Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | WIELAND_HEPATITIS_B_INDUCED |
| Enrichment Score (ES) | -0.47791824 |
| Normalized Enrichment Score (NES) | -1.7638342 |
| Nominal p-value | 0.0019417476 |
| FDR q-value | 0.13493097 |
| FWER p-Value | 0.992 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CD3D | CD3D Entrez, Source | CD3d molecule, delta (CD3-TCR complex) | 339 | 0.131 | 0.0059 | No |
| 2 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 347 | 0.130 | 0.0367 | No |
| 3 | TYROBP | TYROBP Entrez, Source | TYRO protein tyrosine kinase binding protein | 376 | 0.128 | 0.0654 | No |
| 4 | GIMAP5 | GIMAP5 Entrez, Source | GTPase, IMAP family member 5 | 888 | 0.096 | 0.0499 | No |
| 5 | LAPTM5 | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 1212 | 0.083 | 0.0456 | No |
| 6 | LPXN | LPXN Entrez, Source | leupaxin | 1452 | 0.076 | 0.0460 | No |
| 7 | CD38 | CD38 Entrez, Source | CD38 molecule | 1632 | 0.072 | 0.0497 | No |
| 8 | CD53 | CD53 Entrez, Source | CD53 molecule | 2526 | 0.051 | -0.0052 | No |
| 9 | PTTG1 | PTTG1 Entrez, Source | pituitary tumor-transforming 1 | 2878 | 0.045 | -0.0209 | No |
| 10 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 2879 | 0.045 | -0.0101 | No |
| 11 | HLA-DMB | HLA-DMB Entrez, Source | major histocompatibility complex, class II, DM beta | 3647 | 0.033 | -0.0598 | No |
| 12 | CD68 | CD68 Entrez, Source | CD68 molecule | 3671 | 0.033 | -0.0537 | No |
| 13 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 3877 | 0.030 | -0.0619 | No |
| 14 | IL10RA | IL10RA Entrez, Source | interleukin 10 receptor, alpha | 3942 | 0.029 | -0.0597 | No |
| 15 | CD74 | CD74 Entrez, Source | CD74 molecule, major histocompatibility complex, class II invariant chain | 4100 | 0.027 | -0.0650 | No |
| 16 | LAP3 | LAP3 Entrez, Source | leucine aminopeptidase 3 | 4119 | 0.027 | -0.0600 | No |
| 17 | FGL2 | FGL2 Entrez, Source | fibrinogen-like 2 | 4253 | 0.025 | -0.0639 | No |
| 18 | C3AR1 | C3AR1 Entrez, Source | complement component 3a receptor 1 | 4527 | 0.021 | -0.0793 | No |
| 19 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 4601 | 0.021 | -0.0798 | No |
| 20 | C1QB | C1QB Entrez, Source | complement component 1, q subcomponent, B chain | 4891 | 0.018 | -0.0973 | No |
| 21 | GZMA | GZMA Entrez, Source | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 5197 | 0.014 | -0.1170 | No |
| 22 | GZMK | GZMK Entrez, Source | granzyme K (granzyme 3; tryptase II) | 5359 | 0.012 | -0.1263 | No |
| 23 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 6361 | 0.001 | -0.2015 | No |
| 24 | HLA-DMA | HLA-DMA Entrez, Source | major histocompatibility complex, class II, DM alpha | 6488 | -0.001 | -0.2108 | No |
| 25 | UCP2 | UCP2 Entrez, Source | uncoupling protein 2 (mitochondrial, proton carrier) | 6742 | -0.003 | -0.2291 | No |
| 26 | B2M | B2M Entrez, Source | beta-2-microglobulin | 6897 | -0.005 | -0.2396 | No |
| 27 | GM2A | GM2A Entrez, Source | GM2 ganglioside activator | 7133 | -0.007 | -0.2556 | No |
| 28 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 7175 | -0.007 | -0.2569 | No |
| 29 | ISG20 | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 7292 | -0.009 | -0.2636 | No |
| 30 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 7778 | -0.013 | -0.2969 | No |
| 31 | WARS | WARS Entrez, Source | tryptophanyl-tRNA synthetase | 7827 | -0.014 | -0.2972 | No |
| 32 | CD48 | CD48 Entrez, Source | CD48 molecule | 7841 | -0.014 | -0.2948 | No |
| 33 | CTSB | CTSB Entrez, Source | cathepsin B | 8382 | -0.019 | -0.3308 | No |
| 34 | IGSF6 | IGSF6 Entrez, Source | immunoglobulin superfamily, member 6 | 8396 | -0.020 | -0.3270 | No |
| 35 | SLC7A7 | SLC7A7 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 | 8722 | -0.023 | -0.3460 | No |
| 36 | TPP1 | TPP1 Entrez, Source | tripeptidyl peptidase I | 9225 | -0.028 | -0.3770 | No |
| 37 | AURKA | AURKA Entrez, Source | aurora kinase A | 9667 | -0.034 | -0.4021 | No |
| 38 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 9696 | -0.034 | -0.3960 | No |
| 39 | SP110 | SP110 Entrez, Source | SP110 nuclear body protein | 9788 | -0.035 | -0.3945 | No |
| 40 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 10072 | -0.038 | -0.4066 | No |
| 41 | UBE2L6 | UBE2L6 Entrez, Source | ubiquitin-conjugating enzyme E2L 6 | 10532 | -0.044 | -0.4306 | No |
| 42 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 10707 | -0.046 | -0.4326 | No |
| 43 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 10939 | -0.050 | -0.4379 | No |
| 44 | CXCL9 | CXCL9 Entrez, Source | chemokine (C-X-C motif) ligand 9 | 10997 | -0.051 | -0.4299 | No |
| 45 | PPT1 | PPT1 Entrez, Source | palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) | 11303 | -0.057 | -0.4392 | No |
| 46 | PSME2 | PSME2 Entrez, Source | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 11462 | -0.060 | -0.4367 | No |
| 47 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 11713 | -0.065 | -0.4399 | No |
| 48 | CTSC | CTSC Entrez, Source | cathepsin C | 11993 | -0.073 | -0.4434 | No |
| 49 | TAPBP | TAPBP Entrez, Source | TAP binding protein (tapasin) | 12433 | -0.088 | -0.4553 | Yes |
| 50 | TYMS | TYMS Entrez, Source | thymidylate synthetase | 12735 | -0.105 | -0.4526 | Yes |
| 51 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 12814 | -0.112 | -0.4316 | Yes |
| 52 | PSMB9 | PSMB9 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 12830 | -0.113 | -0.4056 | Yes |
| 53 | PSMB10 | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 12966 | -0.128 | -0.3851 | Yes |
| 54 | CD5L | CD5L Entrez, Source | CD5 molecule-like | 13064 | -0.142 | -0.3582 | Yes |
| 55 | RAB27A | RAB27A Entrez, Source | RAB27A, member RAS oncogene family | 13087 | -0.147 | -0.3245 | Yes |
| 56 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13196 | -0.186 | -0.2879 | Yes |
| 57 | EMR1 | EMR1 Entrez, Source | egf-like module containing, mucin-like, hormone receptor-like 1 | 13220 | -0.205 | -0.2402 | Yes |
| 58 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 13310 | -0.321 | -0.1696 | Yes |
| 59 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 13315 | -0.343 | -0.0874 | Yes |
| 60 | GBP2 | GBP2 Entrez, Source | guanylate binding protein 2, interferon-inducible | 13323 | -0.371 | 0.0014 | Yes |
