Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | UVB_NHEK3_C8 |
| Enrichment Score (ES) | -0.51213866 |
| Normalized Enrichment Score (NES) | -1.8279891 |
| Nominal p-value | 0.0020 |
| FDR q-value | 0.120731965 |
| FWER p-Value | 0.936 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FBN2 | FBN2 Entrez, Source | fibrillin 2 (congenital contractural arachnodactyly) | 368 | 0.128 | 0.0152 | No |
| 2 | FASN | FASN Entrez, Source | fatty acid synthase | 607 | 0.110 | 0.0340 | No |
| 3 | FDFT1 | FDFT1 Entrez, Source | farnesyl-diphosphate farnesyltransferase 1 | 952 | 0.094 | 0.0394 | No |
| 4 | GJB2 | GJB2 Entrez, Source | gap junction protein, beta 2, 26kDa (connexin 26) | 1398 | 0.078 | 0.0319 | No |
| 5 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1411 | 0.077 | 0.0568 | No |
| 6 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 1596 | 0.073 | 0.0672 | No |
| 7 | ST6GALNAC2 | ST6GALNAC2 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 1660 | 0.071 | 0.0862 | No |
| 8 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 2130 | 0.059 | 0.0708 | No |
| 9 | HK1 | HK1 Entrez, Source | hexokinase 1 | 2841 | 0.045 | 0.0326 | No |
| 10 | FHL1 | FHL1 Entrez, Source | four and a half LIM domains 1 | 2980 | 0.043 | 0.0367 | No |
| 11 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 3169 | 0.041 | 0.0361 | No |
| 12 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 4407 | 0.023 | -0.0491 | No |
| 13 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 4803 | 0.018 | -0.0727 | No |
| 14 | PGM1 | PGM1 Entrez, Source | phosphoglucomutase 1 | 5224 | 0.013 | -0.0998 | No |
| 15 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 5828 | 0.006 | -0.1429 | No |
| 16 | TMED10 | TMED10 Entrez, Source | transmembrane emp24-like trafficking protein 10 (yeast) | 6170 | 0.003 | -0.1677 | No |
| 17 | SLC2A1 | SLC2A1 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 1 | 6242 | 0.002 | -0.1724 | No |
| 18 | TOMM20 | TOMM20 Entrez, Source | translocase of outer mitochondrial membrane 20 homolog (yeast) | 6756 | -0.003 | -0.2098 | No |
| 19 | PON2 | PON2 Entrez, Source | paraoxonase 2 | 7149 | -0.007 | -0.2369 | No |
| 20 | PTPRZ1 | PTPRZ1 Entrez, Source | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 7455 | -0.010 | -0.2565 | No |
| 21 | R3HDM1 | R3HDM1 Entrez, Source | R3H domain containing 1 | 7477 | -0.010 | -0.2546 | No |
| 22 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 7670 | -0.012 | -0.2650 | No |
| 23 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 7800 | -0.014 | -0.2702 | No |
| 24 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 7807 | -0.014 | -0.2661 | No |
| 25 | FLNB | FLNB Entrez, Source | filamin B, beta (actin binding protein 278) | 7935 | -0.015 | -0.2706 | No |
| 26 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 7976 | -0.015 | -0.2685 | No |
| 27 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 8252 | -0.018 | -0.2831 | No |
| 28 | PRDX6 | PRDX6 Entrez, Source | peroxiredoxin 6 | 8269 | -0.018 | -0.2781 | No |
| 29 | PFN2 | PFN2 Entrez, Source | profilin 2 | 8811 | -0.024 | -0.3108 | No |
| 30 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 9698 | -0.034 | -0.3660 | No |
| 31 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 9796 | -0.035 | -0.3616 | No |
| 32 | ATP5O | ATP5O Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 10128 | -0.039 | -0.3736 | No |
| 33 | PTPRF | PTPRF Entrez, Source | protein tyrosine phosphatase, receptor type, F | 11972 | -0.072 | -0.4881 | Yes |
| 34 | PTPRK | PTPRK Entrez, Source | protein tyrosine phosphatase, receptor type, K | 11989 | -0.073 | -0.4651 | Yes |
| 35 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 12014 | -0.073 | -0.4424 | Yes |
| 36 | GLG1 | GLG1 Entrez, Source | golgi apparatus protein 1 | 12240 | -0.081 | -0.4323 | Yes |
| 37 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 12333 | -0.084 | -0.4110 | Yes |
| 38 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 12679 | -0.101 | -0.4031 | Yes |
| 39 | SCRN1 | SCRN1 Entrez, Source | secernin 1 | 12790 | -0.110 | -0.3746 | Yes |
| 40 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 13011 | -0.133 | -0.3466 | Yes |
| 41 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 13185 | -0.179 | -0.2999 | Yes |
| 42 | FGFR3 | FGFR3 Entrez, Source | fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) | 13275 | -0.244 | -0.2249 | Yes |
| 43 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13314 | -0.341 | -0.1139 | Yes |
| 44 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 13317 | -0.347 | 0.0019 | Yes |
