Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_24h_versus_single_gel_24h.class.cls
#double_gel_24h_versus_single_gel_24h_repos
Phenotypeclass.cls#double_gel_24h_versus_single_gel_24h_repos
Upregulated in classdouble_gel_24h
GeneSetSUBSTRATE_SPECIFIC_TRANSMEMBRANE_TRANSPORTER_ACTIVITY
Enrichment Score (ES)0.3114279
Normalized Enrichment Score (NES)1.4618815
Nominal p-value0.004040404
FDR q-value0.29111186
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: SUBSTRATE_SPECIFIC_TRANSMEMBRANE_TRANSPORTER_ACTIVITY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1SLC10A1SLC10A1
Entrez,  Source
solute carrier family 10 (sodium/bile acid cotransporter family), member 1190.2660.0192Yes
2SLC12A3SLC12A3
Entrez,  Source
solute carrier family 12 (sodium/chloride transporters), member 3770.1880.0294Yes
3CHRNA7CHRNA7
Entrez,  Source
cholinergic receptor, nicotinic, alpha 71070.1750.0407Yes
4AQP9AQP9
Entrez,  Source
aquaporin 92320.1440.0424Yes
5SLC22A1SLC22A1
Entrez,  Source
solute carrier family 22 (organic cation transporter), member 12760.1380.0498Yes
6SLC6A5SLC6A5
Entrez,  Source
solute carrier family 6 (neurotransmitter transporter, glycine), member 54480.1220.0462Yes
7ABCC8ABCC8
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 84720.1200.0537Yes
8KCNB2KCNB2
Entrez,  Source
potassium voltage-gated channel, Shab-related subfamily, member 24830.1190.0622Yes
9KCNJ4KCNJ4
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 45460.1140.0663Yes
10NOX1NOX1
Entrez,  Source
NADPH oxidase 15600.1130.0740Yes
11SLC2A4SLC2A4
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 45620.1130.0827Yes
12ATP2B4ATP2B4
Entrez,  Source
ATPase, Ca++ transporting, plasma membrane 46200.1090.0868Yes
13SLC16A6SLC16A6
Entrez,  Source
solute carrier family 16, member 6 (monocarboxylic acid transporter 7)6740.1050.0909Yes
14SCN2BSCN2B
Entrez,  Source
sodium channel, voltage-gated, type II, beta6890.1050.0980Yes
15CACNG2CACNG2
Entrez,  Source
calcium channel, voltage-dependent, gamma subunit 26930.1040.1058Yes
16CLCNKBCLCNKB
Entrez,  Source
chloride channel Kb7100.1040.1126Yes
17CLCN1CLCN1
Entrez,  Source
chloride channel 1, skeletal muscle (Thomsen disease, autosomal dominant)7150.1030.1203Yes
18SLC6A2SLC6A2
Entrez,  Source
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 27600.1010.1248Yes
19SLC19A2SLC19A2
Entrez,  Source
solute carrier family 19 (thiamine transporter), member 28780.0960.1233Yes
20TRPV5TRPV5
Entrez,  Source
transient receptor potential cation channel, subfamily V, member 59030.0950.1289Yes
21RYR2RYR2
Entrez,  Source
ryanodine receptor 2 (cardiac)9170.0950.1352Yes
22KCNJ14KCNJ14
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 149360.0940.1412Yes
23SLC2A5SLC2A5
Entrez,  Source
solute carrier family 2 (facilitated glucose/fructose transporter), member 59740.0920.1455Yes
24SLC1A3SLC1A3
Entrez,  Source
solute carrier family 1 (glial high affinity glutamate transporter), member 39840.0920.1519Yes
25CHRNA3CHRNA3
Entrez,  Source
cholinergic receptor, nicotinic, alpha 39920.0920.1585Yes
26SLC15A2SLC15A2
Entrez,  Source
solute carrier family 15 (H+/peptide transporter), member 210070.0910.1645Yes
27KCNN3KCNN3
Entrez,  Source
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 310400.0900.1690Yes
28CACNA2D1CACNA2D1
Entrez,  Source
calcium channel, voltage-dependent, alpha 2/delta subunit 110540.0890.1749Yes
29SLC20A1SLC20A1
Entrez,  Source
solute carrier family 20 (phosphate transporter), member 110650.0890.1810Yes
30ATP2A1ATP2A1
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, fast twitch 110720.0880.1874Yes
31KCNJ6KCNJ6
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 611020.0870.1920Yes
32SLC12A2SLC12A2
Entrez,  Source
solute carrier family 12 (sodium/potassium/chloride transporters), member 211140.0870.1978Yes
33SLC34A1SLC34A1
Entrez,  Source
solute carrier family 34 (sodium phosphate), member 111200.0870.2042Yes
34SLC25A22SLC25A22
Entrez,  Source
solute carrier family 25 (mitochondrial carrier: glutamate), member 2211390.0860.2095Yes
35SLC5A7SLC5A7
Entrez,  Source
solute carrier family 5 (choline transporter), member 711830.0840.2127Yes
36SLC13A2SLC13A2
Entrez,  Source
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 211930.0840.2185Yes
37P2RX1P2RX1
Entrez,  Source
purinergic receptor P2X, ligand-gated ion channel, 112000.0840.2246Yes
38SLC16A1SLC16A1
Entrez,  Source
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)12290.0830.2288Yes
39ACCN1ACCN1
Entrez,  Source
amiloride-sensitive cation channel 1, neuronal (degenerin)13060.0800.2292Yes
40TRPC3TRPC3
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 313520.0790.2319Yes
41SLC1A1SLC1A1
Entrez,  Source
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 114530.0760.2301Yes
42P2RX7P2RX7
Entrez,  Source
purinergic receptor P2X, ligand-gated ion channel, 715000.0750.2324Yes
43TRPV2TRPV2
Entrez,  Source
transient receptor potential cation channel, subfamily V, member 216340.0720.2278Yes
44CACNA1HCACNA1H
Entrez,  Source
calcium channel, voltage-dependent, alpha 1H subunit17370.0690.2253Yes
45SCNN1GSCNN1G
Entrez,  Source
sodium channel, nonvoltage-gated 1, gamma17420.0690.2303Yes
46SLC29A1SLC29A1
Entrez,  Source
solute carrier family 29 (nucleoside transporters), member 117500.0690.2351Yes
47SLC5A2SLC5A2
Entrez,  Source
solute carrier family 5 (sodium/glucose cotransporter), member 217970.0680.2368Yes
48SLC37A4SLC37A4
Entrez,  Source
solute carrier family 37 (glycerol-6-phosphate transporter), member 418180.0670.2405Yes
49ATP2A3ATP2A3
Entrez,  Source
ATPase, Ca++ transporting, ubiquitous19120.0640.2384Yes
50CACNA1CCACNA1C
Entrez,  Source
calcium channel, voltage-dependent, L type, alpha 1C subunit19390.0640.2413Yes
51CFTRCFTR
Entrez,  Source
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)19460.0640.2458Yes
52SLC30A3SLC30A3
Entrez,  Source
solute carrier family 30 (zinc transporter), member 319630.0630.2495Yes
53SCN4BSCN4B
Entrez,  Source
sodium channel, voltage-gated, type IV, beta19650.0630.2543Yes
54ATP4AATP4A
Entrez,  Source
ATPase, H+/K+ exchanging, alpha polypeptide20130.0620.2556Yes
55COX4I2COX4I2
Entrez,  Source
cytochrome c oxidase subunit IV isoform 2 (lung)20910.0600.2543Yes
56CHRNB2CHRNB2
Entrez,  Source
cholinergic receptor, nicotinic, beta 2 (neuronal)21010.0600.2583Yes
57KCNK3KCNK3
Entrez,  Source
potassium channel, subfamily K, member 321320.0590.2606Yes
58ITPR3ITPR3
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 322510.0560.2559Yes
59SCNN1BSCNN1B
Entrez,  Source
sodium channel, nonvoltage-gated 1, beta (Liddle syndrome)22670.0560.2591Yes
60SLC16A8SLC16A8
Entrez,  Source
solute carrier family 16, member 8 (monocarboxylic acid transporter 3)24180.0530.2518Yes
61SLC3A1SLC3A1
Entrez,  Source
124220.0530.2557Yes
62SLC5A1SLC5A1
Entrez,  Source
solute carrier family 5 (sodium/glucose cotransporter), member 124330.0530.2590Yes
63CACNA1SCACNA1S
Entrez,  Source
calcium channel, voltage-dependent, L type, alpha 1S subunit24400.0530.2627Yes
64RHCGRHCG
Entrez,  Source
Rh family, C glycoprotein24520.0530.2659Yes
65TRPV1TRPV1
Entrez,  Source
transient receptor potential cation channel, subfamily V, member 124780.0520.2680Yes
66CACNB3CACNB3
Entrez,  Source
calcium channel, voltage-dependent, beta 3 subunit25380.0510.2675Yes
67CACNA1ECACNA1E
Entrez,  Source
calcium channel, voltage-dependent, alpha 1E subunit25450.0510.2709Yes
68SLC1A2SLC1A2
Entrez,  Source
solute carrier family 1 (glial high affinity glutamate transporter), member 225580.0510.2739Yes
69ATP1A3ATP1A3
Entrez,  Source
ATPase, Na+/K+ transporting, alpha 3 polypeptide25600.0500.2778Yes
70KCNH3KCNH3
Entrez,  Source
potassium voltage-gated channel, subfamily H (eag-related), member 325610.0500.2817Yes
71BSNDBSND
Entrez,  Source
Bartter syndrome, infantile, with sensorineural deafness (Barttin)25930.0500.2832Yes
72SLC9A1SLC9A1
Entrez,  Source
solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive)26060.0500.2861Yes
73MS4A2MS4A2
Entrez,  Source
membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)26080.0500.2899Yes
74KCNH4KCNH4
Entrez,  Source
potassium voltage-gated channel, subfamily H (eag-related), member 426280.0490.2922Yes
75KCNMB1KCNMB1
Entrez,  Source
potassium large conductance calcium-activated channel, subfamily M, beta member 126720.0490.2927Yes
76KCNK15KCNK15
Entrez,  Source
potassium channel, subfamily K, member 1527260.0480.2923Yes
77SLC7A10SLC7A10
Entrez,  Source
solute carrier family 7, (neutral amino acid transporter, y+ system) member 1028830.0450.2839Yes
78SLC26A4SLC26A4
Entrez,  Source
solute carrier family 26, member 428920.0450.2867Yes
79ATP7AATP7A
Entrez,  Source
ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome)29700.0430.2842Yes
80SLC12A1SLC12A1
Entrez,  Source
solute carrier family 12 (sodium/potassium/chloride transporters), member 129830.0430.2866Yes
81SLC9A2SLC9A2
Entrez,  Source
solute carrier family 9 (sodium/hydrogen exchanger), member 230800.0420.2825Yes
82SLC1A6SLC1A6
Entrez,  Source
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 630850.0420.2855Yes
83SLC22A7SLC22A7
Entrez,  Source
solute carrier family 22 (organic anion transporter), member 731010.0420.2875Yes
84CACNA1DCACNA1D
Entrez,  Source
calcium channel, voltage-dependent, L type, alpha 1D subunit31220.0410.2892Yes
85RHAGRHAG
Entrez,  Source
Rh-associated glycoprotein31230.0410.2924Yes
86ATP4BATP4B
Entrez,  Source
ATPase, H+/K+ exchanging, beta polypeptide31650.0410.2924Yes
87SLC35B1SLC35B1
Entrez,  Source
solute carrier family 35, member B131760.0400.2948Yes
88CACNG5CACNG5
Entrez,  Source
calcium channel, voltage-dependent, gamma subunit 532030.0400.2959Yes
89KCNK10KCNK10
Entrez,  Source
potassium channel, subfamily K, member 1032390.0400.2963Yes
90KCNA2KCNA2
Entrez,  Source
potassium voltage-gated channel, shaker-related subfamily, member 232510.0390.2985Yes
91KCNH2KCNH2
Entrez,  Source
potassium voltage-gated channel, subfamily H (eag-related), member 232570.0390.3011Yes
92CNGA3CNGA3
Entrez,  Source
cyclic nucleotide gated channel alpha 333050.0380.3005Yes
93KCNS1KCNS1
Entrez,  Source
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 133240.0380.3021Yes
94KCNK1KCNK1
Entrez,  Source
potassium channel, subfamily K, member 133450.0370.3035Yes
95SLC22A12SLC22A12
Entrez,  Source
solute carrier family 22 (organic anion/cation transporter), member 1233990.0370.3022Yes
96SLC7A8SLC7A8
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 834680.0360.2998Yes
97KCNN4KCNN4
Entrez,  Source
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 434820.0350.3015Yes
98PPBPPPBP
Entrez,  Source
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)35110.0350.3021Yes
99CACNA1ACACNA1A
Entrez,  Source
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit35700.0340.3003Yes
100SLC6A9SLC6A9
Entrez,  Source
solute carrier family 6 (neurotransmitter transporter, glycine), member 935810.0340.3022Yes
101SLC34A3SLC34A3
Entrez,  Source
solute carrier family 34 (sodium phosphate), member 336190.0330.3020Yes
102KCNE2KCNE2
Entrez,  Source
potassium voltage-gated channel, Isk-related family, member 236690.0330.3008Yes
103SLC38A3SLC38A3
Entrez,  Source
solute carrier family 38, member 337280.0320.2988Yes
104SCN5ASCN5A
Entrez,  Source
sodium channel, voltage-gated, type V, alpha (long QT syndrome 3)37750.0320.2978Yes
105TRPM1TRPM1
Entrez,  Source
transient receptor potential cation channel, subfamily M, member 137840.0310.2996Yes
106KCNC3KCNC3
Entrez,  Source
potassium voltage-gated channel, Shaw-related subfamily, member 337880.0310.3018Yes
107KCND3KCND3
Entrez,  Source
potassium voltage-gated channel, Shal-related subfamily, member 338130.0310.3023Yes
108SCN7ASCN7A
Entrez,  Source
sodium channel, voltage-gated, type VII, alpha38510.0300.3019Yes
109KCNA1KCNA1
Entrez,  Source
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)38530.0300.3041Yes
110SLC29A2SLC29A2
Entrez,  Source
solute carrier family 29 (nucleoside transporters), member 238740.0300.3049Yes
111KCNA6KCNA6
Entrez,  Source
potassium voltage-gated channel, shaker-related subfamily, member 638920.0300.3059Yes
112KCNA5KCNA5
Entrez,  Source
potassium voltage-gated channel, shaker-related subfamily, member 539110.0300.3068Yes
113CACNG1CACNG1
Entrez,  Source
calcium channel, voltage-dependent, gamma subunit 139250.0290.3081Yes
114CACNA1GCACNA1G
Entrez,  Source
calcium channel, voltage-dependent, alpha 1G subunit39370.0290.3096Yes
115CLDN16CLDN16
Entrez,  Source
claudin 1640010.0280.3069Yes
116CHRNA6CHRNA6
Entrez,  Source
cholinergic receptor, nicotinic, alpha 640140.0280.3082Yes
117SLC23A2SLC23A2
Entrez,  Source
solute carrier family 23 (nucleobase transporters), member 240320.0280.3091Yes
118SLC4A1SLC4A1
Entrez,  Source
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)40490.0280.3100Yes
119KCNMB4KCNMB4
Entrez,  Source
potassium large conductance calcium-activated channel, subfamily M, beta member 440590.0280.3114Yes
120KCNQ2KCNQ2
Entrez,  Source
potassium voltage-gated channel, KQT-like subfamily, member 241510.0260.3065No
121TRPC5TRPC5
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 543280.0240.2949No
122GLRA1GLRA1
Entrez,  Source
glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)43300.0240.2967No
123FXYD3FXYD3
Entrez,  Source
FXYD domain containing ion transport regulator 343670.0240.2958No
124FXYD1FXYD1
Entrez,  Source
FXYD domain containing ion transport regulator 1 (phospholemman)45020.0220.2872No
125SLC22A6SLC22A6
Entrez,  Source
solute carrier family 22 (organic anion transporter), member 645100.0220.2884No
126CHRNA2CHRNA2
Entrez,  Source
cholinergic receptor, nicotinic, alpha 2 (neuronal)45150.0220.2897No
127P2RX3P2RX3
Entrez,  Source
purinergic receptor P2X, ligand-gated ion channel, 345440.0210.2893No
128SLC22A3SLC22A3
Entrez,  Source
solute carrier family 22 (extraneuronal monoamine transporter), member 345770.0210.2884No
129SLC17A7SLC17A7
Entrez,  Source
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 745960.0210.2887No
130ACCN4ACCN4
Entrez,  Source
amiloride-sensitive cation channel 4, pituitary46300.0200.2877No
131SLC14A2SLC14A2
Entrez,  Source
solute carrier family 14 (urea transporter), member 246400.0200.2886No
132TRPC4TRPC4
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 447220.0190.2839No
133HTR3AHTR3A
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 3A47850.0190.2806No
134KCNJ3KCNJ3
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 347920.0190.2816No
135SLC7A5SLC7A5
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 548030.0180.2822No
136KCNH1KCNH1
Entrez,  Source
potassium voltage-gated channel, subfamily H (eag-related), member 148300.0180.2817No
137GLRA2GLRA2
Entrez,  Source
glycine receptor, alpha 248350.0180.2828No
138KCNA3KCNA3
Entrez,  Source
potassium voltage-gated channel, shaker-related subfamily, member 348440.0180.2835No
139ATP6V0CATP6V0C
Entrez,  Source
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c49000.0170.2807No
140GJA1GJA1
Entrez,  Source
gap junction protein, alpha 1, 43kDa (connexin 43)49020.0170.2819No
141SLC9A3SLC9A3
Entrez,  Source
solute carrier family 9 (sodium/hydrogen exchanger), member 349540.0160.2793No
142KCNQ3KCNQ3
Entrez,  Source
potassium voltage-gated channel, KQT-like subfamily, member 349900.0160.2779No
143ATP6V1B2ATP6V1B2
Entrez,  Source
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B250110.0160.2776No
144KCNS3KCNS3
Entrez,  Source
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 351740.0140.2663No
145SERINC1SERINC1
Entrez,  Source
serine incorporator 152710.0130.2599No
146SLC4A2SLC4A2
Entrez,  Source
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)52910.0130.2595No
147KCNA4KCNA4
Entrez,  Source
potassium voltage-gated channel, shaker-related subfamily, member 452990.0130.2599No
148NMUR2NMUR2
Entrez,  Source
neuromedin U receptor 253670.0120.2557No
149SCN11ASCN11A
Entrez,  Source
sodium channel, voltage-gated, type XI, alpha53990.0110.2542No
150CACNG4CACNG4
Entrez,  Source
calcium channel, voltage-dependent, gamma subunit 454840.0100.2486No
151SLC2A3SLC2A3
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 354880.0100.2491No
152COX8ACOX8A
Entrez,  Source
cytochrome c oxidase subunit 8A (ubiquitous)55050.0100.2487No
153SLC11A2SLC11A2
Entrez,  Source
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 255230.0100.2482No
154ITPR2ITPR2
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 255330.0100.2483No
155SCN4ASCN4A
Entrez,  Source
sodium channel, voltage-gated, type IV, alpha55670.0090.2465No
156RYR1RYR1
Entrez,  Source
ryanodine receptor 1 (skeletal)55890.0090.2456No
157PDPNPDPN
Entrez,  Source
podoplanin56030.0090.2453No
158SLC4A3SLC4A3
Entrez,  Source
solute carrier family 4, anion exchanger, member 357180.0080.2371No
159SLC4A4SLC4A4
Entrez,  Source
solute carrier family 4, sodium bicarbonate cotransporter, member 457470.0070.2356No
160MCL1MCL1
Entrez,  Source
myeloid cell leukemia sequence 1 (BCL2-related)58390.0060.2291No
161CLCN2CLCN2
Entrez,  Source
chloride channel 258470.0060.2290No
162KCNIP2KCNIP2
Entrez,  Source
Kv channel interacting protein 258980.0060.2256No
163SLC14A1SLC14A1
Entrez,  Source
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)59010.0050.2259No
164CHRNA4CHRNA4
Entrez,  Source
cholinergic receptor, nicotinic, alpha 459060.0050.2260No
165SLC25A1SLC25A1
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 159380.0050.2240No
166KCNJ15KCNJ15
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 1560030.0050.2195No
167SLC12A9SLC12A9
Entrez,  Source
solute carrier family 12 (potassium/chloride transporters), member 960070.0040.2196No
168KCNE1KCNE1
Entrez,  Source
potassium voltage-gated channel, Isk-related family, member 160530.0040.2165No
169P2RX2P2RX2
Entrez,  Source
purinergic receptor P2X, ligand-gated ion channel, 261390.0030.2102No
170ABCB11ABCB11
Entrez,  Source
ATP-binding cassette, sub-family B (MDR/TAP), member 1161470.0030.2099No
171SCN9ASCN9A
Entrez,  Source
sodium channel, voltage-gated, type IX, alpha61770.0030.2079No
172KCNG2KCNG2
Entrez,  Source
potassium voltage-gated channel, subfamily G, member 262060.0020.2060No
173ATP1B3ATP1B3
Entrez,  Source
ATPase, Na+/K+ transporting, beta 3 polypeptide62380.0020.2037No
174SLC2A1SLC2A1
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 162420.0020.2037No
175ATP6V1C1ATP6V1C1
Entrez,  Source
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C163430.0010.1961No
176SLC9A5SLC9A5
Entrez,  Source
solute carrier family 9 (sodium/hydrogen exchanger), member 563840.0000.1930No
177KCNJ5KCNJ5
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 56426-0.0000.1899No
178SCN1BSCN1B
Entrez,  Source
sodium channel, voltage-gated, type I, beta6455-0.0000.1878No
179CACNB2CACNB2
Entrez,  Source
calcium channel, voltage-dependent, beta 2 subunit6462-0.0000.1874No
180CACNA1BCACNA1B
Entrez,  Source
calcium channel, voltage-dependent, L type, alpha 1B subunit6647-0.0020.1735No
181SLC25A5SLC25A5
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 56656-0.0030.1731No
182COX7BCOX7B
Entrez,  Source
cytochrome c oxidase subunit VIIb6745-0.0030.1666No
183CHRNECHRNE
Entrez,  Source
cholinergic receptor, nicotinic, epsilon6825-0.0040.1609No
184KCNC1KCNC1
Entrez,  Source
potassium voltage-gated channel, Shaw-related subfamily, member 16848-0.0040.1595No
185KCNQ1KCNQ1
Entrez,  Source
potassium voltage-gated channel, KQT-like subfamily, member 16895-0.0050.1563No
186COX5BCOX5B
Entrez,  Source
cytochrome c oxidase subunit Vb6905-0.0050.1560No
187ATP2A2ATP2A2
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, slow twitch 27144-0.0070.1383No
188CCSCCS
Entrez,  Source
copper chaperone for superoxide dismutase7212-0.0080.1338No
189CHRNB4CHRNB4
Entrez,  Source
cholinergic receptor, nicotinic, beta 47214-0.0080.1343No
190SLC3A2SLC3A2
Entrez,  Source
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 27310-0.0090.1277No
191SLC30A4SLC30A4
Entrez,  Source
solute carrier family 30 (zinc transporter), member 47417-0.0100.1204No
192COX4I1COX4I1
Entrez,  Source
cytochrome c oxidase subunit IV isoform 17428-0.0100.1204No
193CHRNDCHRND
Entrez,  Source
cholinergic receptor, nicotinic, delta7510-0.0110.1150No
194CACNB4CACNB4
Entrez,  Source
calcium channel, voltage-dependent, beta 4 subunit7521-0.0110.1151No
195SLC5A5SLC5A5
Entrez,  Source
solute carrier family 5 (sodium iodide symporter), member 57540-0.0110.1145No
196CHRNA1CHRNA1
Entrez,  Source
cholinergic receptor, nicotinic, alpha 1 (muscle)7580-0.0110.1124No
197KCNJ10KCNJ10
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 107799-0.0140.0968No
198UQCRC1UQCRC1
Entrez,  Source
ubiquinol-cytochrome c reductase core protein I7835-0.0140.0952No
199ATP1B2ATP1B2
Entrez,  Source
ATPase, Na+/K+ transporting, beta 2 polypeptide7858-0.0140.0946No
200CNGB1CNGB1
Entrez,  Source
cyclic nucleotide gated channel beta 17881-0.0140.0940No
201ATP2B3ATP2B3
Entrez,  Source
ATPase, Ca++ transporting, plasma membrane 37917-0.0150.0925No
202SLC23A1SLC23A1
Entrez,  Source
solute carrier family 23 (nucleobase transporters), member 17942-0.0150.0918No
203ATP1A2ATP1A2
Entrez,  Source
ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide7997-0.0160.0889No
204CHRNB3CHRNB3
Entrez,  Source
cholinergic receptor, nicotinic, beta 38039-0.0160.0870No
205CLCA2CLCA2
Entrez,  Source
chloride channel, calcium activated, family member 28169-0.0170.0785No
206COX5ACOX5A
Entrez,  Source
cytochrome c oxidase subunit Va8218-0.0180.0762No
207ATP7BATP7B
Entrez,  Source
ATPase, Cu++ transporting, beta polypeptide8306-0.0190.0710No
208KCNJ1KCNJ1
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 18394-0.0200.0659No
209KCNJ12KCNJ12
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 128416-0.0200.0658No
210SLC25A11SLC25A11
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 118440-0.0200.0656No
211SLC6A8SLC6A8
Entrez,  Source
solute carrier family 6 (neurotransmitter transporter, creatine), member 88500-0.0210.0627No
212GLRBGLRB
Entrez,  Source
glycine receptor, beta8597-0.0220.0570No
213AQP7AQP7
Entrez,  Source
aquaporin 78603-0.0220.0583No
214SLC22A2SLC22A2
Entrez,  Source
solute carrier family 22 (organic cation transporter), member 28687-0.0230.0537No
215CACNB1CACNB1
Entrez,  Source
calcium channel, voltage-dependent, beta 1 subunit8689-0.0230.0554No
216UQCRHUQCRH
Entrez,  Source
ubiquinol-cytochrome c reductase hinge protein8723-0.0230.0547No
217ABCC5ABCC5
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 58737-0.0230.0555No
218SLC25A15SLC25A15
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 158751-0.0230.0563No
219SLC25A19SLC25A19
Entrez,  Source
solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 198763-0.0230.0573No
220KCNN2KCNN2
Entrez,  Source
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 28839-0.0240.0534No
221SLC31A1SLC31A1
Entrez,  Source
solute carrier family 31 (copper transporters), member 18908-0.0250.0502No
222ATP2B1ATP2B1
Entrez,  Source
ATPase, Ca++ transporting, plasma membrane 18980-0.0260.0467No
223ATP6V0E1ATP6V0E1
Entrez,  Source
ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e18981-0.0260.0487No
224SLC17A1SLC17A1
Entrez,  Source
solute carrier family 17 (sodium phosphate), member 19109-0.0270.0411No
225SURF1SURF1
Entrez,  Source
surfeit 19180-0.0280.0379No
226P2RX4P2RX4
Entrez,  Source
purinergic receptor P2X, ligand-gated ion channel, 49274-0.0290.0330No
227SLC1A5SLC1A5
Entrez,  Source
solute carrier family 1 (neutral amino acid transporter), member 59379-0.0300.0274No
228SLC25A10SLC25A10
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 109394-0.0300.0287No
229SLC7A2SLC7A2
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 29632-0.0330.0131No
230SLC25A3SLC25A3
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 39966-0.037-0.0095No
231TRPV6TRPV6
Entrez,  Source
transient receptor potential cation channel, subfamily V, member 610024-0.037-0.0110No
232SLC40A1SLC40A1
Entrez,  Source
solute carrier family 40 (iron-regulated transporter), member 110093-0.038-0.0132No
233ASNA1ASNA1
Entrez,  Source
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)10147-0.039-0.0143No
234TRPM2TRPM2
Entrez,  Source
transient receptor potential cation channel, subfamily M, member 210275-0.040-0.0208No
235SLC2A8SLC2A8
Entrez,  Source
solute carrier family 2, (facilitated glucose transporter) member 810279-0.040-0.0179No
236SLC20A2SLC20A2
Entrez,  Source
solute carrier family 20 (phosphate transporter), member 210283-0.040-0.0150No
237ATP1A1ATP1A1
Entrez,  Source
ATPase, Na+/K+ transporting, alpha 1 polypeptide10291-0.041-0.0124No
238SLC1A4SLC1A4
Entrez,  Source
solute carrier family 1 (glutamate/neutral amino acid transporter), member 410292-0.041-0.0093No
239HTR3BHTR3B
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 3B10347-0.041-0.0102No
240SLC12A4SLC12A4
Entrez,  Source
solute carrier family 12 (potassium/chloride transporters), member 410408-0.042-0.0116No
241ABCC3ABCC3
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 310521-0.044-0.0167No
242LASP1LASP1
Entrez,  Source
LIM and SH3 protein 110631-0.045-0.0216No
243CLCN3CLCN3
Entrez,  Source
chloride channel 310689-0.046-0.0224No
244ITPR1ITPR1
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 110751-0.047-0.0234No
245SLC17A5SLC17A5
Entrez,  Source
solute carrier family 17 (anion/sugar transporter), member 511064-0.052-0.0432No
246SLC35A3SLC35A3
Entrez,  Source
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A311099-0.053-0.0417No
247SLC10A2SLC10A2
Entrez,  Source
solute carrier family 10 (sodium/bile acid cotransporter family), member 211112-0.053-0.0385No
248SLC22A8SLC22A8
Entrez,  Source
solute carrier family 22 (organic anion transporter), member 811336-0.058-0.0511No
249TRPC1TRPC1
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 111504-0.060-0.0592No
250SLC17A3SLC17A3
Entrez,  Source
solute carrier family 17 (sodium phosphate), member 311551-0.061-0.0580No
251CUL5CUL5
Entrez,  Source
cullin 511698-0.065-0.0641No
252ATP1A4ATP1A4
Entrez,  Source
ATPase, Na+/K+ transporting, alpha 4 polypeptide11791-0.067-0.0660No
253SLC5A6SLC5A6
Entrez,  Source
solute carrier family 5 (sodium-dependent vitamin transporter), member 611795-0.067-0.0610No
254FXYD2FXYD2
Entrez,  Source
FXYD domain containing ion transport regulator 211964-0.072-0.0683No
255SLC6A6SLC6A6
Entrez,  Source
solute carrier family 6 (neurotransmitter transporter, taurine), member 612056-0.074-0.0695No
256SLC7A9SLC7A9
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 912083-0.075-0.0656No
257CYB5ACYB5A
Entrez,  Source
cytochrome b5 type A (microsomal)12147-0.078-0.0644No
258COX15COX15
Entrez,  Source
COX15 homolog, cytochrome c oxidase assembly protein (yeast)12188-0.079-0.0614No
259SLC2A2SLC2A2
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 212210-0.080-0.0568No
260SLC8A1SLC8A1
Entrez,  Source
solute carrier family 8 (sodium/calcium exchanger), member 112331-0.084-0.0595No
261SLC5A3SLC5A3
Entrez,  Source
solute carrier family 5 (inositol transporters), member 312431-0.088-0.0602No
262SLC12A7SLC12A7
Entrez,  Source
solute carrier family 12 (potassium/chloride transporters), member 712586-0.096-0.0646No
263ATP2C1ATP2C1
Entrez,  Source
ATPase, Ca++ transporting, type 2C, member 112741-0.106-0.0681No
264P2RX5P2RX5
Entrez,  Source
purinergic receptor P2X, ligand-gated ion channel, 512877-0.118-0.0693No
265SLC34A2SLC34A2
Entrez,  Source
solute carrier family 34 (sodium phosphate), member 212890-0.120-0.0609No
266SLC28A2SLC28A2
Entrez,  Source
solute carrier family 28 (sodium-coupled nucleoside transporter), member 212974-0.129-0.0573No
267ABCC2ABCC2
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 212994-0.131-0.0486No
268SLC35B2SLC35B2
Entrez,  Source
solute carrier family 35, member B213012-0.133-0.0395No
269ATP1B1ATP1B1
Entrez,  Source
ATPase, Na+/K+ transporting, beta 1 polypeptide13030-0.136-0.0303No
270SLC15A1SLC15A1
Entrez,  Source
solute carrier family 15 (oligopeptide transporter), member 113115-0.152-0.0249No
271SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 413152-0.163-0.0150No
272SLC22A4SLC22A4
Entrez,  Source
solute carrier family 22 (organic cation transporter), member 413189-0.181-0.0038No
273SLC31A2SLC31A2
Entrez,  Source
solute carrier family 31 (copper transporters), member 213212-0.1990.0099No
Table: GSEA details [plain text format]



Fig 2: SUBSTRATE_SPECIFIC_TRANSMEMBRANE_TRANSPORTER_ACTIVITY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: SUBSTRATE_SPECIFIC_TRANSMEMBRANE_TRANSPORTER_ACTIVITY: Random ES distribution   
Gene set null distribution of ES for SUBSTRATE_SPECIFIC_TRANSMEMBRANE_TRANSPORTER_ACTIVITY