Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | STEMCELL_COMMON_UP |
| Enrichment Score (ES) | -0.3633243 |
| Normalized Enrichment Score (NES) | -1.4724803 |
| Nominal p-value | 0.018108651 |
| FDR q-value | 0.2923888 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 491 | 0.118 | -0.0058 | No |
| 2 | RNF138 | RNF138 Entrez, Source | ring finger protein 138 | 1949 | 0.064 | -0.0990 | No |
| 3 | RCL1 | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 2305 | 0.055 | -0.1113 | No |
| 4 | ZCCHC10 | ZCCHC10 Entrez, Source | zinc finger, CCHC domain containing 10 | 2633 | 0.049 | -0.1229 | No |
| 5 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 2635 | 0.049 | -0.1100 | No |
| 6 | GNL2 | GNL2 Entrez, Source | guanine nucleotide binding protein-like 2 (nucleolar) | 2742 | 0.047 | -0.1056 | No |
| 7 | SLC38A2 | SLC38A2 Entrez, Source | solute carrier family 38, member 2 | 2830 | 0.046 | -0.1001 | No |
| 8 | DNAJB6 | DNAJB6 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 6 | 2973 | 0.043 | -0.0993 | No |
| 9 | FHL1 | FHL1 Entrez, Source | four and a half LIM domains 1 | 2980 | 0.043 | -0.0883 | No |
| 10 | EIF4G2 | EIF4G2 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 2 | 3103 | 0.042 | -0.0866 | No |
| 11 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 3200 | 0.040 | -0.0833 | No |
| 12 | MARCH7 | MARCH7 Entrez, Source | membrane-associated ring finger (C3HC4) 7 | 3217 | 0.040 | -0.0740 | No |
| 13 | TBRG4 | TBRG4 Entrez, Source | transforming growth factor beta regulator 4 | 3500 | 0.035 | -0.0860 | No |
| 14 | KCNAB3 | KCNAB3 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, beta member 3 | 3756 | 0.032 | -0.0968 | No |
| 15 | UBE2D2 | UBE2D2 Entrez, Source | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | 3952 | 0.029 | -0.1039 | No |
| 16 | ELOVL6 | ELOVL6 Entrez, Source | ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4158 | 0.026 | -0.1124 | No |
| 17 | PDCD2 | PDCD2 Entrez, Source | programmed cell death 2 | 4230 | 0.026 | -0.1110 | No |
| 18 | ARCN1 | ARCN1 Entrez, Source | archain 1 | 4483 | 0.022 | -0.1242 | No |
| 19 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 4604 | 0.021 | -0.1278 | No |
| 20 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 4664 | 0.020 | -0.1270 | No |
| 21 | SEC23IP | SEC23IP Entrez, Source | SEC23 interacting protein | 4743 | 0.019 | -0.1279 | No |
| 22 | ZMAT3 | ZMAT3 Entrez, Source | zinc finger, matrin type 3 | 4879 | 0.018 | -0.1334 | No |
| 23 | CIRH1A | CIRH1A Entrez, Source | cirrhosis, autosomal recessive 1A (cirhin) | 5008 | 0.016 | -0.1388 | No |
| 24 | RABGGTB | RABGGTB Entrez, Source | Rab geranylgeranyltransferase, beta subunit | 5146 | 0.014 | -0.1454 | No |
| 25 | FBXO8 | FBXO8 Entrez, Source | F-box protein 8 | 5185 | 0.014 | -0.1446 | No |
| 26 | RNF4 | RNF4 Entrez, Source | ring finger protein 4 | 5355 | 0.012 | -0.1542 | No |
| 27 | RAD23B | RAD23B Entrez, Source | RAD23 homolog B (S. cerevisiae) | 5366 | 0.012 | -0.1519 | No |
| 28 | DPH5 | DPH5 Entrez, Source | DPH5 homolog (S. cerevisiae) | 5403 | 0.011 | -0.1516 | No |
| 29 | MKI67IP | MKI67IP Entrez, Source | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 5611 | 0.009 | -0.1649 | No |
| 30 | NUP35 | NUP35 Entrez, Source | nucleoporin 35kDa | 5971 | 0.005 | -0.1907 | No |
| 31 | TXNL1 | TXNL1 Entrez, Source | thioredoxin-like 1 | 6029 | 0.004 | -0.1938 | No |
| 32 | PRPSAP1 | PRPSAP1 Entrez, Source | phosphoribosyl pyrophosphate synthetase-associated protein 1 | 6235 | 0.002 | -0.2088 | No |
| 33 | FKBP11 | FKBP11 Entrez, Source | FK506 binding protein 11, 19 kDa | 6274 | 0.002 | -0.2113 | No |
| 34 | TBC1D15 | TBC1D15 Entrez, Source | TBC1 domain family, member 15 | 6334 | 0.001 | -0.2155 | No |
| 35 | USP10 | USP10 Entrez, Source | ubiquitin specific peptidase 10 | 6609 | -0.002 | -0.2356 | No |
| 36 | GRWD1 | GRWD1 Entrez, Source | glutamate-rich WD repeat containing 1 | 6710 | -0.003 | -0.2424 | No |
| 37 | MTERFD1 | MTERFD1 Entrez, Source | MTERF domain containing 1 | 6808 | -0.004 | -0.2487 | No |
| 38 | GCLM | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 6879 | -0.004 | -0.2528 | No |
| 39 | PPP1R2 | PPP1R2 Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 6926 | -0.005 | -0.2550 | No |
| 40 | PLA2G6 | PLA2G6 Entrez, Source | phospholipase A2, group VI (cytosolic, calcium-independent) | 6933 | -0.005 | -0.2542 | No |
| 41 | RPS6KB1 | RPS6KB1 Entrez, Source | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 7068 | -0.006 | -0.2626 | No |
| 42 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 7116 | -0.007 | -0.2644 | No |
| 43 | PSMD12 | PSMD12 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 7220 | -0.008 | -0.2701 | No |
| 44 | EIF4EBP1 | EIF4EBP1 Entrez, Source | eukaryotic translation initiation factor 4E binding protein 1 | 7338 | -0.009 | -0.2766 | No |
| 45 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 7439 | -0.010 | -0.2815 | No |
| 46 | SMAD1 | SMAD1 Entrez, Source | SMAD, mothers against DPP homolog 1 (Drosophila) | 7489 | -0.010 | -0.2825 | No |
| 47 | RPL22 | RPL22 Entrez, Source | ribosomal protein L22 | 7527 | -0.011 | -0.2824 | No |
| 48 | ARIH1 | ARIH1 Entrez, Source | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) | 7627 | -0.012 | -0.2868 | No |
| 49 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 7656 | -0.012 | -0.2857 | No |
| 50 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 7670 | -0.012 | -0.2835 | No |
| 51 | COPS4 | COPS4 Entrez, Source | COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) | 7721 | -0.013 | -0.2839 | No |
| 52 | GCAT | GCAT Entrez, Source | glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase) | 8259 | -0.018 | -0.3196 | No |
| 53 | RFFL | RFFL Entrez, Source | ring finger and FYVE-like domain containing 1 | 8334 | -0.019 | -0.3202 | No |
| 54 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 8391 | -0.020 | -0.3192 | No |
| 55 | LAPTM4A | LAPTM4A Entrez, Source | lysosomal-associated protein transmembrane 4 alpha | 8485 | -0.021 | -0.3208 | No |
| 56 | LAPTM4B | LAPTM4B Entrez, Source | lysosomal associated protein transmembrane 4 beta | 8548 | -0.021 | -0.3199 | No |
| 57 | PIGX | PIGX Entrez, Source | phosphatidylinositol glycan anchor biosynthesis, class X | 8772 | -0.023 | -0.3306 | No |
| 58 | PLS3 | PLS3 Entrez, Source | plastin 3 (T isoform) | 9132 | -0.027 | -0.3505 | No |
| 59 | YWHAB | YWHAB Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 9164 | -0.028 | -0.3455 | No |
| 60 | MPDU1 | MPDU1 Entrez, Source | mannose-P-dolichol utilization defect 1 | 9201 | -0.028 | -0.3408 | No |
| 61 | FKBP9 | FKBP9 Entrez, Source | FK506 binding protein 9, 63 kDa | 9351 | -0.030 | -0.3442 | No |
| 62 | STATIP1 | STATIP1 Entrez, Source | signal transducer and activator of transcription 3 interacting protein 1 | 9375 | -0.030 | -0.3381 | No |
| 63 | PTPN2 | PTPN2 Entrez, Source | protein tyrosine phosphatase, non-receptor type 2 | 9568 | -0.032 | -0.3441 | No |
| 64 | LSG1 | LSG1 Entrez, Source | large subunit GTPase 1 homolog (S. cerevisiae) | 9662 | -0.033 | -0.3423 | No |
| 65 | CTTN | CTTN Entrez, Source | cortactin | 9710 | -0.034 | -0.3368 | No |
| 66 | UPP1 | UPP1 Entrez, Source | uridine phosphorylase 1 | 10062 | -0.038 | -0.3533 | Yes |
| 67 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 10127 | -0.039 | -0.3480 | Yes |
| 68 | XRCC5 | XRCC5 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) | 10271 | -0.040 | -0.3481 | Yes |
| 69 | KLHL7 | KLHL7 Entrez, Source | kelch-like 7 (Drosophila) | 10280 | -0.040 | -0.3380 | Yes |
| 70 | TPP2 | TPP2 Entrez, Source | tripeptidyl peptidase II | 10285 | -0.040 | -0.3277 | Yes |
| 71 | YWHAH | YWHAH Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 10384 | -0.042 | -0.3241 | Yes |
| 72 | TARSL1 | TARSL1 Entrez, Source | threonyl-tRNA synthetase-like 1 | 10388 | -0.042 | -0.3133 | Yes |
| 73 | MAP4K3 | MAP4K3 Entrez, Source | mitogen-activated protein kinase kinase kinase kinase 3 | 10409 | -0.042 | -0.3037 | Yes |
| 74 | MRPL17 | MRPL17 Entrez, Source | mitochondrial ribosomal protein L17 | 10452 | -0.043 | -0.2957 | Yes |
| 75 | GNB1 | GNB1 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 10542 | -0.044 | -0.2907 | Yes |
| 76 | GSTA4 | GSTA4 Entrez, Source | glutathione S-transferase A4 | 10872 | -0.049 | -0.3026 | Yes |
| 77 | SUCLG2 | SUCLG2 Entrez, Source | succinate-CoA ligase, GDP-forming, beta subunit | 10905 | -0.050 | -0.2919 | Yes |
| 78 | MRPL34 | MRPL34 Entrez, Source | mitochondrial ribosomal protein L34 | 10999 | -0.051 | -0.2855 | Yes |
| 79 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 11016 | -0.051 | -0.2731 | Yes |
| 80 | STRN3 | STRN3 Entrez, Source | striatin, calmodulin binding protein 3 | 11023 | -0.051 | -0.2600 | Yes |
| 81 | IMPAD1 | IMPAD1 Entrez, Source | inositol monophosphatase domain containing 1 | 11213 | -0.055 | -0.2598 | Yes |
| 82 | PEX7 | PEX7 Entrez, Source | peroxisomal biogenesis factor 7 | 11330 | -0.057 | -0.2533 | Yes |
| 83 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 11353 | -0.058 | -0.2397 | Yes |
| 84 | CRSP3 | CRSP3 Entrez, Source | cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa | 11567 | -0.062 | -0.2395 | Yes |
| 85 | DICER1 | DICER1 Entrez, Source | Dicer1, Dcr-1 homolog (Drosophila) | 11587 | -0.062 | -0.2245 | Yes |
| 86 | RYK | RYK Entrez, Source | RYK receptor-like tyrosine kinase | 11696 | -0.065 | -0.2156 | Yes |
| 87 | STXBP3 | STXBP3 Entrez, Source | syntaxin binding protein 3 | 11792 | -0.067 | -0.2051 | Yes |
| 88 | SLC4A7 | SLC4A7 Entrez, Source | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 11826 | -0.068 | -0.1896 | Yes |
| 89 | XTP3TPA | XTP3TPA Entrez, Source | - | 11867 | -0.069 | -0.1744 | Yes |
| 90 | ALDH7A1 | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 12088 | -0.076 | -0.1711 | Yes |
| 91 | TXNDC9 | TXNDC9 Entrez, Source | thioredoxin domain containing 9 | 12236 | -0.081 | -0.1609 | Yes |
| 92 | PANX3 | PANX3 Entrez, Source | pannexin 3 | 12471 | -0.090 | -0.1549 | Yes |
| 93 | RPUSD4 | RPUSD4 Entrez, Source | RNA pseudouridylate synthase domain containing 4 | 12496 | -0.091 | -0.1326 | Yes |
| 94 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 12758 | -0.107 | -0.1239 | Yes |
| 95 | KIF2A | KIF2A Entrez, Source | kinesin heavy chain member 2A | 12962 | -0.127 | -0.1057 | Yes |
| 96 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 13146 | -0.160 | -0.0773 | Yes |
| 97 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 13167 | -0.169 | -0.0342 | Yes |
| 98 | PPIC | PPIC Entrez, Source | peptidylprolyl isomerase C (cyclophilin C) | 13186 | -0.179 | 0.0118 | Yes |
