Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | V$SRF_Q4 |
| Enrichment Score (ES) | -0.37190908 |
| Normalized Enrichment Score (NES) | -1.5737071 |
| Nominal p-value | 0.007677543 |
| FDR q-value | 0.25632846 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 10 | 0.347 | 0.0374 | No |
| 2 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 11 | 0.331 | 0.0738 | No |
| 3 | EGR1 | EGR1 Entrez, Source | early growth response 1 | 35 | 0.229 | 0.0973 | No |
| 4 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 41 | 0.224 | 0.1216 | No |
| 5 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 206 | 0.148 | 0.1255 | No |
| 6 | CKM | CKM Entrez, Source | creatine kinase, muscle | 445 | 0.122 | 0.1209 | No |
| 7 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 500 | 0.118 | 0.1298 | No |
| 8 | FST | FST Entrez, Source | follistatin | 503 | 0.117 | 0.1426 | No |
| 9 | IER2 | IER2 Entrez, Source | immediate early response 2 | 528 | 0.115 | 0.1534 | No |
| 10 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 612 | 0.109 | 0.1591 | No |
| 11 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 619 | 0.109 | 0.1707 | No |
| 12 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 731 | 0.103 | 0.1736 | No |
| 13 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 816 | 0.099 | 0.1781 | No |
| 14 | CX3CL1 | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 894 | 0.096 | 0.1828 | No |
| 15 | DUSP2 | DUSP2 Entrez, Source | dual specificity phosphatase 2 | 1238 | 0.082 | 0.1659 | No |
| 16 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 1427 | 0.077 | 0.1602 | No |
| 17 | GAB2 | GAB2 Entrez, Source | GRB2-associated binding protein 2 | 1477 | 0.075 | 0.1648 | No |
| 18 | SDPR | SDPR Entrez, Source | serum deprivation response (phosphatidylserine binding protein) | 1545 | 0.074 | 0.1678 | No |
| 19 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 1628 | 0.072 | 0.1695 | No |
| 20 | FOXE3 | FOXE3 Entrez, Source | forkhead box E3 | 1801 | 0.067 | 0.1639 | No |
| 21 | RASD2 | RASD2 Entrez, Source | RASD family, member 2 | 1830 | 0.067 | 0.1691 | No |
| 22 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 2040 | 0.061 | 0.1601 | No |
| 23 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 2132 | 0.059 | 0.1597 | No |
| 24 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 2450 | 0.053 | 0.1415 | No |
| 25 | DGKG | DGKG Entrez, Source | diacylglycerol kinase, gamma 90kDa | 2521 | 0.051 | 0.1419 | No |
| 26 | NLGN3 | NLGN3 Entrez, Source | neuroligin 3 | 2541 | 0.051 | 0.1460 | No |
| 27 | POU3F4 | POU3F4 Entrez, Source | POU domain, class 3, transcription factor 4 | 2551 | 0.051 | 0.1509 | No |
| 28 | KCNMB1 | KCNMB1 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, beta member 1 | 2672 | 0.049 | 0.1472 | No |
| 29 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 2706 | 0.048 | 0.1500 | No |
| 30 | SORT1 | SORT1 Entrez, Source | sortilin 1 | 2881 | 0.045 | 0.1417 | No |
| 31 | JPH2 | JPH2 Entrez, Source | junctophilin 2 | 2958 | 0.044 | 0.1408 | No |
| 32 | MRGPRF | MRGPRF Entrez, Source | MAS-related GPR, member F | 3328 | 0.038 | 0.1171 | No |
| 33 | MSX1 | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 3576 | 0.034 | 0.1022 | No |
| 34 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 3593 | 0.034 | 0.1047 | No |
| 35 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 3699 | 0.033 | 0.1003 | No |
| 36 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 3724 | 0.032 | 0.1020 | No |
| 37 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 3752 | 0.032 | 0.1035 | No |
| 38 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 3835 | 0.031 | 0.1007 | No |
| 39 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 3853 | 0.030 | 0.1027 | No |
| 40 | FGFRL1 | FGFRL1 Entrez, Source | fibroblast growth factor receptor-like 1 | 3953 | 0.029 | 0.0984 | No |
| 41 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 4037 | 0.028 | 0.0952 | No |
| 42 | ESRRA | ESRRA Entrez, Source | estrogen-related receptor alpha | 4249 | 0.025 | 0.0820 | No |
| 43 | NPPA | NPPA Entrez, Source | natriuretic peptide precursor A | 4369 | 0.024 | 0.0756 | No |
| 44 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 4572 | 0.021 | 0.0627 | No |
| 45 | CRH | CRH Entrez, Source | corticotropin releasing hormone | 4615 | 0.021 | 0.0618 | No |
| 46 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 4956 | 0.016 | 0.0379 | No |
| 47 | TGIF | TGIF Entrez, Source | TGFB-induced factor (TALE family homeobox) | 5050 | 0.015 | 0.0325 | No |
| 48 | SRP54 | SRP54 Entrez, Source | signal recognition particle 54kDa | 5133 | 0.015 | 0.0279 | No |
| 49 | EGR4 | EGR4 Entrez, Source | early growth response 4 | 5233 | 0.013 | 0.0219 | No |
| 50 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5303 | 0.013 | 0.0181 | No |
| 51 | GPR20 | GPR20 Entrez, Source | G protein-coupled receptor 20 | 5370 | 0.012 | 0.0144 | No |
| 52 | FGF8 | FGF8 Entrez, Source | fibroblast growth factor 8 (androgen-induced) | 5489 | 0.010 | 0.0066 | No |
| 53 | FGF17 | FGF17 Entrez, Source | fibroblast growth factor 17 | 5630 | 0.009 | -0.0030 | No |
| 54 | SLC4A3 | SLC4A3 Entrez, Source | solute carrier family 4, anion exchanger, member 3 | 5718 | 0.008 | -0.0088 | No |
| 55 | MCL1 | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 5839 | 0.006 | -0.0172 | No |
| 56 | TNMD | TNMD Entrez, Source | tenomodulin | 5995 | 0.005 | -0.0284 | No |
| 57 | IHPK1 | IHPK1 Entrez, Source | inositol hexaphosphate kinase 1 | 6467 | -0.000 | -0.0639 | No |
| 58 | MAP1A | MAP1A Entrez, Source | microtubule-associated protein 1A | 6569 | -0.002 | -0.0714 | No |
| 59 | CACNA1B | CACNA1B Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1B subunit | 6647 | -0.002 | -0.0769 | No |
| 60 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 6688 | -0.003 | -0.0796 | No |
| 61 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 6719 | -0.003 | -0.0816 | No |
| 62 | COL23A1 | COL23A1 Entrez, Source | collagen, type XXIII, alpha 1 | 6730 | -0.003 | -0.0820 | No |
| 63 | MYO1B | MYO1B Entrez, Source | myosin IB | 6819 | -0.004 | -0.0882 | No |
| 64 | RIMS1 | RIMS1 Entrez, Source | regulating synaptic membrane exocytosis 1 | 7006 | -0.006 | -0.1017 | No |
| 65 | IL17B | IL17B Entrez, Source | interleukin 17B | 7271 | -0.008 | -0.1207 | No |
| 66 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 7287 | -0.009 | -0.1209 | No |
| 67 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 7532 | -0.011 | -0.1382 | No |
| 68 | SND1 | SND1 Entrez, Source | - | 7653 | -0.012 | -0.1459 | No |
| 69 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 7684 | -0.012 | -0.1468 | No |
| 70 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 7768 | -0.013 | -0.1516 | No |
| 71 | CNN1 | CNN1 Entrez, Source | calponin 1, basic, smooth muscle | 7985 | -0.015 | -0.1663 | No |
| 72 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 8057 | -0.016 | -0.1698 | No |
| 73 | ACTB | ACTB Entrez, Source | actin, beta | 8105 | -0.017 | -0.1716 | No |
| 74 | RERE | RERE Entrez, Source | arginine-glutamic acid dipeptide (RE) repeats | 8291 | -0.019 | -0.1835 | No |
| 75 | PFN1 | PFN1 Entrez, Source | profilin 1 | 8402 | -0.020 | -0.1897 | No |
| 76 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 8491 | -0.021 | -0.1940 | No |
| 77 | TAF5L | TAF5L Entrez, Source | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | 8746 | -0.023 | -0.2107 | No |
| 78 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 9056 | -0.027 | -0.2311 | No |
| 79 | RHOJ | RHOJ Entrez, Source | ras homolog gene family, member J | 9147 | -0.027 | -0.2349 | No |
| 80 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 9251 | -0.029 | -0.2396 | No |
| 81 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 9335 | -0.029 | -0.2426 | No |
| 82 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 9696 | -0.034 | -0.2661 | No |
| 83 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 9749 | -0.034 | -0.2662 | No |
| 84 | DLL1 | DLL1 Entrez, Source | delta-like 1 (Drosophila) | 9837 | -0.036 | -0.2689 | No |
| 85 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 9889 | -0.036 | -0.2688 | No |
| 86 | FOXP1 | FOXP1 Entrez, Source | forkhead box P1 | 9904 | -0.036 | -0.2659 | No |
| 87 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 10033 | -0.038 | -0.2714 | No |
| 88 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 10067 | -0.038 | -0.2697 | No |
| 89 | PLCB3 | PLCB3 Entrez, Source | phospholipase C, beta 3 (phosphatidylinositol-specific) | 10097 | -0.038 | -0.2677 | No |
| 90 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 10571 | -0.044 | -0.2986 | No |
| 91 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 10717 | -0.047 | -0.3044 | No |
| 92 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 10896 | -0.050 | -0.3124 | No |
| 93 | MYO1E | MYO1E Entrez, Source | myosin IE | 10936 | -0.050 | -0.3099 | No |
| 94 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 11026 | -0.051 | -0.3109 | No |
| 95 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 11245 | -0.056 | -0.3213 | No |
| 96 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 11497 | -0.060 | -0.3336 | No |
| 97 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 11521 | -0.061 | -0.3287 | No |
| 98 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 11744 | -0.066 | -0.3382 | No |
| 99 | TMOD1 | TMOD1 Entrez, Source | tropomodulin 1 | 11873 | -0.069 | -0.3403 | No |
| 100 | KCNJ13 | KCNJ13 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 13 | 11913 | -0.070 | -0.3355 | No |
| 101 | MUS81 | MUS81 Entrez, Source | MUS81 endonuclease homolog (S. cerevisiae) | 12171 | -0.078 | -0.3464 | No |
| 102 | GRK6 | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 12510 | -0.092 | -0.3618 | Yes |
| 103 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 12565 | -0.095 | -0.3554 | Yes |
| 104 | ACTG2 | ACTG2 Entrez, Source | actin, gamma 2, smooth muscle, enteric | 12642 | -0.099 | -0.3503 | Yes |
| 105 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 12660 | -0.100 | -0.3406 | Yes |
| 106 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 12799 | -0.110 | -0.3389 | Yes |
| 107 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 12899 | -0.121 | -0.3331 | Yes |
| 108 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12937 | -0.125 | -0.3221 | Yes |
| 109 | DIXDC1 | DIXDC1 Entrez, Source | DIX domain containing 1 | 13065 | -0.142 | -0.3160 | Yes |
| 110 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 13146 | -0.160 | -0.3045 | Yes |
| 111 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 13152 | -0.163 | -0.2869 | Yes |
| 112 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13284 | -0.263 | -0.2679 | Yes |
| 113 | SERPINH1 | SERPINH1 Entrez, Source | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 13285 | -0.265 | -0.2388 | Yes |
| 114 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13295 | -0.275 | -0.2093 | Yes |
| 115 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13320 | -0.362 | -0.1713 | Yes |
| 116 | TAGLN | TAGLN Entrez, Source | transgelin | 13340 | -0.666 | -0.0995 | Yes |
| 117 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -0.905 | -0.0000 | Yes |
