Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | STEROID_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.5100983 |
| Normalized Enrichment Score (NES) | 1.7710295 |
| Nominal p-value | 0.0056497175 |
| FDR q-value | 0.093126215 |
| FWER p-Value | 0.993 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NR0B2 | NR0B2 Entrez, Source | nuclear receptor subfamily 0, group B, member 2 | 38 | 0.227 | 0.1084 | Yes |
| 2 | DHCR24 | DHCR24 Entrez, Source | 24-dehydrocholesterol reductase | 308 | 0.134 | 0.1539 | Yes |
| 3 | SULT2A1 | SULT2A1 Entrez, Source | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 367 | 0.128 | 0.2123 | Yes |
| 4 | IL4 | IL4 Entrez, Source | interleukin 4 | 824 | 0.098 | 0.2262 | Yes |
| 5 | NR1I2 | NR1I2 Entrez, Source | nuclear receptor subfamily 1, group I, member 2 | 896 | 0.096 | 0.2677 | Yes |
| 6 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 960 | 0.093 | 0.3085 | Yes |
| 7 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 1022 | 0.091 | 0.3483 | Yes |
| 8 | STS | STS Entrez, Source | steroid sulfatase (microsomal), arylsulfatase C, isozyme S | 1112 | 0.087 | 0.3841 | Yes |
| 9 | AKR1B10 | AKR1B10 Entrez, Source | aldo-keto reductase family 1, member B10 (aldose reductase) | 1279 | 0.081 | 0.4112 | Yes |
| 10 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 1770 | 0.068 | 0.4078 | Yes |
| 11 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 1791 | 0.068 | 0.4394 | Yes |
| 12 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 1796 | 0.068 | 0.4722 | Yes |
| 13 | CYP11A1 | CYP11A1 Entrez, Source | cytochrome P450, family 11, subfamily A, polypeptide 1 | 2097 | 0.060 | 0.4790 | Yes |
| 14 | ADM | ADM Entrez, Source | adrenomedullin | 2189 | 0.058 | 0.5005 | Yes |
| 15 | NR1H4 | NR1H4 Entrez, Source | nuclear receptor subfamily 1, group H, member 4 | 2957 | 0.044 | 0.4642 | Yes |
| 16 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 3039 | 0.042 | 0.4789 | Yes |
| 17 | SCP2 | SCP2 Entrez, Source | sterol carrier protein 2 | 3048 | 0.042 | 0.4990 | Yes |
| 18 | NR0B1 | NR0B1 Entrez, Source | nuclear receptor subfamily 0, group B, member 1 | 3167 | 0.041 | 0.5101 | Yes |
| 19 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 3594 | 0.034 | 0.4947 | No |
| 20 | PPARD | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 3654 | 0.033 | 0.5064 | No |
| 21 | GBA2 | GBA2 Entrez, Source | glucosidase, beta (bile acid) 2 | 4384 | 0.023 | 0.4630 | No |
| 22 | NSDHL | NSDHL Entrez, Source | NAD(P) dependent steroid dehydrogenase-like | 4607 | 0.021 | 0.4564 | No |
| 23 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 4655 | 0.020 | 0.4627 | No |
| 24 | MBTPS2 | MBTPS2 Entrez, Source | membrane-bound transcription factor peptidase, site 2 | 5428 | 0.011 | 0.4100 | No |
| 25 | DHRS9 | DHRS9 Entrez, Source | dehydrogenase/reductase (SDR family) member 9 | 5622 | 0.009 | 0.3998 | No |
| 26 | SHH | SHH Entrez, Source | sonic hedgehog homolog (Drosophila) | 5903 | 0.005 | 0.3815 | No |
| 27 | HDLBP | HDLBP Entrez, Source | high density lipoprotein binding protein (vigilin) | 6097 | 0.004 | 0.3687 | No |
| 28 | STUB1 | STUB1 Entrez, Source | STIP1 homology and U-box containing protein 1 | 6260 | 0.002 | 0.3574 | No |
| 29 | TSPO | TSPO Entrez, Source | translocator protein (18kDa) | 6559 | -0.002 | 0.3358 | No |
| 30 | CLN8 | CLN8 Entrez, Source | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) | 6600 | -0.002 | 0.3337 | No |
| 31 | CNBP | CNBP Entrez, Source | CCHC-type zinc finger, nucleic acid binding protein | 7098 | -0.007 | 0.2996 | No |
| 32 | ACOX3 | ACOX3 Entrez, Source | acyl-Coenzyme A oxidase 3, pristanoyl | 7205 | -0.008 | 0.2954 | No |
| 33 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7350 | -0.009 | 0.2890 | No |
| 34 | FDXR | FDXR Entrez, Source | ferredoxin reductase | 8198 | -0.018 | 0.2339 | No |
| 35 | DHCR7 | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 8206 | -0.018 | 0.2421 | No |
| 36 | HSD3B7 | HSD3B7 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 8441 | -0.020 | 0.2343 | No |
| 37 | ABCG1 | ABCG1 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 1 | 8730 | -0.023 | 0.2240 | No |
| 38 | CEL | CEL Entrez, Source | carboxyl ester lipase (bile salt-stimulated lipase) | 9883 | -0.036 | 0.1550 | No |
| 39 | YWHAH | YWHAH Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 10384 | -0.042 | 0.1377 | No |
| 40 | ACOX2 | ACOX2 Entrez, Source | acyl-Coenzyme A oxidase 2, branched chain | 10680 | -0.046 | 0.1380 | No |
| 41 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 11542 | -0.061 | 0.1032 | No |
| 42 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 11730 | -0.065 | 0.1212 | No |
