Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | SHEPARD_NEG_REG_OF_CELL_PROLIFERATION |
| Enrichment Score (ES) | -0.3952318 |
| Normalized Enrichment Score (NES) | -1.5201759 |
| Nominal p-value | 0.020449897 |
| FDR q-value | 0.27088568 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PLG | PLG Entrez, Source | plasminogen | 229 | 0.144 | 0.0150 | No |
| 2 | OPRM1 | OPRM1 Entrez, Source | opioid receptor, mu 1 | 297 | 0.136 | 0.0402 | No |
| 3 | ADRA1A | ADRA1A Entrez, Source | adrenergic, alpha-1A-, receptor | 312 | 0.134 | 0.0690 | No |
| 4 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 491 | 0.118 | 0.0820 | No |
| 5 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 677 | 0.105 | 0.0916 | No |
| 6 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 789 | 0.100 | 0.1056 | No |
| 7 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 1287 | 0.081 | 0.0861 | No |
| 8 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 1548 | 0.073 | 0.0829 | No |
| 9 | TNFRSF8 | TNFRSF8 Entrez, Source | tumor necrosis factor receptor superfamily, member 8 | 1748 | 0.069 | 0.0833 | No |
| 10 | SSTR2 | SSTR2 Entrez, Source | somatostatin receptor 2 | 2014 | 0.062 | 0.0772 | No |
| 11 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 2450 | 0.053 | 0.0562 | No |
| 12 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 2635 | 0.049 | 0.0533 | No |
| 13 | BTG3 | BTG3 Entrez, Source | BTG family, member 3 | 2641 | 0.049 | 0.0639 | No |
| 14 | FABP6 | FABP6 Entrez, Source | fatty acid binding protein 6, ileal (gastrotropin) | 2755 | 0.047 | 0.0659 | No |
| 15 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3035 | 0.043 | 0.0543 | No |
| 16 | SSTR4 | SSTR4 Entrez, Source | somatostatin receptor 4 | 3223 | 0.040 | 0.0491 | No |
| 17 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 3296 | 0.038 | 0.0522 | No |
| 18 | HGS | HGS Entrez, Source | hepatocyte growth factor-regulated tyrosine kinase substrate | 3319 | 0.038 | 0.0591 | No |
| 19 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 3370 | 0.037 | 0.0636 | No |
| 20 | CDK10 | CDK10 Entrez, Source | cyclin-dependent kinase (CDC2-like) 10 | 4695 | 0.020 | -0.0318 | No |
| 21 | TOB2 | TOB2 Entrez, Source | transducer of ERBB2, 2 | 4866 | 0.018 | -0.0406 | No |
| 22 | GNRH1 | GNRH1 Entrez, Source | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) | 4906 | 0.017 | -0.0397 | No |
| 23 | NF2 | NF2 Entrez, Source | neurofibromin 2 (bilateral acoustic neuroma) | 5026 | 0.016 | -0.0452 | No |
| 24 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 5438 | 0.011 | -0.0737 | No |
| 25 | SST | SST Entrez, Source | somatostatin | 5930 | 0.005 | -0.1096 | No |
| 26 | UMOD | UMOD Entrez, Source | uromodulin (uromucoid, Tamm-Horsfall glycoprotein) | 6419 | 0.000 | -0.1463 | No |
| 27 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 6728 | -0.003 | -0.1688 | No |
| 28 | FABP7 | FABP7 Entrez, Source | fatty acid binding protein 7, brain | 6774 | -0.004 | -0.1714 | No |
| 29 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 6812 | -0.004 | -0.1734 | No |
| 30 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 6990 | -0.006 | -0.1855 | No |
| 31 | CNOT8 | CNOT8 Entrez, Source | CCR4-NOT transcription complex, subunit 8 | 7234 | -0.008 | -0.2020 | No |
| 32 | PMP22 | PMP22 Entrez, Source | peripheral myelin protein 22 | 7414 | -0.010 | -0.2133 | No |
| 33 | PTHLH | PTHLH Entrez, Source | parathyroid hormone-like hormone | 7588 | -0.011 | -0.2238 | No |
| 34 | WARS | WARS Entrez, Source | tryptophanyl-tRNA synthetase | 7827 | -0.014 | -0.2387 | No |
| 35 | MDM4 | MDM4 Entrez, Source | Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse) | 8141 | -0.017 | -0.2585 | No |
| 36 | VHL | VHL Entrez, Source | von Hippel-Lindau tumor suppressor | 8209 | -0.018 | -0.2596 | No |
| 37 | CGRRF1 | CGRRF1 Entrez, Source | cell growth regulator with ring finger domain 1 | 8388 | -0.020 | -0.2686 | No |
| 38 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 8916 | -0.025 | -0.3027 | No |
| 39 | AIF1 | AIF1 Entrez, Source | allograft inflammatory factor 1 | 9000 | -0.026 | -0.3032 | No |
| 40 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 9056 | -0.027 | -0.3014 | No |
| 41 | FABP3 | FABP3 Entrez, Source | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | 9059 | -0.027 | -0.2956 | No |
| 42 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 9542 | -0.032 | -0.3248 | No |
| 43 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 9619 | -0.033 | -0.3231 | No |
| 44 | IGFBP6 | IGFBP6 Entrez, Source | insulin-like growth factor binding protein 6 | 9677 | -0.034 | -0.3199 | No |
| 45 | SSTR5 | SSTR5 Entrez, Source | somatostatin receptor 5 | 9703 | -0.034 | -0.3142 | No |
| 46 | ING1 | ING1 Entrez, Source | inhibitor of growth family, member 1 | 10251 | -0.040 | -0.3464 | No |
| 47 | SSTR1 | SSTR1 Entrez, Source | somatostatin receptor 1 | 10304 | -0.041 | -0.3413 | No |
| 48 | CTBP1 | CTBP1 Entrez, Source | C-terminal binding protein 1 | 10344 | -0.041 | -0.3351 | No |
| 49 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 10357 | -0.041 | -0.3267 | No |
| 50 | NDN | NDN Entrez, Source | necdin homolog (mouse) | 10375 | -0.042 | -0.3187 | No |
| 51 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 10678 | -0.046 | -0.3313 | No |
| 52 | POU1F1 | POU1F1 Entrez, Source | POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1) | 10759 | -0.047 | -0.3267 | No |
| 53 | PCAF | PCAF Entrez, Source | p300/CBP-associated factor | 11315 | -0.057 | -0.3558 | No |
| 54 | QSCN6 | QSCN6 Entrez, Source | quiescin Q6 | 11386 | -0.058 | -0.3480 | No |
| 55 | CUL5 | CUL5 Entrez, Source | cullin 5 | 11698 | -0.065 | -0.3570 | No |
| 56 | IL1B | IL1B Entrez, Source | interleukin 1, beta | 12206 | -0.080 | -0.3775 | Yes |
| 57 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 12350 | -0.085 | -0.3692 | Yes |
| 58 | COL18A1 | COL18A1 Entrez, Source | collagen, type XVIII, alpha 1 | 12394 | -0.087 | -0.3531 | Yes |
| 59 | CGREF1 | CGREF1 Entrez, Source | cell growth regulator with EF-hand domain 1 | 12621 | -0.098 | -0.3483 | Yes |
| 60 | PRKRA | PRKRA Entrez, Source | protein kinase, interferon-inducible double stranded RNA dependent activator | 12674 | -0.101 | -0.3297 | Yes |
| 61 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 12814 | -0.112 | -0.3153 | Yes |
| 62 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 12847 | -0.115 | -0.2921 | Yes |
| 63 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 12854 | -0.115 | -0.2668 | Yes |
| 64 | PAWR | PAWR Entrez, Source | PRKC, apoptosis, WT1, regulator | 12871 | -0.118 | -0.2417 | Yes |
| 65 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 12901 | -0.121 | -0.2168 | Yes |
| 66 | ETS1 | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 13097 | -0.150 | -0.1980 | Yes |
| 67 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 13140 | -0.159 | -0.1657 | Yes |
| 68 | ADAMTS1 | ADAMTS1 Entrez, Source | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 13169 | -0.170 | -0.1299 | Yes |
| 69 | FRK | FRK Entrez, Source | fyn-related kinase | 13199 | -0.189 | -0.0900 | Yes |
| 70 | IL1A | IL1A Entrez, Source | interleukin 1, alpha | 13241 | -0.218 | -0.0445 | Yes |
| 71 | TM4SF4 | TM4SF4 Entrez, Source | transmembrane 4 L six family member 4 | 13263 | -0.233 | 0.0060 | Yes |
