Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_24h_versus_single_gel_24h.class.cls
#double_gel_24h_versus_single_gel_24h_repos
Phenotypeclass.cls#double_gel_24h_versus_single_gel_24h_repos
Upregulated in classsingle_gel_24h
GeneSetUVC_TTD_ALL_DN
Enrichment Score (ES)-0.41741383
Normalized Enrichment Score (NES)-1.8396299
Nominal p-value0.0
FDR q-value0.12163367
FWER p-Value0.917
Table: GSEA Results Summary



Fig 1: Enrichment plot: UVC_TTD_ALL_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CXCL12CXCL12
Entrez,  Source
chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)1050.1750.0115No
2BHLHB2BHLHB2
Entrez,  Source
basic helix-loop-helix domain containing, class B, 21640.1550.0244No
3CREBBPCREBBP
Entrez,  Source
CREB binding protein (Rubinstein-Taybi syndrome)1790.1520.0403No
4IGF2BP3IGF2BP3
Entrez,  Source
insulin-like growth factor 2 mRNA binding protein 31990.1490.0554No
5IFRD1IFRD1
Entrez,  Source
interferon-related developmental regulator 12630.1400.0662No
6SLIT1SLIT1
Entrez,  Source
slit homolog 1 (Drosophila)5710.1120.0554No
7MID1MID1
Entrez,  Source
midline 1 (Opitz/BBB syndrome)7310.1030.0548No
8HAS2HAS2
Entrez,  Source
hyaluronan synthase 213430.0790.0172No
9MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)14110.0770.0208No
10HNRPDLHNRPDL
Entrez,  Source
heterogeneous nuclear ribonucleoprotein D-like15820.0730.0160No
11ZHX3ZHX3
Entrez,  Source
zinc fingers and homeoboxes 316520.0710.0186No
12SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 118050.0670.0146No
13KLF10KLF10
Entrez,  Source
Kruppel-like factor 1018370.0670.0197No
14AMPHAMPH
Entrez,  Source
amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen)18570.0660.0256No
15FGF2FGF2
Entrez,  Source
fibroblast growth factor 2 (basic)22530.0560.0019No
16TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 222820.0560.0060No
17GPR176GPR176
Entrez,  Source
G protein-coupled receptor 17623540.0540.0066No
18PARD3PARD3
Entrez,  Source
par-3 partitioning defective 3 homolog (C. elegans)24210.0530.0076No
19CTBP2CTBP2
Entrez,  Source
C-terminal binding protein 226350.049-0.0031No
20EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)27160.048-0.0039No
21CRY1CRY1
Entrez,  Source
cryptochrome 1 (photolyase-like)27400.047-0.0004No
22MGAT5MGAT5
Entrez,  Source
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase28030.0460.0001No
23COL5A2COL5A2
Entrez,  Source
collagen, type V, alpha 231690.041-0.0231No
24ENC1ENC1
Entrez,  Source
ectodermal-neural cortex (with BTB-like domain)31960.040-0.0206No
25CAP2CAP2
Entrez,  Source
CAP, adenylate cyclase-associated protein, 2 (yeast)31980.040-0.0162No
26MARCH7MARCH7
Entrez,  Source
membrane-associated ring finger (C3HC4) 732170.040-0.0132No
27RGS7RGS7
Entrez,  Source
regulator of G-protein signalling 735980.034-0.0382No
28MAPK6MAPK6
Entrez,  Source
mitogen-activated protein kinase 637050.032-0.0426No
29PEX14PEX14
Entrez,  Source
peroxisomal biogenesis factor 1439010.030-0.0541No
30ARNT2ARNT2
Entrez,  Source
aryl-hydrocarbon receptor nuclear translocator 240500.028-0.0623No
31PTPN12PTPN12
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 1240860.027-0.0619No
32CUTL1CUTL1
Entrez,  Source
cut-like 1, CCAAT displacement protein (Drosophila)42350.025-0.0703No
33MDN1MDN1
Entrez,  Source
MDN1, midasin homolog (yeast)43160.024-0.0736No
34EIF4EEIF4E
Entrez,  Source
eukaryotic translation initiation factor 4E45110.022-0.0859No
35CBLBCBLB
Entrez,  Source
Cas-Br-M (murine) ecotropic retroviral transforming sequence b45500.021-0.0864No
36ITSN1ITSN1
Entrez,  Source
intersectin 1 (SH3 domain protein)45840.021-0.0866No
37ORC2LORC2L
Entrez,  Source
origin recognition complex, subunit 2-like (yeast)47980.019-0.1007No
38DLC1DLC1
Entrez,  Source
deleted in liver cancer 148240.018-0.1006No
39PRKCBP1PRKCBP1
Entrez,  Source
protein kinase C binding protein 148310.018-0.0990No
40GULP1GULP1
Entrez,  Source
GULP, engulfment adaptor PTB domain containing 148450.018-0.0980No
41PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha48830.018-0.0988No
42PHLPPPHLPP
Entrez,  Source
PH domain and leucine rich repeat protein phosphatase50730.015-0.1115No
43FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES52690.013-0.1248No
44PPP2R2APPP2R2A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform54480.011-0.1371No
45HOMER1HOMER1
Entrez,  Source
homer homolog 1 (Drosophila)55980.009-0.1474No
46RBM16RBM16
Entrez,  Source
RNA binding motif protein 1656480.009-0.1502No
47TSPAN5TSPAN5
Entrez,  Source
tetraspanin 557100.008-0.1539No
48MYST3MYST3
Entrez,  Source
MYST histone acetyltransferase (monocytic leukemia) 357160.008-0.1534No
49RSNRSN
Entrez,  Source
restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)57290.008-0.1535No
50SPOPSPOP
Entrez,  Source
speckle-type POZ protein57340.008-0.1530No
51PTPRMPTPRM
Entrez,  Source
protein tyrosine phosphatase, receptor type, M57680.007-0.1547No
52GBE1GBE1
Entrez,  Source
glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV)58750.006-0.1621No
53ACVR2AACVR2A
Entrez,  Source
activin A receptor, type IIA59570.005-0.1677No
54ATF2ATF2
Entrez,  Source
activating transcription factor 260210.004-0.1719No
55PUM2PUM2
Entrez,  Source
pumilio homolog 2 (Drosophila)60770.004-0.1757No
56RBM39RBM39
Entrez,  Source
RNA binding motif protein 3961070.004-0.1775No
57FGF5FGF5
Entrez,  Source
fibroblast growth factor 562860.001-0.1908No
58PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa63050.001-0.1920No
59GTF2F2GTF2F2
Entrez,  Source
general transcription factor IIF, polypeptide 2, 30kDa63780.000-0.1975No
60TUBGCP3TUBGCP3
Entrez,  Source
tubulin, gamma complex associated protein 36657-0.003-0.2183No
61ZNF148ZNF148
Entrez,  Source
zinc finger protein 1486724-0.003-0.2229No
62MYO1BMYO1B
Entrez,  Source
myosin IB6819-0.004-0.2296No
63SEPT9SEPT9
Entrez,  Source
septin 96891-0.005-0.2345No
64ZNF292ZNF292
Entrez,  Source
zinc finger protein 2926983-0.005-0.2408No
65CEP170CEP170
Entrez,  Source
centrosomal protein 170kDa7086-0.006-0.2478No
66NUP153NUP153
Entrez,  Source
nucleoporin 153kDa7107-0.007-0.2486No
67AFAPAFAP
Entrez,  Source
-7125-0.007-0.2491No
68ABI1ABI1
Entrez,  Source
abl-interactor 17128-0.007-0.2485No
69TDRD3TDRD3
Entrez,  Source
tudor domain containing 37165-0.007-0.2504No
70DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 17336-0.009-0.2623No
71ACVR1ACVR1
Entrez,  Source
activin A receptor, type I7360-0.009-0.2630No
72MAP2K4MAP2K4
Entrez,  Source
mitogen-activated protein kinase kinase 47416-0.010-0.2661No
73CDC42BPACDC42BPA
Entrez,  Source
CDC42 binding protein kinase alpha (DMPK-like)7499-0.010-0.2712No
74PPAP2BPPAP2B
Entrez,  Source
phosphatidic acid phosphatase type 2B7532-0.011-0.2724No
75ARIH1ARIH1
Entrez,  Source
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)7627-0.012-0.2782No
76ATRXATRX
Entrez,  Source
alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)7684-0.012-0.2811No
77XRCC4XRCC4
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 47798-0.014-0.2882No
78ARHGEF7ARHGEF7
Entrez,  Source
Rho guanine nucleotide exchange factor (GEF) 77877-0.014-0.2925No
79FLNBFLNB
Entrez,  Source
filamin B, beta (actin binding protein 278)7935-0.015-0.2951No
80MSH3MSH3
Entrez,  Source
mutS homolog 3 (E. coli)7967-0.015-0.2958No
81STK39STK39
Entrez,  Source
serine threonine kinase 39 (STE20/SPS1 homolog, yeast)8189-0.018-0.3106No
82MTMR3MTMR3
Entrez,  Source
myotubularin related protein 38338-0.019-0.3197No
83NUP98NUP98
Entrez,  Source
nucleoporin 98kDa8404-0.020-0.3224No
84MGLLMGLL
Entrez,  Source
monoglyceride lipase8545-0.021-0.3307No
85EDG2EDG2
Entrez,  Source
endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 28571-0.022-0.3302No
86ZMYND11ZMYND11
Entrez,  Source
zinc finger, MYND domain containing 118725-0.023-0.3392No
87ATP2B1ATP2B1
Entrez,  Source
ATPase, Ca++ transporting, plasma membrane 18980-0.026-0.3556No
88DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A9041-0.026-0.3572No
89MBNL1MBNL1
Entrez,  Source
muscleblind-like (Drosophila)9251-0.029-0.3699No
90PKN2PKN2
Entrez,  Source
protein kinase N29258-0.029-0.3671No
91DPYDDPYD
Entrez,  Source
dihydropyrimidine dehydrogenase9279-0.029-0.3654No
92CEP350CEP350
Entrez,  Source
centrosomal protein 350kDa9340-0.029-0.3667No
93PTPN2PTPN2
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 29568-0.032-0.3803No
94NFIBNFIB
Entrez,  Source
nuclear factor I/B9610-0.033-0.3798No
95MNAT1MNAT1
Entrez,  Source
menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)9616-0.033-0.3765No
96NIPBLNIPBL
Entrez,  Source
Nipped-B homolog (Drosophila)9627-0.033-0.3736No
97OGTOGT
Entrez,  Source
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)9640-0.033-0.3708No
98PRIM2APRIM2A
Entrez,  Source
primase, polypeptide 2A, 58kDa9718-0.034-0.3728No
99FUBP1FUBP1
Entrez,  Source
far upstream element (FUSE) binding protein 19728-0.034-0.3697No
100NCOA3NCOA3
Entrez,  Source
nuclear receptor coactivator 39861-0.036-0.3757No
101ATXN1ATXN1
Entrez,  Source
ataxin 19911-0.036-0.3754No
102WDR7WDR7
Entrez,  Source
WD repeat domain 79968-0.037-0.3756No
103GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta10151-0.039-0.3850No
104SKAP2SKAP2
Entrez,  Source
src kinase associated phosphoprotein 210200-0.039-0.3843No
105CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase10368-0.041-0.3923No
106ZRF1ZRF1
Entrez,  Source
zuotin related factor 110439-0.042-0.3929No
107FARS2FARS2
Entrez,  Source
phenylalanine-tRNA synthetase 2 (mitochondrial)10489-0.043-0.3918No
108GNAQGNAQ
Entrez,  Source
guanine nucleotide binding protein (G protein), q polypeptide10825-0.048-0.4118Yes
109TCF12TCF12
Entrez,  Source
transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)10869-0.049-0.4096Yes
110PLEKHC1PLEKHC1
Entrez,  Source
pleckstrin homology domain containing, family C (with FERM domain) member 110973-0.051-0.4118Yes
111STRN3STRN3
Entrez,  Source
striatin, calmodulin binding protein 311023-0.051-0.4098Yes
112PPP1R12APPP1R12A
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 12A11026-0.051-0.4042Yes
113BARD1BARD1
Entrez,  Source
BRCA1 associated RING domain 111085-0.053-0.4028Yes
114SERPINB2SERPINB2
Entrez,  Source
serpin peptidase inhibitor, clade B (ovalbumin), member 211162-0.054-0.4025Yes
115CNOT2CNOT2
Entrez,  Source
CCR4-NOT transcription complex, subunit 211214-0.055-0.4002Yes
116MTF2MTF2
Entrez,  Source
metal response element binding transcription factor 211313-0.057-0.4013Yes
117REV3LREV3L
Entrez,  Source
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)11512-0.061-0.4096Yes
118CNOT4CNOT4
Entrez,  Source
CCR4-NOT transcription complex, subunit 411569-0.062-0.4069Yes
119ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein11598-0.062-0.4021Yes
120PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 211607-0.063-0.3958Yes
121FUT8FUT8
Entrez,  Source
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)11656-0.064-0.3923Yes
122UBL3UBL3
Entrez,  Source
ubiquitin-like 311808-0.068-0.3962Yes
123SLC4A7SLC4A7
Entrez,  Source
solute carrier family 4, sodium bicarbonate cotransporter, member 711826-0.068-0.3899Yes
124SPBC25SPBC25
Entrez,  Source
spindle pole body component 25 homolog (S. cerevisiae)11828-0.068-0.3824Yes
125PCTK2PCTK2
Entrez,  Source
PCTAIRE protein kinase 211883-0.070-0.3788Yes
126SMAD3SMAD3
Entrez,  Source
SMAD, mothers against DPP homolog 3 (Drosophila)11928-0.071-0.3743Yes
127CLASP2CLASP2
Entrez,  Source
cytoplasmic linker associated protein 211968-0.072-0.3692Yes
128PTPRKPTPRK
Entrez,  Source
protein tyrosine phosphatase, receptor type, K11989-0.073-0.3627Yes
129TMEM23TMEM23
Entrez,  Source
transmembrane protein 2312115-0.076-0.3637Yes
130IL1RAPIL1RAP
Entrez,  Source
interleukin 1 receptor accessory protein12123-0.077-0.3556Yes
131PARGPARG
Entrez,  Source
poly (ADP-ribose) glycohydrolase12259-0.081-0.3568Yes
132VEGFCVEGFC
Entrez,  Source
vascular endothelial growth factor C12416-0.088-0.3589Yes
133CASKCASK
Entrez,  Source
calcium/calmodulin-dependent serine protein kinase (MAGUK family)12444-0.088-0.3511Yes
134LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog12577-0.095-0.3505Yes
135TRIOTRIO
Entrez,  Source
triple functional domain (PTPRF interacting)12578-0.095-0.3399Yes
136UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase12641-0.099-0.3336Yes
137STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)12679-0.101-0.3251Yes
138BMP2KBMP2K
Entrez,  Source
BMP2 inducible kinase12687-0.102-0.3143Yes
139PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 512904-0.122-0.3171Yes
140SIPA1L1SIPA1L1
Entrez,  Source
signal-induced proliferation-associated 1 like 112930-0.125-0.3051Yes
141KIF2AKIF2A
Entrez,  Source
kinesin heavy chain member 2A12962-0.127-0.2933Yes
142NRG1NRG1
Entrez,  Source
neuregulin 113047-0.140-0.2842Yes
143RRAS2RRAS2
Entrez,  Source
related RAS viral (r-ras) oncogene homolog 213088-0.147-0.2708Yes
144RUNX1RUNX1
Entrez,  Source
runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)13119-0.153-0.2561Yes
145ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 213146-0.160-0.2403Yes
146TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)13153-0.163-0.2226Yes
147SYNJ2SYNJ2
Entrez,  Source
synaptojanin 213158-0.165-0.2045Yes
148CLASP1CLASP1
Entrez,  Source
cytoplasmic linker associated protein 113168-0.170-0.1863Yes
149SCHIP1SCHIP1
Entrez,  Source
schwannomin interacting protein 113195-0.185-0.1677Yes
150CTGFCTGF
Entrez,  Source
connective tissue growth factor13284-0.263-0.1452Yes
151CCND1CCND1
Entrez,  Source
cyclin D113302-0.295-0.1136Yes
152F3F3
Entrez,  Source
coagulation factor III (thromboplastin, tissue factor)13312-0.331-0.0775Yes
153GNAI1GNAI1
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 113318-0.354-0.0385Yes
154PPP2R3APPP2R3A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha13320-0.3620.0017Yes
Table: GSEA details [plain text format]



Fig 2: UVC_TTD_ALL_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: UVC_TTD_ALL_DN: Random ES distribution   
Gene set null distribution of ES for UVC_TTD_ALL_DN