Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | ANDROGEN_GENES |
| Enrichment Score (ES) | 0.47934517 |
| Normalized Enrichment Score (NES) | 1.5337512 |
| Nominal p-value | 0.0456621 |
| FDR q-value | 0.1267353 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NR1I3 | NR1I3 Entrez, Source | nuclear receptor subfamily 1, group I, member 3 | 153 | 0.191 | 0.0754 | Yes |
| 2 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 219 | 0.169 | 0.1473 | Yes |
| 3 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 318 | 0.147 | 0.2068 | Yes |
| 4 | TMPRSS2 | TMPRSS2 Entrez, Source | transmembrane protease, serine 2 | 572 | 0.120 | 0.2424 | Yes |
| 5 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 670 | 0.114 | 0.2868 | Yes |
| 6 | AKR1B10 | AKR1B10 Entrez, Source | aldo-keto reductase family 1, member B10 (aldose reductase) | 1081 | 0.094 | 0.2988 | Yes |
| 7 | HSD17B3 | HSD17B3 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 3 | 1112 | 0.093 | 0.3388 | Yes |
| 8 | SULT2A1 | SULT2A1 Entrez, Source | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 1153 | 0.091 | 0.3773 | Yes |
| 9 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 1342 | 0.085 | 0.4016 | Yes |
| 10 | RDH11 | RDH11 Entrez, Source | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 1395 | 0.083 | 0.4354 | Yes |
| 11 | FGF8 | FGF8 Entrez, Source | fibroblast growth factor 8 (androgen-induced) | 1623 | 0.077 | 0.4531 | Yes |
| 12 | RWDD1 | RWDD1 Entrez, Source | RWD domain containing 1 | 1914 | 0.070 | 0.4631 | Yes |
| 13 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 2098 | 0.066 | 0.4793 | Yes |
| 14 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 2646 | 0.056 | 0.4638 | No |
| 15 | AR | AR Entrez, Source | androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) | 2931 | 0.051 | 0.4658 | No |
| 16 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 4947 | 0.025 | 0.3256 | No |
| 17 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 5960 | 0.013 | 0.2555 | No |
| 18 | SHBG | SHBG Entrez, Source | sex hormone-binding globulin | 6232 | 0.011 | 0.2400 | No |
| 19 | RNF14 | RNF14 Entrez, Source | ring finger protein 14 | 6277 | 0.010 | 0.2412 | No |
| 20 | RAN | RAN Entrez, Source | RAN, member RAS oncogene family | 6446 | 0.008 | 0.2323 | No |
| 21 | CRSP6 | CRSP6 Entrez, Source | cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa | 6563 | 0.007 | 0.2266 | No |
| 22 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 7121 | 0.001 | 0.1851 | No |
| 23 | CRISP1 | CRISP1 Entrez, Source | cysteine-rich secretory protein 1 | 8585 | -0.017 | 0.0828 | No |
| 24 | STS | STS Entrez, Source | steroid sulfatase (microsomal), arylsulfatase C, isozyme S | 9956 | -0.036 | -0.0039 | No |
| 25 | HSD17B8 | HSD17B8 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 8 | 10547 | -0.046 | -0.0272 | No |
| 26 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 10661 | -0.048 | -0.0138 | No |
| 27 | CYP11B1 | CYP11B1 Entrez, Source | cytochrome P450, family 11, subfamily B, polypeptide 1 | 10762 | -0.051 | 0.0018 | No |
| 28 | PPAP2A | PPAP2A Entrez, Source | phosphatidic acid phosphatase type 2A | 11084 | -0.058 | 0.0039 | No |
| 29 | SRD5A1 | SRD5A1 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 12386 | -0.110 | -0.0439 | No |
| 30 | ARSE | ARSE Entrez, Source | arylsulfatase E (chondrodysplasia punctata 1) | 12562 | -0.122 | -0.0015 | No |
| 31 | HSD17B2 | HSD17B2 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 2 | 12678 | -0.132 | 0.0499 | No |
