Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | P38MAPKPATHWAY |
| Enrichment Score (ES) | 0.46534193 |
| Normalized Enrichment Score (NES) | 1.4798691 |
| Nominal p-value | 0.043392505 |
| FDR q-value | 0.2798246 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 5 | 0.389 | 0.2349 | Yes |
| 2 | DDIT3 | DDIT3 Entrez, Source | DNA-damage-inducible transcript 3 | 356 | 0.129 | 0.2866 | Yes |
| 3 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 763 | 0.101 | 0.3174 | Yes |
| 4 | HSPB2 | HSPB2 Entrez, Source | heat shock 27kDa protein 2 | 1028 | 0.091 | 0.3523 | Yes |
| 5 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1411 | 0.077 | 0.3704 | Yes |
| 6 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 1493 | 0.075 | 0.4097 | Yes |
| 7 | MEF2D | MEF2D Entrez, Source | MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) | 1595 | 0.073 | 0.4460 | Yes |
| 8 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 2040 | 0.061 | 0.4497 | Yes |
| 9 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 2282 | 0.056 | 0.4653 | Yes |
| 10 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 4288 | 0.025 | 0.3298 | No |
| 11 | ATF2 | ATF2 Entrez, Source | activating transcription factor 2 | 6021 | 0.004 | 0.2024 | No |
| 12 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 6688 | -0.003 | 0.1540 | No |
| 13 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 6805 | -0.004 | 0.1476 | No |
| 14 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 7416 | -0.010 | 0.1077 | No |
| 15 | TGFBR1 | TGFBR1 Entrez, Source | transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) | 7514 | -0.011 | 0.1068 | No |
| 16 | HMGN1 | HMGN1 Entrez, Source | high-mobility group nucleosome binding domain 1 | 7731 | -0.013 | 0.0984 | No |
| 17 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 7778 | -0.013 | 0.1030 | No |
| 18 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 7869 | -0.014 | 0.1049 | No |
| 19 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 8761 | -0.023 | 0.0521 | No |
| 20 | TRADD | TRADD Entrez, Source | TNFRSF1A-associated via death domain | 9040 | -0.026 | 0.0473 | No |
| 21 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 9335 | -0.029 | 0.0430 | No |
| 22 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 9571 | -0.032 | 0.0449 | No |
| 23 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 9624 | -0.033 | 0.0610 | No |
| 24 | MAX | MAX Entrez, Source | MYC associated factor X | 10440 | -0.042 | 0.0255 | No |
| 25 | ELK1 | ELK1 Entrez, Source | ELK1, member of ETS oncogene family | 10736 | -0.047 | 0.0317 | No |
| 26 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 11443 | -0.059 | 0.0146 | No |
| 27 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 11474 | -0.060 | 0.0487 | No |
| 28 | TGFB3 | TGFB3 Entrez, Source | transforming growth factor, beta 3 | 13109 | -0.151 | 0.0175 | No |
