Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | ST_TUMOR_NECROSIS_FACTOR_PATHWAY |
| Enrichment Score (ES) | -0.56779766 |
| Normalized Enrichment Score (NES) | -1.6073185 |
| Nominal p-value | 0.027600849 |
| FDR q-value | 0.23391582 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NFKBIL1 | NFKBIL1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 | 3321 | 0.038 | -0.2047 | No |
| 2 | JUN | JUN Entrez, Source | jun oncogene | 4841 | 0.018 | -0.2975 | No |
| 3 | BIRC2 | BIRC2 Entrez, Source | baculoviral IAP repeat-containing 2 | 5286 | 0.013 | -0.3159 | No |
| 4 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 5475 | 0.010 | -0.3178 | No |
| 5 | NR2C2 | NR2C2 Entrez, Source | nuclear receptor subfamily 2, group C, member 2 | 6755 | -0.003 | -0.4098 | No |
| 6 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 7260 | -0.008 | -0.4380 | No |
| 7 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 7301 | -0.009 | -0.4309 | No |
| 8 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 7416 | -0.010 | -0.4280 | No |
| 9 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 8457 | -0.020 | -0.4823 | No |
| 10 | NFKBIB | NFKBIB Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 8711 | -0.023 | -0.4744 | No |
| 11 | TRADD | TRADD Entrez, Source | TNFRSF1A-associated via death domain | 9040 | -0.026 | -0.4679 | No |
| 12 | BAG4 | BAG4 Entrez, Source | BCL2-associated athanogene 4 | 10207 | -0.040 | -0.5090 | Yes |
| 13 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 10368 | -0.041 | -0.4723 | Yes |
| 14 | RALBP1 | RALBP1 Entrez, Source | ralA binding protein 1 | 11641 | -0.063 | -0.4933 | Yes |
| 15 | CFLAR | CFLAR Entrez, Source | CASP8 and FADD-like apoptosis regulator | 11917 | -0.070 | -0.4316 | Yes |
| 16 | FADD | FADD Entrez, Source | Fas (TNFRSF6)-associated via death domain | 12156 | -0.078 | -0.3581 | Yes |
| 17 | NFKB2 | NFKB2 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 12794 | -0.110 | -0.2767 | Yes |
| 18 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 12964 | -0.127 | -0.1401 | Yes |
| 19 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 13071 | -0.143 | 0.0203 | Yes |
