Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | REN_E2F1_TARGETS |
| Enrichment Score (ES) | -0.5661892 |
| Normalized Enrichment Score (NES) | -1.7138072 |
| Nominal p-value | 0.00990099 |
| FDR q-value | 0.14961812 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CALR | CALR Entrez, Source | calreticulin | 381 | 0.127 | 0.0475 | No |
| 2 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1411 | 0.077 | 0.0165 | No |
| 3 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 2916 | 0.044 | -0.0699 | No |
| 4 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 3869 | 0.030 | -0.1234 | No |
| 5 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3887 | 0.030 | -0.1069 | No |
| 6 | NCL | NCL Entrez, Source | nucleolin | 4105 | 0.027 | -0.1071 | No |
| 7 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 4450 | 0.023 | -0.1194 | No |
| 8 | PRPSAP1 | PRPSAP1 Entrez, Source | phosphoribosyl pyrophosphate synthetase-associated protein 1 | 6235 | 0.002 | -0.2521 | No |
| 9 | SLC3A2 | SLC3A2 Entrez, Source | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 7310 | -0.009 | -0.3275 | No |
| 10 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 8303 | -0.019 | -0.3908 | No |
| 11 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 8391 | -0.020 | -0.3857 | No |
| 12 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 9334 | -0.029 | -0.4388 | No |
| 13 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 9337 | -0.029 | -0.4213 | No |
| 14 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 9409 | -0.030 | -0.4085 | No |
| 15 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 9718 | -0.034 | -0.4112 | No |
| 16 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 10249 | -0.040 | -0.4271 | No |
| 17 | CALM2 | CALM2 Entrez, Source | calmodulin 2 (phosphorylase kinase, delta) | 11629 | -0.063 | -0.4928 | No |
| 18 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 12607 | -0.097 | -0.5081 | Yes |
| 19 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 12758 | -0.107 | -0.4551 | Yes |
| 20 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12915 | -0.123 | -0.3934 | Yes |
| 21 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 13133 | -0.158 | -0.3155 | Yes |
| 22 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13232 | -0.213 | -0.1954 | Yes |
| 23 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13314 | -0.341 | 0.0021 | Yes |
