Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | V$NFKAPPAB_01 |
| Enrichment Score (ES) | -0.44183528 |
| Normalized Enrichment Score (NES) | -1.8661126 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.10109507 |
| FWER p-Value | 0.859 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAP3K8 | MAP3K8 Entrez, Source | mitogen-activated protein kinase kinase kinase 8 | 9 | 0.350 | 0.0425 | No |
| 2 | IL23A | IL23A Entrez, Source | interleukin 23, alpha subunit p19 | 175 | 0.153 | 0.0490 | No |
| 3 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 347 | 0.130 | 0.0521 | No |
| 4 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 392 | 0.126 | 0.0643 | No |
| 5 | CLCN1 | CLCN1 Entrez, Source | chloride channel 1, skeletal muscle (Thomsen disease, autosomal dominant) | 715 | 0.103 | 0.0527 | No |
| 6 | BFSP1 | BFSP1 Entrez, Source | beaded filament structural protein 1, filensin | 843 | 0.098 | 0.0551 | No |
| 7 | KCNN3 | KCNN3 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 | 1040 | 0.090 | 0.0514 | No |
| 8 | SLC12A2 | SLC12A2 Entrez, Source | solute carrier family 12 (sodium/potassium/chloride transporters), member 2 | 1114 | 0.087 | 0.0566 | No |
| 9 | UBD | UBD Entrez, Source | ubiquitin D | 1208 | 0.083 | 0.0598 | No |
| 10 | AGC1 | AGC1 Entrez, Source | aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) | 1247 | 0.082 | 0.0670 | No |
| 11 | GRIN2D | GRIN2D Entrez, Source | glutamate receptor, ionotropic, N-methyl D-aspartate 2D | 1375 | 0.078 | 0.0671 | No |
| 12 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 1431 | 0.077 | 0.0724 | No |
| 13 | SOX10 | SOX10 Entrez, Source | SRY (sex determining region Y)-box 10 | 1485 | 0.075 | 0.0776 | No |
| 14 | EDN2 | EDN2 Entrez, Source | endothelin 2 | 1719 | 0.069 | 0.0686 | No |
| 15 | STC2 | STC2 Entrez, Source | stanniocalcin 2 | 1937 | 0.064 | 0.0600 | No |
| 16 | OPCML | OPCML Entrez, Source | opioid binding protein/cell adhesion molecule-like | 1988 | 0.063 | 0.0640 | No |
| 17 | IFNB1 | IFNB1 Entrez, Source | interferon, beta 1, fibroblast | 1990 | 0.063 | 0.0717 | No |
| 18 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 2302 | 0.055 | 0.0550 | No |
| 19 | SDC4 | SDC4 Entrez, Source | syndecan 4 (amphiglycan, ryudocan) | 2339 | 0.055 | 0.0590 | No |
| 20 | RALGDS | RALGDS Entrez, Source | ral guanine nucleotide dissociation stimulator | 2347 | 0.055 | 0.0652 | No |
| 21 | GREM1 | GREM1 Entrez, Source | gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) | 2434 | 0.053 | 0.0653 | No |
| 22 | ZBTB9 | ZBTB9 Entrez, Source | zinc finger and BTB domain containing 9 | 2486 | 0.052 | 0.0678 | No |
| 23 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 2487 | 0.052 | 0.0742 | No |
| 24 | RIMS2 | RIMS2 Entrez, Source | regulating synaptic membrane exocytosis 2 | 2495 | 0.052 | 0.0800 | No |
| 25 | MAG | MAG Entrez, Source | myelin associated glycoprotein | 2504 | 0.051 | 0.0857 | No |
| 26 | KCNH3 | KCNH3 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 3 | 2561 | 0.050 | 0.0877 | No |
| 27 | PCSK2 | PCSK2 Entrez, Source | proprotein convertase subtilisin/kexin type 2 | 2588 | 0.050 | 0.0919 | No |
| 28 | COL16A1 | COL16A1 Entrez, Source | collagen, type XVI, alpha 1 | 2723 | 0.048 | 0.0876 | No |
| 29 | GNAO1 | GNAO1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 2843 | 0.045 | 0.0843 | No |
| 30 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 3039 | 0.042 | 0.0747 | No |
| 31 | UBE2I | UBE2I Entrez, Source | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 3272 | 0.039 | 0.0620 | No |
| 32 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 3390 | 0.037 | 0.0577 | No |
| 33 | IL1RN | IL1RN Entrez, Source | interleukin 1 receptor antagonist | 3400 | 0.037 | 0.0615 | No |
| 34 | FKHL18 | FKHL18 Entrez, Source | forkhead-like 18 (Drosophila) | 3476 | 0.036 | 0.0603 | No |
| 35 | SEC14L2 | SEC14L2 Entrez, Source | SEC14-like 2 (S. cerevisiae) | 3545 | 0.035 | 0.0594 | No |
| 36 | SHOX2 | SHOX2 Entrez, Source | short stature homeobox 2 | 3550 | 0.035 | 0.0633 | No |
| 37 | LTA | LTA Entrez, Source | lymphotoxin alpha (TNF superfamily, member 1) | 3561 | 0.034 | 0.0668 | No |
| 38 | MSX1 | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 3576 | 0.034 | 0.0700 | No |
| 39 | ASCL3 | ASCL3 Entrez, Source | achaete-scute complex (Drosophila) homolog-like 3 | 3829 | 0.031 | 0.0547 | No |
| 40 | BMF | BMF Entrez, Source | Bcl2 modifying factor | 4020 | 0.028 | 0.0438 | No |
| 41 | GABRB1 | GABRB1 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 1 | 4033 | 0.028 | 0.0464 | No |
| 42 | BLR1 | BLR1 Entrez, Source | Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) | 4045 | 0.028 | 0.0489 | No |
| 43 | ARHGAP5 | ARHGAP5 Entrez, Source | Rho GTPase activating protein 5 | 4048 | 0.028 | 0.0522 | No |
| 44 | IL2RA | IL2RA Entrez, Source | interleukin 2 receptor, alpha | 4057 | 0.028 | 0.0550 | No |
| 45 | NTN1 | NTN1 Entrez, Source | netrin 1 | 4193 | 0.026 | 0.0480 | No |
| 46 | JAK3 | JAK3 Entrez, Source | Janus kinase 3 (a protein tyrosine kinase, leukocyte) | 4223 | 0.026 | 0.0490 | No |
| 47 | FBXL12 | FBXL12 Entrez, Source | F-box and leucine-rich repeat protein 12 | 4261 | 0.025 | 0.0493 | No |
| 48 | SLC6A12 | SLC6A12 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 | 4308 | 0.025 | 0.0488 | No |
| 49 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 4868 | 0.018 | 0.0087 | No |
| 50 | KCNS3 | KCNS3 Entrez, Source | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 | 5174 | 0.014 | -0.0126 | No |
| 51 | ZFP36L2 | ZFP36L2 Entrez, Source | zinc finger protein 36, C3H type-like 2 | 5350 | 0.012 | -0.0243 | No |
| 52 | BCKDK | BCKDK Entrez, Source | branched chain ketoacid dehydrogenase kinase | 5381 | 0.011 | -0.0252 | No |
| 53 | PLAU | PLAU Entrez, Source | plasminogen activator, urokinase | 5422 | 0.011 | -0.0269 | No |
| 54 | MADCAM1 | MADCAM1 Entrez, Source | mucosal vascular addressin cell adhesion molecule 1 | 5495 | 0.010 | -0.0310 | No |
| 55 | SLC11A2 | SLC11A2 Entrez, Source | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 5523 | 0.010 | -0.0318 | No |
| 56 | FGF17 | FGF17 Entrez, Source | fibroblast growth factor 17 | 5630 | 0.009 | -0.0388 | No |
| 57 | HCST | HCST Entrez, Source | hematopoietic cell signal transducer | 5756 | 0.007 | -0.0473 | No |
| 58 | GPHN | GPHN Entrez, Source | gephyrin | 5880 | 0.006 | -0.0559 | No |
| 59 | ZNF403 | ZNF403 Entrez, Source | zinc finger protein 403 | 6084 | 0.004 | -0.0708 | No |
| 60 | SAMSN1 | SAMSN1 Entrez, Source | SAM domain, SH3 domain and nuclear localisation signals, 1 | 6106 | 0.004 | -0.0719 | No |
| 61 | TCEA2 | TCEA2 Entrez, Source | transcription elongation factor A (SII), 2 | 6779 | -0.004 | -0.1223 | No |
| 62 | IER5 | IER5 Entrez, Source | immediate early response 5 | 6813 | -0.004 | -0.1243 | No |
| 63 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 6874 | -0.004 | -0.1283 | No |
| 64 | UBE2D3 | UBE2D3 Entrez, Source | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 7172 | -0.007 | -0.1498 | No |
| 65 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 7287 | -0.009 | -0.1574 | No |
| 66 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 7868 | -0.014 | -0.1995 | No |
| 67 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 7978 | -0.015 | -0.2058 | No |
| 68 | AGPAT1 | AGPAT1 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) | 7994 | -0.016 | -0.2050 | No |
| 69 | G3BP | G3BP Entrez, Source | - | 8098 | -0.017 | -0.2108 | No |
| 70 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 8110 | -0.017 | -0.2095 | No |
| 71 | IL13 | IL13 Entrez, Source | interleukin 13 | 8256 | -0.018 | -0.2182 | No |
| 72 | PFN1 | PFN1 Entrez, Source | profilin 1 | 8402 | -0.020 | -0.2268 | No |
| 73 | HSD3B7 | HSD3B7 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 8441 | -0.020 | -0.2272 | No |
| 74 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 8457 | -0.020 | -0.2258 | No |
| 75 | GRK5 | GRK5 Entrez, Source | G protein-coupled receptor kinase 5 | 8649 | -0.022 | -0.2375 | No |
| 76 | NFKBIB | NFKBIB Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 8711 | -0.023 | -0.2393 | No |
| 77 | GATA4 | GATA4 Entrez, Source | GATA binding protein 4 | 8719 | -0.023 | -0.2370 | No |
| 78 | DCAMKL1 | DCAMKL1 Entrez, Source | doublecortin and CaM kinase-like 1 | 8938 | -0.025 | -0.2503 | No |
| 79 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 9381 | -0.030 | -0.2800 | No |
| 80 | DAP3 | DAP3 Entrez, Source | death associated protein 3 | 9414 | -0.030 | -0.2787 | No |
| 81 | PTMS | PTMS Entrez, Source | parathymosin | 9486 | -0.031 | -0.2802 | No |
| 82 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 9571 | -0.032 | -0.2826 | No |
| 83 | ENO3 | ENO3 Entrez, Source | enolase 3 (beta, muscle) | 9845 | -0.036 | -0.2989 | No |
| 84 | GNB1 | GNB1 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 10542 | -0.044 | -0.3460 | No |
| 85 | SMOC1 | SMOC1 Entrez, Source | SPARC related modular calcium binding 1 | 10655 | -0.046 | -0.3489 | No |
| 86 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 10848 | -0.049 | -0.3574 | No |
| 87 | CXCL9 | CXCL9 Entrez, Source | chemokine (C-X-C motif) ligand 9 | 10997 | -0.051 | -0.3623 | No |
| 88 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 11323 | -0.057 | -0.3798 | No |
| 89 | RND1 | RND1 Entrez, Source | Rho family GTPase 1 | 11574 | -0.062 | -0.3910 | No |
| 90 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 11718 | -0.065 | -0.3938 | No |
| 91 | C1ORF24 | C1ORF24 Entrez, Source | chromosome 1 open reading frame 24 | 12031 | -0.074 | -0.4083 | No |
| 92 | DDR1 | DDR1 Entrez, Source | discoidin domain receptor family, member 1 | 12120 | -0.077 | -0.4055 | No |
| 93 | CPD | CPD Entrez, Source | carboxypeptidase D | 12602 | -0.097 | -0.4299 | Yes |
| 94 | BMP2K | BMP2K Entrez, Source | BMP2 inducible kinase | 12687 | -0.102 | -0.4237 | Yes |
| 95 | ARHGAP8 | ARHGAP8 Entrez, Source | Rho GTPase activating protein 8 | 12701 | -0.103 | -0.4119 | Yes |
| 96 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 12785 | -0.110 | -0.4046 | Yes |
| 97 | NFKB2 | NFKB2 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 12794 | -0.110 | -0.3917 | Yes |
| 98 | ATP1B1 | ATP1B1 Entrez, Source | ATPase, Na+/K+ transporting, beta 1 polypeptide | 13030 | -0.136 | -0.3927 | Yes |
| 99 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 13071 | -0.143 | -0.3780 | Yes |
| 100 | CXCL16 | CXCL16 Entrez, Source | chemokine (C-X-C motif) ligand 16 | 13080 | -0.146 | -0.3606 | Yes |
| 101 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 13151 | -0.163 | -0.3458 | Yes |
| 102 | FGF1 | FGF1 Entrez, Source | fibroblast growth factor 1 (acidic) | 13172 | -0.171 | -0.3263 | Yes |
| 103 | SMPD3 | SMPD3 Entrez, Source | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) | 13215 | -0.202 | -0.3045 | Yes |
| 104 | MSN | MSN Entrez, Source | moesin | 13233 | -0.213 | -0.2795 | Yes |
| 105 | IL1A | IL1A Entrez, Source | interleukin 1, alpha | 13241 | -0.218 | -0.2532 | Yes |
| 106 | LTB | LTB Entrez, Source | lymphotoxin beta (TNF superfamily, member 3) | 13250 | -0.220 | -0.2266 | Yes |
| 107 | EDG5 | EDG5 Entrez, Source | endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 | 13254 | -0.222 | -0.1995 | Yes |
| 108 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13262 | -0.231 | -0.1715 | Yes |
| 109 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 13267 | -0.235 | -0.1428 | Yes |
| 110 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13284 | -0.263 | -0.1116 | Yes |
| 111 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13295 | -0.275 | -0.0785 | Yes |
| 112 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 13310 | -0.321 | -0.0400 | Yes |
| 113 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 13315 | -0.343 | 0.0020 | Yes |
