Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | REPRODUCTION |
| Enrichment Score (ES) | 0.33832225 |
| Normalized Enrichment Score (NES) | 1.4662795 |
| Nominal p-value | 0.007858546 |
| FDR q-value | 0.29325995 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GPR64 | GPR64 Entrez, Source | G protein-coupled receptor 64 | 39 | 0.227 | 0.0290 | Yes |
| 2 | HIST1H1T | HIST1H1T Entrez, Source | histone cluster 1, H1t | 69 | 0.192 | 0.0539 | Yes |
| 3 | ACE2 | ACE2 Entrez, Source | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 | 159 | 0.157 | 0.0692 | Yes |
| 4 | HMGCR | HMGCR Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 250 | 0.141 | 0.0823 | Yes |
| 5 | WNT7A | WNT7A Entrez, Source | wingless-type MMTV integration site family, member 7A | 251 | 0.141 | 0.1022 | Yes |
| 6 | LHCGR | LHCGR Entrez, Source | luteinizing hormone/choriogonadotropin receptor | 330 | 0.132 | 0.1149 | Yes |
| 7 | CYP17A1 | CYP17A1 Entrez, Source | cytochrome P450, family 17, subfamily A, polypeptide 1 | 397 | 0.126 | 0.1276 | Yes |
| 8 | CRHR1 | CRHR1 Entrez, Source | corticotropin releasing hormone receptor 1 | 473 | 0.120 | 0.1388 | Yes |
| 9 | SYCP1 | SYCP1 Entrez, Source | synaptonemal complex protein 1 | 673 | 0.105 | 0.1386 | Yes |
| 10 | KHDRBS3 | KHDRBS3 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 3 | 681 | 0.105 | 0.1529 | Yes |
| 11 | ADAM2 | ADAM2 Entrez, Source | ADAM metallopeptidase domain 2 (fertilin beta) | 750 | 0.102 | 0.1621 | Yes |
| 12 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 763 | 0.101 | 0.1755 | Yes |
| 13 | PRLHR | PRLHR Entrez, Source | prolactin releasing hormone receptor | 822 | 0.099 | 0.1850 | Yes |
| 14 | OPRK1 | OPRK1 Entrez, Source | opioid receptor, kappa 1 | 1142 | 0.086 | 0.1729 | Yes |
| 15 | TAC1 | TAC1 Entrez, Source | tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma) | 1171 | 0.085 | 0.1827 | Yes |
| 16 | AMH | AMH Entrez, Source | anti-Mullerian hormone | 1244 | 0.082 | 0.1889 | Yes |
| 17 | CD4 | CD4 Entrez, Source | CD4 molecule | 1266 | 0.081 | 0.1988 | Yes |
| 18 | DUSP13 | DUSP13 Entrez, Source | dual specificity phosphatase 13 | 1373 | 0.078 | 0.2018 | Yes |
| 19 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 1559 | 0.073 | 0.1981 | Yes |
| 20 | GDF9 | GDF9 Entrez, Source | growth differentiation factor 9 | 1587 | 0.073 | 0.2063 | Yes |
| 21 | PZP | PZP Entrez, Source | pregnancy-zone protein | 1618 | 0.072 | 0.2142 | Yes |
| 22 | DDX25 | DDX25 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 | 1658 | 0.071 | 0.2212 | Yes |
| 23 | PTGFR | PTGFR Entrez, Source | prostaglandin F receptor (FP) | 1661 | 0.071 | 0.2310 | Yes |
| 24 | LHB | LHB Entrez, Source | luteinizing hormone beta polypeptide | 1684 | 0.070 | 0.2393 | Yes |
| 25 | LIPE | LIPE Entrez, Source | lipase, hormone-sensitive | 1739 | 0.069 | 0.2449 | Yes |
| 26 | GGN | GGN Entrez, Source | gametogenetin | 1864 | 0.066 | 0.2448 | Yes |
| 27 | SYCP3 | SYCP3 Entrez, Source | synaptonemal complex protein 3 | 1938 | 0.064 | 0.2482 | Yes |
| 28 | TSPY1 | TSPY1 Entrez, Source | testis specific protein, Y-linked 1 | 1967 | 0.063 | 0.2550 | Yes |
| 29 | PNMA1 | PNMA1 Entrez, Source | paraneoplastic antigen MA1 | 1978 | 0.063 | 0.2632 | Yes |
| 30 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 2009 | 0.062 | 0.2697 | Yes |
| 31 | SERPINA5 | SERPINA5 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 2042 | 0.061 | 0.2759 | Yes |
| 32 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 2110 | 0.060 | 0.2792 | Yes |
| 33 | OXTR | OXTR Entrez, Source | oxytocin receptor | 2184 | 0.058 | 0.2819 | Yes |
| 34 | ADM | ADM Entrez, Source | adrenomedullin | 2189 | 0.058 | 0.2897 | Yes |
| 35 | BCL2L10 | BCL2L10 Entrez, Source | BCL2-like 10 (apoptosis facilitator) | 2279 | 0.056 | 0.2908 | Yes |
| 36 | AKAP4 | AKAP4 Entrez, Source | A kinase (PRKA) anchor protein 4 | 2281 | 0.056 | 0.2986 | Yes |
| 37 | BRD2 | BRD2 Entrez, Source | bromodomain containing 2 | 2310 | 0.055 | 0.3043 | Yes |
| 38 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 2415 | 0.053 | 0.3039 | Yes |
| 39 | GHRL | GHRL Entrez, Source | ghrelin/obestatin preprohormone | 2417 | 0.053 | 0.3114 | Yes |
| 40 | JAG2 | JAG2 Entrez, Source | jagged 2 | 2469 | 0.052 | 0.3149 | Yes |
| 41 | ZP2 | ZP2 Entrez, Source | zona pellucida glycoprotein 2 (sperm receptor) | 2481 | 0.052 | 0.3214 | Yes |
| 42 | CEP57 | CEP57 Entrez, Source | centrosomal protein 57kDa | 2503 | 0.052 | 0.3270 | Yes |
| 43 | CSDE1 | CSDE1 Entrez, Source | cold shock domain containing E1, RNA-binding | 2537 | 0.051 | 0.3317 | Yes |
| 44 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 2635 | 0.049 | 0.3313 | Yes |
| 45 | BYSL | BYSL Entrez, Source | bystin-like | 2678 | 0.048 | 0.3349 | Yes |
| 46 | COL16A1 | COL16A1 Entrez, Source | collagen, type XVI, alpha 1 | 2723 | 0.048 | 0.3383 | Yes |
| 47 | PTTG1 | PTTG1 Entrez, Source | pituitary tumor-transforming 1 | 2878 | 0.045 | 0.3330 | No |
| 48 | BMP15 | BMP15 Entrez, Source | bone morphogenetic protein 15 | 2907 | 0.045 | 0.3371 | No |
| 49 | NR0B1 | NR0B1 Entrez, Source | nuclear receptor subfamily 0, group B, member 1 | 3167 | 0.041 | 0.3233 | No |
| 50 | EREG | EREG Entrez, Source | epiregulin | 3391 | 0.037 | 0.3116 | No |
| 51 | SPAG4 | SPAG4 Entrez, Source | sperm associated antigen 4 | 3489 | 0.035 | 0.3092 | No |
| 52 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 3593 | 0.034 | 0.3062 | No |
| 53 | PRLR | PRLR Entrez, Source | prolactin receptor | 3608 | 0.034 | 0.3099 | No |
| 54 | PPARD | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 3654 | 0.033 | 0.3111 | No |
| 55 | MTL5 | MTL5 Entrez, Source | metallothionein-like 5, testis-specific (tesmin) | 3908 | 0.030 | 0.2961 | No |
| 56 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 4134 | 0.027 | 0.2828 | No |
| 57 | SFRP4 | SFRP4 Entrez, Source | secreted frizzled-related protein 4 | 4144 | 0.026 | 0.2859 | No |
| 58 | TSGA10 | TSGA10 Entrez, Source | testis specific, 10 | 4167 | 0.026 | 0.2879 | No |
| 59 | AGT | AGT Entrez, Source | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 4353 | 0.024 | 0.2772 | No |
| 60 | HSD17B3 | HSD17B3 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 3 | 4399 | 0.023 | 0.2771 | No |
| 61 | CRH | CRH Entrez, Source | corticotropin releasing hormone | 4615 | 0.021 | 0.2637 | No |
| 62 | DNALI1 | DNALI1 Entrez, Source | dynein, axonemal, light intermediate chain 1 | 4753 | 0.019 | 0.2560 | No |
| 63 | TOB2 | TOB2 Entrez, Source | transducer of ERBB2, 2 | 4866 | 0.018 | 0.2501 | No |
| 64 | FCGRT | FCGRT Entrez, Source | Fc fragment of IgG, receptor, transporter, alpha | 4923 | 0.017 | 0.2482 | No |
| 65 | PRM2 | PRM2 Entrez, Source | protamine 2 | 4958 | 0.016 | 0.2479 | No |
| 66 | NPM2 | NPM2 Entrez, Source | nucleophosmin/nucleoplasmin, 2 | 5044 | 0.016 | 0.2437 | No |
| 67 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 5344 | 0.012 | 0.2227 | No |
| 68 | CSH2 | CSH2 Entrez, Source | chorionic somatomammotropin hormone 2 | 5473 | 0.010 | 0.2145 | No |
| 69 | FOXJ1 | FOXJ1 Entrez, Source | forkhead box J1 | 5483 | 0.010 | 0.2153 | No |
| 70 | RRAGA | RRAGA Entrez, Source | Ras-related GTP binding A | 5543 | 0.010 | 0.2122 | No |
| 71 | FSHB | FSHB Entrez, Source | follicle stimulating hormone, beta polypeptide | 5638 | 0.009 | 0.2063 | No |
| 72 | ACR | ACR Entrez, Source | acrosin | 5683 | 0.008 | 0.2041 | No |
| 73 | ABCB9 | ABCB9 Entrez, Source | ATP-binding cassette, sub-family B (MDR/TAP), member 9 | 5872 | 0.006 | 0.1907 | No |
| 74 | SHH | SHH Entrez, Source | sonic hedgehog homolog (Drosophila) | 5903 | 0.005 | 0.1892 | No |
| 75 | SCGB1A1 | SCGB1A1 Entrez, Source | secretoglobin, family 1A, member 1 (uteroglobin) | 6181 | 0.003 | 0.1686 | No |
| 76 | LIG3 | LIG3 Entrez, Source | ligase III, DNA, ATP-dependent | 6312 | 0.001 | 0.1589 | No |
| 77 | BCL2L2 | BCL2L2 Entrez, Source | BCL2-like 2 | 6379 | 0.000 | 0.1540 | No |
| 78 | WWP1 | WWP1 Entrez, Source | WW domain containing E3 ubiquitin protein ligase 1 | 6766 | -0.003 | 0.1252 | No |
| 79 | AXIN1 | AXIN1 Entrez, Source | axin 1 | 6776 | -0.004 | 0.1251 | No |
| 80 | AMHR2 | AMHR2 Entrez, Source | anti-Mullerian hormone receptor, type II | 6804 | -0.004 | 0.1235 | No |
| 81 | DNAJB13 | DNAJB13 Entrez, Source | DnaJ (Hsp40) related, subfamily B, member 13 | 6998 | -0.006 | 0.1097 | No |
| 82 | EIF2B4 | EIF2B4 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | 7111 | -0.007 | 0.1022 | No |
| 83 | DAZAP1 | DAZAP1 Entrez, Source | DAZ associated protein 1 | 7159 | -0.007 | 0.0996 | No |
| 84 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7350 | -0.009 | 0.0865 | No |
| 85 | HSPA2 | HSPA2 Entrez, Source | heat shock 70kDa protein 2 | 7468 | -0.010 | 0.0791 | No |
| 86 | TESK2 | TESK2 Entrez, Source | testis-specific kinase 2 | 7470 | -0.010 | 0.0804 | No |
| 87 | DEDD | DEDD Entrez, Source | death effector domain containing | 7472 | -0.010 | 0.0818 | No |
| 88 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 7532 | -0.011 | 0.0789 | No |
| 89 | PTHLH | PTHLH Entrez, Source | parathyroid hormone-like hormone | 7588 | -0.011 | 0.0763 | No |
| 90 | PPIA | PPIA Entrez, Source | peptidylprolyl isomerase A (cyclophilin A) | 7751 | -0.013 | 0.0659 | No |
| 91 | ADAM18 | ADAM18 Entrez, Source | ADAM metallopeptidase domain 18 | 7771 | -0.013 | 0.0663 | No |
| 92 | BAX | BAX Entrez, Source | BCL2-associated X protein | 7784 | -0.013 | 0.0673 | No |
| 93 | TESK1 | TESK1 Entrez, Source | testis-specific kinase 1 | 7833 | -0.014 | 0.0656 | No |
| 94 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 7978 | -0.015 | 0.0569 | No |
| 95 | GHSR | GHSR Entrez, Source | growth hormone secretagogue receptor | 8118 | -0.017 | 0.0487 | No |
| 96 | CD81 | CD81 Entrez, Source | CD81 molecule | 8145 | -0.017 | 0.0492 | No |
| 97 | RUVBL1 | RUVBL1 Entrez, Source | RuvB-like 1 (E. coli) | 8268 | -0.018 | 0.0425 | No |
| 98 | CLIC5 | CLIC5 Entrez, Source | chloride intracellular channel 5 | 8412 | -0.020 | 0.0345 | No |
| 99 | TARBP2 | TARBP2 Entrez, Source | Tar (HIV-1) RNA binding protein 2 | 8534 | -0.021 | 0.0283 | No |
| 100 | PRKAG1 | PRKAG1 Entrez, Source | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 8770 | -0.023 | 0.0138 | No |
| 101 | RPL29 | RPL29 Entrez, Source | ribosomal protein L29 | 8850 | -0.024 | 0.0113 | No |
| 102 | INSL3 | INSL3 Entrez, Source | insulin-like 3 (Leydig cell) | 8963 | -0.026 | 0.0064 | No |
| 103 | SMARCB1 | SMARCB1 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 9095 | -0.027 | 0.0003 | No |
| 104 | TNP1 | TNP1 Entrez, Source | transition protein 1 (during histone to protamine replacement) | 9171 | -0.028 | -0.0015 | No |
| 105 | PROK2 | PROK2 Entrez, Source | prokineticin 2 | 9205 | -0.028 | -0.0000 | No |
| 106 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 9337 | -0.029 | -0.0058 | No |
| 107 | DEAF1 | DEAF1 Entrez, Source | deformed epidermal autoregulatory factor 1 (Drosophila) | 9574 | -0.032 | -0.0191 | No |
| 108 | PICK1 | PICK1 Entrez, Source | protein interacting with PRKCA 1 | 9587 | -0.032 | -0.0154 | No |
| 109 | WFDC2 | WFDC2 Entrez, Source | WAP four-disulfide core domain 2 | 9661 | -0.033 | -0.0163 | No |
| 110 | ADCYAP1 | ADCYAP1 Entrez, Source | adenylate cyclase activating polypeptide 1 (pituitary) | 9783 | -0.035 | -0.0205 | No |
| 111 | VAPB | VAPB Entrez, Source | VAMP (vesicle-associated membrane protein)-associated protein B and C | 9787 | -0.035 | -0.0158 | No |
| 112 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 10216 | -0.040 | -0.0426 | No |
| 113 | EIF2B2 | EIF2B2 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa | 10336 | -0.041 | -0.0459 | No |
| 114 | CTBP1 | CTBP1 Entrez, Source | C-terminal binding protein 1 | 10344 | -0.041 | -0.0406 | No |
| 115 | EIF2B5 | EIF2B5 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa | 10572 | -0.044 | -0.0515 | No |
| 116 | PSG4 | PSG4 Entrez, Source | pregnancy specific beta-1-glycoprotein 4 | 10630 | -0.045 | -0.0495 | No |
| 117 | CENPI | CENPI Entrez, Source | centromere protein I | 10750 | -0.047 | -0.0519 | No |
| 118 | MKKS | MKKS Entrez, Source | McKusick-Kaufman syndrome | 10791 | -0.048 | -0.0482 | No |
| 119 | APLN | APLN Entrez, Source | apelin, AGTRL1 ligand | 10911 | -0.050 | -0.0501 | No |
| 120 | LNPEP | LNPEP Entrez, Source | leucyl/cystinyl aminopeptidase | 10953 | -0.050 | -0.0462 | No |
| 121 | TEAD3 | TEAD3 Entrez, Source | TEA domain family member 3 | 10976 | -0.051 | -0.0407 | No |
| 122 | AKAP3 | AKAP3 Entrez, Source | A kinase (PRKA) anchor protein 3 | 11171 | -0.054 | -0.0477 | No |
| 123 | AGPAT6 | AGPAT6 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta) | 11236 | -0.056 | -0.0447 | No |
| 124 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 11296 | -0.057 | -0.0412 | No |
| 125 | PPAP2A | PPAP2A Entrez, Source | phosphatidic acid phosphatase type 2A | 11707 | -0.065 | -0.0631 | No |
| 126 | CD9 | CD9 Entrez, Source | CD9 molecule | 11802 | -0.067 | -0.0607 | No |
| 127 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 11928 | -0.071 | -0.0602 | No |
| 128 | IDE | IDE Entrez, Source | insulin-degrading enzyme | 12040 | -0.074 | -0.0582 | No |
| 129 | CRISP1 | CRISP1 Entrez, Source | cysteine-rich secretory protein 1 | 12140 | -0.077 | -0.0548 | No |
| 130 | DEK | DEK Entrez, Source | DEK oncogene (DNA binding) | 12158 | -0.078 | -0.0451 | No |
| 131 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 12509 | -0.092 | -0.0587 | No |
| 132 | CRHBP | CRHBP Entrez, Source | corticotropin releasing hormone binding protein | 12709 | -0.104 | -0.0591 | No |
| 133 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 12847 | -0.115 | -0.0533 | No |
| 134 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 12853 | -0.115 | -0.0375 | No |
| 135 | SPA17 | SPA17 Entrez, Source | sperm autoantigenic protein 17 | 12957 | -0.127 | -0.0274 | No |
| 136 | IFT81 | IFT81 Entrez, Source | intraflagellar transport 81 homolog (Chlamydomonas) | 12967 | -0.128 | -0.0101 | No |
| 137 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13292 | -0.273 | 0.0038 | No |
