Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | V$CREL_01 |
| Enrichment Score (ES) | -0.3613821 |
| Normalized Enrichment Score (NES) | -1.498174 |
| Nominal p-value | 0.0060 |
| FDR q-value | 0.27603123 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAP3K8 | MAP3K8 Entrez, Source | mitogen-activated protein kinase kinase kinase 8 | 9 | 0.350 | 0.0474 | No |
| 2 | CACNG3 | CACNG3 Entrez, Source | calcium channel, voltage-dependent, gamma subunit 3 | 325 | 0.132 | 0.0417 | No |
| 3 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 347 | 0.130 | 0.0580 | No |
| 4 | APBA1 | APBA1 Entrez, Source | amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) | 544 | 0.114 | 0.0588 | No |
| 5 | SLC16A6 | SLC16A6 Entrez, Source | solute carrier family 16, member 6 (monocarboxylic acid transporter 7) | 674 | 0.105 | 0.0636 | No |
| 6 | IER3 | IER3 Entrez, Source | immediate early response 3 | 890 | 0.096 | 0.0605 | No |
| 7 | CD86 | CD86 Entrez, Source | CD86 molecule | 1107 | 0.087 | 0.0561 | No |
| 8 | SLC12A2 | SLC12A2 Entrez, Source | solute carrier family 12 (sodium/potassium/chloride transporters), member 2 | 1114 | 0.087 | 0.0675 | No |
| 9 | UBD | UBD Entrez, Source | ubiquitin D | 1208 | 0.083 | 0.0719 | No |
| 10 | AGC1 | AGC1 Entrez, Source | aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) | 1247 | 0.082 | 0.0803 | No |
| 11 | WNT4 | WNT4 Entrez, Source | wingless-type MMTV integration site family, member 4 | 1250 | 0.082 | 0.0914 | No |
| 12 | CSF1R | CSF1R Entrez, Source | colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog | 1283 | 0.081 | 0.1001 | No |
| 13 | POU2F3 | POU2F3 Entrez, Source | POU domain, class 2, transcription factor 3 | 1357 | 0.079 | 0.1053 | No |
| 14 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 1431 | 0.077 | 0.1104 | No |
| 15 | SOX10 | SOX10 Entrez, Source | SRY (sex determining region Y)-box 10 | 1485 | 0.075 | 0.1166 | No |
| 16 | CASKIN1 | CASKIN1 Entrez, Source | CASK interacting protein 1 | 1599 | 0.072 | 0.1180 | No |
| 17 | STC2 | STC2 Entrez, Source | stanniocalcin 2 | 1937 | 0.064 | 0.1013 | No |
| 18 | SLC30A3 | SLC30A3 Entrez, Source | solute carrier family 30 (zinc transporter), member 3 | 1963 | 0.063 | 0.1082 | No |
| 19 | IFNB1 | IFNB1 Entrez, Source | interferon, beta 1, fibroblast | 1990 | 0.063 | 0.1148 | No |
| 20 | PTGES | PTGES Entrez, Source | prostaglandin E synthase | 2220 | 0.057 | 0.1053 | No |
| 21 | SDC4 | SDC4 Entrez, Source | syndecan 4 (amphiglycan, ryudocan) | 2339 | 0.055 | 0.1039 | No |
| 22 | ADCK4 | ADCK4 Entrez, Source | aarF domain containing kinase 4 | 2411 | 0.054 | 0.1059 | No |
| 23 | GREM1 | GREM1 Entrez, Source | gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) | 2434 | 0.053 | 0.1115 | No |
| 24 | RIMS2 | RIMS2 Entrez, Source | regulating synaptic membrane exocytosis 2 | 2495 | 0.052 | 0.1141 | No |
| 25 | ABI3 | ABI3 Entrez, Source | ABI gene family, member 3 | 2584 | 0.050 | 0.1143 | No |
| 26 | PCSK2 | PCSK2 Entrez, Source | proprotein convertase subtilisin/kexin type 2 | 2588 | 0.050 | 0.1209 | No |
| 27 | COL16A1 | COL16A1 Entrez, Source | collagen, type XVI, alpha 1 | 2723 | 0.048 | 0.1173 | No |
| 28 | GNAO1 | GNAO1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 2843 | 0.045 | 0.1146 | No |
| 29 | EIF4A2 | EIF4A2 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 2 | 2944 | 0.044 | 0.1130 | No |
| 30 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 3390 | 0.037 | 0.0845 | No |
| 31 | ITPKC | ITPKC Entrez, Source | inositol 1,4,5-trisphosphate 3-kinase C | 3435 | 0.036 | 0.0861 | No |
| 32 | FKHL18 | FKHL18 Entrez, Source | forkhead-like 18 (Drosophila) | 3476 | 0.036 | 0.0879 | No |
| 33 | HGF | HGF Entrez, Source | hepatocyte growth factor (hepapoietin A; scatter factor) | 3517 | 0.035 | 0.0897 | No |
| 34 | MSX1 | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 3576 | 0.034 | 0.0900 | No |
| 35 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 3699 | 0.033 | 0.0853 | No |
| 36 | MAPK6 | MAPK6 Entrez, Source | mitogen-activated protein kinase 6 | 3705 | 0.032 | 0.0894 | No |
| 37 | NXPH4 | NXPH4 Entrez, Source | neurexophilin 4 | 3919 | 0.029 | 0.0773 | No |
| 38 | BLR1 | BLR1 Entrez, Source | Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) | 4045 | 0.028 | 0.0717 | No |
| 39 | ARHGAP5 | ARHGAP5 Entrez, Source | Rho GTPase activating protein 5 | 4048 | 0.028 | 0.0753 | No |
| 40 | IL2RA | IL2RA Entrez, Source | interleukin 2 receptor, alpha | 4057 | 0.028 | 0.0785 | No |
| 41 | CD74 | CD74 Entrez, Source | CD74 molecule, major histocompatibility complex, class II invariant chain | 4100 | 0.027 | 0.0790 | No |
| 42 | JAK3 | JAK3 Entrez, Source | Janus kinase 3 (a protein tyrosine kinase, leukocyte) | 4223 | 0.026 | 0.0733 | No |
| 43 | SLC6A12 | SLC6A12 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 | 4308 | 0.025 | 0.0703 | No |
| 44 | TCF8 | TCF8 Entrez, Source | transcription factor 8 (represses interleukin 2 expression) | 4744 | 0.019 | 0.0401 | No |
| 45 | MADCAM1 | MADCAM1 Entrez, Source | mucosal vascular addressin cell adhesion molecule 1 | 5495 | 0.010 | -0.0152 | No |
| 46 | MYST2 | MYST2 Entrez, Source | MYST histone acetyltransferase 2 | 5566 | 0.009 | -0.0192 | No |
| 47 | HCST | HCST Entrez, Source | hematopoietic cell signal transducer | 5756 | 0.007 | -0.0324 | No |
| 48 | FGF12 | FGF12 Entrez, Source | fibroblast growth factor 12 | 5771 | 0.007 | -0.0325 | No |
| 49 | CTDSP1 | CTDSP1 Entrez, Source | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | 5792 | 0.007 | -0.0331 | No |
| 50 | CLCN2 | CLCN2 Entrez, Source | chloride channel 2 | 5847 | 0.006 | -0.0363 | No |
| 51 | CLDN5 | CLDN5 Entrez, Source | claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) | 6273 | 0.002 | -0.0682 | No |
| 52 | RASGRP4 | RASGRP4 Entrez, Source | RAS guanyl releasing protein 4 | 6432 | -0.000 | -0.0802 | No |
| 53 | TCEA2 | TCEA2 Entrez, Source | transcription elongation factor A (SII), 2 | 6779 | -0.004 | -0.1058 | No |
| 54 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 6802 | -0.004 | -0.1070 | No |
| 55 | IER5 | IER5 Entrez, Source | immediate early response 5 | 6813 | -0.004 | -0.1072 | No |
| 56 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 6874 | -0.004 | -0.1111 | No |
| 57 | BLCAP | BLCAP Entrez, Source | bladder cancer associated protein | 7002 | -0.006 | -0.1200 | No |
| 58 | UBE2D3 | UBE2D3 Entrez, Source | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 7172 | -0.007 | -0.1317 | No |
| 59 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 7287 | -0.009 | -0.1392 | No |
| 60 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 7359 | -0.009 | -0.1433 | No |
| 61 | CNKSR1 | CNKSR1 Entrez, Source | connector enhancer of kinase suppressor of Ras 1 | 7479 | -0.010 | -0.1509 | No |
| 62 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 7608 | -0.012 | -0.1589 | No |
| 63 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 7978 | -0.015 | -0.1847 | No |
| 64 | G3BP | G3BP Entrez, Source | - | 8098 | -0.017 | -0.1914 | No |
| 65 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 8110 | -0.017 | -0.1899 | No |
| 66 | IL13 | IL13 Entrez, Source | interleukin 13 | 8256 | -0.018 | -0.1984 | No |
| 67 | PFN1 | PFN1 Entrez, Source | profilin 1 | 8402 | -0.020 | -0.2066 | No |
| 68 | AKT2 | AKT2 Entrez, Source | v-akt murine thymoma viral oncogene homolog 2 | 8477 | -0.020 | -0.2094 | No |
| 69 | GRK5 | GRK5 Entrez, Source | G protein-coupled receptor kinase 5 | 8649 | -0.022 | -0.2193 | No |
| 70 | GATA4 | GATA4 Entrez, Source | GATA binding protein 4 | 8719 | -0.023 | -0.2213 | No |
| 71 | KCNN2 | KCNN2 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 | 8839 | -0.024 | -0.2270 | No |
| 72 | CLOCK | CLOCK Entrez, Source | clock homolog (mouse) | 8909 | -0.025 | -0.2288 | No |
| 73 | DCAMKL1 | DCAMKL1 Entrez, Source | doublecortin and CaM kinase-like 1 | 8938 | -0.025 | -0.2274 | No |
| 74 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 9329 | -0.029 | -0.2528 | No |
| 75 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 9381 | -0.030 | -0.2526 | No |
| 76 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 9571 | -0.032 | -0.2624 | No |
| 77 | YWHAZ | YWHAZ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 9759 | -0.035 | -0.2718 | No |
| 78 | ARHGEF2 | ARHGEF2 Entrez, Source | rho/rac guanine nucleotide exchange factor (GEF) 2 | 9794 | -0.035 | -0.2696 | No |
| 79 | ENO3 | ENO3 Entrez, Source | enolase 3 (beta, muscle) | 9845 | -0.036 | -0.2685 | No |
| 80 | RAB34 | RAB34 Entrez, Source | RAB34, member RAS oncogene family | 9901 | -0.036 | -0.2677 | No |
| 81 | HTR3B | HTR3B Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 3B | 10347 | -0.041 | -0.2957 | No |
| 82 | ZDHHC8 | ZDHHC8 Entrez, Source | zinc finger, DHHC-type containing 8 | 10445 | -0.043 | -0.2972 | No |
| 83 | SMOC1 | SMOC1 Entrez, Source | SPARC related modular calcium binding 1 | 10655 | -0.046 | -0.3067 | No |
| 84 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 10717 | -0.047 | -0.3049 | No |
| 85 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 10811 | -0.048 | -0.3053 | No |
| 86 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 11312 | -0.057 | -0.3353 | No |
| 87 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 11323 | -0.057 | -0.3282 | No |
| 88 | TACC1 | TACC1 Entrez, Source | transforming, acidic coiled-coil containing protein 1 | 11650 | -0.064 | -0.3441 | No |
| 89 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 11713 | -0.065 | -0.3398 | No |
| 90 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 11718 | -0.065 | -0.3312 | No |
| 91 | SMYD2 | SMYD2 Entrez, Source | SET and MYND domain containing 2 | 12033 | -0.074 | -0.3448 | No |
| 92 | DDR1 | DDR1 Entrez, Source | discoidin domain receptor family, member 1 | 12120 | -0.077 | -0.3408 | No |
| 93 | EHD1 | EHD1 Entrez, Source | EH-domain containing 1 | 12179 | -0.079 | -0.3343 | No |
| 94 | GPM6A | GPM6A Entrez, Source | glycoprotein M6A | 12264 | -0.082 | -0.3295 | No |
| 95 | BMP2K | BMP2K Entrez, Source | BMP2 inducible kinase | 12687 | -0.102 | -0.3474 | Yes |
| 96 | CD69 | CD69 Entrez, Source | CD69 molecule | 12743 | -0.106 | -0.3370 | Yes |
| 97 | FLOT1 | FLOT1 Entrez, Source | flotillin 1 | 12744 | -0.106 | -0.3224 | Yes |
| 98 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 12785 | -0.110 | -0.3104 | Yes |
| 99 | NFKB2 | NFKB2 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 12794 | -0.110 | -0.2959 | Yes |
| 100 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 12964 | -0.127 | -0.2912 | Yes |
| 101 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 13071 | -0.143 | -0.2795 | Yes |
| 102 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 13151 | -0.163 | -0.2631 | Yes |
| 103 | FGF1 | FGF1 Entrez, Source | fibroblast growth factor 1 (acidic) | 13172 | -0.171 | -0.2412 | Yes |
| 104 | SMPD3 | SMPD3 Entrez, Source | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) | 13215 | -0.202 | -0.2166 | Yes |
| 105 | LTB | LTB Entrez, Source | lymphotoxin beta (TNF superfamily, member 3) | 13250 | -0.220 | -0.1889 | Yes |
| 106 | EDG5 | EDG5 Entrez, Source | endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 | 13254 | -0.222 | -0.1586 | Yes |
| 107 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13284 | -0.263 | -0.1248 | Yes |
| 108 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13295 | -0.275 | -0.0878 | Yes |
| 109 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 13310 | -0.321 | -0.0448 | Yes |
| 110 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 13315 | -0.343 | 0.0020 | Yes |
