Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | AACATTC,MIR-409-3P |
| Enrichment Score (ES) | -0.49434212 |
| Normalized Enrichment Score (NES) | -1.6982204 |
| Nominal p-value | 0.006557377 |
| FDR q-value | 0.06739616 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ACACA | ACACA Entrez, Source | acetyl-Coenzyme A carboxylase alpha | 157 | 0.190 | 0.0300 | No |
| 2 | CART1 | CART1 Entrez, Source | cartilage paired-class homeoprotein 1 | 296 | 0.150 | 0.0527 | No |
| 3 | KCNMA1 | KCNMA1 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, alpha member 1 | 309 | 0.148 | 0.0845 | No |
| 4 | BPNT1 | BPNT1 Entrez, Source | 3'(2'), 5'-bisphosphate nucleotidase 1 | 426 | 0.132 | 0.1049 | No |
| 5 | TWIST1 | TWIST1 Entrez, Source | twist homolog 1 (acrocephalosyndactyly 3; Saethre-Chotzen syndrome) (Drosophila) | 1621 | 0.077 | 0.0318 | No |
| 6 | CSNK1G1 | CSNK1G1 Entrez, Source | casein kinase 1, gamma 1 | 2899 | 0.052 | -0.0530 | No |
| 7 | LIN7C | LIN7C Entrez, Source | lin-7 homolog C (C. elegans) | 2999 | 0.050 | -0.0495 | No |
| 8 | MAP1A | MAP1A Entrez, Source | microtubule-associated protein 1A | 3328 | 0.045 | -0.0642 | No |
| 9 | GDF8 | GDF8 Entrez, Source | growth differentiation factor 8 | 3565 | 0.042 | -0.0727 | No |
| 10 | RIC8B | RIC8B Entrez, Source | resistance to inhibitors of cholinesterase 8 homolog B (C. elegans) | 3677 | 0.041 | -0.0721 | No |
| 11 | CLOCK | CLOCK Entrez, Source | clock homolog (mouse) | 3722 | 0.040 | -0.0666 | No |
| 12 | GPD2 | GPD2 Entrez, Source | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 3968 | 0.037 | -0.0769 | No |
| 13 | BET1 | BET1 Entrez, Source | BET1 homolog (S. cerevisiae) | 4110 | 0.035 | -0.0798 | No |
| 14 | ALPL | ALPL Entrez, Source | alkaline phosphatase, liver/bone/kidney | 4222 | 0.034 | -0.0808 | No |
| 15 | GPR88 | GPR88 Entrez, Source | G protein-coupled receptor 88 | 4235 | 0.033 | -0.0744 | No |
| 16 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 4345 | 0.032 | -0.0755 | No |
| 17 | ISL1 | ISL1 Entrez, Source | ISL1 transcription factor, LIM/homeodomain, (islet-1) | 4469 | 0.030 | -0.0781 | No |
| 18 | RPS6KB1 | RPS6KB1 Entrez, Source | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 4614 | 0.028 | -0.0827 | No |
| 19 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 4783 | 0.027 | -0.0895 | No |
| 20 | BRF2 | BRF2 Entrez, Source | BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like | 5227 | 0.021 | -0.1182 | No |
| 21 | IHPK2 | IHPK2 Entrez, Source | inositol hexaphosphate kinase 2 | 5529 | 0.018 | -0.1369 | No |
| 22 | MEOX2 | MEOX2 Entrez, Source | mesenchyme homeobox 2 | 5743 | 0.016 | -0.1496 | No |
| 23 | ARCN1 | ARCN1 Entrez, Source | archain 1 | 5908 | 0.014 | -0.1589 | No |
| 24 | SEMA4F | SEMA4F Entrez, Source | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F | 5918 | 0.014 | -0.1566 | No |
| 25 | MAL2 | MAL2 Entrez, Source | mal, T-cell differentiation protein 2 | 6069 | 0.012 | -0.1652 | No |
| 26 | USP33 | USP33 Entrez, Source | ubiquitin specific peptidase 33 | 6230 | 0.011 | -0.1749 | No |
| 27 | TGFBR1 | TGFBR1 Entrez, Source | transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) | 6257 | 0.010 | -0.1746 | No |
| 28 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 6511 | 0.007 | -0.1920 | No |
| 29 | NR4A2 | NR4A2 Entrez, Source | nuclear receptor subfamily 4, group A, member 2 | 6791 | 0.004 | -0.2121 | No |
| 30 | LYST | LYST Entrez, Source | lysosomal trafficking regulator | 6802 | 0.004 | -0.2119 | No |
| 31 | MATR3 | MATR3 Entrez, Source | matrin 3 | 6931 | 0.003 | -0.2210 | No |
| 32 | TGFBR3 | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 6986 | 0.002 | -0.2246 | No |
| 33 | TBC1D15 | TBC1D15 Entrez, Source | TBC1 domain family, member 15 | 7169 | 0.000 | -0.2383 | No |
| 34 | HNRPU | HNRPU Entrez, Source | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 7350 | -0.002 | -0.2514 | No |
| 35 | CSNK1A1 | CSNK1A1 Entrez, Source | casein kinase 1, alpha 1 | 7431 | -0.003 | -0.2568 | No |
| 36 | PPP2CA | PPP2CA Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 7638 | -0.005 | -0.2712 | No |
| 37 | HIVEP2 | HIVEP2 Entrez, Source | human immunodeficiency virus type I enhancer binding protein 2 | 7700 | -0.006 | -0.2745 | No |
| 38 | RNF38 | RNF38 Entrez, Source | ring finger protein 38 | 7815 | -0.007 | -0.2815 | No |
| 39 | HNRPK | HNRPK Entrez, Source | heterogeneous nuclear ribonucleoprotein K | 7921 | -0.009 | -0.2875 | No |
| 40 | PAX3 | PAX3 Entrez, Source | paired box gene 3 (Waardenburg syndrome 1) | 8060 | -0.010 | -0.2957 | No |
| 41 | JUN | JUN Entrez, Source | jun oncogene | 8081 | -0.010 | -0.2949 | No |
| 42 | TFEC | TFEC Entrez, Source | transcription factor EC | 8378 | -0.014 | -0.3142 | No |
| 43 | QKI | QKI Entrez, Source | quaking homolog, KH domain RNA binding (mouse) | 8852 | -0.020 | -0.3454 | No |
| 44 | PUM2 | PUM2 Entrez, Source | pumilio homolog 2 (Drosophila) | 8893 | -0.020 | -0.3439 | No |
| 45 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 9246 | -0.025 | -0.3650 | No |
| 46 | HMGN1 | HMGN1 Entrez, Source | high-mobility group nucleosome binding domain 1 | 9508 | -0.029 | -0.3782 | No |
| 47 | AP1G1 | AP1G1 Entrez, Source | adaptor-related protein complex 1, gamma 1 subunit | 9769 | -0.033 | -0.3906 | No |
| 48 | ATP6V1C2 | ATP6V1C2 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 | 10155 | -0.039 | -0.4109 | No |
| 49 | NIPBL | NIPBL Entrez, Source | Nipped-B homolog (Drosophila) | 10173 | -0.039 | -0.4035 | No |
| 50 | OGT | OGT Entrez, Source | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | 10387 | -0.043 | -0.4100 | No |
| 51 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 11062 | -0.057 | -0.4482 | No |
| 52 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 11325 | -0.063 | -0.4540 | No |
| 53 | LRP2 | LRP2 Entrez, Source | low density lipoprotein-related protein 2 | 11861 | -0.081 | -0.4764 | Yes |
| 54 | SOX6 | SOX6 Entrez, Source | SRY (sex determining region Y)-box 6 | 11905 | -0.084 | -0.4612 | Yes |
| 55 | GRK6 | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 11990 | -0.086 | -0.4485 | Yes |
| 56 | TLOC1 | TLOC1 Entrez, Source | translocation protein 1 | 12024 | -0.088 | -0.4316 | Yes |
| 57 | PCTK2 | PCTK2 Entrez, Source | PCTAIRE protein kinase 2 | 12079 | -0.091 | -0.4156 | Yes |
| 58 | FOXP1 | FOXP1 Entrez, Source | forkhead box P1 | 12207 | -0.097 | -0.4038 | Yes |
| 59 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 12446 | -0.114 | -0.3967 | Yes |
| 60 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 12631 | -0.128 | -0.3824 | Yes |
| 61 | WDR6 | WDR6 Entrez, Source | WD repeat domain 6 | 12683 | -0.133 | -0.3569 | Yes |
| 62 | PTPRF | PTPRF Entrez, Source | protein tyrosine phosphatase, receptor type, F | 12684 | -0.133 | -0.3276 | Yes |
| 63 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 12686 | -0.133 | -0.2983 | Yes |
| 64 | PDE4B | PDE4B Entrez, Source | phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) | 12954 | -0.177 | -0.2795 | Yes |
| 65 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 13031 | -0.199 | -0.2414 | Yes |
| 66 | BASP1 | BASP1 Entrez, Source | brain abundant, membrane attached signal protein 1 | 13161 | -0.265 | -0.1927 | Yes |
| 67 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 13212 | -0.305 | -0.1293 | Yes |
| 68 | SCHIP1 | SCHIP1 Entrez, Source | schwannomin interacting protein 1 | 13215 | -0.309 | -0.0614 | Yes |
| 69 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13226 | -0.322 | 0.0087 | Yes |
