
| 22 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 7513 | -0.011 | 0.1609 | No |
| 23 | RDH10 | RDH10 Entrez, Source | retinol dehydrogenase 10 (all-trans) | 7839 | -0.014 | 0.1437 | No |
| 24 | LDHC | LDHC Entrez, Source | lactate dehydrogenase C | 7848 | -0.014 | 0.1503 | No |
| 25 | RDH11 | RDH11 Entrez, Source | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 8080 | -0.017 | 0.1415 | No |
| 26 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 8240 | -0.018 | 0.1390 | No |
| 27 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 8609 | -0.022 | 0.1227 | No |
| 28 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 9698 | -0.034 | 0.0585 | No |
| 29 | GPD1 | GPD1 Entrez, Source | glycerol-3-phosphate dehydrogenase 1 (soluble) | 10037 | -0.038 | 0.0526 | No |
| 30 | IDH3G | IDH3G Entrez, Source | isocitrate dehydrogenase 3 (NAD+) gamma | 10481 | -0.043 | 0.0416 | No |
| 31 | IDH3B | IDH3B Entrez, Source | isocitrate dehydrogenase 3 (NAD+) beta | 10868 | -0.049 | 0.0381 | No |
| 32 | CBR1 | CBR1 Entrez, Source | carbonyl reductase 1 | 10998 | -0.051 | 0.0547 | No |
| 33 | AKR7A3 | AKR7A3 Entrez, Source | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 11159 | -0.054 | 0.0707 | No |
| 34 | PHGDH | PHGDH Entrez, Source | phosphoglycerate dehydrogenase | 12426 | -0.088 | 0.0211 | No |
| 35 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 12511 | -0.092 | 0.0624 | No |
