Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | TAKEDA_NUP8_HOXA9_8D_UP |
| Enrichment Score (ES) | 0.38103944 |
| Normalized Enrichment Score (NES) | 1.452175 |
| Nominal p-value | 0.0390625 |
| FDR q-value | 0.29468256 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IFIT3 | IFIT3 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 3 | 8 | 0.357 | 0.0709 | Yes |
| 2 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 25 | 0.248 | 0.1193 | Yes |
| 3 | MX2 | MX2 Entrez, Source | myxovirus (influenza virus) resistance 2 (mouse) | 64 | 0.196 | 0.1557 | Yes |
| 4 | USP18 | USP18 Entrez, Source | ubiquitin specific peptidase 18 | 94 | 0.180 | 0.1896 | Yes |
| 5 | IFI44 | IFI44 Entrez, Source | interferon-induced protein 44 | 157 | 0.157 | 0.2163 | Yes |
| 6 | IFIT1 | IFIT1 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 1 | 366 | 0.128 | 0.2263 | Yes |
| 7 | ENPP2 | ENPP2 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) | 429 | 0.123 | 0.2463 | Yes |
| 8 | TNFAIP6 | TNFAIP6 Entrez, Source | tumor necrosis factor, alpha-induced protein 6 | 543 | 0.114 | 0.2607 | Yes |
| 9 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 655 | 0.107 | 0.2737 | Yes |
| 10 | IGJ | IGJ Entrez, Source | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 764 | 0.101 | 0.2858 | Yes |
| 11 | NEGR1 | NEGR1 Entrez, Source | neuronal growth regulator 1 | 775 | 0.100 | 0.3052 | Yes |
| 12 | IGFBP4 | IGFBP4 Entrez, Source | insulin-like growth factor binding protein 4 | 859 | 0.097 | 0.3184 | Yes |
| 13 | SPOCK1 | SPOCK1 Entrez, Source | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 915 | 0.095 | 0.3332 | Yes |
| 14 | OAS1 | OAS1 Entrez, Source | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 980 | 0.092 | 0.3468 | Yes |
| 15 | NR4A2 | NR4A2 Entrez, Source | nuclear receptor subfamily 4, group A, member 2 | 1011 | 0.091 | 0.3628 | Yes |
| 16 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 1427 | 0.077 | 0.3469 | Yes |
| 17 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 1479 | 0.075 | 0.3582 | Yes |
| 18 | SDPR | SDPR Entrez, Source | serum deprivation response (phosphatidylserine binding protein) | 1545 | 0.074 | 0.3680 | Yes |
| 19 | GZMB | GZMB Entrez, Source | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 1567 | 0.073 | 0.3810 | Yes |
| 20 | TPSAB1 | TPSAB1 Entrez, Source | tryptase alpha/beta 1 | 2261 | 0.056 | 0.3401 | No |
| 21 | ASB2 | ASB2 Entrez, Source | ankyrin repeat and SOCS box-containing 2 | 2403 | 0.054 | 0.3402 | No |
| 22 | APOC1 | APOC1 Entrez, Source | apolipoprotein C-I | 2829 | 0.046 | 0.3174 | No |
| 23 | NMU | NMU Entrez, Source | neuromedin U | 2876 | 0.045 | 0.3229 | No |
| 24 | HERC6 | HERC6 Entrez, Source | hect domain and RLD 6 | 2992 | 0.043 | 0.3229 | No |
| 25 | LTBP3 | LTBP3 Entrez, Source | latent transforming growth factor beta binding protein 3 | 3002 | 0.043 | 0.3308 | No |
| 26 | RHAG | RHAG Entrez, Source | Rh-associated glycoprotein | 3123 | 0.041 | 0.3300 | No |
| 27 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 3481 | 0.035 | 0.3102 | No |
| 28 | IFIT2 | IFIT2 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 2 | 3738 | 0.032 | 0.2974 | No |
| 29 | HBB | HBB Entrez, Source | hemoglobin, beta | 4244 | 0.025 | 0.2644 | No |
| 30 | DEFB1 | DEFB1 Entrez, Source | defensin, beta 1 | 4246 | 0.025 | 0.2694 | No |
| 31 | SLC6A13 | SLC6A13 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, GABA), member 13 | 4362 | 0.024 | 0.2655 | No |
| 32 | IRF7 | IRF7 Entrez, Source | interferon regulatory factor 7 | 4680 | 0.020 | 0.2456 | No |
| 33 | DLC1 | DLC1 Entrez, Source | deleted in liver cancer 1 | 4824 | 0.018 | 0.2385 | No |
| 34 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 4902 | 0.017 | 0.2361 | No |
| 35 | NOG | NOG Entrez, Source | noggin | 4995 | 0.016 | 0.2324 | No |
| 36 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 5344 | 0.012 | 0.2086 | No |
| 37 | OLFM3 | OLFM3 Entrez, Source | olfactomedin 3 | 5571 | 0.009 | 0.1934 | No |
| 38 | LXN | LXN Entrez, Source | latexin | 6581 | -0.002 | 0.1178 | No |
| 39 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 6620 | -0.002 | 0.1154 | No |
| 40 | FGF18 | FGF18 Entrez, Source | fibroblast growth factor 18 | 6630 | -0.002 | 0.1152 | No |
| 41 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 6762 | -0.003 | 0.1060 | No |
| 42 | ANGPT1 | ANGPT1 Entrez, Source | angiopoietin 1 | 7146 | -0.007 | 0.0786 | No |
| 43 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 7778 | -0.013 | 0.0337 | No |
| 44 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 7868 | -0.014 | 0.0299 | No |
| 45 | ATP7B | ATP7B Entrez, Source | ATPase, Cu++ transporting, beta polypeptide | 8306 | -0.019 | 0.0007 | No |
| 46 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 8802 | -0.024 | -0.0317 | No |
| 47 | CALB1 | CALB1 Entrez, Source | calbindin 1, 28kDa | 9321 | -0.029 | -0.0649 | No |
| 48 | SLC12A8 | SLC12A8 Entrez, Source | solute carrier family 12 (potassium/chloride transporters), member 8 | 9350 | -0.030 | -0.0611 | No |
| 49 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 9892 | -0.036 | -0.0946 | No |
| 50 | PPP1R14A | PPP1R14A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 14A | 10021 | -0.037 | -0.0968 | No |
| 51 | SLC40A1 | SLC40A1 Entrez, Source | solute carrier family 40 (iron-regulated transporter), member 1 | 10093 | -0.038 | -0.0944 | No |
| 52 | TSC22D1 | TSC22D1 Entrez, Source | TSC22 domain family, member 1 | 11547 | -0.061 | -0.1916 | No |
| 53 | GDF15 | GDF15 Entrez, Source | growth differentiation factor 15 | 11771 | -0.066 | -0.1951 | No |
| 54 | IL22RA2 | IL22RA2 Entrez, Source | interleukin 22 receptor, alpha 2 | 11846 | -0.069 | -0.1869 | No |
| 55 | REXO2 | REXO2 Entrez, Source | REX2, RNA exonuclease 2 homolog (S. cerevisiae) | 12359 | -0.086 | -0.2083 | No |
| 56 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 12422 | -0.088 | -0.1954 | No |
| 57 | CNKSR3 | CNKSR3 Entrez, Source | CNKSR family member 3 | 12466 | -0.090 | -0.1807 | No |
| 58 | METTL7B | METTL7B Entrez, Source | methyltransferase like 7B | 12605 | -0.097 | -0.1717 | No |
| 59 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 12839 | -0.114 | -0.1664 | No |
| 60 | LGALS3BP | LGALS3BP Entrez, Source | lectin, galactoside-binding, soluble, 3 binding protein | 12844 | -0.115 | -0.1437 | No |
| 61 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 13185 | -0.179 | -0.1336 | No |
| 62 | FHL2 | FHL2 Entrez, Source | four and a half LIM domains 2 | 13253 | -0.222 | -0.0942 | No |
| 63 | PRSS23 | PRSS23 Entrez, Source | protease, serine, 23 | 13336 | -0.503 | 0.0005 | No |
