Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | PEPTIDE_GPCRS |
| Enrichment Score (ES) | 0.52096605 |
| Normalized Enrichment Score (NES) | 1.9077722 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.04831875 |
| FWER p-Value | 0.695 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GNRHR | GNRHR Entrez, Source | gonadotropin-releasing hormone receptor | 156 | 0.157 | 0.0366 | Yes |
| 2 | NPY1R | NPY1R Entrez, Source | neuropeptide Y receptor Y1 | 178 | 0.152 | 0.0819 | Yes |
| 3 | IL8RA | IL8RA Entrez, Source | interleukin 8 receptor, alpha | 228 | 0.145 | 0.1227 | Yes |
| 4 | OPRM1 | OPRM1 Entrez, Source | opioid receptor, mu 1 | 297 | 0.136 | 0.1593 | Yes |
| 5 | LHCGR | LHCGR Entrez, Source | luteinizing hormone/choriogonadotropin receptor | 330 | 0.132 | 0.1975 | Yes |
| 6 | CCKBR | CCKBR Entrez, Source | cholecystokinin B receptor | 632 | 0.108 | 0.2081 | Yes |
| 7 | TRHR | TRHR Entrez, Source | thyrotropin-releasing hormone receptor | 639 | 0.108 | 0.2408 | Yes |
| 8 | CXCR3 | CXCR3 Entrez, Source | chemokine (C-X-C motif) receptor 3 | 648 | 0.107 | 0.2732 | Yes |
| 9 | CX3CR1 | CX3CR1 Entrez, Source | chemokine (C-X3-C motif) receptor 1 | 768 | 0.101 | 0.2953 | Yes |
| 10 | CCKAR | CCKAR Entrez, Source | cholecystokinin A receptor | 899 | 0.095 | 0.3149 | Yes |
| 11 | PPYR1 | PPYR1 Entrez, Source | pancreatic polypeptide receptor 1 | 1111 | 0.087 | 0.3257 | Yes |
| 12 | OPRK1 | OPRK1 Entrez, Source | opioid receptor, kappa 1 | 1142 | 0.086 | 0.3499 | Yes |
| 13 | IL8RB | IL8RB Entrez, Source | interleukin 8 receptor, beta | 1170 | 0.085 | 0.3740 | Yes |
| 14 | CCR3 | CCR3 Entrez, Source | chemokine (C-C motif) receptor 3 | 1227 | 0.083 | 0.3952 | Yes |
| 15 | OPRD1 | OPRD1 Entrez, Source | opioid receptor, delta 1 | 1267 | 0.081 | 0.4173 | Yes |
| 16 | GALR1 | GALR1 Entrez, Source | galanin receptor 1 | 1495 | 0.075 | 0.4232 | Yes |
| 17 | CCR6 | CCR6 Entrez, Source | chemokine (C-C motif) receptor 6 | 1581 | 0.073 | 0.4392 | Yes |
| 18 | GRPR | GRPR Entrez, Source | gastrin-releasing peptide receptor | 1848 | 0.066 | 0.4396 | Yes |
| 19 | AVPR1B | AVPR1B Entrez, Source | arginine vasopressin receptor 1B | 1870 | 0.066 | 0.4582 | Yes |
| 20 | SSTR2 | SSTR2 Entrez, Source | somatostatin receptor 2 | 2014 | 0.062 | 0.4666 | Yes |
| 21 | AGTR1 | AGTR1 Entrez, Source | angiotensin II receptor, type 1 | 2090 | 0.060 | 0.4795 | Yes |
| 22 | TACR3 | TACR3 Entrez, Source | tachykinin receptor 3 | 2122 | 0.060 | 0.4955 | Yes |
| 23 | OXTR | OXTR Entrez, Source | oxytocin receptor | 2184 | 0.058 | 0.5087 | Yes |
| 24 | EDNRB | EDNRB Entrez, Source | endothelin receptor type B | 2252 | 0.056 | 0.5210 | Yes |
| 25 | AGTR2 | AGTR2 Entrez, Source | angiotensin II receptor, type 2 | 2519 | 0.051 | 0.5167 | No |
| 26 | GALR3 | GALR3 Entrez, Source | galanin receptor 3 | 3077 | 0.042 | 0.4877 | No |
| 27 | TACR2 | TACR2 Entrez, Source | tachykinin receptor 2 | 3142 | 0.041 | 0.4955 | No |
| 28 | SSTR4 | SSTR4 Entrez, Source | somatostatin receptor 4 | 3223 | 0.040 | 0.5017 | No |
| 29 | BLR1 | BLR1 Entrez, Source | Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) | 4045 | 0.028 | 0.4484 | No |
| 30 | CCR5 | CCR5 Entrez, Source | chemokine (C-C motif) receptor 5 | 4484 | 0.022 | 0.4223 | No |
| 31 | AVPR2 | AVPR2 Entrez, Source | arginine vasopressin receptor 2 (nephrogenic diabetes insipidus) | 4489 | 0.022 | 0.4288 | No |
| 32 | C3AR1 | C3AR1 Entrez, Source | complement component 3a receptor 1 | 4527 | 0.021 | 0.4326 | No |
| 33 | TACR1 | TACR1 Entrez, Source | tachykinin receptor 1 | 4658 | 0.020 | 0.4290 | No |
| 34 | GALT | GALT Entrez, Source | galactose-1-phosphate uridylyltransferase | 4837 | 0.018 | 0.4212 | No |
| 35 | NPY5R | NPY5R Entrez, Source | neuropeptide Y receptor Y5 | 5231 | 0.013 | 0.3957 | No |
| 36 | CCR2 | CCR2 Entrez, Source | chemokine (C-C motif) receptor 2 | 5326 | 0.012 | 0.3924 | No |
| 37 | EDNRA | EDNRA Entrez, Source | endothelin receptor type A | 5660 | 0.008 | 0.3699 | No |
| 38 | BDKRB1 | BDKRB1 Entrez, Source | bradykinin receptor B1 | 5701 | 0.008 | 0.3693 | No |
| 39 | TSHR | TSHR Entrez, Source | thyroid stimulating hormone receptor | 5969 | 0.005 | 0.3508 | No |
| 40 | MC5R | MC5R Entrez, Source | melanocortin 5 receptor | 6584 | -0.002 | 0.3051 | No |
| 41 | BDKRB2 | BDKRB2 Entrez, Source | bradykinin receptor B2 | 7014 | -0.006 | 0.2746 | No |
| 42 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 7175 | -0.007 | 0.2648 | No |
| 43 | NMBR | NMBR Entrez, Source | neuromedin B receptor | 7890 | -0.014 | 0.2155 | No |
| 44 | GHSR | GHSR Entrez, Source | growth hormone secretagogue receptor | 8118 | -0.017 | 0.2036 | No |
| 45 | NPY2R | NPY2R Entrez, Source | neuropeptide Y receptor Y2 | 8693 | -0.023 | 0.1674 | No |
| 46 | GALR2 | GALR2 Entrez, Source | galanin receptor 2 | 9407 | -0.030 | 0.1231 | No |
| 47 | OPRL1 | OPRL1 Entrez, Source | opiate receptor-like 1 | 9711 | -0.034 | 0.1108 | No |
| 48 | SSTR1 | SSTR1 Entrez, Source | somatostatin receptor 1 | 10304 | -0.041 | 0.0788 | No |
| 49 | CCR1 | CCR1 Entrez, Source | chemokine (C-C motif) receptor 1 | 10676 | -0.046 | 0.0650 | No |
| 50 | NTSR2 | NTSR2 Entrez, Source | neurotensin receptor 2 | 10880 | -0.049 | 0.0649 | No |
| 51 | MC4R | MC4R Entrez, Source | melanocortin 4 receptor | 11608 | -0.063 | 0.0295 | No |
| 52 | CCR4 | CCR4 Entrez, Source | chemokine (C-C motif) receptor 4 | 11726 | -0.065 | 0.0408 | No |
| 53 | AVPR1A | AVPR1A Entrez, Source | arginine vasopressin receptor 1A | 13282 | -0.262 | 0.0045 | No |
