Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_24h_versus_single_gel_24h.class.cls
#double_gel_24h_versus_single_gel_24h_repos
Phenotypeclass.cls#double_gel_24h_versus_single_gel_24h_repos
Upregulated in classdouble_gel_24h
GeneSetTRANSMEMBRANE_RECEPTOR_ACTIVITY
Enrichment Score (ES)0.36212322
Normalized Enrichment Score (NES)1.7180899
Nominal p-value0.0
FDR q-value0.1189391
FWER p-Value0.999
Table: GSEA Results Summary



Fig 1: Enrichment plot: TRANSMEMBRANE_RECEPTOR_ACTIVITY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1TAS2R13TAS2R13
Entrez,  Source
taste receptor, type 2, member 13170.2710.0158Yes
2GPR64GPR64
Entrez,  Source
G protein-coupled receptor 64390.2270.0285Yes
3IGF1RIGF1R
Entrez,  Source
insulin-like growth factor 1 receptor760.1890.0376Yes
4CHRNA7CHRNA7
Entrez,  Source
cholinergic receptor, nicotinic, alpha 71070.1750.0464Yes
5GNRHRGNRHR
Entrez,  Source
gonadotropin-releasing hormone receptor1560.1570.0526Yes
6GLP2RGLP2R
Entrez,  Source
glucagon-like peptide 2 receptor1660.1550.0617Yes
7MAS1MAS1
Entrez,  Source
MAS1 oncogene2010.1490.0685Yes
8IL8RAIL8RA
Entrez,  Source
interleukin 8 receptor, alpha2280.1450.0756Yes
9TAS2R10TAS2R10
Entrez,  Source
taste receptor, type 2, member 102800.1380.0804Yes
10OPRM1OPRM1
Entrez,  Source
opioid receptor, mu 12970.1360.0877Yes
11ADRA1AADRA1A
Entrez,  Source
adrenergic, alpha-1A-, receptor3120.1340.0951Yes
12LPHN3LPHN3
Entrez,  Source
latrophilin 33480.1300.1006Yes
13ABCC8ABCC8
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 84720.1200.0987Yes
14CRHR1CRHR1
Entrez,  Source
corticotropin releasing hormone receptor 14730.1200.1063Yes
15CCKBRCCKBR
Entrez,  Source
cholecystokinin B receptor6320.1080.1010Yes
16TRHRTRHR
Entrez,  Source
thyrotropin-releasing hormone receptor6390.1080.1073Yes
17IL6RIL6R
Entrez,  Source
interleukin 6 receptor6950.1040.1097Yes
18MCHR1MCHR1
Entrez,  Source
melanin-concentrating hormone receptor 17020.1040.1158Yes
19CRHR2CRHR2
Entrez,  Source
corticotropin releasing hormone receptor 27170.1030.1212Yes
20VIPR2VIPR2
Entrez,  Source
vasoactive intestinal peptide receptor 27930.1000.1218Yes
21GRM6GRM6
Entrez,  Source
glutamate receptor, metabotropic 68300.0980.1252Yes
22SPNSPN
Entrez,  Source
sialophorin (leukosialin, CD43)8840.0960.1272Yes
23CCKARCCKAR
Entrez,  Source
cholecystokinin A receptor8990.0950.1322Yes
24PTPRHPTPRH
Entrez,  Source
protein tyrosine phosphatase, receptor type, H9160.0950.1369Yes
25GABRR2GABRR2
Entrez,  Source
gamma-aminobutyric acid (GABA) receptor, rho 29410.0940.1410Yes
26GRIA2GRIA2
Entrez,  Source
glutamate receptor, ionotropic, AMPA 29570.0930.1457Yes
27LPHN1LPHN1
Entrez,  Source
latrophilin 19900.0920.1491Yes
28CHRNA3CHRNA3
Entrez,  Source
cholinergic receptor, nicotinic, alpha 39920.0920.1548Yes
29TAS1R3TAS1R3
Entrez,  Source
taste receptor, type 1, member 310150.0910.1588Yes
30DRD3DRD3
Entrez,  Source
dopamine receptor D310480.0900.1620Yes
31CNR1CNR1
Entrez,  Source
cannabinoid receptor 1 (brain)10850.0880.1648Yes
32IL9RIL9R
Entrez,  Source
interleukin 9 receptor10940.0870.1697Yes
33PTHR1PTHR1
Entrez,  Source
parathyroid hormone receptor 110950.0870.1752Yes
34CD3GCD3G
Entrez,  Source
CD3g molecule, gamma (CD3-TCR complex)11290.0860.1781Yes
35F2RL3F2RL3
Entrez,  Source
coagulation factor II (thrombin) receptor-like 311340.0860.1832Yes
36OPRK1OPRK1
Entrez,  Source
opioid receptor, kappa 111420.0860.1881Yes
37IL8RBIL8RB
Entrez,  Source
interleukin 8 receptor, beta11700.0850.1914Yes
38TNFRSF14TNFRSF14
Entrez,  Source
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)11750.0850.1964Yes
39GRIK5GRIK5
Entrez,  Source
glutamate receptor, ionotropic, kainate 511850.0840.2010Yes
40P2RX1P2RX1
Entrez,  Source
purinergic receptor P2X, ligand-gated ion channel, 112000.0840.2052Yes
41KLRC2KLRC2
Entrez,  Source
killer cell lectin-like receptor subfamily C, member 212510.0820.2066Yes
42CD4CD4
Entrez,  Source
CD4 molecule12660.0810.2106Yes
43OPRD1OPRD1
Entrez,  Source
opioid receptor, delta 112670.0810.2158Yes
44CSF1RCSF1R
Entrez,  Source
colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog12830.0810.2197Yes
45GABREGABRE
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, epsilon12850.0810.2247Yes
46FLT4FLT4
Entrez,  Source
fms-related tyrosine kinase 413140.0800.2276Yes
47ELTD1ELTD1
Entrez,  Source
EGF, latrophilin and seven transmembrane domain containing 113390.0790.2308Yes
48CLDN4CLDN4
Entrez,  Source
claudin 413700.0780.2334Yes
49GPR56GPR56
Entrez,  Source
G protein-coupled receptor 5613810.0780.2376Yes
50ADRA2AADRA2A
Entrez,  Source
adrenergic, alpha-2A-, receptor13990.0780.2412Yes
51ASGR2ASGR2
Entrez,  Source
asialoglycoprotein receptor 214630.0760.2411Yes
52GALR1GALR1
Entrez,  Source
galanin receptor 114950.0750.2435Yes
53CHRM5CHRM5
Entrez,  Source
cholinergic receptor, muscarinic 515580.0730.2433Yes
54FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)15590.0730.2479Yes
55GABRA1GABRA1
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, alpha 116410.0710.2462Yes
56PTGFRPTGFR
Entrez,  Source
prostaglandin F receptor (FP)16610.0710.2493Yes
57CMKLR1CMKLR1
Entrez,  Source
chemokine-like receptor 116810.0700.2522Yes
58TNFRSF8TNFRSF8
Entrez,  Source
tumor necrosis factor receptor superfamily, member 817480.0690.2515Yes
59HTR7HTR7
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)17570.0680.2552Yes
60PTPROPTPRO
Entrez,  Source
protein tyrosine phosphatase, receptor type, O17580.0680.2595Yes
61CHRM2CHRM2
Entrez,  Source
cholinergic receptor, muscarinic 217710.0680.2629Yes
62HTR4HTR4
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 417760.0680.2669Yes
63GRPRGRPR
Entrez,  Source
gastrin-releasing peptide receptor18480.0660.2656Yes
64CHRM4CHRM4
Entrez,  Source
cholinergic receptor, muscarinic 418510.0660.2696Yes
65IL12RB2IL12RB2
Entrez,  Source
interleukin 12 receptor, beta 218530.0660.2737Yes
66AVPR1BAVPR1B
Entrez,  Source
arginine vasopressin receptor 1B18700.0660.2766Yes
67NPR2NPR2
Entrez,  Source
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)19240.0640.2766Yes
68OPCMLOPCML
Entrez,  Source
opioid binding protein/cell adhesion molecule-like19880.0630.2758Yes
69DRD1DRD1
Entrez,  Source
dopamine receptor D120050.0620.2785Yes
70SSTR2SSTR2
Entrez,  Source
somatostatin receptor 220140.0620.2818Yes
71CHRM1CHRM1
Entrez,  Source
cholinergic receptor, muscarinic 120920.0600.2797Yes
72KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)20980.0600.2831Yes
73CHRNB2CHRNB2
Entrez,  Source
cholinergic receptor, nicotinic, beta 2 (neuronal)21010.0600.2867Yes
74HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)21100.0600.2899Yes
75TACR3TACR3
Entrez,  Source
tachykinin receptor 321220.0600.2928Yes
76IL4RIL4R
Entrez,  Source
interleukin 4 receptor21300.0590.2960Yes
77ADRB1ADRB1
Entrez,  Source
adrenergic, beta-1-, receptor21310.0590.2997Yes
78LIFRLIFR
Entrez,  Source
leukemia inhibitory factor receptor alpha21790.0580.2998Yes
79OXTROXTR
Entrez,  Source
oxytocin receptor21840.0580.3032Yes
80GABRQGABRQ
Entrez,  Source
gamma-aminobutyric acid (GABA) receptor, theta22430.0560.3023Yes
81PTAFRPTAFR
Entrez,  Source
platelet-activating factor receptor22860.0560.3026Yes
82ADRA2CADRA2C
Entrez,  Source
adrenergic, alpha-2C-, receptor23130.0550.3041Yes
83GABBR2GABBR2
Entrez,  Source
gamma-aminobutyric acid (GABA) B receptor, 223210.0550.3070Yes
84CELSR3CELSR3
Entrez,  Source
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)23260.0550.3101Yes
85HTR5AHTR5A
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 5A23340.0550.3131Yes
86DMBT1DMBT1
Entrez,  Source
deleted in malignant brain tumors 123680.0540.3140Yes
87HRH2HRH2
Entrez,  Source
histamine receptor H223870.0540.3160Yes
88EFNA3EFNA3
Entrez,  Source
ephrin-A324200.0530.3169Yes
89C5AR1C5AR1
Entrez,  Source
complement component 5a receptor 124770.0520.3159Yes
90AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase25050.0510.3171Yes
91PTPRUPTPRU
Entrez,  Source
protein tyrosine phosphatase, receptor type, U25070.0510.3202Yes
92HTR1AHTR1A
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 1A25150.0510.3229Yes
93SCTRSCTR
Entrez,  Source
secretin receptor25160.0510.3262Yes
94AGTR2AGTR2
Entrez,  Source
angiotensin II receptor, type 225190.0510.3292Yes
95GRIK3GRIK3
Entrez,  Source
glutamate receptor, ionotropic, kainate 325250.0510.3321Yes
96ADRA1DADRA1D
Entrez,  Source
adrenergic, alpha-1D-, receptor25540.0510.3331Yes
97TAS2R1TAS2R1
Entrez,  Source
taste receptor, type 2, member 125870.0500.3338Yes
98HRH1HRH1
Entrez,  Source
histamine receptor H126010.0500.3360Yes
99IL5RAIL5RA
Entrez,  Source
interleukin 5 receptor, alpha26040.0500.3389Yes
100PTPRN2PTPRN2
Entrez,  Source
protein tyrosine phosphatase, receptor type, N polypeptide 226050.0500.3421Yes
101TNFRSF4TNFRSF4
Entrez,  Source
tumor necrosis factor receptor superfamily, member 426390.0490.3426Yes
102GRM8GRM8
Entrez,  Source
glutamate receptor, metabotropic 826650.0490.3438Yes
103HTR2AHTR2A
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 2A27000.0480.3442Yes
104EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)27160.0480.3461Yes
105PDGFRBPDGFRB
Entrez,  Source
platelet-derived growth factor receptor, beta polypeptide27270.0480.3483Yes
106KLRC1KLRC1
Entrez,  Source
killer cell lectin-like receptor subfamily C, member 127330.0470.3509Yes
107STAB2STAB2
Entrez,  Source
stabilin 227360.0470.3537Yes
108CRY1CRY1
Entrez,  Source
cryptochrome 1 (photolyase-like)27400.0470.3565Yes
109ACVRL1ACVRL1
Entrez,  Source
activin A receptor type II-like 128000.0460.3549Yes
110PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide28440.0450.3545Yes
111CALCRLCALCRL
Entrez,  Source
calcitonin receptor-like28680.0450.3555Yes
112HTR6HTR6
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 629400.0440.3529Yes
113IL13RA2IL13RA2
Entrez,  Source
interleukin 13 receptor, alpha 229620.0440.3540Yes
114CYSLTR1CYSLTR1
Entrez,  Source
cysteinyl leukotriene receptor 129720.0430.3561Yes
115GRM4GRM4
Entrez,  Source
glutamate receptor, metabotropic 430140.0430.3556Yes
116ASGR1ASGR1
Entrez,  Source
asialoglycoprotein receptor 130230.0430.3577Yes
117IL2RBIL2RB
Entrez,  Source
interleukin 2 receptor, beta30500.0420.3584Yes
118GABRB2GABRB2
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, beta 230710.0420.3595Yes
119GALR3GALR3
Entrez,  Source
galanin receptor 330770.0420.3617Yes
120LDLRLDLR
Entrez,  Source
low density lipoprotein receptor (familial hypercholesterolemia)31100.0410.3619Yes
121TACR2TACR2
Entrez,  Source
tachykinin receptor 231420.0410.3621Yes
122SSTR4SSTR4
Entrez,  Source
somatostatin receptor 432230.0400.3585No
123NRP2NRP2
Entrez,  Source
neuropilin 232250.0400.3609No
124NTRK1NTRK1
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 133080.0380.3571No
125GFRA2GFRA2
Entrez,  Source
GDNF family receptor alpha 233940.0370.3529No
126PTGER2PTGER2
Entrez,  Source
prostaglandin E receptor 2 (subtype EP2), 53kDa34780.0360.3487No
127COLEC12COLEC12
Entrez,  Source
collectin sub-family member 1236010.0340.3415No
128GABRDGABRD
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, delta36070.0340.3433No
129GABRB3GABRB3
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, beta 336700.0330.3406No
130HTR2BHTR2B
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 2B36840.0330.3417No
131F2RL2F2RL2
Entrez,  Source
coagulation factor II (thrombin) receptor-like 237080.0320.3420No
132ADRB3ADRB3
Entrez,  Source
adrenergic, beta-3-, receptor37430.0320.3414No
133PAX8PAX8
Entrez,  Source
paired box gene 837920.0310.3397No
134GABRR1GABRR1
Entrez,  Source
gamma-aminobutyric acid (GABA) receptor, rho 138630.0300.3362No
135PDGFRLPDGFRL
Entrez,  Source
platelet-derived growth factor receptor-like38660.0300.3379No
136PTPRNPTPRN
Entrez,  Source
protein tyrosine phosphatase, receptor type, N39090.0300.3366No
137PTPRCPTPRC
Entrez,  Source
protein tyrosine phosphatase, receptor type, C39400.0290.3361No
138IL10RAIL10RA
Entrez,  Source
interleukin 10 receptor, alpha39420.0290.3379No
139VIPR1VIPR1
Entrez,  Source
vasoactive intestinal peptide receptor 139430.0290.3397No
140EPHA5EPHA5
Entrez,  Source
EPH receptor A539470.0290.3414No
141GFRA1GFRA1
Entrez,  Source
GDNF family receptor alpha 139970.0280.3394No
142CNTFRCNTFR
Entrez,  Source
ciliary neurotrophic factor receptor40040.0280.3407No
143CHRNA6CHRNA6
Entrez,  Source
cholinergic receptor, nicotinic, alpha 640140.0280.3418No
144GABRB1GABRB1
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, beta 140330.0280.3422No
145IL2RAIL2RA
Entrez,  Source
interleukin 2 receptor, alpha40570.0280.3422No
146DRD2DRD2
Entrez,  Source
dopamine receptor D240820.0270.3420No
147TBXA2RTBXA2R
Entrez,  Source
thromboxane A2 receptor41130.0270.3414No
148EBPEBP
Entrez,  Source
emopamil binding protein (sterol isomerase)41200.0270.3427No
149GRIK1GRIK1
Entrez,  Source
glutamate receptor, ionotropic, kainate 141700.0260.3406No
150GRIN2BGRIN2B
Entrez,  Source
glutamate receptor, ionotropic, N-methyl D-aspartate 2B42060.0260.3395No
151DRD4DRD4
Entrez,  Source
dopamine receptor D442200.0260.3401No
152EPOREPOR
Entrez,  Source
erythropoietin receptor44110.0230.3270No
153AVPR2AVPR2
Entrez,  Source
arginine vasopressin receptor 2 (nephrogenic diabetes insipidus)44890.0220.3225No
154GRM2GRM2
Entrez,  Source
glutamate receptor, metabotropic 244990.0220.3232No
155GRM5GRM5
Entrez,  Source
glutamate receptor, metabotropic 545090.0220.3239No
156CHRNA2CHRNA2
Entrez,  Source
cholinergic receptor, nicotinic, alpha 2 (neuronal)45150.0220.3249No
157C3AR1C3AR1
Entrez,  Source
complement component 3a receptor 145270.0210.3254No
158GRM1GRM1
Entrez,  Source
glutamate receptor, metabotropic 145580.0210.3244No
159TACR1TACR1
Entrez,  Source
tachykinin receptor 146580.0200.3181No
160ADRA2BADRA2B
Entrez,  Source
adrenergic, alpha-2B-, receptor47510.0190.3123No
161HTR1BHTR1B
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 1B47670.0190.3123No
162PTPRDPTPRD
Entrez,  Source
protein tyrosine phosphatase, receptor type, D48080.0180.3104No
163DRD5DRD5
Entrez,  Source
dopamine receptor D548950.0170.3049No
164FGFR1FGFR1
Entrez,  Source
fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)49220.0170.3040No
165TIE1TIE1
Entrez,  Source
tyrosine kinase with immunoglobulin-like and EGF-like domains 149800.0160.3007No
166GRIA1GRIA1
Entrez,  Source
glutamate receptor, ionotropic, AMPA 149940.0160.3007No
167NRP1NRP1
Entrez,  Source
neuropilin 150470.0150.2977No
168OPN4OPN4
Entrez,  Source
opsin 4 (melanopsin)51060.0150.2942No
169NMUR2NMUR2
Entrez,  Source
neuromedin U receptor 253670.0120.2750No
170ERBB3ERBB3
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)54050.0110.2729No
171TNFRSF1ATNFRSF1A
Entrez,  Source
tumor necrosis factor receptor superfamily, member 1A54750.0100.2683No
172DDR2DDR2
Entrez,  Source
discoidin domain receptor family, member 255220.0100.2654No
173PTGER3PTGER3
Entrez,  Source
prostaglandin E receptor 3 (subtype EP3)56340.0090.2574No
174BDKRB1BDKRB1
Entrez,  Source
bradykinin receptor B157010.0080.2529No
175CLEC4ACLEC4A
Entrez,  Source
C-type lectin domain family 4, member A57550.0070.2493No
176PTPRMPTPRM
Entrez,  Source
protein tyrosine phosphatase, receptor type, M57680.0070.2488No
177GPR116GPR116
Entrez,  Source
G protein-coupled receptor 11658180.0070.2455No
178HRH3HRH3
Entrez,  Source
histamine receptor H358510.0060.2434No
179IL1R1IL1R1
Entrez,  Source
interleukin 1 receptor, type I58600.0060.2432No
180CHRNA4CHRNA4
Entrez,  Source
cholinergic receptor, nicotinic, alpha 459060.0050.2401No
181LRPAP1LRPAP1
Entrez,  Source
low density lipoprotein receptor-related protein associated protein 159320.0050.2385No
182ACVR2AACVR2A
Entrez,  Source
activin A receptor, type IIA59570.0050.2369No
183TSHRTSHR
Entrez,  Source
thyroid stimulating hormone receptor59690.0050.2364No
184LANCL1LANCL1
Entrez,  Source
LanC lantibiotic synthetase component C-like 1 (bacterial)60330.0040.2319No
185GRK1GRK1
Entrez,  Source
G protein-coupled receptor kinase 161420.0030.2238No
186P2RXL1P2RXL1
Entrez,  Source
purinergic receptor P2X-like 1, orphan receptor62780.0020.2136No
187NMUR1NMUR1
Entrez,  Source
neuromedin U receptor 163040.0010.2117No
188GHRHRGHRHR
Entrez,  Source
growth hormone releasing hormone receptor63300.0010.2099No
189INTS6INTS6
Entrez,  Source
integrator complex subunit 663930.0000.2051No
190MC5RMC5R
Entrez,  Source
melanocortin 5 receptor6584-0.0020.1907No
191RPSARPSA
Entrez,  Source
ribosomal protein SA6735-0.0030.1794No
192EPHB6EPHB6
Entrez,  Source
EPH receptor B66786-0.0040.1758No
193CHRNECHRNE
Entrez,  Source
cholinergic receptor, nicotinic, epsilon6825-0.0040.1732No
194GRIK4GRIK4
Entrez,  Source
glutamate receptor, ionotropic, kainate 46854-0.0040.1713No
195CLDN3CLDN3
Entrez,  Source
claudin 36913-0.0050.1671No
196BDKRB2BDKRB2
Entrez,  Source
bradykinin receptor B27014-0.0060.1598No
197GRIN2AGRIN2A
Entrez,  Source
glutamate receptor, ionotropic, N-methyl D-aspartate 2A7043-0.0060.1581No
198PTGER1PTGER1
Entrez,  Source
prostaglandin E receptor 1 (subtype EP1), 42kDa7055-0.0060.1576No
199TAS2R16TAS2R16
Entrez,  Source
taste receptor, type 2, member 167161-0.0070.1500No
200CHRNB4CHRNB4
Entrez,  Source
cholinergic receptor, nicotinic, beta 47214-0.0080.1466No
201LPHN2LPHN2
Entrez,  Source
latrophilin 27314-0.0090.1395No
202ACVR1ACVR1
Entrez,  Source
activin A receptor, type I7360-0.0090.1367No
203CD97CD97
Entrez,  Source
CD97 molecule7419-0.0100.1328No
204PTPRZ1PTPRZ1
Entrez,  Source
protein tyrosine phosphatase, receptor-type, Z polypeptide 17455-0.0100.1308No
205TGFBR1TGFBR1
Entrez,  Source
transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)7514-0.0110.1270No
206ACVR2BACVR2B
Entrez,  Source
activin A receptor, type IIB7574-0.0110.1232No
207CHRNA1CHRNA1
Entrez,  Source
cholinergic receptor, nicotinic, alpha 1 (muscle)7580-0.0110.1235No
208ABCC9ABCC9
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 97637-0.0120.1200No
209PTPREPTPRE
Entrez,  Source
protein tyrosine phosphatase, receptor type, E7668-0.0120.1185No
210TAS2R7TAS2R7
Entrez,  Source
taste receptor, type 2, member 77805-0.0140.1089No
211NMBRNMBR
Entrez,  Source
neuromedin B receptor7890-0.0140.1034No
212GHSRGHSR
Entrez,  Source
growth hormone secretagogue receptor8118-0.0170.0871No
213GRIN2CGRIN2C
Entrez,  Source
glutamate receptor, ionotropic, N-methyl D-aspartate 2C8176-0.0170.0838No
214KISS1RKISS1R
Entrez,  Source
KISS1 receptor8190-0.0180.0839No
215GRIK2GRIK2
Entrez,  Source
glutamate receptor, ionotropic, kainate 28233-0.0180.0818No
216CLEC2DCLEC2D
Entrez,  Source
C-type lectin domain family 2, member D8305-0.0190.0776No
217IGSF6IGSF6
Entrez,  Source
immunoglobulin superfamily, member 68396-0.0200.0719No
218INSRINSR
Entrez,  Source
insulin receptor8403-0.0200.0727No
219ROBO1ROBO1
Entrez,  Source
roundabout, axon guidance receptor, homolog 1 (Drosophila)8442-0.0200.0711No
220HCRTR2HCRTR2
Entrez,  Source
hypocretin (orexin) receptor 28532-0.0210.0656No
221GABRPGABRP
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, pi8657-0.0220.0575No
222ALKALK
Entrez,  Source
anaplastic lymphoma kinase (Ki-1)8660-0.0220.0588No
223HTR1FHTR1F
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 1F8917-0.0250.0407No
224PTGER4PTGER4
Entrez,  Source
prostaglandin E receptor 4 (subtype EP4)8928-0.0250.0416No
225IL3RAIL3RA
Entrez,  Source
interleukin 3 receptor, alpha (low affinity)9102-0.0270.0300No
226MERTKMERTK
Entrez,  Source
c-mer proto-oncogene tyrosine kinase9123-0.0270.0302No
227AGERAGER
Entrez,  Source
advanced glycosylation end product-specific receptor9237-0.0280.0234No
228GALR2GALR2
Entrez,  Source
galanin receptor 29407-0.0300.0123No
229FGFR4FGFR4
Entrez,  Source
fibroblast growth factor receptor 49601-0.033-0.0004No
230M6PRM6PR
Entrez,  Source
mannose-6-phosphate receptor (cation dependent)9614-0.0330.0008No
231ERBB4ERBB4
Entrez,  Source
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)9620-0.0330.0025No
232TAS2R5TAS2R5
Entrez,  Source
taste receptor, type 2, member 59646-0.0330.0027No
233SSTR5SSTR5
Entrez,  Source
somatostatin receptor 59703-0.0340.0005No
234PTPRRPTPRR
Entrez,  Source
protein tyrosine phosphatase, receptor type, R9705-0.0340.0026No
235IL6STIL6ST
Entrez,  Source
interleukin 6 signal transducer (gp130, oncostatin M receptor)9951-0.037-0.0139No
236CHRM3CHRM3
Entrez,  Source
cholinergic receptor, muscarinic 39961-0.037-0.0122No
237UNC5CUNC5C
Entrez,  Source
unc-5 homolog C (C. elegans)10079-0.038-0.0188No
238SSTR1SSTR1
Entrez,  Source
somatostatin receptor 110304-0.041-0.0334No
239HTR3BHTR3B
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 3B10347-0.041-0.0340No
240GHRGHR
Entrez,  Source
growth hormone receptor10389-0.042-0.0345No
241GRM7GRM7
Entrez,  Source
glutamate receptor, metabotropic 710566-0.044-0.0452No
242LILRB3LILRB3
Entrez,  Source
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 310569-0.044-0.0425No
243PTPRJPTPRJ
Entrez,  Source
protein tyrosine phosphatase, receptor type, J10684-0.046-0.0484No
244CNR2CNR2
Entrez,  Source
cannabinoid receptor 2 (macrophage)10772-0.048-0.0520No
245NPYNPY
Entrez,  Source
neuropeptide Y10886-0.049-0.0576No
246ACVR1CACVR1C
Entrez,  Source
activin A receptor, type IC10894-0.050-0.0550No
247IGF2RIGF2R
Entrez,  Source
insulin-like growth factor 2 receptor11234-0.056-0.0774No
248GCGRGCGR
Entrez,  Source
glucagon receptor11253-0.056-0.0753No
249KLRD1KLRD1
Entrez,  Source
killer cell lectin-like receptor subfamily D, member 111404-0.059-0.0830No
250GPR175GPR175
Entrez,  Source
G protein-coupled receptor 17511554-0.061-0.0906No
251MC4RMC4R
Entrez,  Source
melanocortin 4 receptor11608-0.063-0.0907No
252RYKRYK
Entrez,  Source
RYK receptor-like tyrosine kinase11696-0.065-0.0933No
253ICAM1ICAM1
Entrez,  Source
intercellular adhesion molecule 1 (CD54), human rhinovirus receptor11718-0.065-0.0908No
254IL22RA2IL22RA2
Entrez,  Source
interleukin 22 receptor, alpha 211846-0.069-0.0962No
255VLDLRVLDLR
Entrez,  Source
very low density lipoprotein receptor11859-0.069-0.0927No
256GABBR1GABBR1
Entrez,  Source
gamma-aminobutyric acid (GABA) B receptor, 111865-0.069-0.0888No
257PTPRFPTPRF
Entrez,  Source
protein tyrosine phosphatase, receptor type, F11972-0.072-0.0924No
258PTPRKPTPRK
Entrez,  Source
protein tyrosine phosphatase, receptor type, K11989-0.073-0.0890No
259ADRA1BADRA1B
Entrez,  Source
adrenergic, alpha-1B-, receptor12029-0.074-0.0874No
260FZD6FZD6
Entrez,  Source
frizzled homolog 6 (Drosophila)12054-0.074-0.0845No
261DDR1DDR1
Entrez,  Source
discoidin domain receptor family, member 112120-0.077-0.0846No
262IFNGR1IFNGR1
Entrez,  Source
interferon gamma receptor 112154-0.078-0.0823No
263TYRO3TYRO3
Entrez,  Source
TYRO3 protein tyrosine kinase12342-0.085-0.0912No
264MUSKMUSK
Entrez,  Source
muscle, skeletal, receptor tyrosine kinase12393-0.087-0.0896No
265CHRNA5CHRNA5
Entrez,  Source
cholinergic receptor, nicotinic, alpha 512619-0.098-0.1007No
266BCAMBCAM
Entrez,  Source
basal cell adhesion molecule (Lutheran blood group)12684-0.102-0.0991No
267CD69CD69
Entrez,  Source
CD69 molecule12743-0.106-0.0969No
268IL2RGIL2RG
Entrez,  Source
interleukin 2 receptor, gamma (severe combined immunodeficiency)12775-0.109-0.0924No
269F2RF2R
Entrez,  Source
coagulation factor II (thrombin) receptor12839-0.114-0.0900No
270LGALS3BPLGALS3BP
Entrez,  Source
lectin, galactoside-binding, soluble, 3 binding protein12844-0.115-0.0831No
271P2RX5P2RX5
Entrez,  Source
purinergic receptor P2X, ligand-gated ion channel, 512877-0.118-0.0781No
272CHRNB1CHRNB1
Entrez,  Source
cholinergic receptor, nicotinic, beta 1 (muscle)12969-0.128-0.0770No
273FZD3FZD3
Entrez,  Source
frizzled homolog 3 (Drosophila)12973-0.128-0.0691No
274TGFBR2TGFBR2
Entrez,  Source
transforming growth factor, beta receptor II (70/80kDa)13036-0.137-0.0652No
275CXCL16CXCL16
Entrez,  Source
chemokine (C-X-C motif) ligand 1613080-0.146-0.0593No
276GRM3GRM3
Entrez,  Source
glutamate receptor, metabotropic 313128-0.156-0.0531No
277METMET
Entrez,  Source
met proto-oncogene (hepatocyte growth factor receptor)13148-0.161-0.0445No
278FZD4FZD4
Entrez,  Source
frizzled homolog 4 (Drosophila)13170-0.170-0.0353No
279EMR1EMR1
Entrez,  Source
egf-like module containing, mucin-like, hormone receptor-like 113220-0.205-0.0261No
280AVPR1AAVPR1A
Entrez,  Source
arginine vasopressin receptor 1A13282-0.262-0.0143No
281ADRB2ADRB2
Entrez,  Source
adrenergic, beta-2-, receptor, surface13304-0.2980.0029No
Table: GSEA details [plain text format]



Fig 2: TRANSMEMBRANE_RECEPTOR_ACTIVITY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: TRANSMEMBRANE_RECEPTOR_ACTIVITY: Random ES distribution   
Gene set null distribution of ES for TRANSMEMBRANE_RECEPTOR_ACTIVITY