Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | ADIPOGENESIS_HMSC_CLASS3_UP |
| Enrichment Score (ES) | 0.51412034 |
| Normalized Enrichment Score (NES) | 1.7667546 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.038117066 |
| FWER p-Value | 0.959 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NFE2 | NFE2 Entrez, Source | nuclear factor (erythroid-derived 2), 45kDa | 1 | 0.636 | 0.1471 | Yes |
| 2 | HMGCS1 | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 36 | 0.306 | 0.2153 | Yes |
| 3 | FASN | FASN Entrez, Source | fatty acid synthase | 60 | 0.267 | 0.2755 | Yes |
| 4 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 71 | 0.251 | 0.3329 | Yes |
| 5 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 98 | 0.228 | 0.3837 | Yes |
| 6 | LPIN1 | LPIN1 Entrez, Source | lipin 1 | 104 | 0.220 | 0.4343 | Yes |
| 7 | ACACA | ACACA Entrez, Source | acetyl-Coenzyme A carboxylase alpha | 157 | 0.190 | 0.4744 | Yes |
| 8 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 329 | 0.145 | 0.4951 | Yes |
| 9 | INSIG1 | INSIG1 Entrez, Source | insulin induced gene 1 | 473 | 0.128 | 0.5140 | Yes |
| 10 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 801 | 0.107 | 0.5141 | Yes |
| 11 | ITGAM | ITGAM Entrez, Source | integrin, alpha M (complement component 3 receptor 3 subunit) | 1415 | 0.082 | 0.4870 | No |
| 12 | LEPREL1 | LEPREL1 Entrez, Source | leprecan-like 1 | 1442 | 0.081 | 0.5039 | No |
| 13 | ACSL5 | ACSL5 Entrez, Source | acyl-CoA synthetase long-chain family member 5 | 1561 | 0.078 | 0.5131 | No |
| 14 | MGP | MGP Entrez, Source | matrix Gla protein | 2580 | 0.057 | 0.4498 | No |
| 15 | STOM | STOM Entrez, Source | stomatin | 3024 | 0.050 | 0.4280 | No |
| 16 | PHKG1 | PHKG1 Entrez, Source | phosphorylase kinase, gamma 1 (muscle) | 3838 | 0.039 | 0.3759 | No |
| 17 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 3852 | 0.039 | 0.3838 | No |
| 18 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 5142 | 0.022 | 0.2920 | No |
| 19 | ADFP | ADFP Entrez, Source | adipose differentiation-related protein | 5942 | 0.013 | 0.2351 | No |
| 20 | NID1 | NID1 Entrez, Source | nidogen 1 | 6040 | 0.012 | 0.2306 | No |
| 21 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 6138 | 0.012 | 0.2260 | No |
| 22 | LIPE | LIPE Entrez, Source | lipase, hormone-sensitive | 6156 | 0.011 | 0.2274 | No |
| 23 | NAB1 | NAB1 Entrez, Source | NGFI-A binding protein 1 (EGR1 binding protein 1) | 6210 | 0.011 | 0.2259 | No |
| 24 | ACACB | ACACB Entrez, Source | acetyl-Coenzyme A carboxylase beta | 6337 | 0.009 | 0.2185 | No |
| 25 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 6608 | 0.006 | 0.1997 | No |
| 26 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 6633 | 0.006 | 0.1993 | No |
| 27 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 7146 | 0.000 | 0.1609 | No |
| 28 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 7160 | 0.000 | 0.1600 | No |
| 29 | CYBRD1 | CYBRD1 Entrez, Source | cytochrome b reductase 1 | 7524 | -0.004 | 0.1337 | No |
| 30 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 8017 | -0.010 | 0.0989 | No |
| 31 | PPP1CC | PPP1CC Entrez, Source | protein phosphatase 1, catalytic subunit, gamma isoform | 8913 | -0.021 | 0.0364 | No |
| 32 | PPP2R1B | PPP2R1B Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform | 9775 | -0.033 | -0.0206 | No |
| 33 | SLC27A4 | SLC27A4 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 4 | 9907 | -0.035 | -0.0224 | No |
| 34 | NPTXR | NPTXR Entrez, Source | neuronal pentraxin receptor | 10019 | -0.037 | -0.0222 | No |
| 35 | CCNG1 | CCNG1 Entrez, Source | cyclin G1 | 10280 | -0.041 | -0.0322 | No |
| 36 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 10699 | -0.049 | -0.0523 | No |
| 37 | GM2A | GM2A Entrez, Source | GM2 ganglioside activator | 11243 | -0.061 | -0.0790 | No |
| 38 | TMEM23 | TMEM23 Entrez, Source | transmembrane protein 23 | 11708 | -0.076 | -0.0963 | No |
| 39 | CDH13 | CDH13 Entrez, Source | cadherin 13, H-cadherin (heart) | 11996 | -0.087 | -0.0978 | No |
| 40 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 12385 | -0.110 | -0.1016 | No |
| 41 | GAS6 | GAS6 Entrez, Source | growth arrest-specific 6 | 12538 | -0.120 | -0.0851 | No |
| 42 | STX3 | STX3 Entrez, Source | syntaxin 3 | 12578 | -0.124 | -0.0594 | No |
| 43 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 13060 | -0.212 | -0.0464 | No |
| 44 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 13200 | -0.292 | 0.0107 | No |
