Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_24h_versus_single_gel_24h.class.cls
#double_gel_24h_versus_single_gel_24h_repos
Phenotypeclass.cls#double_gel_24h_versus_single_gel_24h_repos
Upregulated in classsingle_gel_24h
GeneSetUVC_XPCS_8HR_DN
Enrichment Score (ES)-0.34646988
Normalized Enrichment Score (NES)-1.5547378
Nominal p-value0.0
FDR q-value0.25062758
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: UVC_XPCS_8HR_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1IGF1RIGF1R
Entrez,  Source
insulin-like growth factor 1 receptor760.1890.0151No
2CXCL12CXCL12
Entrez,  Source
chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)1050.1750.0323No
3CREBBPCREBBP
Entrez,  Source
CREB binding protein (Rubinstein-Taybi syndrome)1790.1520.0435No
4IGF2BP3IGF2BP3
Entrez,  Source
insulin-like growth factor 2 mRNA binding protein 31990.1490.0586No
5DUSP5DUSP5
Entrez,  Source
dual specificity phosphatase 52060.1480.0745No
6IFRD1IFRD1
Entrez,  Source
interferon-related developmental regulator 12630.1400.0857No
7SLKSLK
Entrez,  Source
STE20-like kinase (yeast)5650.1120.0753No
8MID1MID1
Entrez,  Source
midline 1 (Opitz/BBB syndrome)7310.1030.0741No
9ACSL3ACSL3
Entrez,  Source
acyl-CoA synthetase long-chain family member 39060.0950.0714No
10CENTB2CENTB2
Entrez,  Source
centaurin, beta 213350.0790.0476No
11MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)14110.0770.0504No
12HNRPDLHNRPDL
Entrez,  Source
heterogeneous nuclear ribonucleoprotein D-like15820.0730.0456No
13ZHX3ZHX3
Entrez,  Source
zinc fingers and homeoboxes 316520.0710.0482No
14SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 118050.0670.0440No
15RAGERAGE
Entrez,  Source
renal tumor antigen20080.0620.0356No
16FGF2FGF2
Entrez,  Source
fibroblast growth factor 2 (basic)22530.0560.0232No
17TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 222820.0560.0273No
18PARD3PARD3
Entrez,  Source
par-3 partitioning defective 3 homolog (C. elegans)24210.0530.0227No
19CTBP2CTBP2
Entrez,  Source
C-terminal binding protein 226350.0490.0119No
20EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)27160.0480.0111No
21KLF6KLF6
Entrez,  Source
Kruppel-like factor 629600.044-0.0025No
22SLIT2SLIT2
Entrez,  Source
slit homolog 2 (Drosophila)30060.043-0.0012No
23RGS7RGS7
Entrez,  Source
regulator of G-protein signalling 735980.034-0.0424No
24CDH2CDH2
Entrez,  Source
cadherin 2, type 1, N-cadherin (neuronal)37140.032-0.0475No
25PLCB4PLCB4
Entrez,  Source
phospholipase C, beta 438600.030-0.0552No
26UBE2D2UBE2D2
Entrez,  Source
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)39520.029-0.0589No
27PTPN12PTPN12
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 1240860.027-0.0660No
28GMPSGMPS
Entrez,  Source
guanine monphosphate synthetase41350.026-0.0667No
29MAP2K1MAP2K1
Entrez,  Source
mitogen-activated protein kinase kinase 141720.026-0.0666No
30CUTL1CUTL1
Entrez,  Source
cut-like 1, CCAAT displacement protein (Drosophila)42350.025-0.0685No
31PEX3PEX3
Entrez,  Source
peroxisomal biogenesis factor 342630.025-0.0678No
32MDN1MDN1
Entrez,  Source
MDN1, midasin homolog (yeast)43160.024-0.0690No
33E2F5E2F5
Entrez,  Source
E2F transcription factor 5, p130-binding43710.024-0.0705No
34PJA2PJA2
Entrez,  Source
praja 2, RING-H2 motif containing44880.022-0.0769No
35EIF4EEIF4E
Entrez,  Source
eukaryotic translation initiation factor 4E45110.022-0.0762No
36CBLBCBLB
Entrez,  Source
Cas-Br-M (murine) ecotropic retroviral transforming sequence b45500.021-0.0767No
37ITSN1ITSN1
Entrez,  Source
intersectin 1 (SH3 domain protein)45840.021-0.0769No
38TIAM1TIAM1
Entrez,  Source
T-cell lymphoma invasion and metastasis 146630.020-0.0807No
39ORC2LORC2L
Entrez,  Source
origin recognition complex, subunit 2-like (yeast)47980.019-0.0888No
40DLC1DLC1
Entrez,  Source
deleted in liver cancer 148240.018-0.0887No
41PRKCBP1PRKCBP1
Entrez,  Source
protein kinase C binding protein 148310.018-0.0871No
42CREB3L2CREB3L2
Entrez,  Source
cAMP responsive element binding protein 3-like 248340.018-0.0853No
43EDD1EDD1
Entrez,  Source
E3 ubiquitin protein ligase, HECT domain containing, 148780.018-0.0866No
44PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha48830.018-0.0850No
45XPO6XPO6
Entrez,  Source
exportin 649170.017-0.0856No
46PHLPPPHLPP
Entrez,  Source
PH domain and leucine rich repeat protein phosphatase50730.015-0.0957No
47SLC7A1SLC7A1
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 151880.014-0.1028No
48FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES52690.013-0.1075No
49RAD23BRAD23B
Entrez,  Source
RAD23 homolog B (S. cerevisiae)53660.012-0.1135No
50HOMER1HOMER1
Entrez,  Source
homer homolog 1 (Drosophila)55980.009-0.1300No
51RBM16RBM16
Entrez,  Source
RNA binding motif protein 1656480.009-0.1328No
52TSPAN5TSPAN5
Entrez,  Source
tetraspanin 557100.008-0.1366No
53MYST3MYST3
Entrez,  Source
MYST histone acetyltransferase (monocytic leukemia) 357160.008-0.1361No
54RSNRSN
Entrez,  Source
restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)57290.008-0.1362No
55ATRNATRN
Entrez,  Source
attractin58690.006-0.1461No
56GBE1GBE1
Entrez,  Source
glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV)58750.006-0.1458No
57ATF2ATF2
Entrez,  Source
activating transcription factor 260210.004-0.1564No
58PUM2PUM2
Entrez,  Source
pumilio homolog 2 (Drosophila)60770.004-0.1601No
59FGF5FGF5
Entrez,  Source
fibroblast growth factor 562860.001-0.1758No
60PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa63050.001-0.1770No
61ADARB1ADARB1
Entrez,  Source
adenosine deaminase, RNA-specific, B1 (RED1 homolog rat)63390.001-0.1794No
62GTF2F2GTF2F2
Entrez,  Source
general transcription factor IIF, polypeptide 2, 30kDa63780.000-0.1822No
63NUMBNUMB
Entrez,  Source
numb homolog (Drosophila)6445-0.000-0.1872No
64TUBGCP3TUBGCP3
Entrez,  Source
tubulin, gamma complex associated protein 36657-0.003-0.2030No
65RAB6ARAB6A
Entrez,  Source
RAB6A, member RAS oncogene family6696-0.003-0.2056No
66ZNF148ZNF148
Entrez,  Source
zinc finger protein 1486724-0.003-0.2073No
67PICALMPICALM
Entrez,  Source
phosphatidylinositol binding clathrin assembly protein6743-0.003-0.2083No
68WWP1WWP1
Entrez,  Source
WW domain containing E3 ubiquitin protein ligase 16766-0.003-0.2096No
69MYO1BMYO1B
Entrez,  Source
myosin IB6819-0.004-0.2131No
70TRIM2TRIM2
Entrez,  Source
tripartite motif-containing 26833-0.004-0.2136No
71SEPT9SEPT9
Entrez,  Source
septin 96891-0.005-0.2175No
72CEP170CEP170
Entrez,  Source
centrosomal protein 170kDa7086-0.006-0.2315No
73AFAPAFAP
Entrez,  Source
-7125-0.007-0.2336No
74CDC2L5CDC2L5
Entrez,  Source
cell division cycle 2-like 5 (cholinesterase-related cell division controller)7141-0.007-0.2340No
75NFKB1NFKB1
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)7260-0.008-0.2420No
76NR2F2NR2F2
Entrez,  Source
nuclear receptor subfamily 2, group F, member 27287-0.009-0.2431No
77MAP2K4MAP2K4
Entrez,  Source
mitogen-activated protein kinase kinase 47416-0.010-0.2517No
78XPO1XPO1
Entrez,  Source
exportin 1 (CRM1 homolog, yeast)7439-0.010-0.2523No
79R3HDM1R3HDM1
Entrez,  Source
R3H domain containing 17477-0.010-0.2540No
80ABCE1ABCE1
Entrez,  Source
ATP-binding cassette, sub-family E (OABP), member 17480-0.010-0.2530No
81CDC42BPACDC42BPA
Entrez,  Source
CDC42 binding protein kinase alpha (DMPK-like)7499-0.010-0.2532No
82MTX2MTX2
Entrez,  Source
metaxin 27566-0.011-0.2570No
83ARIH1ARIH1
Entrez,  Source
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)7627-0.012-0.2603No
84ATRXATRX
Entrez,  Source
alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)7684-0.012-0.2631No
85XRCC4XRCC4
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 47798-0.014-0.2702No
86SONSON
Entrez,  Source
SON DNA binding protein7838-0.014-0.2717No
87ARHGEF7ARHGEF7
Entrez,  Source
Rho guanine nucleotide exchange factor (GEF) 77877-0.014-0.2730No
88THBS2THBS2
Entrez,  Source
thrombospondin 27976-0.015-0.2787No
89PCMT1PCMT1
Entrez,  Source
protein-L-isoaspartate (D-aspartate) O-methyltransferase8056-0.016-0.2829No
90MKLN1MKLN1
Entrez,  Source
muskelin 1, intracellular mediator containing kelch motifs8067-0.016-0.2819No
91STK39STK39
Entrez,  Source
serine threonine kinase 39 (STE20/SPS1 homolog, yeast)8189-0.018-0.2891No
92NUP98NUP98
Entrez,  Source
nucleoporin 98kDa8404-0.020-0.3032No
93CDS2CDS2
Entrez,  Source
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 28543-0.021-0.3114No
94MGLLMGLL
Entrez,  Source
monoglyceride lipase8545-0.021-0.3091No
95MARK3MARK3
Entrez,  Source
MAP/microtubule affinity-regulating kinase 38547-0.021-0.3068No
96NFYCNFYC
Entrez,  Source
nuclear transcription factor Y, gamma8563-0.021-0.3056No
97GLRBGLRB
Entrez,  Source
glycine receptor, beta8597-0.022-0.3057No
98GRK5GRK5
Entrez,  Source
G protein-coupled receptor kinase 58649-0.022-0.3071No
99ZMYND11ZMYND11
Entrez,  Source
zinc finger, MYND domain containing 118725-0.023-0.3102No
100OPA1OPA1
Entrez,  Source
optic atrophy 1 (autosomal dominant)8736-0.023-0.3084No
101UBE2G1UBE2G1
Entrez,  Source
ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)8739-0.023-0.3060No
102MYO9BMYO9B
Entrez,  Source
myosin IXB8864-0.025-0.3127No
103CLOCKCLOCK
Entrez,  Source
clock homolog (mouse)8909-0.025-0.3133No
104STAU2STAU2
Entrez,  Source
staufen, RNA binding protein, homolog 2 (Drosophila)8971-0.026-0.3151No
105ATP2B1ATP2B1
Entrez,  Source
ATPase, Ca++ transporting, plasma membrane 18980-0.026-0.3129No
106DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A9041-0.026-0.3145No
107NBNNBN
Entrez,  Source
nibrin9071-0.027-0.3137No
108TRIP12TRIP12
Entrez,  Source
thyroid hormone receptor interactor 129131-0.027-0.3152No
109TJP2TJP2
Entrez,  Source
tight junction protein 2 (zona occludens 2)9217-0.028-0.3185No
110MBNL1MBNL1
Entrez,  Source
muscleblind-like (Drosophila)9251-0.029-0.3179No
111PKN2PKN2
Entrez,  Source
protein kinase N29258-0.029-0.3152No
112DPYDDPYD
Entrez,  Source
dihydropyrimidine dehydrogenase9279-0.029-0.3135No
113TOP2ATOP2A
Entrez,  Source
topoisomerase (DNA) II alpha 170kDa9337-0.029-0.3146No
114CEP350CEP350
Entrez,  Source
centrosomal protein 350kDa9340-0.029-0.3115No
115DLG1DLG1
Entrez,  Source
discs, large homolog 1 (Drosophila)9446-0.031-0.3161No
116LRPPRCLRPPRC
Entrez,  Source
leucine-rich PPR-motif containing9523-0.032-0.3184No
117SMARCA2SMARCA2
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 29559-0.032-0.3175No
118PTPN2PTPN2
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 29568-0.032-0.3145No
119NIPBLNIPBL
Entrez,  Source
Nipped-B homolog (Drosophila)9627-0.033-0.3153No
120OGTOGT
Entrez,  Source
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)9640-0.033-0.3125No
121PRIM2APRIM2A
Entrez,  Source
primase, polypeptide 2A, 58kDa9718-0.034-0.3146No
122PRMT3PRMT3
Entrez,  Source
protein arginine methyltransferase 39734-0.034-0.3119No
123NPEPPSNPEPPS
Entrez,  Source
aminopeptidase puromycin sensitive9822-0.035-0.3146No
124NCOA3NCOA3
Entrez,  Source
nuclear receptor coactivator 39861-0.036-0.3136No
125APPBP2APPBP2
Entrez,  Source
amyloid beta precursor protein (cytoplasmic tail) binding protein 29965-0.037-0.3173No
126WDR7WDR7
Entrez,  Source
WD repeat domain 79968-0.037-0.3134No
127ADAM10ADAM10
Entrez,  Source
ADAM metallopeptidase domain 1010107-0.038-0.3197No
128GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta10151-0.039-0.3186No
129DOCK9DOCK9
Entrez,  Source
dedicator of cytokinesis 910296-0.041-0.3251No
130FARS2FARS2
Entrez,  Source
phenylalanine-tRNA synthetase 2 (mitochondrial)10489-0.043-0.3349No
131PTENPTEN
Entrez,  Source
phosphatase and tensin homolog (mutated in multiple advanced cancers 1)10560-0.044-0.3353No
132EPS15EPS15
Entrez,  Source
epidermal growth factor receptor pathway substrate 1510698-0.046-0.3406No
133HERC4HERC4
Entrez,  Source
hect domain and RLD 410776-0.048-0.3412Yes
134CKAP5CKAP5
Entrez,  Source
cytoskeleton associated protein 510786-0.048-0.3366Yes
135GNAQGNAQ
Entrez,  Source
guanine nucleotide binding protein (G protein), q polypeptide10825-0.048-0.3341Yes
136TCF12TCF12
Entrez,  Source
transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)10869-0.049-0.3320Yes
137PLEKHC1PLEKHC1
Entrez,  Source
pleckstrin homology domain containing, family C (with FERM domain) member 110973-0.051-0.3342Yes
138STRN3STRN3
Entrez,  Source
striatin, calmodulin binding protein 311023-0.051-0.3323Yes
139PPP1R12APPP1R12A
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 12A11026-0.051-0.3267Yes
140BARD1BARD1
Entrez,  Source
BRCA1 associated RING domain 111085-0.053-0.3254Yes
141CNOT2CNOT2
Entrez,  Source
CCR4-NOT transcription complex, subunit 211214-0.055-0.3290Yes
142TDRD7TDRD7
Entrez,  Source
tudor domain containing 711269-0.056-0.3269Yes
143PPM1BPPM1B
Entrez,  Source
protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform11331-0.058-0.3251Yes
144RASA1RASA1
Entrez,  Source
RAS p21 protein activator (GTPase activating protein) 111353-0.058-0.3204Yes
145ZFHX1BZFHX1B
Entrez,  Source
zinc finger homeobox 1b11458-0.060-0.3217Yes
146REV3LREV3L
Entrez,  Source
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)11512-0.061-0.3190Yes
147ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein11598-0.062-0.3186Yes
148CDC27CDC27
Entrez,  Source
cell division cycle 2711606-0.063-0.3122Yes
149PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 211607-0.063-0.3052Yes
150FUT8FUT8
Entrez,  Source
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)11656-0.064-0.3018Yes
151KPNA3KPNA3
Entrez,  Source
karyopherin alpha 3 (importin alpha 4)11673-0.064-0.2960Yes
152RYKRYK
Entrez,  Source
RYK receptor-like tyrosine kinase11696-0.065-0.2905Yes
153PDE8APDE8A
Entrez,  Source
phosphodiesterase 8A11766-0.066-0.2884Yes
154UBL3UBL3
Entrez,  Source
ubiquitin-like 311808-0.068-0.2841Yes
155SLC4A7SLC4A7
Entrez,  Source
solute carrier family 4, sodium bicarbonate cotransporter, member 711826-0.068-0.2778Yes
156SMAD3SMAD3
Entrez,  Source
SMAD, mothers against DPP homolog 3 (Drosophila)11928-0.071-0.2777Yes
157CLASP2CLASP2
Entrez,  Source
cytoplasmic linker associated protein 211968-0.072-0.2727Yes
158PTPRKPTPRK
Entrez,  Source
protein tyrosine phosphatase, receptor type, K11989-0.073-0.2663Yes
159IL1RAPIL1RAP
Entrez,  Source
interleukin 1 receptor accessory protein12123-0.077-0.2679Yes
160PARGPARG
Entrez,  Source
poly (ADP-ribose) glycohydrolase12259-0.081-0.2692Yes
161VEGFCVEGFC
Entrez,  Source
vascular endothelial growth factor C12416-0.088-0.2713Yes
162CASKCASK
Entrez,  Source
calcium/calmodulin-dependent serine protein kinase (MAGUK family)12444-0.088-0.2636Yes
163PRKCIPRKCI
Entrez,  Source
protein kinase C, iota12564-0.095-0.2622Yes
164LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog12577-0.095-0.2526Yes
165TRIOTRIO
Entrez,  Source
triple functional domain (PTPRF interacting)12578-0.095-0.2420Yes
166RB1RB1
Entrez,  Source
retinoblastoma 1 (including osteosarcoma)12607-0.097-0.2334Yes
167STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)12679-0.101-0.2276Yes
168ATP2C1ATP2C1
Entrez,  Source
ATPase, Ca++ transporting, type 2C, member 112741-0.106-0.2205Yes
169MSH2MSH2
Entrez,  Source
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)12758-0.107-0.2099Yes
170PIK3C3PIK3C3
Entrez,  Source
phosphoinositide-3-kinase, class 312766-0.108-0.1985Yes
171PAWRPAWR
Entrez,  Source
PRKC, apoptosis, WT1, regulator12871-0.118-0.1933Yes
172PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 512904-0.122-0.1823Yes
173NMT2NMT2
Entrez,  Source
N-myristoyltransferase 213024-0.135-0.1764Yes
174NRG1NRG1
Entrez,  Source
neuregulin 113047-0.140-0.1627Yes
175RRAS2RRAS2
Entrez,  Source
related RAS viral (r-ras) oncogene homolog 213088-0.147-0.1494Yes
176RUNX1RUNX1
Entrez,  Source
runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)13119-0.153-0.1348Yes
177ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 213146-0.160-0.1191Yes
178TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)13153-0.163-0.1016Yes
179SOS2SOS2
Entrez,  Source
son of sevenless homolog 2 (Drosophila)13162-0.167-0.0838Yes
180CLASP1CLASP1
Entrez,  Source
cytoplasmic linker associated protein 113168-0.170-0.0654Yes
181SCHIP1SCHIP1
Entrez,  Source
schwannomin interacting protein 113195-0.185-0.0469Yes
182PLCE1PLCE1
Entrez,  Source
phospholipase C, epsilon 113205-0.194-0.0262Yes
183F3F3
Entrez,  Source
coagulation factor III (thromboplastin, tissue factor)13312-0.3310.0023Yes
Table: GSEA details [plain text format]



Fig 2: UVC_XPCS_8HR_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: UVC_XPCS_8HR_DN: Random ES distribution   
Gene set null distribution of ES for UVC_XPCS_8HR_DN