Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_24h_versus_single_gel_24h.class.cls
#double_gel_24h_versus_single_gel_24h_repos
Phenotypeclass.cls#double_gel_24h_versus_single_gel_24h_repos
Upregulated in classsingle_gel_24h
GeneSetPOD1_KO_DN
Enrichment Score (ES)-0.33447465
Normalized Enrichment Score (NES)-1.5965724
Nominal p-value0.0
FDR q-value0.2401164
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: POD1_KO_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1LYZLYZ
Entrez,  Source
lysozyme (renal amyloidosis)340.2300.0087No
2TCP11L2TCP11L2
Entrez,  Source
t-complex 11 (mouse) like 2460.2140.0184No
3TXNIPTXNIP
Entrez,  Source
thioredoxin interacting protein820.1860.0248No
4EBF1EBF1
Entrez,  Source
early B-cell factor 1980.1790.0325No
5CREBBPCREBBP
Entrez,  Source
CREB binding protein (Rubinstein-Taybi syndrome)1790.1520.0339No
6SPEGSPEG
Entrez,  Source
SPEG complex locus2420.1420.0361No
7IFRD1IFRD1
Entrez,  Source
interferon-related developmental regulator 12630.1400.0414No
8MARK1MARK1
Entrez,  Source
MAP/microtubule affinity-regulating kinase 13230.1320.0434No
9LPHN3LPHN3
Entrez,  Source
latrophilin 33480.1300.0480No
10NID2NID2
Entrez,  Source
nidogen 2 (osteonidogen)3770.1280.0521No
11EGFEGF
Entrez,  Source
epidermal growth factor (beta-urogastrone)3920.1260.0572No
12CTSSCTSS
Entrez,  Source
cathepsin S4620.1200.0579No
13IRS1IRS1
Entrez,  Source
insulin receptor substrate 15490.1140.0568No
14SLKSLK
Entrez,  Source
STE20-like kinase (yeast)5650.1120.0612No
15RAPGEF3RAPGEF3
Entrez,  Source
Rap guanine nucleotide exchange factor (GEF) 35910.1110.0648No
16CLEC14ACLEC14A
Entrez,  Source
C-type lectin domain family 14, member A6900.1050.0624No
17GIMAP4GIMAP4
Entrez,  Source
GTPase, IMAP family member 47720.1010.0611No
18GPC1GPC1
Entrez,  Source
glypican 19760.0920.0500No
19SLC12A2SLC12A2
Entrez,  Source
solute carrier family 12 (sodium/potassium/chloride transporters), member 211140.0870.0437No
20PCOLCEPCOLCE
Entrez,  Source
procollagen C-endopeptidase enhancer11180.0870.0478No
21GABRA4GABRA4
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, alpha 411770.0850.0475No
22PDE10APDE10A
Entrez,  Source
phosphodiesterase 10A12740.0810.0441No
23CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)12870.0810.0471No
24CEBPBCEBPB
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), beta13040.0800.0499No
25LRRC33LRRC33
Entrez,  Source
leucine rich repeat containing 3313330.0790.0516No
26CENTB2CENTB2
Entrez,  Source
centaurin, beta 213350.0790.0554No
27ELTD1ELTD1
Entrez,  Source
EGF, latrophilin and seven transmembrane domain containing 113390.0790.0591No
28TMBIM1TMBIM1
Entrez,  Source
transmembrane BAX inhibitor motif containing 113800.0780.0599No
29EPHB1EPHB1
Entrez,  Source
EPH receptor B113870.0780.0632No
30GPSM3GPSM3
Entrez,  Source
G-protein signalling modulator 3 (AGS3-like, C. elegans)14370.0770.0632No
31GAB2GAB2
Entrez,  Source
GRB2-associated binding protein 214770.0750.0639No
32EPAS1EPAS1
Entrez,  Source
endothelial PAS domain protein 115070.0740.0654No
33SDPRSDPR
Entrez,  Source
serum deprivation response (phosphatidylserine binding protein)15450.0740.0661No
34PRKCHPRKCH
Entrez,  Source
protein kinase C, eta15570.0730.0689No
35FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)15590.0730.0724No
36COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 415610.0730.0760No
37MAGI2MAGI2
Entrez,  Source
membrane associated guanylate kinase, WW and PDZ domain containing 215630.0730.0795No
38GIMAP1GIMAP1
Entrez,  Source
GTPase, IMAP family member 115910.0730.0810No
39MPP3MPP3
Entrez,  Source
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)16010.0720.0839No
40SERPINI1SERPINI1
Entrez,  Source
serpin peptidase inhibitor, clade I (neuroserpin), member 116150.0720.0864No
41PTPROPTPRO
Entrez,  Source
protein tyrosine phosphatase, receptor type, O17580.0680.0789No
42DDNDDN
Entrez,  Source
dendrin18030.0670.0788No
43EHD3EHD3
Entrez,  Source
EH-domain containing 318280.0670.0802No
44TGFBR3TGFBR3
Entrez,  Source
transforming growth factor, beta receptor III (betaglycan, 300kDa)18350.0670.0831No
45YPEL5YPEL5
Entrez,  Source
yippee-like 5 (Drosophila)18420.0660.0859No
46SEC11L3SEC11L3
Entrez,  Source
SEC11-like 3 (S. cerevisiae)19000.0650.0847No
47ATP2A3ATP2A3
Entrez,  Source
ATPase, Ca++ transporting, ubiquitous19120.0640.0870No
48GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha19330.0640.0886No
49SYCP3SYCP3
Entrez,  Source
synaptonemal complex protein 319380.0640.0914No
50CUGBP2CUGBP2
Entrez,  Source
CUG triplet repeat, RNA binding protein 219690.0630.0923No
51RIPK5RIPK5
Entrez,  Source
receptor interacting protein kinase 520190.0620.0915No
52METRNLMETRNL
Entrez,  Source
meteorin, glial cell differentiation regulator-like20770.0610.0901No
53AGTR1AGTR1
Entrez,  Source
angiotensin II receptor, type 120900.0600.0922No
54ODZ2ODZ2
Entrez,  Source
odz, odd Oz/ten-m homolog 2 (Drosophila)21160.0600.0932No
55WDR22WDR22
Entrez,  Source
WD repeat domain 2221230.0590.0957No
56SH2B3SH2B3
Entrez,  Source
SH2B adaptor protein 321460.0590.0969No
57LIFRLIFR
Entrez,  Source
leukemia inhibitory factor receptor alpha21790.0580.0973No
58ADMADM
Entrez,  Source
adrenomedullin21890.0580.0994No
59GJA3GJA3
Entrez,  Source
gap junction protein, alpha 3, 46kDa (connexin 46)22060.0570.1010No
60SYNPOSYNPO
Entrez,  Source
synaptopodin22170.0570.1031No
61ICAM2ICAM2
Entrez,  Source
intercellular adhesion molecule 222460.0560.1037No
62EDNRBEDNRB
Entrez,  Source
endothelin receptor type B22520.0560.1061No
63NOTCH4NOTCH4
Entrez,  Source
Notch homolog 4 (Drosophila)22600.0560.1083No
64SLC9A3R2SLC9A3R2
Entrez,  Source
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 223120.0550.1071No
65LYSMD3LYSMD3
Entrez,  Source
LysM, putative peptidoglycan-binding, domain containing 323550.0540.1065No
66LMO2LMO2
Entrez,  Source
LIM domain only 2 (rhombotin-like 1)23640.0540.1086No
67ACOX1ACOX1
Entrez,  Source
acyl-Coenzyme A oxidase 1, palmitoyl23710.0540.1108No
68ABI3ABI3
Entrez,  Source
ABI gene family, member 325840.0500.0970No
69MGAT5MGAT5
Entrez,  Source
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase28030.0460.0825No
70ITGA9ITGA9
Entrez,  Source
integrin, alpha 928080.0460.0844No
71PDE2APDE2A
Entrez,  Source
phosphodiesterase 2A, cGMP-stimulated28460.0450.0838No
72GALNT10GALNT10
Entrez,  Source
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)28540.0450.0855No
73CALCRLCALCRL
Entrez,  Source
calcitonin receptor-like28680.0450.0867No
74EMCNEMCN
Entrez,  Source
endomucin28820.0450.0879No
75PARVAPARVA
Entrez,  Source
parvin, alpha28850.0450.0900No
76PAMCIPAMCI
Entrez,  Source
peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor29040.0450.0908No
77CXCR7CXCR7
Entrez,  Source
chemokine (C-X-C motif) receptor 729670.0440.0882No
78ATP7AATP7A
Entrez,  Source
ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome)29700.0430.0901No
79DNAJB6DNAJB6
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 629730.0430.0921No
80GIMAP6GIMAP6
Entrez,  Source
GTPase, IMAP family member 629780.0430.0939No
81SLC12A1SLC12A1
Entrez,  Source
solute carrier family 12 (sodium/potassium/chloride transporters), member 129830.0430.0958No
82PFKFB3PFKFB3
Entrez,  Source
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 332850.0390.0745No
83GMDSGMDS
Entrez,  Source
GDP-mannose 4,6-dehydratase34210.0360.0659No
84GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)34750.0360.0636No
85TLR4TLR4
Entrez,  Source
toll-like receptor 434870.0350.0645No
86ATP10AATP10A
Entrez,  Source
ATPase, Class V, type 10A35570.0340.0609No
87COLEC12COLEC12
Entrez,  Source
collectin sub-family member 1236010.0340.0592No
88SEMA3GSEMA3G
Entrez,  Source
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G36210.0330.0594No
89NFIL3NFIL3
Entrez,  Source
nuclear factor, interleukin 3 regulated36610.0330.0580No
90DUSP6DUSP6
Entrez,  Source
dual specificity phosphatase 636990.0330.0568No
91SLC33A1SLC33A1
Entrez,  Source
solute carrier family 33 (acetyl-CoA transporter), member 138120.0310.0497No
92SCN7ASCN7A
Entrez,  Source
sodium channel, voltage-gated, type VII, alpha38510.0300.0483No
93PTPRCPTPRC
Entrez,  Source
protein tyrosine phosphatase, receptor type, C39400.0290.0429No
94BACE1BACE1
Entrez,  Source
beta-site APP-cleaving enzyme 139840.0290.0410No
95ARHGAP5ARHGAP5
Entrez,  Source
Rho GTPase activating protein 540480.0280.0376No
96PTPN12PTPN12
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 1240860.0270.0361No
97GPD2GPD2
Entrez,  Source
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)40910.0270.0371No
98SNRKSNRK
Entrez,  Source
SNF related kinase41090.0270.0371No
99CORO1ACORO1A
Entrez,  Source
coronin, actin binding protein, 1A41240.0270.0373No
100TBX3TBX3
Entrez,  Source
T-box 3 (ulnar mammary syndrome)41340.0270.0380No
101NESNES
Entrez,  Source
nestin41650.0260.0369No
102RFKRFK
Entrez,  Source
riboflavin kinase42940.0250.0283No
103SGPP1SGPP1
Entrez,  Source
sphingosine-1-phosphate phosphatase 143220.0240.0274No
104CTTNBP2CTTNBP2
Entrez,  Source
cortactin binding protein 243450.0240.0269No
105ITPKBITPKB
Entrez,  Source
inositol 1,4,5-trisphosphate 3-kinase B43580.0240.0272No
106E2F5E2F5
Entrez,  Source
E2F transcription factor 5, p130-binding43710.0240.0274No
107ANKRD15ANKRD15
Entrez,  Source
ankyrin repeat domain 1543890.0230.0272No
108PTPRVPTPRV
Entrez,  Source
protein tyrosine phosphatase, receptor type, V (pseudogene)44030.0230.0274No
109VEGFVEGF
Entrez,  Source
vascular endothelial growth factor44070.0230.0283No
110CBLBCBLB
Entrez,  Source
Cas-Br-M (murine) ecotropic retroviral transforming sequence b45500.0210.0184No
111SDC2SDC2
Entrez,  Source
syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan)45690.0210.0181No
112TSPAN8TSPAN8
Entrez,  Source
tetraspanin 845780.0210.0185No
113ITSN1ITSN1
Entrez,  Source
intersectin 1 (SH3 domain protein)45840.0210.0191No
114TEX2TEX2
Entrez,  Source
testis expressed sequence 246260.0200.0170No
115SACM1LSACM1L
Entrez,  Source
SAC1 suppressor of actin mutations 1-like (yeast)46840.0200.0136No
116DLC1DLC1
Entrez,  Source
deleted in liver cancer 148240.0180.0038No
117AK1AK1
Entrez,  Source
adenylate kinase 148320.0180.0041No
118GULP1GULP1
Entrez,  Source
GULP, engulfment adaptor PTB domain containing 148450.0180.0041No
119TCF21TCF21
Entrez,  Source
transcription factor 2148560.0180.0042No
120PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha48830.0180.0031No
121NT5ENT5E
Entrez,  Source
5'-nucleotidase, ecto (CD73)49600.016-0.0020No
122PDE4DIPPDE4DIP
Entrez,  Source
phosphodiesterase 4D interacting protein (myomegalin)50220.016-0.0059No
123CYBBCYBB
Entrez,  Source
cytochrome b-245, beta polypeptide (chronic granulomatous disease)50280.016-0.0055No
124GUCY1A3GUCY1A3
Entrez,  Source
guanylate cyclase 1, soluble, alpha 350300.016-0.0048No
125NRP1NRP1
Entrez,  Source
neuropilin 150470.015-0.0053No
126PHLPPPHLPP
Entrez,  Source
PH domain and leucine rich repeat protein phosphatase50730.015-0.0064No
127NOSTRINNOSTRIN
Entrez,  Source
nitric oxide synthase trafficker52540.013-0.0196No
128FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES52690.013-0.0201No
129SERINC1SERINC1
Entrez,  Source
serine incorporator 152710.013-0.0195No
130PRKAA1PRKAA1
Entrez,  Source
protein kinase, AMP-activated, alpha 1 catalytic subunit53880.011-0.0279No
131UGP2UGP2
Entrez,  Source
UDP-glucose pyrophosphorylase 254490.011-0.0320No
132MAPTMAPT
Entrez,  Source
microtubule-associated protein tau54610.011-0.0323No
133SNF1LKSNF1LK
Entrez,  Source
SNF1-like kinase54690.010-0.0323No
134SLC2A3SLC2A3
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 354880.010-0.0332No
135EPN2EPN2
Entrez,  Source
epsin 255650.009-0.0386No
136HOMER1HOMER1
Entrez,  Source
homer homolog 1 (Drosophila)55980.009-0.0406No
137GATA3GATA3
Entrez,  Source
GATA binding protein 356820.008-0.0466No
138TSPAN5TSPAN5
Entrez,  Source
tetraspanin 557100.008-0.0483No
139RSNRSN
Entrez,  Source
restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)57290.008-0.0493No
140SPOPSPOP
Entrez,  Source
speckle-type POZ protein57340.008-0.0492No
141THBDTHBD
Entrez,  Source
thrombomodulin57420.007-0.0494No
142USP33USP33
Entrez,  Source
ubiquitin specific peptidase 3357480.007-0.0494No
143GPR116GPR116
Entrez,  Source
G protein-coupled receptor 11658180.007-0.0544No
144KLHL5KLHL5
Entrez,  Source
kelch-like 5 (Drosophila)58290.006-0.0548No
145MCL1MCL1
Entrez,  Source
myeloid cell leukemia sequence 1 (BCL2-related)58390.006-0.0552No
146UBE2V2UBE2V2
Entrez,  Source
ubiquitin-conjugating enzyme E2 variant 259090.005-0.0603No
147CAMK2DCAMK2D
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta59130.005-0.0602No
148WDFY1WDFY1
Entrez,  Source
WD repeat and FYVE domain containing 159150.005-0.0600No
149LMBRD1LMBRD1
Entrez,  Source
LMBR1 domain containing 159500.005-0.0624No
150PUM2PUM2
Entrez,  Source
pumilio homolog 2 (Drosophila)60770.004-0.0719No
151ERGERG
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog (avian)61880.003-0.0802No
152ARNTARNT
Entrez,  Source
aryl hydrocarbon receptor nuclear translocator63620.001-0.0935No
153ZFRZFR
Entrez,  Source
zinc finger RNA binding protein64170.000-0.0977No
154UMODUMOD
Entrez,  Source
uromodulin (uromucoid, Tamm-Horsfall glycoprotein)64190.000-0.0978No
155FABP4FABP4
Entrez,  Source
fatty acid binding protein 4, adipocyte6494-0.001-0.1034No
156ZHX1ZHX1
Entrez,  Source
zinc fingers and homeoboxes 16760-0.003-0.1236No
157WWP1WWP1
Entrez,  Source
WW domain containing E3 ubiquitin protein ligase 16766-0.003-0.1238No
158MYO1BMYO1B
Entrez,  Source
myosin IB6819-0.004-0.1276No
159ST8SIA4ST8SIA4
Entrez,  Source
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 46893-0.005-0.1330No
160PPP1R2PPP1R2
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 26926-0.005-0.1353No
161TSPAN12TSPAN12
Entrez,  Source
tetraspanin 126950-0.005-0.1368No
162VPS54VPS54
Entrez,  Source
vacuolar protein sorting 54 (S. cerevisiae)6985-0.005-0.1391No
163TOB1TOB1
Entrez,  Source
transducer of ERBB2, 16990-0.006-0.1392No
164RPS6KB1RPS6KB1
Entrez,  Source
ribosomal protein S6 kinase, 70kDa, polypeptide 17068-0.006-0.1448No
165MORF4L1MORF4L1
Entrez,  Source
mortality factor 4 like 17124-0.007-0.1487No
166NID1NID1
Entrez,  Source
nidogen 17136-0.007-0.1492No
167PON2PON2
Entrez,  Source
paraoxonase 27149-0.007-0.1497No
168CXCR4CXCR4
Entrez,  Source
chemokine (C-X-C motif) receptor 47175-0.007-0.1513No
169EFNB1EFNB1
Entrez,  Source
ephrin-B17246-0.008-0.1563No
170ART3ART3
Entrez,  Source
ADP-ribosyltransferase 37305-0.009-0.1603No
171FOXC2FOXC2
Entrez,  Source
forkhead box C2 (MFH-1, mesenchyme forkhead 1)7377-0.009-0.1653No
172ITGB5ITGB5
Entrez,  Source
integrin, beta 57411-0.010-0.1674No
173CD97CD97
Entrez,  Source
CD97 molecule7419-0.010-0.1675No
174ANXA1ANXA1
Entrez,  Source
annexin A17517-0.011-0.1744No
175PPAP2BPPAP2B
Entrez,  Source
phosphatidic acid phosphatase type 2B7532-0.011-0.1749No
176EBAG9EBAG9
Entrez,  Source
estrogen receptor binding site associated, antigen, 97572-0.011-0.1774No
177HTRA1HTRA1
Entrez,  Source
HtrA serine peptidase 17663-0.012-0.1837No
178TMOD3TMOD3
Entrez,  Source
tropomodulin 3 (ubiquitous)7774-0.013-0.1915No
179STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa7778-0.013-0.1911No
180NEDD9NEDD9
Entrez,  Source
neural precursor cell expressed, developmentally down-regulated 97794-0.013-0.1916No
181SONSON
Entrez,  Source
SON DNA binding protein7838-0.014-0.1942No
182EXOC8EXOC8
Entrez,  Source
exocyst complex component 87932-0.015-0.2006No
183MAFBMAFB
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)7949-0.015-0.2011No
184PBX2PBX2
Entrez,  Source
pre-B-cell leukemia transcription factor 28086-0.017-0.2108No
185CDC73CDC73
Entrez,  Source
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)8134-0.017-0.2135No
186CLCA2CLCA2
Entrez,  Source
chloride channel, calcium activated, family member 28169-0.017-0.2153No
187NSFNSF
Entrez,  Source
N-ethylmaleimide-sensitive factor8257-0.018-0.2211No
188LYSTLYST
Entrez,  Source
lysosomal trafficking regulator8300-0.019-0.2234No
189LEPREL1LEPREL1
Entrez,  Source
leprecan-like 18320-0.019-0.2239No
190CLIC5CLIC5
Entrez,  Source
chloride intracellular channel 58412-0.020-0.2300No
191INPP4AINPP4A
Entrez,  Source
inositol polyphosphate-4-phosphatase, type I, 107kDa8444-0.020-0.2314No
192JAK1JAK1
Entrez,  Source
Janus kinase 1 (a protein tyrosine kinase)8495-0.021-0.2342No
193IL13RA1IL13RA1
Entrez,  Source
interleukin 13 receptor, alpha 18528-0.021-0.2356No
194HHEXHHEX
Entrez,  Source
homeobox, hematopoietically expressed8540-0.021-0.2354No
195MGLLMGLL
Entrez,  Source
monoglyceride lipase8545-0.021-0.2347No
196SULF2SULF2
Entrez,  Source
sulfatase 28626-0.022-0.2398No
197GRK5GRK5
Entrez,  Source
G protein-coupled receptor kinase 58649-0.022-0.2403No
198HIP1HIP1
Entrez,  Source
huntingtin interacting protein 18701-0.023-0.2431No
199GLRX2GLRX2
Entrez,  Source
glutaredoxin 28756-0.023-0.2461No
200TMEM30ATMEM30A
Entrez,  Source
transmembrane protein 30A8787-0.024-0.2473No
201LYPLA1LYPLA1
Entrez,  Source
lysophospholipase I8796-0.024-0.2467No
202SERINC3SERINC3
Entrez,  Source
serine incorporator 38838-0.024-0.2487No
203TMEM33TMEM33
Entrez,  Source
transmembrane protein 338854-0.025-0.2486No
204DSCR1DSCR1
Entrez,  Source
Down syndrome critical region gene 18894-0.025-0.2504No
205PTGER4PTGER4
Entrez,  Source
prostaglandin E receptor 4 (subtype EP4)8928-0.025-0.2517No
206SYBL1SYBL1
Entrez,  Source
synaptobrevin-like 18932-0.025-0.2507No
207FLI1FLI1
Entrez,  Source
Friend leukemia virus integration 19098-0.027-0.2620No
208MERTKMERTK
Entrez,  Source
c-mer proto-oncogene tyrosine kinase9123-0.027-0.2626No
209VAMP5VAMP5
Entrez,  Source
vesicle-associated membrane protein 5 (myobrevin)9126-0.027-0.2614No
210DEGS1DEGS1
Entrez,  Source
degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)9137-0.027-0.2608No
211PDE4DPDE4D
Entrez,  Source
phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)9157-0.028-0.2609No
212IFI35IFI35
Entrez,  Source
interferon-induced protein 359166-0.028-0.2601No
213TPP1TPP1
Entrez,  Source
tripeptidyl peptidase I9225-0.028-0.2632No
214YIPF4YIPF4
Entrez,  Source
Yip1 domain family, member 49252-0.029-0.2638No
215P2RX4P2RX4
Entrez,  Source
purinergic receptor P2X, ligand-gated ion channel, 49274-0.029-0.2640No
216CALM1CALM1
Entrez,  Source
calmodulin 1 (phosphorylase kinase, delta)9285-0.029-0.2634No
217SH3GLB1SH3GLB1
Entrez,  Source
SH3-domain GRB2-like endophilin B19390-0.030-0.2699No
218PIK3CAPIK3CA
Entrez,  Source
phosphoinositide-3-kinase, catalytic, alpha polypeptide9438-0.031-0.2720No
219CSNK1G3CSNK1G3
Entrez,  Source
casein kinase 1, gamma 39458-0.031-0.2719No
220MTM1MTM1
Entrez,  Source
myotubularin 19464-0.031-0.2708No
221POLBPOLB
Entrez,  Source
polymerase (DNA directed), beta9596-0.033-0.2793No
222RAPGEF4RAPGEF4
Entrez,  Source
Rap guanine nucleotide exchange factor (GEF) 49637-0.033-0.2807No
223NPR3NPR3
Entrez,  Source
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)9749-0.034-0.2875No
224SLCO2A1SLCO2A1
Entrez,  Source
solute carrier organic anion transporter family, member 2A19760-0.035-0.2866No
225RAPGEF5RAPGEF5
Entrez,  Source
Rap guanine nucleotide exchange factor (GEF) 59858-0.036-0.2923No
226TSPAN2TSPAN2
Entrez,  Source
tetraspanin 29908-0.036-0.2943No
227IL6STIL6ST
Entrez,  Source
interleukin 6 signal transducer (gp130, oncostatin M receptor)9951-0.037-0.2957No
228CASTCAST
Entrez,  Source
calpastatin10118-0.039-0.3066No
229RGS2RGS2
Entrez,  Source
regulator of G-protein signalling 2, 24kDa10143-0.039-0.3065No
230ROCK1ROCK1
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 110218-0.040-0.3103No
231TMEM106BTMEM106B
Entrez,  Source
transmembrane protein 106B10252-0.040-0.3108No
232PROS1PROS1
Entrez,  Source
protein S (alpha)10274-0.040-0.3105No
233DBTDBT
Entrez,  Source
dihydrolipoamide branched chain transacylase E210335-0.041-0.3131No
234HAGHHAGH
Entrez,  Source
hydroxyacylglutathione hydrolase10339-0.041-0.3113No
235TAOK1TAOK1
Entrez,  Source
TAO kinase 110365-0.041-0.3112No
236PLCL1PLCL1
Entrez,  Source
phospholipase C-like 110415-0.042-0.3128No
237GNB1GNB1
Entrez,  Source
guanine nucleotide binding protein (G protein), beta polypeptide 110542-0.044-0.3204No
238OPTNOPTN
Entrez,  Source
optineurin10558-0.044-0.3193No
239GRM7GRM7
Entrez,  Source
glutamate receptor, metabotropic 710566-0.044-0.3177No
240TRIM23TRIM23
Entrez,  Source
tripartite motif-containing 2310616-0.045-0.3193No
241LASP1LASP1
Entrez,  Source
LIM and SH3 protein 110631-0.045-0.3181No
242PTPRJPTPRJ
Entrez,  Source
protein tyrosine phosphatase, receptor type, J10684-0.046-0.3199No
243RBBP6RBBP6
Entrez,  Source
retinoblastoma binding protein 610819-0.048-0.3278No
244RAP1BRAP1B
Entrez,  Source
RAP1B, member of RAS oncogene family10907-0.050-0.3320Yes
245CRKCRK
Entrez,  Source
v-crk sarcoma virus CT10 oncogene homolog (avian)10930-0.050-0.3313Yes
246MYO1EMYO1E
Entrez,  Source
myosin IE10936-0.050-0.3292Yes
247PRG1PRG1
Entrez,  Source
proteoglycan 1, secretory granule10939-0.050-0.3269Yes
248LNPEPLNPEP
Entrez,  Source
leucyl/cystinyl aminopeptidase10953-0.050-0.3254Yes
249PLEKHC1PLEKHC1
Entrez,  Source
pleckstrin homology domain containing, family C (with FERM domain) member 110973-0.051-0.3243Yes
250SPRED2SPRED2
Entrez,  Source
sprouty-related, EVH1 domain containing 210977-0.051-0.3221Yes
251CTBSCTBS
Entrez,  Source
chitobiase, di-N-acetyl-11010-0.051-0.3220Yes
252ITGB1ITGB1
Entrez,  Source
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)11016-0.051-0.3199Yes
253SLC17A5SLC17A5
Entrez,  Source
solute carrier family 17 (anion/sugar transporter), member 511064-0.052-0.3209Yes
254EP300EP300
Entrez,  Source
E1A binding protein p30011127-0.053-0.3231Yes
255STRNSTRN
Entrez,  Source
striatin, calmodulin binding protein11173-0.054-0.3239Yes
256ACBD5ACBD5
Entrez,  Source
acyl-Coenzyme A binding domain containing 511261-0.056-0.3278Yes
257ACSL4ACSL4
Entrez,  Source
acyl-CoA synthetase long-chain family member 411316-0.057-0.3291Yes
258CYP20A1CYP20A1
Entrez,  Source
cytochrome P450, family 20, subfamily A, polypeptide 111335-0.058-0.3277Yes
259PPM2CPPM2C
Entrez,  Source
protein phosphatase 2C, magnesium-dependent, catalytic subunit11399-0.059-0.3296Yes
260ARAFARAF
Entrez,  Source
v-raf murine sarcoma 3611 viral oncogene homolog11403-0.059-0.3270Yes
261SLC38A4SLC38A4
Entrez,  Source
solute carrier family 38, member 411430-0.059-0.3260Yes
262ST3GAL6ST3GAL6
Entrez,  Source
ST3 beta-galactoside alpha-2,3-sialyltransferase 611435-0.059-0.3234Yes
263KIF1BKIF1B
Entrez,  Source
kinesin family member 1B11447-0.059-0.3213Yes
264ARRB1ARRB1
Entrez,  Source
arrestin, beta 111454-0.060-0.3189Yes
265ZFHX1BZFHX1B
Entrez,  Source
zinc finger homeobox 1b11458-0.060-0.3162Yes
266PLD1PLD1
Entrez,  Source
phospholipase D1, phosphatidylcholine-specific11478-0.060-0.3147Yes
267TRPC1TRPC1
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 111504-0.060-0.3136Yes
268DSPDSP
Entrez,  Source
desmoplakin11506-0.060-0.3107Yes
269SAMD8SAMD8
Entrez,  Source
sterile alpha motif domain containing 811530-0.061-0.3095Yes
270CRSP3CRSP3
Entrez,  Source
cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa11567-0.062-0.3092Yes
271SH2D4ASH2D4A
Entrez,  Source
SH2 domain containing 4A11614-0.063-0.3096Yes
272CALM2CALM2
Entrez,  Source
calmodulin 2 (phosphorylase kinase, delta)11629-0.063-0.3076Yes
273TACC1TACC1
Entrez,  Source
transforming, acidic coiled-coil containing protein 111650-0.064-0.3060Yes
274CRYABCRYAB
Entrez,  Source
crystallin, alpha B11652-0.064-0.3030Yes
275PPAP2APPAP2A
Entrez,  Source
phosphatidic acid phosphatase type 2A11707-0.065-0.3039Yes
276PGGT1BPGGT1B
Entrez,  Source
protein geranylgeranyltransferase type I, beta subunit11723-0.065-0.3019Yes
277KIF5BKIF5B
Entrez,  Source
kinesin family member 5B11786-0.067-0.3033Yes
278STXBP3STXBP3
Entrez,  Source
syntaxin binding protein 311792-0.067-0.3004Yes
279OSBPL5OSBPL5
Entrez,  Source
oxysterol binding protein-like 511832-0.068-0.3001Yes
280EHD4EHD4
Entrez,  Source
EH-domain containing 411851-0.069-0.2981Yes
281SH3BP5SH3BP5
Entrez,  Source
SH3-domain binding protein 5 (BTK-associated)11864-0.069-0.2956Yes
282ABCA5ABCA5
Entrez,  Source
ATP-binding cassette, sub-family A (ABC1), member 511882-0.070-0.2935Yes
283PLSCR4PLSCR4
Entrez,  Source
phospholipid scramblase 411904-0.070-0.2916Yes
284CFLARCFLAR
Entrez,  Source
CASP8 and FADD-like apoptosis regulator11917-0.070-0.2891Yes
285NCOR1NCOR1
Entrez,  Source
nuclear receptor co-repressor 111956-0.071-0.2885Yes
286CBARA1CBARA1
Entrez,  Source
calcium binding atopy-related autoantigen 111983-0.072-0.2870Yes
287ING3ING3
Entrez,  Source
inhibitor of growth family, member 311994-0.073-0.2841Yes
288RALBRALB
Entrez,  Source
v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)12089-0.076-0.2877Yes
289TMEM23TMEM23
Entrez,  Source
transmembrane protein 2312115-0.076-0.2858Yes
290VIMVIM
Entrez,  Source
vimentin12125-0.077-0.2827Yes
291BMPR1ABMPR1A
Entrez,  Source
bone morphogenetic protein receptor, type IA12130-0.077-0.2793Yes
292GYG1GYG1
Entrez,  Source
glycogenin 112237-0.081-0.2834Yes
293ELF1ELF1
Entrez,  Source
E74-like factor 1 (ets domain transcription factor)12250-0.081-0.2804Yes
294ANXA4ANXA4
Entrez,  Source
annexin A412281-0.082-0.2786Yes
295HIVEP2HIVEP2
Entrez,  Source
human immunodeficiency virus type I enhancer binding protein 212335-0.085-0.2785Yes
296FUT11FUT11
Entrez,  Source
fucosyltransferase 11 (alpha (1,3) fucosyltransferase)12339-0.085-0.2746Yes
297CD47CD47
Entrez,  Source
CD47 molecule12518-0.093-0.2837Yes
298TIMP3TIMP3
Entrez,  Source
TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory)12540-0.094-0.2807Yes
299SIRPASIRPA
Entrez,  Source
signal-regulatory protein alpha12585-0.096-0.2794Yes
300TOP1MTTOP1MT
Entrez,  Source
topoisomerase (DNA) I, mitochondrial12617-0.098-0.2770Yes
301STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)12679-0.101-0.2767Yes
302PER2PER2
Entrez,  Source
period homolog 2 (Drosophila)12697-0.103-0.2729Yes
303TNFRSF11BTNFRSF11B
Entrez,  Source
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)12718-0.104-0.2693Yes
304PARP4PARP4
Entrez,  Source
poly (ADP-ribose) polymerase family, member 412762-0.108-0.2673Yes
305IL2RGIL2RG
Entrez,  Source
interleukin 2 receptor, gamma (severe combined immunodeficiency)12775-0.109-0.2629Yes
306RBMS1RBMS1
Entrez,  Source
RNA binding motif, single stranded interacting protein 112785-0.110-0.2582Yes
307WSB2WSB2
Entrez,  Source
WD repeat and SOCS box-containing 212797-0.110-0.2536Yes
308SGKSGK
Entrez,  Source
serum/glucocorticoid regulated kinase12799-0.110-0.2483Yes
309DYNC1LI2DYNC1LI2
Entrez,  Source
dynein, cytoplasmic 1, light intermediate chain 212827-0.113-0.2448Yes
310DSCR1L1DSCR1L1
Entrez,  Source
Down syndrome critical region gene 1-like 112846-0.115-0.2405Yes
311KLF4KLF4
Entrez,  Source
Kruppel-like factor 4 (gut)12854-0.115-0.2354Yes
312MYO1CMYO1C
Entrez,  Source
myosin IC12875-0.118-0.2311Yes
313RASA2RASA2
Entrez,  Source
RAS p21 protein activator 212895-0.120-0.2266Yes
314CITED2CITED2
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 212899-0.121-0.2209Yes
315DPP4DPP4
Entrez,  Source
dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)12933-0.125-0.2173Yes
316TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)12937-0.125-0.2114Yes
317DPYSL2DPYSL2
Entrez,  Source
dihydropyrimidinase-like 212948-0.126-0.2059Yes
318DNAJB4DNAJB4
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 412953-0.126-0.2000Yes
319ADAMTS5ADAMTS5
Entrez,  Source
ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2)12954-0.127-0.1938Yes
320NFKBIANFKBIA
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha12964-0.127-0.1882Yes
321BICD2BICD2
Entrez,  Source
bicaudal D homolog 2 (Drosophila)13035-0.137-0.1868Yes
322TGFBR2TGFBR2
Entrez,  Source
transforming growth factor, beta receptor II (70/80kDa)13036-0.137-0.1801Yes
323LZTFL1LZTFL1
Entrez,  Source
leucine zipper transcription factor-like 113050-0.140-0.1742Yes
324PIP5K2BPIP5K2B
Entrez,  Source
phosphatidylinositol-4-phosphate 5-kinase, type II, beta13070-0.143-0.1686Yes
325CAV2CAV2
Entrez,  Source
caveolin 213082-0.146-0.1623Yes
326PDLIM2PDLIM2
Entrez,  Source
PDZ and LIM domain 2 (mystique)13086-0.147-0.1553Yes
327RRAS2RRAS2
Entrez,  Source
related RAS viral (r-ras) oncogene homolog 213088-0.147-0.1481Yes
328ETS1ETS1
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)13097-0.150-0.1413Yes
329TRAK2TRAK2
Entrez,  Source
trafficking protein, kinesin binding 213124-0.154-0.1357Yes
330TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)13153-0.163-0.1299Yes
331SOS2SOS2
Entrez,  Source
son of sevenless homolog 2 (Drosophila)13162-0.167-0.1223Yes
332SCHIP1SCHIP1
Entrez,  Source
schwannomin interacting protein 113195-0.185-0.1156Yes
333FRKFRK
Entrez,  Source
fyn-related kinase13199-0.189-0.1065Yes
334SERINC5SERINC5
Entrez,  Source
serine incorporator 513200-0.190-0.0972Yes
335PLCE1PLCE1
Entrez,  Source
phospholipase C, epsilon 113205-0.194-0.0880Yes
336PLATPLAT
Entrez,  Source
plasminogen activator, tissue13214-0.201-0.0787Yes
337CYP4B1CYP4B1
Entrez,  Source
cytochrome P450, family 4, subfamily B, polypeptide 113244-0.218-0.0702Yes
338MYADMMYADM
Entrez,  Source
myeloid-associated differentiation marker13269-0.239-0.0603Yes
339PDE4BPDE4B
Entrez,  Source
phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)13271-0.241-0.0485Yes
340LMO7LMO7
Entrez,  Source
LIM domain 713278-0.252-0.0365Yes
341AVPR1AAVPR1A
Entrez,  Source
arginine vasopressin receptor 1A13282-0.262-0.0238Yes
342CTGFCTGF
Entrez,  Source
connective tissue growth factor13284-0.263-0.0110Yes
343AHNAKAHNAK
Entrez,  Source
AHNAK nucleoprotein (desmoyokin)13307-0.3120.0027Yes
Table: GSEA details [plain text format]



Fig 2: POD1_KO_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: POD1_KO_DN: Random ES distribution   
Gene set null distribution of ES for POD1_KO_DN