Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | V$E2F1_Q3 |
| Enrichment Score (ES) | -0.4038241 |
| Normalized Enrichment Score (NES) | -1.6231897 |
| Nominal p-value | 0.0040650405 |
| FDR q-value | 0.21449777 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 1024 | 0.091 | -0.0599 | No |
| 2 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 1027 | 0.091 | -0.0428 | No |
| 3 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 1165 | 0.085 | -0.0369 | No |
| 4 | SLCO3A1 | SLCO3A1 Entrez, Source | solute carrier organic anion transporter family, member 3A1 | 1303 | 0.080 | -0.0319 | No |
| 5 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 1387 | 0.078 | -0.0232 | No |
| 6 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 1406 | 0.077 | -0.0098 | No |
| 7 | TRIM39 | TRIM39 Entrez, Source | tripartite motif-containing 39 | 1588 | 0.073 | -0.0095 | No |
| 8 | DCK | DCK Entrez, Source | deoxycytidine kinase | 1598 | 0.072 | 0.0036 | No |
| 9 | BARHL1 | BARHL1 Entrez, Source | BarH-like 1 (Drosophila) | 1630 | 0.072 | 0.0150 | No |
| 10 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 1799 | 0.067 | 0.0152 | No |
| 11 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 2033 | 0.062 | 0.0094 | No |
| 12 | SYT11 | SYT11 Entrez, Source | synaptotagmin XI | 2075 | 0.061 | 0.0179 | No |
| 13 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 2111 | 0.060 | 0.0267 | No |
| 14 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 2376 | 0.054 | 0.0171 | No |
| 15 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 2400 | 0.054 | 0.0257 | No |
| 16 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 2916 | 0.044 | -0.0047 | No |
| 17 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 3360 | 0.037 | -0.0310 | No |
| 18 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 3390 | 0.037 | -0.0261 | No |
| 19 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 3481 | 0.035 | -0.0261 | No |
| 20 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 3594 | 0.034 | -0.0281 | No |
| 21 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 3670 | 0.033 | -0.0275 | No |
| 22 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 3853 | 0.030 | -0.0354 | No |
| 23 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 3892 | 0.030 | -0.0326 | No |
| 24 | CACNA1G | CACNA1G Entrez, Source | calcium channel, voltage-dependent, alpha 1G subunit | 3937 | 0.029 | -0.0303 | No |
| 25 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 4006 | 0.028 | -0.0301 | No |
| 26 | ATP1B4 | ATP1B4 Entrez, Source | ATPase, (Na+)/K+ transporting, beta 4 polypeptide | 4029 | 0.028 | -0.0264 | No |
| 27 | NCL | NCL Entrez, Source | nucleolin | 4105 | 0.027 | -0.0269 | No |
| 28 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 4134 | 0.027 | -0.0239 | No |
| 29 | PELP1 | PELP1 Entrez, Source | proline, glutamic acid and leucine rich protein 1 | 4140 | 0.026 | -0.0192 | No |
| 30 | SYT6 | SYT6 Entrez, Source | synaptotagmin VI | 4551 | 0.021 | -0.0461 | No |
| 31 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 4862 | 0.018 | -0.0661 | No |
| 32 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 5064 | 0.015 | -0.0784 | No |
| 33 | CORT | CORT Entrez, Source | cortistatin | 5114 | 0.015 | -0.0792 | No |
| 34 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 5517 | 0.010 | -0.1076 | No |
| 35 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 5696 | 0.008 | -0.1196 | No |
| 36 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 5816 | 0.007 | -0.1273 | No |
| 37 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 6161 | 0.003 | -0.1527 | No |
| 38 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 6246 | 0.002 | -0.1587 | No |
| 39 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 6384 | 0.000 | -0.1689 | No |
| 40 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 6747 | -0.003 | -0.1956 | No |
| 41 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 7235 | -0.008 | -0.2308 | No |
| 42 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 7323 | -0.009 | -0.2357 | No |
| 43 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 7327 | -0.009 | -0.2343 | No |
| 44 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 7331 | -0.009 | -0.2328 | No |
| 45 | ABCE1 | ABCE1 Entrez, Source | ATP-binding cassette, sub-family E (OABP), member 1 | 7480 | -0.010 | -0.2420 | No |
| 46 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 7506 | -0.010 | -0.2418 | No |
| 47 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 7529 | -0.011 | -0.2414 | No |
| 48 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 7552 | -0.011 | -0.2410 | No |
| 49 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 7697 | -0.012 | -0.2495 | No |
| 50 | TCP1 | TCP1 Entrez, Source | t-complex 1 | 7728 | -0.013 | -0.2493 | No |
| 51 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 7821 | -0.014 | -0.2536 | No |
| 52 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 7999 | -0.016 | -0.2640 | No |
| 53 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 8055 | -0.016 | -0.2650 | No |
| 54 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 8057 | -0.016 | -0.2620 | No |
| 55 | GRIK2 | GRIK2 Entrez, Source | glutamate receptor, ionotropic, kainate 2 | 8233 | -0.018 | -0.2717 | No |
| 56 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 8303 | -0.019 | -0.2733 | No |
| 57 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 8745 | -0.023 | -0.3022 | No |
| 58 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 9003 | -0.026 | -0.3166 | No |
| 59 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 9098 | -0.027 | -0.3185 | No |
| 60 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 9143 | -0.027 | -0.3166 | No |
| 61 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 9331 | -0.029 | -0.3251 | No |
| 62 | BAT3 | BAT3 Entrez, Source | HLA-B associated transcript 3 | 9498 | -0.031 | -0.3317 | No |
| 63 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 9894 | -0.036 | -0.3546 | No |
| 64 | SLC25A3 | SLC25A3 Entrez, Source | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 9966 | -0.037 | -0.3529 | No |
| 65 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 10006 | -0.037 | -0.3487 | No |
| 66 | ADCY8 | ADCY8 Entrez, Source | adenylate cyclase 8 (brain) | 10199 | -0.039 | -0.3557 | No |
| 67 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 10597 | -0.045 | -0.3771 | No |
| 68 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 10628 | -0.045 | -0.3707 | No |
| 69 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 10631 | -0.045 | -0.3622 | No |
| 70 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 10796 | -0.048 | -0.3654 | No |
| 71 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 10811 | -0.048 | -0.3573 | No |
| 72 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 10896 | -0.050 | -0.3541 | No |
| 73 | SHMT1 | SHMT1 Entrez, Source | serine hydroxymethyltransferase 1 (soluble) | 11060 | -0.052 | -0.3565 | No |
| 74 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 11296 | -0.057 | -0.3634 | No |
| 75 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11355 | -0.058 | -0.3567 | No |
| 76 | XTP3TPA | XTP3TPA Entrez, Source | - | 11867 | -0.069 | -0.3820 | No |
| 77 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 11994 | -0.073 | -0.3776 | No |
| 78 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 12342 | -0.085 | -0.3876 | Yes |
| 79 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 12529 | -0.093 | -0.3838 | Yes |
| 80 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 12555 | -0.094 | -0.3677 | Yes |
| 81 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 12603 | -0.097 | -0.3527 | Yes |
| 82 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 12692 | -0.103 | -0.3397 | Yes |
| 83 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 12758 | -0.107 | -0.3241 | Yes |
| 84 | TMPO | TMPO Entrez, Source | thymopoietin | 12812 | -0.111 | -0.3068 | Yes |
| 85 | SSBP3 | SSBP3 Entrez, Source | single stranded DNA binding protein 3 | 13085 | -0.147 | -0.2993 | Yes |
| 86 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13174 | -0.172 | -0.2731 | Yes |
| 87 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 13185 | -0.179 | -0.2396 | Yes |
| 88 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13196 | -0.186 | -0.2048 | Yes |
| 89 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13232 | -0.213 | -0.1667 | Yes |
| 90 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13314 | -0.341 | -0.1076 | Yes |
| 91 | ASCL1 | ASCL1 Entrez, Source | achaete-scute complex-like 1 (Drosophila) | 13337 | -0.574 | 0.0004 | Yes |
