Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | SANA_TNFA_ENDOTHELIAL_UP |
| Enrichment Score (ES) | -0.43738216 |
| Normalized Enrichment Score (NES) | -1.5097101 |
| Nominal p-value | 0.033864543 |
| FDR q-value | 0.27600724 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MX2 | MX2 Entrez, Source | myxovirus (influenza virus) resistance 2 (mouse) | 64 | 0.196 | 0.0454 | No |
| 2 | MMP10 | MMP10 Entrez, Source | matrix metallopeptidase 10 (stromelysin 2) | 249 | 0.141 | 0.0679 | No |
| 3 | IFIT1 | IFIT1 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 1 | 366 | 0.128 | 0.0921 | No |
| 4 | CX3CL1 | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 894 | 0.096 | 0.0770 | No |
| 5 | OAS1 | OAS1 Entrez, Source | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 980 | 0.092 | 0.0942 | No |
| 6 | INHBA | INHBA Entrez, Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 1174 | 0.085 | 0.1014 | No |
| 7 | UBD | UBD Entrez, Source | ubiquitin D | 1208 | 0.083 | 0.1203 | No |
| 8 | CASP1 | CASP1 Entrez, Source | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 1348 | 0.079 | 0.1301 | No |
| 9 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 1350 | 0.079 | 0.1502 | No |
| 10 | C1QTNF1 | C1QTNF1 Entrez, Source | C1q and tumor necrosis factor related protein 1 | 1384 | 0.078 | 0.1677 | No |
| 11 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 1805 | 0.067 | 0.1534 | No |
| 12 | LGALS9 | LGALS9 Entrez, Source | lectin, galactoside-binding, soluble, 9 (galectin 9) | 2245 | 0.056 | 0.1348 | No |
| 13 | CCL11 | CCL11 Entrez, Source | chemokine (C-C motif) ligand 11 | 2522 | 0.051 | 0.1272 | No |
| 14 | SLC15A3 | SLC15A3 Entrez, Source | solute carrier family 15, member 3 | 2965 | 0.044 | 0.1052 | No |
| 15 | CXCR7 | CXCR7 Entrez, Source | chemokine (C-X-C motif) receptor 7 | 2967 | 0.044 | 0.1162 | No |
| 16 | CSF1 | CSF1 Entrez, Source | colony stimulating factor 1 (macrophage) | 3375 | 0.037 | 0.0952 | No |
| 17 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 4412 | 0.023 | 0.0232 | No |
| 18 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 4601 | 0.021 | 0.0144 | No |
| 19 | DNAJA1 | DNAJA1 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 1 | 4679 | 0.020 | 0.0137 | No |
| 20 | FTH1 | FTH1 Entrez, Source | ferritin, heavy polypeptide 1 | 4858 | 0.018 | 0.0049 | No |
| 21 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 4868 | 0.018 | 0.0087 | No |
| 22 | CTHRC1 | CTHRC1 Entrez, Source | collagen triple helix repeat containing 1 | 6732 | -0.003 | -0.1305 | No |
| 23 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 6762 | -0.003 | -0.1318 | No |
| 24 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 7608 | -0.012 | -0.1924 | No |
| 25 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 7845 | -0.014 | -0.2065 | No |
| 26 | TLR2 | TLR2 Entrez, Source | toll-like receptor 2 | 8424 | -0.020 | -0.2449 | No |
| 27 | DHRS8 | DHRS8 Entrez, Source | dehydrogenase/reductase (SDR family) member 8 | 9582 | -0.032 | -0.3236 | No |
| 28 | SLC7A2 | SLC7A2 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 9632 | -0.033 | -0.3188 | No |
| 29 | PLA1A | PLA1A Entrez, Source | phospholipase A1 member A | 10432 | -0.042 | -0.3680 | No |
| 30 | BPGM | BPGM Entrez, Source | 2,3-bisphosphoglycerate mutase | 11356 | -0.058 | -0.4225 | Yes |
| 31 | OXR1 | OXR1 Entrez, Source | oxidation resistance 1 | 11452 | -0.060 | -0.4144 | Yes |
| 32 | CCL7 | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 11508 | -0.061 | -0.4030 | Yes |
| 33 | BST2 | BST2 Entrez, Source | bone marrow stromal cell antigen 2 | 11635 | -0.063 | -0.3963 | Yes |
| 34 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 11718 | -0.065 | -0.3857 | Yes |
| 35 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 11928 | -0.071 | -0.3833 | Yes |
| 36 | TAPBP | TAPBP Entrez, Source | TAP binding protein (tapasin) | 12433 | -0.088 | -0.3986 | Yes |
| 37 | LGALS3BP | LGALS3BP Entrez, Source | lectin, galactoside-binding, soluble, 3 binding protein | 12844 | -0.115 | -0.4001 | Yes |
| 38 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 12964 | -0.127 | -0.3764 | Yes |
| 39 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 13071 | -0.143 | -0.3476 | Yes |
| 40 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13262 | -0.231 | -0.3026 | Yes |
| 41 | RIPK2 | RIPK2 Entrez, Source | receptor-interacting serine-threonine kinase 2 | 13286 | -0.265 | -0.2364 | Yes |
| 42 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13292 | -0.273 | -0.1669 | Yes |
| 43 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 13310 | -0.321 | -0.0857 | Yes |
| 44 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 13315 | -0.343 | 0.0020 | Yes |
