Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | ACTIN_CYTOSKELETON |
| Enrichment Score (ES) | -0.5784343 |
| Normalized Enrichment Score (NES) | -1.9754738 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.011644031 |
| FWER p-Value | 0.306 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GYS2 | GYS2 Entrez, Source | glycogen synthase 2 (liver) | 370 | 0.139 | -0.0052 | No |
| 2 | ABLIM2 | ABLIM2 Entrez, Source | actin binding LIM protein family, member 2 | 400 | 0.135 | 0.0148 | No |
| 3 | TNNI3 | TNNI3 Entrez, Source | troponin I type 3 (cardiac) | 402 | 0.135 | 0.0368 | No |
| 4 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 1428 | 0.082 | -0.0270 | No |
| 5 | MARCKS | MARCKS Entrez, Source | myristoylated alanine-rich protein kinase C substrate | 1730 | 0.074 | -0.0376 | No |
| 6 | CORO1A | CORO1A Entrez, Source | coronin, actin binding protein, 1A | 1929 | 0.070 | -0.0412 | No |
| 7 | AVIL | AVIL Entrez, Source | advillin | 2021 | 0.067 | -0.0370 | No |
| 8 | MYOM1 | MYOM1 Entrez, Source | myomesin 1 (skelemin) 185kDa | 2024 | 0.067 | -0.0261 | No |
| 9 | MYH6 | MYH6 Entrez, Source | myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) | 2066 | 0.067 | -0.0183 | No |
| 10 | BMF | BMF Entrez, Source | Bcl2 modifying factor | 2145 | 0.065 | -0.0136 | No |
| 11 | LSP1 | LSP1 Entrez, Source | lymphocyte-specific protein 1 | 3215 | 0.047 | -0.0864 | No |
| 12 | SNIP | SNIP Entrez, Source | - | 3485 | 0.043 | -0.0996 | No |
| 13 | FLNB | FLNB Entrez, Source | filamin B, beta (actin binding protein 278) | 4024 | 0.036 | -0.1342 | No |
| 14 | AMPH | AMPH Entrez, Source | amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen) | 4075 | 0.035 | -0.1322 | No |
| 15 | MYH7 | MYH7 Entrez, Source | myosin, heavy chain 7, cardiac muscle, beta | 4454 | 0.031 | -0.1557 | No |
| 16 | SYNPO | SYNPO Entrez, Source | synaptopodin | 4486 | 0.030 | -0.1531 | No |
| 17 | SMTN | SMTN Entrez, Source | smoothelin | 4596 | 0.029 | -0.1566 | No |
| 18 | ESPN | ESPN Entrez, Source | espin | 4739 | 0.027 | -0.1628 | No |
| 19 | MYL3 | MYL3 Entrez, Source | myosin, light chain 3, alkali; ventricular, skeletal, slow | 5248 | 0.021 | -0.1977 | No |
| 20 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 5334 | 0.020 | -0.2008 | No |
| 21 | ACTL7B | ACTL7B Entrez, Source | actin-like 7B | 5877 | 0.014 | -0.2393 | No |
| 22 | DYNLL2 | DYNLL2 Entrez, Source | dynein, light chain, LC8-type 2 | 5886 | 0.014 | -0.2376 | No |
| 23 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 6086 | 0.012 | -0.2506 | No |
| 24 | HAP1 | HAP1 Entrez, Source | huntingtin-associated protein 1 (neuroan 1) | 7354 | -0.002 | -0.3457 | No |
| 25 | SEPT7 | SEPT7 Entrez, Source | septin 7 | 7371 | -0.002 | -0.3466 | No |
| 26 | ARPC1A | ARPC1A Entrez, Source | actin related protein 2/3 complex, subunit 1A, 41kDa | 8847 | -0.020 | -0.4544 | No |
| 27 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 8983 | -0.022 | -0.4610 | No |
| 28 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 9801 | -0.033 | -0.5171 | No |
| 29 | CLIC5 | CLIC5 Entrez, Source | chloride intracellular channel 5 | 9815 | -0.034 | -0.5126 | No |
| 30 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 10094 | -0.038 | -0.5272 | No |
| 31 | ACTR2 | ACTR2 Entrez, Source | ARP2 actin-related protein 2 homolog (yeast) | 10252 | -0.041 | -0.5324 | No |
| 32 | ABRA | ABRA Entrez, Source | actin-binding Rho activating protein | 10602 | -0.047 | -0.5510 | No |
| 33 | CAPZA2 | CAPZA2 Entrez, Source | capping protein (actin filament) muscle Z-line, alpha 2 | 10967 | -0.055 | -0.5694 | Yes |
| 34 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 11062 | -0.057 | -0.5672 | Yes |
| 35 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 11151 | -0.059 | -0.5641 | Yes |
| 36 | ACTR1B | ACTR1B Entrez, Source | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) | 11168 | -0.060 | -0.5556 | Yes |
| 37 | DCTN2 | DCTN2 Entrez, Source | dynactin 2 (p50) | 11312 | -0.063 | -0.5561 | Yes |
| 38 | SEPT9 | SEPT9 Entrez, Source | septin 9 | 11321 | -0.063 | -0.5464 | Yes |
| 39 | SPTBN4 | SPTBN4 Entrez, Source | spectrin, beta, non-erythrocytic 4 | 11326 | -0.063 | -0.5364 | Yes |
| 40 | ACTR3 | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 11757 | -0.077 | -0.5561 | Yes |
| 41 | CASK | CASK Entrez, Source | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 11862 | -0.081 | -0.5506 | Yes |
| 42 | WASL | WASL Entrez, Source | Wiskott-Aldrich syndrome-like | 11892 | -0.083 | -0.5393 | Yes |
| 43 | WASF1 | WASF1 Entrez, Source | WAS protein family, member 1 | 11932 | -0.084 | -0.5284 | Yes |
| 44 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 11935 | -0.084 | -0.5148 | Yes |
| 45 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 12047 | -0.089 | -0.5085 | Yes |
| 46 | SLC9A3R1 | SLC9A3R1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 12048 | -0.089 | -0.4939 | Yes |
| 47 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 12120 | -0.093 | -0.4841 | Yes |
| 48 | GSN | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 12230 | -0.098 | -0.4762 | Yes |
| 49 | CAPZB | CAPZB Entrez, Source | capping protein (actin filament) muscle Z-line, beta | 12275 | -0.102 | -0.4630 | Yes |
| 50 | BIN1 | BIN1 Entrez, Source | bridging integrator 1 | 12408 | -0.112 | -0.4547 | Yes |
| 51 | MYO9B | MYO9B Entrez, Source | myosin IXB | 12453 | -0.114 | -0.4393 | Yes |
| 52 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 12486 | -0.117 | -0.4226 | Yes |
| 53 | KALRN | KALRN Entrez, Source | kalirin, RhoGEF kinase | 12586 | -0.124 | -0.4098 | Yes |
| 54 | ARPC1B | ARPC1B Entrez, Source | actin related protein 2/3 complex, subunit 1B, 41kDa | 12732 | -0.139 | -0.3980 | Yes |
| 55 | ACTC1 | ACTC1 Entrez, Source | actin, alpha, cardiac muscle 1 | 12741 | -0.140 | -0.3757 | Yes |
| 56 | SORBS2 | SORBS2 Entrez, Source | sorbin and SH3 domain containing 2 | 12750 | -0.141 | -0.3533 | Yes |
| 57 | DAG1 | DAG1 Entrez, Source | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 12762 | -0.143 | -0.3308 | Yes |
| 58 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12980 | -0.185 | -0.3169 | Yes |
| 59 | MYO1C | MYO1C Entrez, Source | myosin IC | 12992 | -0.186 | -0.2873 | Yes |
| 60 | TPM4 | TPM4 Entrez, Source | tropomyosin 4 | 13032 | -0.200 | -0.2576 | Yes |
| 61 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 13042 | -0.204 | -0.2248 | Yes |
| 62 | PDLIM5 | PDLIM5 Entrez, Source | PDZ and LIM domain 5 | 13230 | -0.326 | -0.1857 | Yes |
| 63 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -1.187 | 0.0000 | Yes |
