Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | TYROSINE_METABOLISM |
| Enrichment Score (ES) | 0.47416943 |
| Normalized Enrichment Score (NES) | 1.4775149 |
| Nominal p-value | 0.051485147 |
| FDR q-value | 0.28074822 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TPO | TPO Entrez, Source | thyroid peroxidase | 150 | 0.159 | 0.1209 | Yes |
| 2 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 214 | 0.147 | 0.2380 | Yes |
| 3 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 374 | 0.128 | 0.3324 | Yes |
| 4 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 959 | 0.093 | 0.3660 | Yes |
| 5 | PNMT | PNMT Entrez, Source | phenylethanolamine N-methyltransferase | 972 | 0.093 | 0.4420 | Yes |
| 6 | TAT | TAT Entrez, Source | tyrosine aminotransferase | 2165 | 0.058 | 0.4010 | Yes |
| 7 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 2193 | 0.058 | 0.4469 | Yes |
| 8 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 2425 | 0.053 | 0.4737 | Yes |
| 9 | AOX1 | AOX1 Entrez, Source | aldehyde oxidase 1 | 3148 | 0.041 | 0.4535 | Yes |
| 10 | DBH | DBH Entrez, Source | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | 3789 | 0.031 | 0.4315 | Yes |
| 11 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 3861 | 0.030 | 0.4512 | Yes |
| 12 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 3886 | 0.030 | 0.4742 | Yes |
| 13 | TH | TH Entrez, Source | tyrosine hydroxylase | 4532 | 0.021 | 0.4436 | No |
| 14 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 5228 | 0.013 | 0.4025 | No |
| 15 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 5527 | 0.010 | 0.3884 | No |
| 16 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 5731 | 0.008 | 0.3795 | No |
| 17 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 6634 | -0.002 | 0.3137 | No |
| 18 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 6761 | -0.003 | 0.3071 | No |
| 19 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 6965 | -0.005 | 0.2962 | No |
| 20 | COMT | COMT Entrez, Source | catechol-O-methyltransferase | 8288 | -0.019 | 0.2124 | No |
| 21 | ALDH3B1 | ALDH3B1 Entrez, Source | aldehyde dehydrogenase 3 family, member B1 | 9992 | -0.037 | 0.1153 | No |
| 22 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 9998 | -0.037 | 0.1457 | No |
| 23 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 11520 | -0.061 | 0.0820 | No |
| 24 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 11749 | -0.066 | 0.1196 | No |
