Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | UVB_SCC_UP |
| Enrichment Score (ES) | -0.39093366 |
| Normalized Enrichment Score (NES) | -1.4659647 |
| Nominal p-value | 0.02357564 |
| FDR q-value | 0.29925376 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CCBP2 | CCBP2 Entrez, Source | chemokine binding protein 2 | 197 | 0.149 | 0.0371 | No |
| 2 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 502 | 0.118 | 0.0551 | No |
| 3 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 1287 | 0.081 | 0.0242 | No |
| 4 | PDIA6 | PDIA6 Entrez, Source | protein disulfide isomerase family A, member 6 | 1706 | 0.070 | 0.0169 | No |
| 5 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 1933 | 0.064 | 0.0221 | No |
| 6 | TAGLN3 | TAGLN3 Entrez, Source | transgelin 3 | 2792 | 0.046 | -0.0264 | No |
| 7 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 2879 | 0.045 | -0.0173 | No |
| 8 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3035 | 0.043 | -0.0142 | No |
| 9 | SCFD1 | SCFD1 Entrez, Source | sec1 family domain containing 1 | 4138 | 0.026 | -0.0879 | No |
| 10 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 4172 | 0.026 | -0.0814 | No |
| 11 | SSR1 | SSR1 Entrez, Source | signal sequence receptor, alpha (translocon-associated protein alpha) | 4186 | 0.026 | -0.0733 | No |
| 12 | COPB1 | COPB1 Entrez, Source | coatomer protein complex, subunit beta 1 | 4299 | 0.025 | -0.0732 | No |
| 13 | JUND | JUND Entrez, Source | jun D proto-oncogene | 4321 | 0.024 | -0.0663 | No |
| 14 | LAMP2 | LAMP2 Entrez, Source | lysosomal-associated membrane protein 2 | 4416 | 0.023 | -0.0653 | No |
| 15 | ADK | ADK Entrez, Source | adenosine kinase | 4457 | 0.022 | -0.0605 | No |
| 16 | TSC22D3 | TSC22D3 Entrez, Source | TSC22 domain family, member 3 | 5572 | 0.009 | -0.1411 | No |
| 17 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 5631 | 0.009 | -0.1424 | No |
| 18 | SCYE1 | SCYE1 Entrez, Source | small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) | 5924 | 0.005 | -0.1626 | No |
| 19 | ITM2B | ITM2B Entrez, Source | integral membrane protein 2B | 6118 | 0.003 | -0.1759 | No |
| 20 | HRSP12 | HRSP12 Entrez, Source | heat-responsive protein 12 | 6345 | 0.001 | -0.1926 | No |
| 21 | RBMXL1 | RBMXL1 Entrez, Source | RNA binding motif protein, X-linked-like 1 | 6472 | -0.000 | -0.2019 | No |
| 22 | HPRT1 | HPRT1 Entrez, Source | hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) | 6770 | -0.004 | -0.2231 | No |
| 23 | B2M | B2M Entrez, Source | beta-2-microglobulin | 6897 | -0.005 | -0.2310 | No |
| 24 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 6990 | -0.006 | -0.2360 | No |
| 25 | PRKAR1A | PRKAR1A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 7099 | -0.007 | -0.2418 | No |
| 26 | UBE2D3 | UBE2D3 Entrez, Source | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 7172 | -0.007 | -0.2447 | No |
| 27 | SCARB2 | SCARB2 Entrez, Source | scavenger receptor class B, member 2 | 7224 | -0.008 | -0.2458 | No |
| 28 | ATP6AP2 | ATP6AP2 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 2 | 7420 | -0.010 | -0.2571 | No |
| 29 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 7608 | -0.012 | -0.2672 | No |
| 30 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 7610 | -0.012 | -0.2632 | No |
| 31 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 7766 | -0.013 | -0.2703 | No |
| 32 | SKP1A | SKP1A Entrez, Source | S-phase kinase-associated protein 1A (p19A) | 7902 | -0.015 | -0.2754 | No |
| 33 | CCNC | CCNC Entrez, Source | cyclin C | 7915 | -0.015 | -0.2712 | No |
| 34 | TAF2 | TAF2 Entrez, Source | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 8418 | -0.020 | -0.3020 | No |
| 35 | IL13RA1 | IL13RA1 Entrez, Source | interleukin 13 receptor, alpha 1 | 8528 | -0.021 | -0.3030 | No |
| 36 | ATP5A1 | ATP5A1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle | 8671 | -0.023 | -0.3058 | No |
| 37 | HSP90AB1 | HSP90AB1 Entrez, Source | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 9017 | -0.026 | -0.3227 | No |
| 38 | PTK9 | PTK9 Entrez, Source | PTK9 protein tyrosine kinase 9 | 9524 | -0.032 | -0.3498 | No |
| 39 | PRDX3 | PRDX3 Entrez, Source | peroxiredoxin 3 | 9635 | -0.033 | -0.3465 | No |
| 40 | YWHAZ | YWHAZ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 9759 | -0.035 | -0.3438 | No |
| 41 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 10047 | -0.038 | -0.3522 | No |
| 42 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 10357 | -0.041 | -0.3611 | No |
| 43 | UQCRC2 | UQCRC2 Entrez, Source | ubiquinol-cytochrome c reductase core protein II | 10520 | -0.044 | -0.3581 | No |
| 44 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 10835 | -0.049 | -0.3648 | No |
| 45 | RCN2 | RCN2 Entrez, Source | reticulocalbin 2, EF-hand calcium binding domain | 11041 | -0.052 | -0.3623 | No |
| 46 | TACSTD2 | TACSTD2 Entrez, Source | tumor-associated calcium signal transducer 2 | 11116 | -0.053 | -0.3494 | No |
| 47 | RECQL | RECQL Entrez, Source | RecQ protein-like (DNA helicase Q1-like) | 11262 | -0.056 | -0.3408 | No |
| 48 | NAP1L1 | NAP1L1 Entrez, Source | nucleosome assembly protein 1-like 1 | 11929 | -0.071 | -0.3664 | Yes |
| 49 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 11987 | -0.072 | -0.3455 | Yes |
| 50 | ALDH7A1 | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 12088 | -0.076 | -0.3267 | Yes |
| 51 | RALB | RALB Entrez, Source | v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) | 12089 | -0.076 | -0.3005 | Yes |
| 52 | RTN4 | RTN4 Entrez, Source | reticulon 4 | 12773 | -0.109 | -0.3141 | Yes |
| 53 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 12899 | -0.121 | -0.2814 | Yes |
| 54 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 13084 | -0.146 | -0.2443 | Yes |
| 55 | DYNC2LI1 | DYNC2LI1 Entrez, Source | dynein, cytoplasmic 2, light intermediate chain 1 | 13099 | -0.150 | -0.1932 | Yes |
| 56 | PLSCR1 | PLSCR1 Entrez, Source | phospholipid scramblase 1 | 13117 | -0.153 | -0.1415 | Yes |
| 57 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 13255 | -0.224 | -0.0738 | Yes |
| 58 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13262 | -0.231 | 0.0060 | Yes |
