Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | V$SRF_Q5_01 |
| Enrichment Score (ES) | -0.3632787 |
| Normalized Enrichment Score (NES) | -1.51309 |
| Nominal p-value | 0.012578616 |
| FDR q-value | 0.27870992 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 10 | 0.347 | 0.0363 | No |
| 2 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 11 | 0.331 | 0.0716 | No |
| 3 | PLN | PLN Entrez, Source | phospholamban | 12 | 0.308 | 0.1045 | No |
| 4 | EGR1 | EGR1 Entrez, Source | early growth response 1 | 35 | 0.229 | 0.1273 | No |
| 5 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 41 | 0.224 | 0.1508 | No |
| 6 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 206 | 0.148 | 0.1543 | No |
| 7 | CKM | CKM Entrez, Source | creatine kinase, muscle | 445 | 0.122 | 0.1493 | No |
| 8 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 500 | 0.118 | 0.1578 | No |
| 9 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 502 | 0.118 | 0.1703 | No |
| 10 | IER2 | IER2 Entrez, Source | immediate early response 2 | 528 | 0.115 | 0.1807 | No |
| 11 | SLC2A4 | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 562 | 0.113 | 0.1903 | No |
| 12 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 612 | 0.109 | 0.1982 | No |
| 13 | SLC16A6 | SLC16A6 Entrez, Source | solute carrier family 16, member 6 (monocarboxylic acid transporter 7) | 674 | 0.105 | 0.2049 | No |
| 14 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 731 | 0.103 | 0.2116 | No |
| 15 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 816 | 0.099 | 0.2159 | No |
| 16 | SDPR | SDPR Entrez, Source | serum deprivation response (phosphatidylserine binding protein) | 1545 | 0.074 | 0.1687 | No |
| 17 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 1609 | 0.072 | 0.1716 | No |
| 18 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 1628 | 0.072 | 0.1779 | No |
| 19 | TRDN | TRDN Entrez, Source | triadin | 1668 | 0.071 | 0.1825 | No |
| 20 | FGF7 | FGF7 Entrez, Source | fibroblast growth factor 7 (keratinocyte growth factor) | 1778 | 0.068 | 0.1816 | No |
| 21 | FOXE3 | FOXE3 Entrez, Source | forkhead box E3 | 1801 | 0.067 | 0.1871 | No |
| 22 | FLNC | FLNC Entrez, Source | filamin C, gamma (actin binding protein 280) | 1809 | 0.067 | 0.1937 | No |
| 23 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 1832 | 0.067 | 0.1992 | No |
| 24 | GGN | GGN Entrez, Source | gametogenetin | 1864 | 0.066 | 0.2039 | No |
| 25 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 2040 | 0.061 | 0.1972 | No |
| 26 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 2132 | 0.059 | 0.1967 | No |
| 27 | PRKAB2 | PRKAB2 Entrez, Source | protein kinase, AMP-activated, beta 2 non-catalytic subunit | 2229 | 0.057 | 0.1955 | No |
| 28 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 2302 | 0.055 | 0.1959 | No |
| 29 | ASB2 | ASB2 Entrez, Source | ankyrin repeat and SOCS box-containing 2 | 2403 | 0.054 | 0.1941 | No |
| 30 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 2450 | 0.053 | 0.1963 | No |
| 31 | DGKG | DGKG Entrez, Source | diacylglycerol kinase, gamma 90kDa | 2521 | 0.051 | 0.1964 | No |
| 32 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 2706 | 0.048 | 0.1877 | No |
| 33 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 2787 | 0.046 | 0.1866 | No |
| 34 | NFATC4 | NFATC4 Entrez, Source | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 3046 | 0.042 | 0.1716 | No |
| 35 | KCNH2 | KCNH2 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 3257 | 0.039 | 0.1599 | No |
| 36 | MRGPRF | MRGPRF Entrez, Source | MAS-related GPR, member F | 3328 | 0.038 | 0.1587 | No |
| 37 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 3467 | 0.036 | 0.1520 | No |
| 38 | OTX1 | OTX1 Entrez, Source | orthodenticle homolog 1 (Drosophila) | 3509 | 0.035 | 0.1527 | No |
| 39 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 3593 | 0.034 | 0.1500 | No |
| 40 | NRXN3 | NRXN3 Entrez, Source | neurexin 3 | 3655 | 0.033 | 0.1490 | No |
| 41 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 3724 | 0.032 | 0.1473 | No |
| 42 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 3752 | 0.032 | 0.1486 | No |
| 43 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 3853 | 0.030 | 0.1443 | No |
| 44 | FGFRL1 | FGFRL1 Entrez, Source | fibroblast growth factor receptor-like 1 | 3953 | 0.029 | 0.1399 | No |
| 45 | NPPA | NPPA Entrez, Source | natriuretic peptide precursor A | 4369 | 0.024 | 0.1111 | No |
| 46 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 4572 | 0.021 | 0.0981 | No |
| 47 | CRH | CRH Entrez, Source | corticotropin releasing hormone | 4615 | 0.021 | 0.0971 | No |
| 48 | GPR20 | GPR20 Entrez, Source | G protein-coupled receptor 20 | 5370 | 0.012 | 0.0413 | No |
| 49 | FGF8 | FGF8 Entrez, Source | fibroblast growth factor 8 (androgen-induced) | 5489 | 0.010 | 0.0335 | No |
| 50 | FGF17 | FGF17 Entrez, Source | fibroblast growth factor 17 | 5630 | 0.009 | 0.0239 | No |
| 51 | SLC4A3 | SLC4A3 Entrez, Source | solute carrier family 4, anion exchanger, member 3 | 5718 | 0.008 | 0.0181 | No |
| 52 | TNMD | TNMD Entrez, Source | tenomodulin | 5995 | 0.005 | -0.0022 | No |
| 53 | MAP1A | MAP1A Entrez, Source | microtubule-associated protein 1A | 6569 | -0.002 | -0.0454 | No |
| 54 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6594 | -0.002 | -0.0470 | No |
| 55 | CACNA1B | CACNA1B Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1B subunit | 6647 | -0.002 | -0.0506 | No |
| 56 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 6688 | -0.003 | -0.0534 | No |
| 57 | COL23A1 | COL23A1 Entrez, Source | collagen, type XXIII, alpha 1 | 6730 | -0.003 | -0.0561 | No |
| 58 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 6743 | -0.003 | -0.0567 | No |
| 59 | RIMS1 | RIMS1 Entrez, Source | regulating synaptic membrane exocytosis 1 | 7006 | -0.006 | -0.0759 | No |
| 60 | IL17B | IL17B Entrez, Source | interleukin 17B | 7271 | -0.008 | -0.0949 | No |
| 61 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 7287 | -0.009 | -0.0952 | No |
| 62 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 7532 | -0.011 | -0.1124 | No |
| 63 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 7768 | -0.013 | -0.1288 | No |
| 64 | CNN1 | CNN1 Entrez, Source | calponin 1, basic, smooth muscle | 7985 | -0.015 | -0.1434 | No |
| 65 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 8057 | -0.016 | -0.1471 | No |
| 66 | ACTB | ACTB Entrez, Source | actin, beta | 8105 | -0.017 | -0.1488 | No |
| 67 | RERE | RERE Entrez, Source | arginine-glutamic acid dipeptide (RE) repeats | 8291 | -0.019 | -0.1608 | No |
| 68 | PFN1 | PFN1 Entrez, Source | profilin 1 | 8402 | -0.020 | -0.1670 | No |
| 69 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 8491 | -0.021 | -0.1715 | No |
| 70 | ITGB6 | ITGB6 Entrez, Source | integrin, beta 6 | 8714 | -0.023 | -0.1858 | No |
| 71 | TAF5L | TAF5L Entrez, Source | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | 8746 | -0.023 | -0.1857 | No |
| 72 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 9056 | -0.027 | -0.2062 | No |
| 73 | RHOJ | RHOJ Entrez, Source | ras homolog gene family, member J | 9147 | -0.027 | -0.2100 | No |
| 74 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 9251 | -0.029 | -0.2148 | No |
| 75 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 9335 | -0.029 | -0.2179 | No |
| 76 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 9696 | -0.034 | -0.2415 | No |
| 77 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 9749 | -0.034 | -0.2417 | No |
| 78 | DLL1 | DLL1 Entrez, Source | delta-like 1 (Drosophila) | 9837 | -0.036 | -0.2445 | No |
| 79 | ACTR3 | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 9840 | -0.036 | -0.2409 | No |
| 80 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 9889 | -0.036 | -0.2407 | No |
| 81 | FOXP1 | FOXP1 Entrez, Source | forkhead box P1 | 9904 | -0.036 | -0.2379 | No |
| 82 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 10067 | -0.038 | -0.2460 | No |
| 83 | PLCB3 | PLCB3 Entrez, Source | phospholipase C, beta 3 (phosphatidylinositol-specific) | 10097 | -0.038 | -0.2441 | No |
| 84 | PDLIM7 | PDLIM7 Entrez, Source | PDZ and LIM domain 7 (enigma) | 10511 | -0.044 | -0.2707 | No |
| 85 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 10717 | -0.047 | -0.2812 | No |
| 86 | MYO1E | MYO1E Entrez, Source | myosin IE | 10936 | -0.050 | -0.2923 | No |
| 87 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 11026 | -0.051 | -0.2936 | No |
| 88 | NRAS | NRAS Entrez, Source | neuroblastoma RAS viral (v-ras) oncogene homolog | 11369 | -0.058 | -0.3132 | No |
| 89 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 11497 | -0.060 | -0.3164 | No |
| 90 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 11521 | -0.061 | -0.3116 | No |
| 91 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 11744 | -0.066 | -0.3214 | No |
| 92 | TRIM3 | TRIM3 Entrez, Source | tripartite motif-containing 3 | 11874 | -0.069 | -0.3237 | No |
| 93 | MUS81 | MUS81 Entrez, Source | MUS81 endonuclease homolog (S. cerevisiae) | 12171 | -0.078 | -0.3377 | No |
| 94 | GRK6 | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 12510 | -0.092 | -0.3535 | Yes |
| 95 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 12540 | -0.094 | -0.3457 | Yes |
| 96 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 12565 | -0.095 | -0.3374 | Yes |
| 97 | ACTG2 | ACTG2 Entrez, Source | actin, gamma 2, smooth muscle, enteric | 12642 | -0.099 | -0.3325 | Yes |
| 98 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 12660 | -0.100 | -0.3232 | Yes |
| 99 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 12799 | -0.110 | -0.3218 | Yes |
| 100 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 12899 | -0.121 | -0.3164 | Yes |
| 101 | LCP1 | LCP1 Entrez, Source | lymphocyte cytosolic protein 1 (L-plastin) | 13041 | -0.138 | -0.3122 | Yes |
| 102 | DIXDC1 | DIXDC1 Entrez, Source | DIX domain containing 1 | 13065 | -0.142 | -0.2988 | Yes |
| 103 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 13152 | -0.163 | -0.2879 | Yes |
| 104 | MYADM | MYADM Entrez, Source | myeloid-associated differentiation marker | 13269 | -0.239 | -0.2711 | Yes |
| 105 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13295 | -0.275 | -0.2437 | Yes |
| 106 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13320 | -0.362 | -0.2069 | Yes |
| 107 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13324 | -0.380 | -0.1665 | Yes |
| 108 | TAGLN | TAGLN Entrez, Source | transgelin | 13340 | -0.666 | -0.0965 | Yes |
| 109 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -0.905 | 0.0000 | Yes |
