Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | STATIN_PATHWAY_PHARMGKB |
| Enrichment Score (ES) | 0.5403085 |
| Normalized Enrichment Score (NES) | 1.4954414 |
| Nominal p-value | 0.051282052 |
| FDR q-value | 0.2729416 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HMGCR | HMGCR Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 250 | 0.141 | 0.1314 | Yes |
| 2 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 446 | 0.122 | 0.2464 | Yes |
| 3 | APOA1 | APOA1 Entrez, Source | apolipoprotein A-I | 552 | 0.113 | 0.3590 | Yes |
| 4 | LPL | LPL Entrez, Source | lipoprotein lipase | 1116 | 0.087 | 0.4089 | Yes |
| 5 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 1832 | 0.067 | 0.4262 | Yes |
| 6 | LCAT | LCAT Entrez, Source | lecithin-cholesterol acyltransferase | 2089 | 0.060 | 0.4710 | Yes |
| 7 | CYP7A1 | CYP7A1 Entrez, Source | cytochrome P450, family 7, subfamily A, polypeptide 1 | 2589 | 0.050 | 0.4866 | Yes |
| 8 | APOC1 | APOC1 Entrez, Source | apolipoprotein C-I | 2829 | 0.046 | 0.5173 | Yes |
| 9 | LDLR | LDLR Entrez, Source | low density lipoprotein receptor (familial hypercholesterolemia) | 3110 | 0.041 | 0.5403 | Yes |
| 10 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 3594 | 0.034 | 0.5401 | No |
| 11 | APOC3 | APOC3 Entrez, Source | apolipoprotein C-III | 4715 | 0.019 | 0.4768 | No |
| 12 | APOE | APOE Entrez, Source | apolipoprotein E | 7282 | -0.008 | 0.2932 | No |
| 13 | APOA4 | APOA4 Entrez, Source | apolipoprotein A-IV | 7392 | -0.009 | 0.2950 | No |
| 14 | DGAT1 | DGAT1 Entrez, Source | diacylglycerol O-acyltransferase homolog 1 (mouse) | 9852 | -0.036 | 0.1484 | No |
| 15 | LIPC | LIPC Entrez, Source | lipase, hepatic | 10652 | -0.046 | 0.1368 | No |
| 16 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 11542 | -0.061 | 0.1351 | No |
