Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | V$FXR_IR1_Q6 |
| Enrichment Score (ES) | -0.4039931 |
| Normalized Enrichment Score (NES) | -1.4672699 |
| Nominal p-value | 0.044660196 |
| FDR q-value | 0.29957062 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NR0B2 | NR0B2 Entrez, Source | nuclear receptor subfamily 0, group B, member 2 | 38 | 0.227 | 0.0692 | No |
| 2 | SCNN1A | SCNN1A Entrez, Source | sodium channel, nonvoltage-gated 1 alpha | 433 | 0.123 | 0.0785 | No |
| 3 | HSPB2 | HSPB2 Entrez, Source | heat shock 27kDa protein 2 | 1028 | 0.091 | 0.0625 | No |
| 4 | VAMP2 | VAMP2 Entrez, Source | vesicle-associated membrane protein 2 (synaptobrevin 2) | 1269 | 0.081 | 0.0702 | No |
| 5 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 1845 | 0.066 | 0.0479 | No |
| 6 | FGF6 | FGF6 Entrez, Source | fibroblast growth factor 6 | 1981 | 0.063 | 0.0578 | No |
| 7 | SLC13A5 | SLC13A5 Entrez, Source | solute carrier family 13 (sodium-dependent citrate transporter), member 5 | 2025 | 0.062 | 0.0741 | No |
| 8 | GRIK3 | GRIK3 Entrez, Source | glutamate receptor, ionotropic, kainate 3 | 2525 | 0.051 | 0.0528 | No |
| 9 | FABP6 | FABP6 Entrez, Source | fatty acid binding protein 6, ileal (gastrotropin) | 2755 | 0.047 | 0.0505 | No |
| 10 | CENTG1 | CENTG1 Entrez, Source | centaurin, gamma 1 | 3066 | 0.042 | 0.0405 | No |
| 11 | VAMP1 | VAMP1 Entrez, Source | vesicle-associated membrane protein 1 (synaptobrevin 1) | 3154 | 0.041 | 0.0469 | No |
| 12 | GPR12 | GPR12 Entrez, Source | G protein-coupled receptor 12 | 3795 | 0.031 | 0.0086 | No |
| 13 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 4407 | 0.023 | -0.0300 | No |
| 14 | EIF5 | EIF5 Entrez, Source | eukaryotic translation initiation factor 5 | 4823 | 0.018 | -0.0555 | No |
| 15 | GDNF | GDNF Entrez, Source | glial cell derived neurotrophic factor | 4828 | 0.018 | -0.0500 | No |
| 16 | NDRG2 | NDRG2 Entrez, Source | NDRG family member 2 | 5272 | 0.013 | -0.0793 | No |
| 17 | DAB2 | DAB2 Entrez, Source | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 5442 | 0.011 | -0.0885 | No |
| 18 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 5766 | 0.007 | -0.1106 | No |
| 19 | RARA | RARA Entrez, Source | retinoic acid receptor, alpha | 5779 | 0.007 | -0.1092 | No |
| 20 | KCNIP2 | KCNIP2 Entrez, Source | Kv channel interacting protein 2 | 5898 | 0.006 | -0.1164 | No |
| 21 | EEF1A1 | EEF1A1 Entrez, Source | eukaryotic translation elongation factor 1 alpha 1 | 6030 | 0.004 | -0.1249 | No |
| 22 | ABCB11 | ABCB11 Entrez, Source | ATP-binding cassette, sub-family B (MDR/TAP), member 11 | 6147 | 0.003 | -0.1326 | No |
| 23 | KITLG | KITLG Entrez, Source | KIT ligand | 6293 | 0.001 | -0.1431 | No |
| 24 | RNASE4 | RNASE4 Entrez, Source | ribonuclease, RNase A family, 4 | 6380 | 0.000 | -0.1494 | No |
| 25 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6594 | -0.002 | -0.1649 | No |
| 26 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 6724 | -0.003 | -0.1736 | No |
| 27 | TTL | TTL Entrez, Source | tubulin tyrosine ligase | 6964 | -0.005 | -0.1899 | No |
| 28 | MRPS18B | MRPS18B Entrez, Source | mitochondrial ribosomal protein S18B | 7041 | -0.006 | -0.1937 | No |
| 29 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 7463 | -0.010 | -0.2222 | No |
| 30 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 9098 | -0.027 | -0.3366 | No |
| 31 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 9124 | -0.027 | -0.3298 | No |
| 32 | PDC | PDC Entrez, Source | phosducin | 9436 | -0.031 | -0.3435 | No |
| 33 | RNF14 | RNF14 Entrez, Source | ring finger protein 14 | 9724 | -0.034 | -0.3543 | No |
| 34 | ADCY8 | ADCY8 Entrez, Source | adenylate cyclase 8 (brain) | 10199 | -0.039 | -0.3774 | No |
| 35 | KLHL13 | KLHL13 Entrez, Source | kelch-like 13 (Drosophila) | 10205 | -0.040 | -0.3653 | No |
| 36 | FOXA1 | FOXA1 Entrez, Source | forkhead box A1 | 10364 | -0.041 | -0.3640 | No |
| 37 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 10896 | -0.050 | -0.3883 | Yes |
| 38 | TTC12 | TTC12 Entrez, Source | tetratricopeptide repeat domain 12 | 10908 | -0.050 | -0.3734 | Yes |
| 39 | PPP2R2B | PPP2R2B Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform | 10989 | -0.051 | -0.3633 | Yes |
| 40 | DLGAP4 | DLGAP4 Entrez, Source | discs, large (Drosophila) homolog-associated protein 4 | 11287 | -0.057 | -0.3677 | Yes |
| 41 | ARF3 | ARF3 Entrez, Source | ADP-ribosylation factor 3 | 11302 | -0.057 | -0.3507 | Yes |
| 42 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 11928 | -0.071 | -0.3753 | Yes |
| 43 | ST7 | ST7 Entrez, Source | suppression of tumorigenicity 7 | 11936 | -0.071 | -0.3534 | Yes |
| 44 | LIMK2 | LIMK2 Entrez, Source | LIM domain kinase 2 | 11957 | -0.071 | -0.3323 | Yes |
| 45 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 12014 | -0.073 | -0.3133 | Yes |
| 46 | SCAMP5 | SCAMP5 Entrez, Source | secretory carrier membrane protein 5 | 12035 | -0.074 | -0.2914 | Yes |
| 47 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 12899 | -0.121 | -0.3179 | Yes |
| 48 | RAB3C | RAB3C Entrez, Source | RAB3C, member RAS oncogene family | 12925 | -0.124 | -0.2806 | Yes |
| 49 | SSBP3 | SSBP3 Entrez, Source | single stranded DNA binding protein 3 | 13085 | -0.147 | -0.2462 | Yes |
| 50 | CLDN7 | CLDN7 Entrez, Source | claudin 7 | 13101 | -0.150 | -0.1998 | Yes |
| 51 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13314 | -0.341 | -0.1078 | Yes |
| 52 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 13317 | -0.347 | 0.0019 | Yes |
