Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | TNFR1PATHWAY |
| Enrichment Score (ES) | -0.55501765 |
| Normalized Enrichment Score (NES) | -1.6323458 |
| Nominal p-value | 0.024291499 |
| FDR q-value | 0.20897447 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 2879 | 0.045 | -0.1641 | No |
| 2 | MADD | MADD Entrez, Source | MAP-kinase activating death domain | 3637 | 0.033 | -0.1824 | No |
| 3 | JUN | JUN Entrez, Source | jun oncogene | 4841 | 0.018 | -0.2518 | No |
| 4 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 5475 | 0.010 | -0.2873 | No |
| 5 | LMNA | LMNA Entrez, Source | lamin A/C | 6554 | -0.001 | -0.3665 | No |
| 6 | DFFB | DFFB Entrez, Source | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 7293 | -0.009 | -0.4120 | No |
| 7 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 7301 | -0.009 | -0.4025 | No |
| 8 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 7416 | -0.010 | -0.3999 | No |
| 9 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 8457 | -0.020 | -0.4545 | No |
| 10 | TRADD | TRADD Entrez, Source | TNFRSF1A-associated via death domain | 9040 | -0.026 | -0.4675 | No |
| 11 | BAG4 | BAG4 Entrez, Source | BCL2-associated athanogene 4 | 10207 | -0.040 | -0.5092 | Yes |
| 12 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 10273 | -0.040 | -0.4674 | Yes |
| 13 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 10368 | -0.041 | -0.4264 | Yes |
| 14 | DFFA | DFFA Entrez, Source | DNA fragmentation factor, 45kDa, alpha polypeptide | 11119 | -0.053 | -0.4212 | Yes |
| 15 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 11443 | -0.059 | -0.3766 | Yes |
| 16 | FADD | FADD Entrez, Source | Fas (TNFRSF6)-associated via death domain | 12156 | -0.078 | -0.3398 | Yes |
| 17 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12178 | -0.079 | -0.2503 | Yes |
| 18 | PAK2 | PAK2 Entrez, Source | p21 (CDKN1A)-activated kinase 2 | 12379 | -0.086 | -0.1655 | Yes |
| 19 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 12607 | -0.097 | -0.0699 | Yes |
| 20 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 12764 | -0.108 | 0.0434 | Yes |
