Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_24h_versus_single_gel_24h.class.cls
#double_gel_24h_versus_single_gel_24h_repos
Phenotypeclass.cls#double_gel_24h_versus_single_gel_24h_repos
Upregulated in classsingle_gel_24h
GeneSetUVC_HIGH_ALL_DN
Enrichment Score (ES)-0.3455874
Normalized Enrichment Score (NES)-1.50934
Nominal p-value0.0
FDR q-value0.27325168
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: UVC_HIGH_ALL_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1DDIT4DDIT4
Entrez,  Source
DNA-damage-inducible transcript 4250.2480.0259No
2IDI1IDI1
Entrez,  Source
isopentenyl-diphosphate delta isomerase 1290.2380.0523No
3HERPUD1HERPUD1
Entrez,  Source
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1740.1890.0701No
4CXCL12CXCL12
Entrez,  Source
chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)1050.1750.0875No
5BHLHB2BHLHB2
Entrez,  Source
basic helix-loop-helix domain containing, class B, 21640.1550.1005No
6IGF2BP3IGF2BP3
Entrez,  Source
insulin-like growth factor 2 mRNA binding protein 31990.1490.1146No
7DUSP5DUSP5
Entrez,  Source
dual specificity phosphatase 52060.1480.1307No
8HMGCRHMGCR
Entrez,  Source
3-hydroxy-3-methylglutaryl-Coenzyme A reductase2500.1410.1433No
9FZD2FZD2
Entrez,  Source
frizzled homolog 2 (Drosophila)3600.1290.1494No
10IRS1IRS1
Entrez,  Source
insulin receptor substrate 15490.1140.1479No
11SQLESQLE
Entrez,  Source
squalene epoxidase6340.1080.1536No
12NTF3NTF3
Entrez,  Source
neurotrophin 312910.0810.1129No
13HAS2HAS2
Entrez,  Source
hyaluronan synthase 213430.0790.1178No
14RHOBRHOB
Entrez,  Source
ras homolog gene family, member B13500.0790.1262No
15ZHX3ZHX3
Entrez,  Source
zinc fingers and homeoboxes 316520.0710.1113No
16GATA2GATA2
Entrez,  Source
GATA binding protein 217550.0690.1113No
17AGTR1AGTR1
Entrez,  Source
angiotensin II receptor, type 120900.0600.0927No
18IL4RIL4R
Entrez,  Source
interleukin 4 receptor21300.0590.0964No
19ADMADM
Entrez,  Source
adrenomedullin21890.0580.0984No
20CRKLCRKL
Entrez,  Source
v-crk sarcoma virus CT10 oncogene homolog (avian)-like23360.0550.0935No
21YY1YY1
Entrez,  Source
YY1 transcription factor24290.0530.0924No
22GREM1GREM1
Entrez,  Source
gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)24340.0530.0981No
23KLF9KLF9
Entrez,  Source
Kruppel-like factor 926890.0480.0842No
24TWIST1TWIST1
Entrez,  Source
twist homolog 1 (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) (Drosophila)27280.0470.0866No
25PDGFRAPDGFRA
Entrez,  Source
platelet-derived growth factor receptor, alpha polypeptide28440.0450.0830No
26DUSP11DUSP11
Entrez,  Source
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)32740.0390.0548No
27NFIL3NFIL3
Entrez,  Source
nuclear factor, interleukin 3 regulated36610.0330.0292No
28MAP1BMAP1B
Entrez,  Source
microtubule-associated protein 1B37000.0330.0300No
29MAPK6MAPK6
Entrez,  Source
mitogen-activated protein kinase 637050.0320.0333No
30UNGUNG
Entrez,  Source
uracil-DNA glycosylase38870.0300.0229No
31CEBPDCEBPD
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), delta42220.0260.0005No
32JUNDJUND
Entrez,  Source
jun D proto-oncogene43210.024-0.0042No
33STK38STK38
Entrez,  Source
serine/threonine kinase 3843770.023-0.0058No
34ANKRD15ANKRD15
Entrez,  Source
ankyrin repeat domain 1543890.023-0.0040No
35EIF4EEIF4E
Entrez,  Source
eukaryotic translation initiation factor 4E45110.022-0.0108No
36FBXO46FBXO46
Entrez,  Source
F-box protein 4646620.020-0.0199No
37GNEGNE
Entrez,  Source
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase47300.019-0.0228No
38RAF1RAF1
Entrez,  Source
v-raf-1 murine leukemia viral oncogene homolog 148110.018-0.0268No
39PRKCBP1PRKCBP1
Entrez,  Source
protein kinase C binding protein 148310.018-0.0262No
40UBE2NUBE2N
Entrez,  Source
ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)48640.018-0.0267No
41EDD1EDD1
Entrez,  Source
E3 ubiquitin protein ligase, HECT domain containing, 148780.018-0.0257No
42TPST1TPST1
Entrez,  Source
tyrosylprotein sulfotransferase 149090.017-0.0260No
43TARDBPTARDBP
Entrez,  Source
TAR DNA binding protein49500.017-0.0272No
44ATP6V1B2ATP6V1B2
Entrez,  Source
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B250110.016-0.0300No
45TGIFTGIF
Entrez,  Source
TGFB-induced factor (TALE family homeobox)50500.015-0.0312No
46ADNPADNP
Entrez,  Source
activity-dependent neuroprotector52200.013-0.0425No
47FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES52690.013-0.0447No
48ZFP36L2ZFP36L2
Entrez,  Source
zinc finger protein 36, C3H type-like 253500.012-0.0494No
49RNF4RNF4
Entrez,  Source
ring finger protein 453550.012-0.0484No
50RND3RND3
Entrez,  Source
Rho family GTPase 353570.012-0.0471No
51BRD8BRD8
Entrez,  Source
bromodomain containing 853770.012-0.0473No
52TNFRSF1ATNFRSF1A
Entrez,  Source
tumor necrosis factor receptor superfamily, member 1A54750.010-0.0535No
53USP1USP1
Entrez,  Source
ubiquitin specific peptidase 155170.010-0.0554No
54RAB1ARAB1A
Entrez,  Source
RAB1A, member RAS oncogene family55610.009-0.0576No
55NFYBNFYB
Entrez,  Source
nuclear transcription factor Y, beta56440.009-0.0629No
56TSPAN5TSPAN5
Entrez,  Source
tetraspanin 557100.008-0.0670No
57DDX3XDDX3X
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked57280.008-0.0674No
58SPOPSPOP
Entrez,  Source
speckle-type POZ protein57340.008-0.0669No
59SERTAD2SERTAD2
Entrez,  Source
SERTA domain containing 257840.007-0.0699No
60NFE2L2NFE2L2
Entrez,  Source
nuclear factor (erythroid-derived 2)-like 258110.007-0.0711No
61GTF2E1GTF2E1
Entrez,  Source
general transcription factor IIE, polypeptide 1, alpha 56kDa58780.006-0.0755No
62TMEM97TMEM97
Entrez,  Source
transmembrane protein 9760350.004-0.0868No
63PGRMC2PGRMC2
Entrez,  Source
progesterone receptor membrane component 260400.004-0.0867No
64PUM2PUM2
Entrez,  Source
pumilio homolog 2 (Drosophila)60770.004-0.0890No
65COILCOIL
Entrez,  Source
coilin61380.003-0.0931No
66FUSFUS
Entrez,  Source
fusion (involved in t(12;16) in malignant liposarcoma)61870.003-0.0965No
67PTDSRPTDSR
Entrez,  Source
phosphatidylserine receptor62510.002-0.1011No
68FGF5FGF5
Entrez,  Source
fibroblast growth factor 562860.001-0.1035No
69PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa63050.001-0.1047No
70CCNG1CCNG1
Entrez,  Source
cyclin G163220.001-0.1058No
71ARF6ARF6
Entrez,  Source
ADP-ribosylation factor 66594-0.002-0.1262No
72USP10USP10
Entrez,  Source
ubiquitin specific peptidase 106609-0.002-0.1270No
73TUBGCP3TUBGCP3
Entrez,  Source
tubulin, gamma complex associated protein 36657-0.003-0.1303No
74MAPK14MAPK14
Entrez,  Source
mitogen-activated protein kinase 146688-0.003-0.1322No
75DDX17DDX17
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 176719-0.003-0.1342No
76BLCAPBLCAP
Entrez,  Source
bladder cancer associated protein7002-0.006-0.1549No
77NUP153NUP153
Entrez,  Source
nucleoporin 153kDa7107-0.007-0.1621No
78ATP2A2ATP2A2
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, slow twitch 27144-0.007-0.1640No
79NR2F2NR2F2
Entrez,  Source
nuclear receptor subfamily 2, group F, member 27287-0.009-0.1738No
80CASP3CASP3
Entrez,  Source
caspase 3, apoptosis-related cysteine peptidase7301-0.009-0.1738No
81DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 17336-0.009-0.1754No
82SS18SS18
Entrez,  Source
synovial sarcoma translocation, chromosome 187348-0.009-0.1753No
83RAB11ARAB11A
Entrez,  Source
RAB11A, member RAS oncogene family7378-0.009-0.1764No
84PMP22PMP22
Entrez,  Source
peripheral myelin protein 227414-0.010-0.1780No
85XPO1XPO1
Entrez,  Source
exportin 1 (CRM1 homolog, yeast)7439-0.010-0.1787No
86PPAP2BPPAP2B
Entrez,  Source
phosphatidic acid phosphatase type 2B7532-0.011-0.1845No
87PITPNBPITPNB
Entrez,  Source
phosphatidylinositol transfer protein, beta7840-0.014-0.2062No
88ARHGEF7ARHGEF7
Entrez,  Source
Rho guanine nucleotide exchange factor (GEF) 77877-0.014-0.2073No
89CLINT1CLINT1
Entrez,  Source
clathrin interactor 18119-0.017-0.2237No
90RAB14RAB14
Entrez,  Source
RAB14, member RAS oncogene family8275-0.018-0.2334No
91KPNA2KPNA2
Entrez,  Source
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)8310-0.019-0.2339No
92MTMR3MTMR3
Entrez,  Source
myotubularin related protein 38338-0.019-0.2338No
93EDG2EDG2
Entrez,  Source
endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 28571-0.022-0.2490No
94THUMPD1THUMPD1
Entrez,  Source
THUMP domain containing 18574-0.022-0.2467No
95UBE2G1UBE2G1
Entrez,  Source
ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)8739-0.023-0.2565No
96PPP2R1BPPP2R1B
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform9012-0.026-0.2742No
97DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A9041-0.026-0.2734No
98NASPNASP
Entrez,  Source
nuclear autoantigenic sperm protein (histone-binding)9143-0.027-0.2780No
99STX3STX3
Entrez,  Source
syntaxin 39160-0.028-0.2761No
100NDUFV2NDUFV2
Entrez,  Source
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa9181-0.028-0.2745No
101TOP2ATOP2A
Entrez,  Source
topoisomerase (DNA) II alpha 170kDa9337-0.029-0.2830No
102RBM5RBM5
Entrez,  Source
RNA binding motif protein 59365-0.030-0.2817No
103HMGA2HMGA2
Entrez,  Source
high mobility group AT-hook 29527-0.032-0.2904No
104AURKAAURKA
Entrez,  Source
aurora kinase A9667-0.034-0.2971No
105TRIP10TRIP10
Entrez,  Source
thyroid hormone receptor interactor 109804-0.035-0.3035No
106NCOA3NCOA3
Entrez,  Source
nuclear receptor coactivator 39861-0.036-0.3038No
107CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)10156-0.039-0.3217No
108PTPN1PTPN1
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 110210-0.040-0.3213No
109UBTFUBTF
Entrez,  Source
upstream binding transcription factor, RNA polymerase I10220-0.040-0.3175No
110SLC20A2SLC20A2
Entrez,  Source
solute carrier family 20 (phosphate transporter), member 210283-0.040-0.3177No
111MLXMLX
Entrez,  Source
MAX-like protein X10350-0.041-0.3181No
112CYR61CYR61
Entrez,  Source
cysteine-rich, angiogenic inducer, 6110367-0.041-0.3147No
113CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase10368-0.041-0.3100No
114DR1DR1
Entrez,  Source
down-regulator of transcription 1, TBP-binding (negative cofactor 2)10653-0.046-0.3265No
115CDR2CDR2
Entrez,  Source
cerebellar degeneration-related protein 2, 62kDa10906-0.050-0.3400Yes
116PLEKHC1PLEKHC1
Entrez,  Source
pleckstrin homology domain containing, family C (with FERM domain) member 110973-0.051-0.3394Yes
117SPRED2SPRED2
Entrez,  Source
sprouty-related, EVH1 domain containing 210977-0.051-0.3339Yes
118STRN3STRN3
Entrez,  Source
striatin, calmodulin binding protein 311023-0.051-0.3316Yes
119PPP1R12APPP1R12A
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 12A11026-0.051-0.3260Yes
120SIAH2SIAH2
Entrez,  Source
seven in absentia homolog 2 (Drosophila)11053-0.052-0.3221Yes
121CNOT2CNOT2
Entrez,  Source
CCR4-NOT transcription complex, subunit 211214-0.055-0.3281Yes
122TAF11TAF11
Entrez,  Source
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa11247-0.056-0.3243Yes
123PRKCDPRKCD
Entrez,  Source
protein kinase C, delta11467-0.060-0.3342Yes
124MARCKSMARCKS
Entrez,  Source
myristoylated alanine-rich protein kinase C substrate11501-0.060-0.3299Yes
125REV3LREV3L
Entrez,  Source
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)11512-0.061-0.3239Yes
126LBRLBR
Entrez,  Source
lamin B receptor11583-0.062-0.3222Yes
127DICER1DICER1
Entrez,  Source
Dicer1, Dcr-1 homolog (Drosophila)11587-0.062-0.3155Yes
128ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein11598-0.062-0.3093Yes
129PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 211607-0.063-0.3028Yes
130CBX3CBX3
Entrez,  Source
chromobox homolog 3 (HP1 gamma homolog, Drosophila)11686-0.064-0.3016Yes
131STXBP3STXBP3
Entrez,  Source
syntaxin binding protein 311792-0.067-0.3020Yes
132SMAD3SMAD3
Entrez,  Source
SMAD, mothers against DPP homolog 3 (Drosophila)11928-0.071-0.3043Yes
133NAP1L1NAP1L1
Entrez,  Source
nucleosome assembly protein 1-like 111929-0.071-0.2964Yes
134TRIM32TRIM32
Entrez,  Source
tripartite motif-containing 3212008-0.073-0.2942Yes
135BMPR1ABMPR1A
Entrez,  Source
bone morphogenetic protein receptor, type IA12130-0.077-0.2947Yes
136FADDFADD
Entrez,  Source
Fas (TNFRSF6)-associated via death domain12156-0.078-0.2879Yes
137AMD1AMD1
Entrez,  Source
adenosylmethionine decarboxylase 112226-0.080-0.2842Yes
138PARP1PARP1
Entrez,  Source
poly (ADP-ribose) polymerase family, member 112319-0.083-0.2818Yes
139VEGFCVEGFC
Entrez,  Source
vascular endothelial growth factor C12416-0.088-0.2793Yes
140EMP1EMP1
Entrez,  Source
epithelial membrane protein 112503-0.092-0.2755Yes
141PHC2PHC2
Entrez,  Source
polyhomeotic homolog 2 (Drosophila)12525-0.093-0.2667Yes
142STX7STX7
Entrez,  Source
syntaxin 712526-0.093-0.2563Yes
143UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase12641-0.099-0.2539Yes
144MAT2AMAT2A
Entrez,  Source
methionine adenosyltransferase II, alpha12685-0.102-0.2457Yes
145PODXLPODXL
Entrez,  Source
podocalyxin-like12713-0.104-0.2361Yes
146WEE1WEE1
Entrez,  Source
WEE1 homolog (S. pombe)12787-0.110-0.2293Yes
147CITED2CITED2
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 212899-0.121-0.2242Yes
148KIF2AKIF2A
Entrez,  Source
kinesin heavy chain member 2A12962-0.127-0.2147Yes
149ID2ID2
Entrez,  Source
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein13084-0.146-0.2074Yes
150RRAS2RRAS2
Entrez,  Source
related RAS viral (r-ras) oncogene homolog 213088-0.147-0.1912Yes
151RUNX1RUNX1
Entrez,  Source
runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)13119-0.153-0.1764Yes
152METMET
Entrez,  Source
met proto-oncogene (hepatocyte growth factor receptor)13148-0.161-0.1605Yes
153TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)13153-0.163-0.1426Yes
154ITGA6ITGA6
Entrez,  Source
integrin, alpha 613167-0.169-0.1246Yes
155CCNA2CCNA2
Entrez,  Source
cyclin A213194-0.185-0.1059Yes
156SCHIP1SCHIP1
Entrez,  Source
schwannomin interacting protein 113195-0.185-0.0851Yes
157PDE4BPDE4B
Entrez,  Source
phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)13271-0.241-0.0638Yes
158CTGFCTGF
Entrez,  Source
connective tissue growth factor13284-0.263-0.0353Yes
159GNAI1GNAI1
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 113318-0.3540.0018Yes
Table: GSEA details [plain text format]



Fig 2: UVC_HIGH_ALL_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: UVC_HIGH_ALL_DN: Random ES distribution   
Gene set null distribution of ES for UVC_HIGH_ALL_DN