Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | V$FXR_Q3 |
| Enrichment Score (ES) | 0.4884455 |
| Normalized Enrichment Score (NES) | 1.7234404 |
| Nominal p-value | 0.011904762 |
| FDR q-value | 0.11953797 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 10 | 0.347 | 0.1089 | Yes |
| 2 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 14 | 0.295 | 0.2022 | Yes |
| 3 | NR0B2 | NR0B2 Entrez, Source | nuclear receptor subfamily 0, group B, member 2 | 38 | 0.227 | 0.2724 | Yes |
| 4 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 41 | 0.224 | 0.3432 | Yes |
| 5 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 234 | 0.143 | 0.3742 | Yes |
| 6 | NTRK3 | NTRK3 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 3 | 474 | 0.120 | 0.3941 | Yes |
| 7 | SV2A | SV2A Entrez, Source | synaptic vesicle glycoprotein 2A | 621 | 0.109 | 0.4176 | Yes |
| 8 | HSPB2 | HSPB2 Entrez, Source | heat shock 27kDa protein 2 | 1028 | 0.091 | 0.4157 | Yes |
| 9 | KIF5A | KIF5A Entrez, Source | kinesin family member 5A | 1145 | 0.086 | 0.4341 | Yes |
| 10 | VAMP2 | VAMP2 Entrez, Source | vesicle-associated membrane protein 2 (synaptobrevin 2) | 1269 | 0.081 | 0.4506 | Yes |
| 11 | HAS2 | HAS2 Entrez, Source | hyaluronan synthase 2 | 1343 | 0.079 | 0.4701 | Yes |
| 12 | IBSP | IBSP Entrez, Source | integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II) | 1424 | 0.077 | 0.4884 | Yes |
| 13 | STC2 | STC2 Entrez, Source | stanniocalcin 2 | 1937 | 0.064 | 0.4701 | No |
| 14 | FGF14 | FGF14 Entrez, Source | fibroblast growth factor 14 | 2352 | 0.055 | 0.4563 | No |
| 15 | LHX1 | LHX1 Entrez, Source | LIM homeobox 1 | 2395 | 0.054 | 0.4702 | No |
| 16 | GRIK3 | GRIK3 Entrez, Source | glutamate receptor, ionotropic, kainate 3 | 2525 | 0.051 | 0.4767 | No |
| 17 | FABP6 | FABP6 Entrez, Source | fatty acid binding protein 6, ileal (gastrotropin) | 2755 | 0.047 | 0.4743 | No |
| 18 | PDE1A | PDE1A Entrez, Source | phosphodiesterase 1A, calmodulin-dependent | 2839 | 0.045 | 0.4825 | No |
| 19 | MOS | MOS Entrez, Source | v-mos Moloney murine sarcoma viral oncogene homolog | 3243 | 0.039 | 0.4647 | No |
| 20 | OTX2 | OTX2 Entrez, Source | orthodenticle homolog 2 (Drosophila) | 3447 | 0.036 | 0.4608 | No |
| 21 | LMO3 | LMO3 Entrez, Source | LIM domain only 3 (rhombotin-like 2) | 3623 | 0.033 | 0.4582 | No |
| 22 | OTP | OTP Entrez, Source | orthopedia homolog (Drosophila) | 3948 | 0.029 | 0.4431 | No |
| 23 | ABCG4 | ABCG4 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 4 | 4060 | 0.028 | 0.4434 | No |
| 24 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 4407 | 0.023 | 0.4248 | No |
| 25 | WDR20 | WDR20 Entrez, Source | WD repeat domain 20 | 4436 | 0.023 | 0.4299 | No |
| 26 | TRIB1 | TRIB1 Entrez, Source | tribbles homolog 1 (Drosophila) | 5150 | 0.014 | 0.3808 | No |
| 27 | ITIH3 | ITIH3 Entrez, Source | inter-alpha (globulin) inhibitor H3 | 5392 | 0.011 | 0.3663 | No |
| 28 | GUCY2F | GUCY2F Entrez, Source | guanylate cyclase 2F, retinal | 5409 | 0.011 | 0.3686 | No |
| 29 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 5766 | 0.007 | 0.3441 | No |
| 30 | EFEMP2 | EFEMP2 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 2 | 6367 | 0.001 | 0.2992 | No |
| 31 | BAMBI | BAMBI Entrez, Source | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) | 7218 | -0.008 | 0.2378 | No |
| 32 | FBXO9 | FBXO9 Entrez, Source | F-box protein 9 | 8093 | -0.017 | 0.1773 | No |
| 33 | ZIC1 | ZIC1 Entrez, Source | Zic family member 1 (odd-paired homolog, Drosophila) | 8326 | -0.019 | 0.1659 | No |
| 34 | ATP5C1 | ATP5C1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 | 8795 | -0.024 | 0.1382 | No |
| 35 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 9604 | -0.033 | 0.0878 | No |
| 36 | STOML2 | STOML2 Entrez, Source | stomatin (EPB72)-like 2 | 10058 | -0.038 | 0.0658 | No |
| 37 | ITPR1 | ITPR1 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 1 | 10751 | -0.047 | 0.0286 | No |
| 38 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 10896 | -0.050 | 0.0335 | No |
| 39 | FUT8 | FUT8 Entrez, Source | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 11656 | -0.064 | -0.0033 | No |
| 40 | UBL3 | UBL3 Entrez, Source | ubiquitin-like 3 | 11808 | -0.068 | 0.0067 | No |
| 41 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 12014 | -0.073 | 0.0145 | No |
| 42 | IL2RG | IL2RG Entrez, Source | interleukin 2 receptor, gamma (severe combined immunodeficiency) | 12775 | -0.109 | -0.0082 | No |
| 43 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 13148 | -0.161 | 0.0146 | No |
