Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | single_gel_24h |
| GeneSet | YAGI_AML_PROG_FAB |
| Enrichment Score (ES) | -0.3950206 |
| Normalized Enrichment Score (NES) | -1.653329 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.19129834 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HMGCS1 | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 36 | 0.229 | 0.0312 | No |
| 2 | HDGFRP3 | HDGFRP3 Entrez, Source | - | 241 | 0.142 | 0.0369 | No |
| 3 | MLLT11 | MLLT11 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 295 | 0.136 | 0.0530 | No |
| 4 | GP1BB /// SEPT5 | 299 | 0.135 | 0.0729 | No | ||
| 5 | DHCR24 | DHCR24 Entrez, Source | 24-dehydrocholesterol reductase | 308 | 0.134 | 0.0922 | No |
| 6 | SQLE | SQLE Entrez, Source | squalene epoxidase | 634 | 0.108 | 0.0836 | No |
| 7 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 655 | 0.107 | 0.0979 | No |
| 8 | NR4A2 | NR4A2 Entrez, Source | nuclear receptor subfamily 4, group A, member 2 | 1011 | 0.091 | 0.0846 | No |
| 9 | GABRE | GABRE Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, epsilon | 1285 | 0.081 | 0.0759 | No |
| 10 | CASP1 | CASP1 Entrez, Source | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 1348 | 0.079 | 0.0829 | No |
| 11 | SERPINI1 | SERPINI1 Entrez, Source | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 1615 | 0.072 | 0.0735 | No |
| 12 | GATA2 | GATA2 Entrez, Source | GATA binding protein 2 | 1755 | 0.069 | 0.0732 | No |
| 13 | LGALS1 | LGALS1 Entrez, Source | lectin, galactoside-binding, soluble, 1 (galectin 1) | 1865 | 0.066 | 0.0747 | No |
| 14 | LAMA5 | LAMA5 Entrez, Source | laminin, alpha 5 | 1975 | 0.063 | 0.0758 | No |
| 15 | ICAM2 | ICAM2 Entrez, Source | intercellular adhesion molecule 2 | 2246 | 0.056 | 0.0638 | No |
| 16 | NR4A3 | NR4A3 Entrez, Source | nuclear receptor subfamily 4, group A, member 3 | 2506 | 0.051 | 0.0518 | No |
| 17 | TNFRSF4 | TNFRSF4 Entrez, Source | tumor necrosis factor receptor superfamily, member 4 | 2639 | 0.049 | 0.0491 | No |
| 18 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 2833 | 0.046 | 0.0413 | No |
| 19 | SCP2 | SCP2 Entrez, Source | sterol carrier protein 2 | 3048 | 0.042 | 0.0314 | No |
| 20 | CD200 | CD200 Entrez, Source | CD200 molecule | 3078 | 0.042 | 0.0354 | No |
| 21 | RHAG | RHAG Entrez, Source | Rh-associated glycoprotein | 3123 | 0.041 | 0.0382 | No |
| 22 | TIMP2 | TIMP2 Entrez, Source | TIMP metallopeptidase inhibitor 2 | 3227 | 0.040 | 0.0363 | No |
| 23 | CTR9 | CTR9 Entrez, Source | Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 3230 | 0.040 | 0.0420 | No |
| 24 | NTRK1 | NTRK1 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 1 | 3308 | 0.038 | 0.0419 | No |
| 25 | ELL2 | ELL2 Entrez, Source | elongation factor, RNA polymerase II, 2 | 3417 | 0.036 | 0.0391 | No |
| 26 | TM7SF2 | TM7SF2 Entrez, Source | transmembrane 7 superfamily member 2 | 3630 | 0.033 | 0.0280 | No |
| 27 | CD68 | CD68 Entrez, Source | CD68 molecule | 3671 | 0.033 | 0.0299 | No |
| 28 | TGM2 | TGM2 Entrez, Source | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 3735 | 0.032 | 0.0299 | No |
| 29 | CFH | CFH Entrez, Source | complement factor H | 3841 | 0.030 | 0.0264 | No |
| 30 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 3897 | 0.030 | 0.0267 | No |
| 31 | ELOVL6 | ELOVL6 Entrez, Source | ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4158 | 0.026 | 0.0109 | No |
| 32 | RP11-54H7.1 | RP11-54H7.1 Entrez, Source | - | 4275 | 0.025 | 0.0059 | No |
| 33 | TCIRG1 | TCIRG1 Entrez, Source | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 4289 | 0.025 | 0.0086 | No |
| 34 | SC5DL | SC5DL Entrez, Source | sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like | 4474 | 0.022 | -0.0020 | No |
| 35 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 4604 | 0.021 | -0.0087 | No |
| 36 | DLC1 | DLC1 Entrez, Source | deleted in liver cancer 1 | 4824 | 0.018 | -0.0226 | No |
| 37 | PRKCBP1 | PRKCBP1 Entrez, Source | protein kinase C binding protein 1 | 4831 | 0.018 | -0.0203 | No |
| 38 | TGIF | TGIF Entrez, Source | TGFB-induced factor (TALE family homeobox) | 5050 | 0.015 | -0.0345 | No |
| 39 | POU4F1 | POU4F1 Entrez, Source | POU domain, class 4, transcription factor 1 | 5094 | 0.015 | -0.0356 | No |
| 40 | STAT4 | STAT4 Entrez, Source | signal transducer and activator of transcription 4 | 5129 | 0.015 | -0.0360 | No |
| 41 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 5161 | 0.014 | -0.0362 | No |
| 42 | SLC7A1 | SLC7A1 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 5188 | 0.014 | -0.0361 | No |
| 43 | CYB5B | CYB5B Entrez, Source | cytochrome b5 type B (outer mitochondrial membrane) | 5195 | 0.014 | -0.0345 | No |
| 44 | MORF4L2 | MORF4L2 Entrez, Source | mortality factor 4 like 2 | 5348 | 0.012 | -0.0442 | No |
| 45 | SNTA1 | SNTA1 Entrez, Source | syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) | 5407 | 0.011 | -0.0469 | No |
| 46 | SERPINE2 | SERPINE2 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 5843 | 0.006 | -0.0789 | No |
| 47 | TRPC6 | TRPC6 Entrez, Source | transient receptor potential cation channel, subfamily C, member 6 | 5886 | 0.006 | -0.0812 | No |
| 48 | NUP50 | NUP50 Entrez, Source | nucleoporin 50kDa | 5937 | 0.005 | -0.0842 | No |
| 49 | SLC25A1 | SLC25A1 Entrez, Source | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 5938 | 0.005 | -0.0835 | No |
| 50 | NCAM1 | NCAM1 Entrez, Source | neural cell adhesion molecule 1 | 5996 | 0.005 | -0.0871 | No |
| 51 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 6728 | -0.003 | -0.1419 | No |
| 52 | COL11A1 | COL11A1 Entrez, Source | collagen, type XI, alpha 1 | 6865 | -0.004 | -0.1515 | No |
| 53 | PLA2G6 | PLA2G6 Entrez, Source | phospholipase A2, group VI (cytosolic, calcium-independent) | 6933 | -0.005 | -0.1558 | No |
| 54 | BAMBI | BAMBI Entrez, Source | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) | 7218 | -0.008 | -0.1761 | No |
| 55 | PTPN4 | PTPN4 Entrez, Source | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) | 7330 | -0.009 | -0.1832 | No |
| 56 | CDC42BPA | CDC42BPA Entrez, Source | CDC42 binding protein kinase alpha (DMPK-like) | 7499 | -0.010 | -0.1944 | No |
| 57 | ZBTB16 | ZBTB16 Entrez, Source | zinc finger and BTB domain containing 16 | 7722 | -0.013 | -0.2092 | No |
| 58 | UNC119 | UNC119 Entrez, Source | unc-119 homolog (C. elegans) | 7837 | -0.014 | -0.2158 | No |
| 59 | CTSW | CTSW Entrez, Source | cathepsin W (lymphopain) | 8068 | -0.016 | -0.2307 | No |
| 60 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 8248 | -0.018 | -0.2416 | No |
| 61 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 8303 | -0.019 | -0.2429 | No |
| 62 | TPST2 | TPST2 Entrez, Source | tyrosylprotein sulfotransferase 2 | 8366 | -0.019 | -0.2447 | No |
| 63 | LAPTM4B | LAPTM4B Entrez, Source | lysosomal associated protein transmembrane 4 beta | 8548 | -0.021 | -0.2552 | No |
| 64 | PCCB | PCCB Entrez, Source | propionyl Coenzyme A carboxylase, beta polypeptide | 8561 | -0.021 | -0.2529 | No |
| 65 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 8802 | -0.024 | -0.2675 | No |
| 66 | APPBP1 | APPBP1 Entrez, Source | amyloid beta precursor protein binding protein 1 | 8865 | -0.025 | -0.2686 | No |
| 67 | AIF1 | AIF1 Entrez, Source | allograft inflammatory factor 1 | 9000 | -0.026 | -0.2748 | No |
| 68 | GOSR2 | GOSR2 Entrez, Source | golgi SNAP receptor complex member 2 | 9004 | -0.026 | -0.2712 | No |
| 69 | PAFAH1B3 | PAFAH1B3 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa | 9189 | -0.028 | -0.2810 | No |
| 70 | GP9 | GP9 Entrez, Source | glycoprotein IX (platelet) | 9202 | -0.028 | -0.2777 | No |
| 71 | TJP2 | TJP2 Entrez, Source | tight junction protein 2 (zona occludens 2) | 9217 | -0.028 | -0.2746 | No |
| 72 | DEAF1 | DEAF1 Entrez, Source | deformed epidermal autoregulatory factor 1 (Drosophila) | 9574 | -0.032 | -0.2967 | No |
| 73 | CAPN2 | CAPN2 Entrez, Source | calpain 2, (m/II) large subunit | 9763 | -0.035 | -0.3058 | No |
| 74 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 9818 | -0.035 | -0.3046 | No |
| 75 | ATXN1 | ATXN1 Entrez, Source | ataxin 1 | 9911 | -0.036 | -0.3062 | No |
| 76 | CAST | CAST Entrez, Source | calpastatin | 10118 | -0.039 | -0.3161 | No |
| 77 | DDB1 | DDB1 Entrez, Source | damage-specific DNA binding protein 1, 127kDa | 10146 | -0.039 | -0.3123 | No |
| 78 | PROS1 | PROS1 Entrez, Source | protein S (alpha) | 10274 | -0.040 | -0.3160 | No |
| 79 | MAX | MAX Entrez, Source | MYC associated factor X | 10440 | -0.042 | -0.3221 | No |
| 80 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 10707 | -0.046 | -0.3353 | No |
| 81 | GIT2 | GIT2 Entrez, Source | G protein-coupled receptor kinase interactor 2 | 10815 | -0.048 | -0.3363 | No |
| 82 | TRPC1 | TRPC1 Entrez, Source | transient receptor potential cation channel, subfamily C, member 1 | 11504 | -0.060 | -0.3793 | No |
| 83 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 11713 | -0.065 | -0.3854 | Yes |
| 84 | NAP1L3 | NAP1L3 Entrez, Source | nucleosome assembly protein 1-like 3 | 11738 | -0.066 | -0.3775 | Yes |
| 85 | PKIG | PKIG Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 11742 | -0.066 | -0.3680 | Yes |
| 86 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 11871 | -0.069 | -0.3674 | Yes |
| 87 | PKIA | PKIA Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 12024 | -0.074 | -0.3680 | Yes |
| 88 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12131 | -0.077 | -0.3646 | Yes |
| 89 | IFNGR1 | IFNGR1 Entrez, Source | interferon gamma receptor 1 | 12154 | -0.078 | -0.3547 | Yes |
| 90 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 12169 | -0.078 | -0.3441 | Yes |
| 91 | AMD1 | AMD1 Entrez, Source | adenosylmethionine decarboxylase 1 | 12226 | -0.080 | -0.3365 | Yes |
| 92 | GIPC1 | GIPC1 Entrez, Source | GIPC PDZ domain containing family, member 1 | 12467 | -0.090 | -0.3413 | Yes |
| 93 | CXADR | CXADR Entrez, Source | coxsackie virus and adenovirus receptor | 12487 | -0.090 | -0.3293 | Yes |
| 94 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 12540 | -0.094 | -0.3194 | Yes |
| 95 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 12733 | -0.105 | -0.3183 | Yes |
| 96 | IL2RG | IL2RG Entrez, Source | interleukin 2 receptor, gamma (severe combined immunodeficiency) | 12775 | -0.109 | -0.3053 | Yes |
| 97 | SCRN1 | SCRN1 Entrez, Source | secernin 1 | 12790 | -0.110 | -0.2901 | Yes |
| 98 | SFXN3 | SFXN3 Entrez, Source | sideroflexin 3 | 12823 | -0.113 | -0.2758 | Yes |
| 99 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 12839 | -0.114 | -0.2600 | Yes |
| 100 | NET1 | NET1 Entrez, Source | neuroepithelial cell transforming gene 1 | 12910 | -0.122 | -0.2471 | Yes |
| 101 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12915 | -0.123 | -0.2292 | Yes |
| 102 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12937 | -0.125 | -0.2122 | Yes |
| 103 | KIF2A | KIF2A Entrez, Source | kinesin heavy chain member 2A | 12962 | -0.127 | -0.1952 | Yes |
| 104 | LCP1 | LCP1 Entrez, Source | lymphocyte cytosolic protein 1 (L-plastin) | 13041 | -0.138 | -0.1806 | Yes |
| 105 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 13167 | -0.169 | -0.1650 | Yes |
| 106 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 13185 | -0.179 | -0.1398 | Yes |
| 107 | MANBA | MANBA Entrez, Source | mannosidase, beta A, lysosomal | 13213 | -0.199 | -0.1122 | Yes |
| 108 | FGFR3 | FGFR3 Entrez, Source | fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) | 13275 | -0.244 | -0.0806 | Yes |
| 109 | SERPINH1 | SERPINH1 Entrez, Source | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 13285 | -0.265 | -0.0421 | Yes |
| 110 | AHNAK | AHNAK Entrez, Source | AHNAK nucleoprotein (desmoyokin) | 13307 | -0.312 | 0.0026 | Yes |
