Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | V$E2F_Q3 |
| Enrichment Score (ES) | -0.41870946 |
| Normalized Enrichment Score (NES) | -1.6534512 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.19352645 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 569 | 0.112 | -0.0198 | No |
| 2 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 1027 | 0.091 | -0.0356 | No |
| 3 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 1165 | 0.085 | -0.0284 | No |
| 4 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 1387 | 0.078 | -0.0290 | No |
| 5 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 1420 | 0.077 | -0.0155 | No |
| 6 | DCK | DCK Entrez, Source | deoxycytidine kinase | 1598 | 0.072 | -0.0139 | No |
| 7 | BARHL1 | BARHL1 Entrez, Source | BarH-like 1 (Drosophila) | 1630 | 0.072 | -0.0015 | No |
| 8 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 1799 | 0.067 | -0.0002 | No |
| 9 | SYT11 | SYT11 Entrez, Source | synaptotagmin XI | 2075 | 0.061 | -0.0085 | No |
| 10 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 2376 | 0.054 | -0.0200 | No |
| 11 | HTF9C | HTF9C Entrez, Source | - | 2553 | 0.051 | -0.0228 | No |
| 12 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 2916 | 0.044 | -0.0410 | No |
| 13 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 3143 | 0.041 | -0.0495 | No |
| 14 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 3225 | 0.040 | -0.0475 | No |
| 15 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 3343 | 0.038 | -0.0486 | No |
| 16 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 3360 | 0.037 | -0.0421 | No |
| 17 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 3481 | 0.035 | -0.0438 | No |
| 18 | LHX5 | LHX5 Entrez, Source | LIM homeobox 5 | 3564 | 0.034 | -0.0429 | No |
| 19 | SEZ6 | SEZ6 Entrez, Source | seizure related 6 homolog (mouse) | 3603 | 0.034 | -0.0388 | No |
| 20 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 3853 | 0.030 | -0.0513 | No |
| 21 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 3869 | 0.030 | -0.0463 | No |
| 22 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3887 | 0.030 | -0.0414 | No |
| 23 | CACNA1G | CACNA1G Entrez, Source | calcium channel, voltage-dependent, alpha 1G subunit | 3937 | 0.029 | -0.0391 | No |
| 24 | NCL | NCL Entrez, Source | nucleolin | 4105 | 0.027 | -0.0461 | No |
| 25 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 4134 | 0.027 | -0.0428 | No |
| 26 | PELP1 | PELP1 Entrez, Source | proline, glutamic acid and leucine rich protein 1 | 4140 | 0.026 | -0.0377 | No |
| 27 | RHD | RHD Entrez, Source | Rh blood group, D antigen | 4277 | 0.025 | -0.0428 | No |
| 28 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 4862 | 0.018 | -0.0832 | No |
| 29 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 5517 | 0.010 | -0.1304 | No |
| 30 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 5696 | 0.008 | -0.1422 | No |
| 31 | CTDSP1 | CTDSP1 Entrez, Source | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | 5792 | 0.007 | -0.1480 | No |
| 32 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 5816 | 0.007 | -0.1484 | No |
| 33 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 5943 | 0.005 | -0.1568 | No |
| 34 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 6141 | 0.003 | -0.1710 | No |
| 35 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 6161 | 0.003 | -0.1719 | No |
| 36 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 6595 | -0.002 | -0.2041 | No |
| 37 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 6719 | -0.003 | -0.2128 | No |
| 38 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 7101 | -0.007 | -0.2402 | No |
| 39 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 7107 | -0.007 | -0.2392 | No |
| 40 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 7288 | -0.009 | -0.2510 | No |
| 41 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 7327 | -0.009 | -0.2520 | No |
| 42 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 7331 | -0.009 | -0.2504 | No |
| 43 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 7506 | -0.010 | -0.2614 | No |
| 44 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 7552 | -0.011 | -0.2625 | No |
| 45 | CLTA | CLTA Entrez, Source | clathrin, light chain (Lca) | 7649 | -0.012 | -0.2673 | No |
| 46 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 7684 | -0.012 | -0.2673 | No |
| 47 | TCP1 | TCP1 Entrez, Source | t-complex 1 | 7728 | -0.013 | -0.2679 | No |
| 48 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 7768 | -0.013 | -0.2681 | No |
| 49 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 7999 | -0.016 | -0.2822 | No |
| 50 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 8055 | -0.016 | -0.2830 | No |
| 51 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 8057 | -0.016 | -0.2797 | No |
| 52 | GRIK2 | GRIK2 Entrez, Source | glutamate receptor, ionotropic, kainate 2 | 8233 | -0.018 | -0.2892 | No |
| 53 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 8252 | -0.018 | -0.2868 | No |
| 54 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 8303 | -0.019 | -0.2867 | No |
| 55 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 8707 | -0.023 | -0.3124 | No |
| 56 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 9003 | -0.026 | -0.3293 | No |
| 57 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 9098 | -0.027 | -0.3308 | No |
| 58 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 9143 | -0.027 | -0.3285 | No |
| 59 | BAT3 | BAT3 Entrez, Source | HLA-B associated transcript 3 | 9498 | -0.031 | -0.3487 | No |
| 60 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 9749 | -0.034 | -0.3605 | No |
| 61 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 9894 | -0.036 | -0.3639 | No |
| 62 | SLC25A3 | SLC25A3 Entrez, Source | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 9966 | -0.037 | -0.3617 | No |
| 63 | ADCY8 | ADCY8 Entrez, Source | adenylate cyclase 8 (brain) | 10199 | -0.039 | -0.3710 | No |
| 64 | PPP1CC | PPP1CC Entrez, Source | protein phosphatase 1, catalytic subunit, gamma isoform | 10356 | -0.041 | -0.3743 | No |
| 65 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 10533 | -0.044 | -0.3785 | No |
| 66 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 10597 | -0.045 | -0.3740 | No |
| 67 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 10631 | -0.045 | -0.3672 | No |
| 68 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 10796 | -0.048 | -0.3697 | No |
| 69 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 10848 | -0.049 | -0.3635 | No |
| 70 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 10896 | -0.050 | -0.3568 | No |
| 71 | SHMT1 | SHMT1 Entrez, Source | serine hydroxymethyltransferase 1 (soluble) | 11060 | -0.052 | -0.3584 | No |
| 72 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11355 | -0.058 | -0.3686 | No |
| 73 | XTP3TPA | XTP3TPA Entrez, Source | - | 11867 | -0.069 | -0.3930 | No |
| 74 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 11925 | -0.070 | -0.3827 | No |
| 75 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 11994 | -0.073 | -0.3728 | No |
| 76 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 12603 | -0.097 | -0.3987 | Yes |
| 77 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 12685 | -0.102 | -0.3838 | Yes |
| 78 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12787 | -0.110 | -0.3688 | Yes |
| 79 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 12854 | -0.115 | -0.3500 | Yes |
| 80 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 12948 | -0.126 | -0.3310 | Yes |
| 81 | SSBP3 | SSBP3 Entrez, Source | single stranded DNA binding protein 3 | 13085 | -0.147 | -0.3110 | Yes |
| 82 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 13133 | -0.158 | -0.2821 | Yes |
| 83 | ONECUT1 | ONECUT1 Entrez, Source | one cut domain, family member 1 | 13171 | -0.170 | -0.2497 | Yes |
| 84 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13174 | -0.172 | -0.2144 | Yes |
| 85 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13196 | -0.186 | -0.1776 | Yes |
| 86 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13314 | -0.341 | -0.1162 | Yes |
| 87 | ASCL1 | ASCL1 Entrez, Source | achaete-scute complex-like 1 (Drosophila) | 13337 | -0.574 | 0.0004 | Yes |
