Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | ABRAHAM_MM_VS_AL_UP |
| Enrichment Score (ES) | -0.6645227 |
| Normalized Enrichment Score (NES) | -1.7562542 |
| Nominal p-value | 0.0053859963 |
| FDR q-value | 0.049330357 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1896 | 0.070 | -0.0874 | No |
| 2 | PTEN | PTEN Entrez, Source | phosphatase and tensin homolog (mutated in multiple advanced cancers 1) | 4572 | 0.029 | -0.2654 | No |
| 3 | IL6ST | IL6ST Entrez, Source | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 5234 | 0.021 | -0.2985 | No |
| 4 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 7053 | 0.001 | -0.4338 | No |
| 5 | XRCC5 | XRCC5 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) | 7688 | -0.006 | -0.4770 | No |
| 6 | CDK9 | CDK9 Entrez, Source | cyclin-dependent kinase 9 (CDC2-related kinase) | 7702 | -0.006 | -0.4734 | No |
| 7 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 9613 | -0.031 | -0.5927 | No |
| 8 | PSEN1 | PSEN1 Entrez, Source | presenilin 1 (Alzheimer disease 3) | 10571 | -0.046 | -0.6282 | Yes |
| 9 | XRCC4 | XRCC4 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 4 | 10893 | -0.053 | -0.6104 | Yes |
| 10 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 10996 | -0.056 | -0.5743 | Yes |
| 11 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 11138 | -0.059 | -0.5388 | Yes |
| 12 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 11726 | -0.076 | -0.5231 | Yes |
| 13 | CDC37 | CDC37 Entrez, Source | CDC37 cell division cycle 37 homolog (S. cerevisiae) | 11983 | -0.086 | -0.4748 | Yes |
| 14 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 12003 | -0.087 | -0.4082 | Yes |
| 15 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12294 | -0.103 | -0.3492 | Yes |
| 16 | CDK5 | CDK5 Entrez, Source | cyclin-dependent kinase 5 | 12579 | -0.124 | -0.2735 | Yes |
| 17 | CD47 | CD47 Entrez, Source | CD47 molecule | 12956 | -0.177 | -0.1629 | Yes |
| 18 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 13126 | -0.245 | 0.0162 | Yes |
