Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_24h_versus_single_gel_24h.class.cls #double_gel_24h_versus_single_gel_24h_repos |
| Phenotype | class.cls#double_gel_24h_versus_single_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | ZHAN_MULTIPLE_MYELOMA_VS_NORMAL_DN |
| Enrichment Score (ES) | 0.52834237 |
| Normalized Enrichment Score (NES) | 1.6881819 |
| Nominal p-value | 0.011320755 |
| FDR q-value | 0.13476455 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LYZ | LYZ Entrez, Source | lysozyme (renal amyloidosis) | 34 | 0.230 | 0.1366 | Yes |
| 2 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 105 | 0.175 | 0.2372 | Yes |
| 3 | A2M | A2M Entrez, Source | alpha-2-macroglobulin | 167 | 0.155 | 0.3265 | Yes |
| 4 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 199 | 0.149 | 0.4143 | Yes |
| 5 | SYK | SYK Entrez, Source | spleen tyrosine kinase | 561 | 0.113 | 0.4555 | Yes |
| 6 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 716 | 0.103 | 0.5065 | Yes |
| 7 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 1122 | 0.086 | 0.5283 | Yes |
| 8 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 2427 | 0.053 | 0.4625 | No |
| 9 | ITGB2 | ITGB2 Entrez, Source | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 2695 | 0.048 | 0.4716 | No |
| 10 | APOC1 | APOC1 Entrez, Source | apolipoprotein C-I | 2829 | 0.046 | 0.4893 | No |
| 11 | CD24 | CD24 Entrez, Source | CD24 molecule | 3463 | 0.036 | 0.4633 | No |
| 12 | MSX1 | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 3576 | 0.034 | 0.4756 | No |
| 13 | GP5 | GP5 Entrez, Source | glycoprotein V (platelet) | 3840 | 0.030 | 0.4743 | No |
| 14 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 4222 | 0.026 | 0.4611 | No |
| 15 | LST1 | LST1 Entrez, Source | leukocyte specific transcript 1 | 4554 | 0.021 | 0.4491 | No |
| 16 | PYGL | PYGL Entrez, Source | phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) | 4760 | 0.019 | 0.4452 | No |
| 17 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 4868 | 0.018 | 0.4479 | No |
| 18 | HNMT | HNMT Entrez, Source | histamine N-methyltransferase | 5550 | 0.010 | 0.4026 | No |
| 19 | LCN2 | LCN2 Entrez, Source | lipocalin 2 (oncogene 24p3) | 5994 | 0.005 | 0.3721 | No |
| 20 | PF4 | PF4 Entrez, Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 6577 | -0.002 | 0.3295 | No |
| 21 | HHEX | HHEX Entrez, Source | homeobox, hematopoietically expressed | 8540 | -0.021 | 0.1949 | No |
| 22 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 8802 | -0.024 | 0.1898 | No |
| 23 | TOMM40 | TOMM40 Entrez, Source | translocase of outer mitochondrial membrane 40 homolog (yeast) | 8940 | -0.025 | 0.1949 | No |
| 24 | AIF1 | AIF1 Entrez, Source | allograft inflammatory factor 1 | 9000 | -0.026 | 0.2062 | No |
| 25 | CTSH | CTSH Entrez, Source | cathepsin H | 9659 | -0.033 | 0.1770 | No |
| 26 | RNASE6 | RNASE6 Entrez, Source | ribonuclease, RNase A family, k6 | 9735 | -0.034 | 0.1921 | No |
| 27 | CD99 | CD99 Entrez, Source | CD99 molecule | 9867 | -0.036 | 0.2039 | No |
| 28 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 9892 | -0.036 | 0.2239 | No |
| 29 | SMPDL3A | SMPDL3A Entrez, Source | sphingomyelin phosphodiesterase, acid-like 3A | 11365 | -0.058 | 0.1485 | No |
