Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | V$NRSF_01 |
| Enrichment Score (ES) | 0.4585725 |
| Normalized Enrichment Score (NES) | 1.7180973 |
| Nominal p-value | 0.00203666 |
| FDR q-value | 0.120921426 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | L1CAM | L1CAM Entrez, Source | L1 cell adhesion molecule | 245 | 0.142 | 0.0313 | Yes |
| 2 | CHKA | CHKA Entrez, Source | choline kinase alpha | 435 | 0.123 | 0.0601 | Yes |
| 3 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 619 | 0.109 | 0.0846 | Yes |
| 4 | CDK5R1 | CDK5R1 Entrez, Source | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 630 | 0.108 | 0.1218 | Yes |
| 5 | GABRG2 | GABRG2 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, gamma 2 | 804 | 0.099 | 0.1437 | Yes |
| 6 | NEFH | NEFH Entrez, Source | neurofilament, heavy polypeptide 200kDa | 1031 | 0.090 | 0.1584 | Yes |
| 7 | DRD3 | DRD3 Entrez, Source | dopamine receptor D3 | 1048 | 0.090 | 0.1886 | Yes |
| 8 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 1137 | 0.086 | 0.2121 | Yes |
| 9 | BARHL1 | BARHL1 Entrez, Source | BarH-like 1 (Drosophila) | 1630 | 0.072 | 0.2002 | Yes |
| 10 | DDX25 | DDX25 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 | 1658 | 0.071 | 0.2230 | Yes |
| 11 | ATP6V0A1 | ATP6V0A1 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a1 | 1685 | 0.070 | 0.2457 | Yes |
| 12 | TCF1 | TCF1 Entrez, Source | transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor | 1694 | 0.070 | 0.2696 | Yes |
| 13 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 1845 | 0.066 | 0.2815 | Yes |
| 14 | SLC12A5 | SLC12A5 Entrez, Source | solute carrier family 12, (potassium-chloride transporter) member 5 | 1899 | 0.065 | 0.3003 | Yes |
| 15 | CHRNB2 | CHRNB2 Entrez, Source | cholinergic receptor, nicotinic, beta 2 (neuronal) | 2101 | 0.060 | 0.3062 | Yes |
| 16 | ATP2B2 | ATP2B2 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 2 | 2135 | 0.059 | 0.3244 | Yes |
| 17 | KCNH8 | KCNH8 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 8 | 2151 | 0.059 | 0.3439 | Yes |
| 18 | LHX3 | LHX3 Entrez, Source | LIM homeobox 3 | 2204 | 0.057 | 0.3601 | Yes |
| 19 | HTR5A | HTR5A Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 5A | 2334 | 0.055 | 0.3696 | Yes |
| 20 | RASGRF1 | RASGRF1 Entrez, Source | Ras protein-specific guanine nucleotide-releasing factor 1 | 2361 | 0.054 | 0.3867 | Yes |
| 21 | HTR1A | HTR1A Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 1A | 2515 | 0.051 | 0.3932 | Yes |
| 22 | PCSK2 | PCSK2 Entrez, Source | proprotein convertase subtilisin/kexin type 2 | 2588 | 0.050 | 0.4052 | Yes |
| 23 | KCNH4 | KCNH4 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 4 | 2628 | 0.049 | 0.4196 | Yes |
| 24 | RPH3A | RPH3A Entrez, Source | rabphilin 3A homolog (mouse) | 2750 | 0.047 | 0.4270 | Yes |
| 25 | TRIM9 | TRIM9 Entrez, Source | tripartite motif-containing 9 | 2753 | 0.047 | 0.4434 | Yes |
| 26 | ELAVL3 | ELAVL3 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 2861 | 0.045 | 0.4511 | Yes |
| 27 | SNAP25 | SNAP25 Entrez, Source | synaptosomal-associated protein, 25kDa | 2966 | 0.044 | 0.4586 | Yes |
| 28 | APBB1 | APBB1 Entrez, Source | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 3442 | 0.036 | 0.4355 | No |
| 29 | SEZ6 | SEZ6 Entrez, Source | seizure related 6 homolog (mouse) | 3603 | 0.034 | 0.4353 | No |
| 30 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 3670 | 0.033 | 0.4418 | No |
| 31 | HCN1 | HCN1 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 1 | 3809 | 0.031 | 0.4422 | No |
| 32 | PTPRN | PTPRN Entrez, Source | protein tyrosine phosphatase, receptor type, N | 3909 | 0.030 | 0.4452 | No |
| 33 | DRD2 | DRD2 Entrez, Source | dopamine receptor D2 | 4082 | 0.027 | 0.4417 | No |
| 34 | GLRA1 | GLRA1 Entrez, Source | glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome) | 4330 | 0.024 | 0.4316 | No |
| 35 | SYT6 | SYT6 Entrez, Source | synaptotagmin VI | 4551 | 0.021 | 0.4225 | No |
| 36 | GRM1 | GRM1 Entrez, Source | glutamate receptor, metabotropic 1 | 4558 | 0.021 | 0.4295 | No |
| 37 | DBC1 | DBC1 Entrez, Source | deleted in bladder cancer 1 | 5374 | 0.012 | 0.3722 | No |
| 38 | TMEM22 | TMEM22 Entrez, Source | transmembrane protein 22 | 5540 | 0.010 | 0.3632 | No |
| 39 | FGF12 | FGF12 Entrez, Source | fibroblast growth factor 12 | 5771 | 0.007 | 0.3484 | No |
| 40 | CHGA | CHGA Entrez, Source | chromogranin A (parathyroid secretory protein 1) | 5849 | 0.006 | 0.3447 | No |
| 41 | KCNIP2 | KCNIP2 Entrez, Source | Kv channel interacting protein 2 | 5898 | 0.006 | 0.3430 | No |
| 42 | SST | SST Entrez, Source | somatostatin | 5930 | 0.005 | 0.3425 | No |
| 43 | SCN3B | SCN3B Entrez, Source | sodium channel, voltage-gated, type III, beta | 6114 | 0.003 | 0.3300 | No |
| 44 | CSPG3 | CSPG3 Entrez, Source | chondroitin sulfate proteoglycan 3 (neurocan) | 6123 | 0.003 | 0.3306 | No |
| 45 | STMN2 | STMN2 Entrez, Source | stathmin-like 2 | 6372 | 0.001 | 0.3121 | No |
| 46 | SYT4 | SYT4 Entrez, Source | synaptotagmin IV | 6412 | 0.000 | 0.3092 | No |
| 47 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 6747 | -0.003 | 0.2852 | No |
| 48 | POMC | POMC Entrez, Source | proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin) | 6798 | -0.004 | 0.2827 | No |
| 49 | CRYBA2 | CRYBA2 Entrez, Source | crystallin, beta A2 | 7399 | -0.010 | 0.2409 | No |
| 50 | NPPB | NPPB Entrez, Source | natriuretic peptide precursor B | 7667 | -0.012 | 0.2251 | No |
| 51 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 7868 | -0.014 | 0.2150 | No |
| 52 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 7999 | -0.016 | 0.2107 | No |
| 53 | GHSR | GHSR Entrez, Source | growth hormone secretagogue receptor | 8118 | -0.017 | 0.2077 | No |
| 54 | OMG | OMG Entrez, Source | oligodendrocyte myelin glycoprotein | 8432 | -0.020 | 0.1911 | No |
| 55 | CALB1 | CALB1 Entrez, Source | calbindin 1, 28kDa | 9321 | -0.029 | 0.1345 | No |
| 56 | GRIN1 | GRIN1 Entrez, Source | glutamate receptor, ionotropic, N-methyl D-aspartate 1 | 10477 | -0.043 | 0.0626 | No |
| 57 | SLC17A6 | SLC17A6 Entrez, Source | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 | 11560 | -0.062 | 0.0028 | No |
| 58 | VIP | VIP Entrez, Source | vasoactive intestinal peptide | 11599 | -0.062 | 0.0218 | No |
| 59 | COL5A3 | COL5A3 Entrez, Source | collagen, type V, alpha 3 | 11947 | -0.071 | 0.0206 | No |
| 60 | SCAMP5 | SCAMP5 Entrez, Source | secretory carrier membrane protein 5 | 12035 | -0.074 | 0.0400 | No |
| 61 | NEF3 | NEF3 Entrez, Source | neurofilament 3 (150kDa medium) | 12248 | -0.081 | 0.0524 | No |
| 62 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 12350 | -0.085 | 0.0747 | No |
