Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | STEROID_BIOSYNTHETIC_PROCESS |
| Enrichment Score (ES) | 0.63562596 |
| Normalized Enrichment Score (NES) | 1.8322396 |
| Nominal p-value | 0.0038387715 |
| FDR q-value | 0.078303516 |
| FWER p-Value | 0.946 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DHCR24 | DHCR24 Entrez, Source | 24-dehydrocholesterol reductase | 308 | 0.134 | 0.1299 | Yes |
| 2 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 960 | 0.093 | 0.1874 | Yes |
| 3 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 1022 | 0.091 | 0.2862 | Yes |
| 4 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 1770 | 0.068 | 0.3079 | Yes |
| 5 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 1791 | 0.068 | 0.3837 | Yes |
| 6 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 1796 | 0.068 | 0.4605 | Yes |
| 7 | CYP11A1 | CYP11A1 Entrez, Source | cytochrome P450, family 11, subfamily A, polypeptide 1 | 2097 | 0.060 | 0.5065 | Yes |
| 8 | ADM | ADM Entrez, Source | adrenomedullin | 2189 | 0.058 | 0.5656 | Yes |
| 9 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 3039 | 0.042 | 0.5503 | Yes |
| 10 | SCP2 | SCP2 Entrez, Source | sterol carrier protein 2 | 3048 | 0.042 | 0.5980 | Yes |
| 11 | NR0B1 | NR0B1 Entrez, Source | nuclear receptor subfamily 0, group B, member 1 | 3167 | 0.041 | 0.6356 | Yes |
| 12 | NSDHL | NSDHL Entrez, Source | NAD(P) dependent steroid dehydrogenase-like | 4607 | 0.021 | 0.5512 | No |
| 13 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 4655 | 0.020 | 0.5705 | No |
| 14 | CNBP | CNBP Entrez, Source | CCHC-type zinc finger, nucleic acid binding protein | 7098 | -0.007 | 0.3947 | No |
| 15 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7350 | -0.009 | 0.3862 | No |
| 16 | FDXR | FDXR Entrez, Source | ferredoxin reductase | 8198 | -0.018 | 0.3428 | No |
| 17 | DHCR7 | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 8206 | -0.018 | 0.3625 | No |
| 18 | HSD3B7 | HSD3B7 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 8441 | -0.020 | 0.3678 | No |
