Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | S1P_SIGNALING |
| Enrichment Score (ES) | -0.5563125 |
| Normalized Enrichment Score (NES) | -1.6465251 |
| Nominal p-value | 0.022403259 |
| FDR q-value | 0.19699124 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SPHK1 | SPHK1 Entrez, Source | sphingosine kinase 1 | 1584 | 0.073 | -0.0648 | No |
| 2 | EDG1 | EDG1 Entrez, Source | endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 | 2463 | 0.052 | -0.0918 | No |
| 3 | MAPK4 | MAPK4 Entrez, Source | mitogen-activated protein kinase 4 | 3307 | 0.038 | -0.1266 | No |
| 4 | MAPK6 | MAPK6 Entrez, Source | mitogen-activated protein kinase 6 | 3705 | 0.032 | -0.1323 | No |
| 5 | SDCCAG8 | SDCCAG8 Entrez, Source | serologically defined colon cancer antigen 8 | 5485 | 0.010 | -0.2581 | No |
| 6 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 6842 | -0.004 | -0.3568 | No |
| 7 | GNAI3 | GNAI3 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 6944 | -0.005 | -0.3607 | No |
| 8 | AKT3 | AKT3 Entrez, Source | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 7266 | -0.008 | -0.3786 | No |
| 9 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 7331 | -0.009 | -0.3768 | No |
| 10 | MAPK7 | MAPK7 Entrez, Source | mitogen-activated protein kinase 7 | 7583 | -0.011 | -0.3872 | No |
| 11 | EDG8 | EDG8 Entrez, Source | endothelial differentiation, sphingolipid G-protein-coupled receptor, 8 | 7692 | -0.012 | -0.3861 | No |
| 12 | PLCB2 | PLCB2 Entrez, Source | phospholipase C, beta 2 | 9169 | -0.028 | -0.4763 | No |
| 13 | PLCB3 | PLCB3 Entrez, Source | phospholipase C, beta 3 (phosphatidylinositol-specific) | 10097 | -0.038 | -0.5174 | No |
| 14 | GNAI2 | GNAI2 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 10617 | -0.045 | -0.5228 | Yes |
| 15 | AKT1 | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 10753 | -0.047 | -0.4979 | Yes |
| 16 | MAPK12 | MAPK12 Entrez, Source | mitogen-activated protein kinase 12 | 11422 | -0.059 | -0.5040 | Yes |
| 17 | SPHK2 | SPHK2 Entrez, Source | sphingosine kinase 2 | 11926 | -0.071 | -0.4893 | Yes |
| 18 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12184 | -0.079 | -0.4498 | Yes |
| 19 | ASAH1 | ASAH1 Entrez, Source | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 12784 | -0.110 | -0.4132 | Yes |
| 20 | PLCB1 | PLCB1 Entrez, Source | phospholipase C, beta 1 (phosphoinositide-specific) | 12927 | -0.124 | -0.3313 | Yes |
| 21 | EDG5 | EDG5 Entrez, Source | endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 | 13254 | -0.222 | -0.1904 | Yes |
| 22 | SERPINH1 | SERPINH1 Entrez, Source | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 13285 | -0.265 | 0.0043 | Yes |
