Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | ANTI_APOPTOSIS |
| Enrichment Score (ES) | -0.47832656 |
| Normalized Enrichment Score (NES) | -1.7069267 |
| Nominal p-value | 0.00309119 |
| FDR q-value | 0.06417876 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DHCR24 | DHCR24 Entrez, Source | 24-dehydrocholesterol reductase | 167 | 0.185 | 0.0189 | No |
| 2 | CD40LG | CD40LG Entrez, Source | CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome) | 317 | 0.148 | 0.0329 | No |
| 3 | SNCA | SNCA Entrez, Source | synuclein, alpha (non A4 component of amyloid precursor) | 827 | 0.106 | 0.0126 | No |
| 4 | BRAF | BRAF Entrez, Source | v-raf murine sarcoma viral oncogene homolog B1 | 842 | 0.105 | 0.0295 | No |
| 5 | GCLC | GCLC Entrez, Source | glutamate-cysteine ligase, catalytic subunit | 1237 | 0.088 | 0.0149 | No |
| 6 | BCL2L10 | BCL2L10 Entrez, Source | BCL2-like 10 (apoptosis facilitator) | 1593 | 0.077 | 0.0013 | No |
| 7 | RTKN | RTKN Entrez, Source | rhotekin | 2071 | 0.066 | -0.0233 | No |
| 8 | SOCS3 | SOCS3 Entrez, Source | suppressor of cytokine signaling 3 | 2355 | 0.061 | -0.0343 | No |
| 9 | IL3 | IL3 Entrez, Source | interleukin 3 (colony-stimulating factor, multiple) | 2935 | 0.051 | -0.0692 | No |
| 10 | CIAPIN1 | CIAPIN1 Entrez, Source | cytokine induced apoptosis inhibitor 1 | 2974 | 0.050 | -0.0634 | No |
| 11 | HIPK3 | HIPK3 Entrez, Source | homeodomain interacting protein kinase 3 | 3217 | 0.047 | -0.0737 | No |
| 12 | NOTCH2 | NOTCH2 Entrez, Source | Notch homolog 2 (Drosophila) | 3652 | 0.041 | -0.0994 | No |
| 13 | CRYAA | CRYAA Entrez, Source | crystallin, alpha A | 3740 | 0.040 | -0.0991 | No |
| 14 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 4151 | 0.034 | -0.1241 | No |
| 15 | IL2RB | IL2RB Entrez, Source | interleukin 2 receptor, beta | 4191 | 0.034 | -0.1213 | No |
| 16 | AATF | AATF Entrez, Source | apoptosis antagonizing transcription factor | 4295 | 0.033 | -0.1235 | No |
| 17 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 4328 | 0.032 | -0.1204 | No |
| 18 | BCL2A1 | BCL2A1 Entrez, Source | BCL2-related protein A1 | 4610 | 0.029 | -0.1367 | No |
| 19 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 4743 | 0.027 | -0.1421 | No |
| 20 | FAS | FAS Entrez, Source | Fas (TNF receptor superfamily, member 6) | 4836 | 0.026 | -0.1446 | No |
| 21 | PROK2 | PROK2 Entrez, Source | prokineticin 2 | 4883 | 0.025 | -0.1437 | No |
| 22 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 4979 | 0.024 | -0.1468 | No |
| 23 | BNIP1 | BNIP1 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 1 | 5150 | 0.022 | -0.1558 | No |
| 24 | SON | SON Entrez, Source | SON DNA binding protein | 5446 | 0.019 | -0.1748 | No |
| 25 | HMGB1 | HMGB1 Entrez, Source | high-mobility group box 1 | 6219 | 0.011 | -0.2312 | No |
| 26 | PRKCZ | PRKCZ Entrez, Source | protein kinase C, zeta | 6220 | 0.011 | -0.2294 | No |
| 27 | TPT1 | TPT1 Entrez, Source | tumor protein, translationally-controlled 1 | 6276 | 0.010 | -0.2318 | No |
| 28 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 6400 | 0.009 | -0.2396 | No |
| 29 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 6778 | 0.004 | -0.2673 | No |
| 30 | TAX1BP1 | TAX1BP1 Entrez, Source | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 6983 | 0.002 | -0.2823 | No |
| 31 | IL1A | IL1A Entrez, Source | interleukin 1, alpha | 7065 | 0.001 | -0.2882 | No |
| 32 | BCL2L2 | BCL2L2 Entrez, Source | BCL2-like 2 | 7256 | -0.001 | -0.3024 | No |
| 33 | BECN1 | BECN1 Entrez, Source | beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) | 7449 | -0.003 | -0.3164 | No |
| 34 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 7586 | -0.005 | -0.3258 | No |
| 35 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 7619 | -0.005 | -0.3274 | No |
| 36 | SFRP1 | SFRP1 Entrez, Source | secreted frizzled-related protein 1 | 7830 | -0.007 | -0.3419 | No |
| 37 | OPA1 | OPA1 Entrez, Source | optic atrophy 1 (autosomal dominant) | 8024 | -0.010 | -0.3548 | No |
| 38 | ARHGDIA | ARHGDIA Entrez, Source | Rho GDP dissociation inhibitor (GDI) alpha | 8158 | -0.011 | -0.3629 | No |
| 39 | IL2 | IL2 Entrez, Source | interleukin 2 | 8295 | -0.013 | -0.3710 | No |
| 40 | CFLAR | CFLAR Entrez, Source | CASP8 and FADD-like apoptosis regulator | 8465 | -0.015 | -0.3811 | No |
| 41 | GDNF | GDNF Entrez, Source | glial cell derived neurotrophic factor | 8466 | -0.015 | -0.3785 | No |
| 42 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 8690 | -0.018 | -0.3923 | No |
| 43 | DAD1 | DAD1 Entrez, Source | defender against cell death 1 | 8855 | -0.020 | -0.4013 | No |
| 44 | GLO1 | GLO1 Entrez, Source | glyoxalase I | 9022 | -0.022 | -0.4100 | No |
| 45 | MCL1 | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 9085 | -0.023 | -0.4107 | No |
| 46 | PRDX2 | PRDX2 Entrez, Source | peroxiredoxin 2 | 9329 | -0.026 | -0.4246 | No |
| 47 | HDAC3 | HDAC3 Entrez, Source | histone deacetylase 3 | 9948 | -0.036 | -0.4651 | No |
| 48 | SH3GLB1 | SH3GLB1 Entrez, Source | SH3-domain GRB2-like endophilin B1 | 9998 | -0.037 | -0.4625 | No |
| 49 | SPHK1 | SPHK1 Entrez, Source | sphingosine kinase 1 | 10209 | -0.040 | -0.4715 | Yes |
| 50 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10281 | -0.041 | -0.4698 | Yes |
| 51 | YWHAZ | YWHAZ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 10313 | -0.042 | -0.4650 | Yes |
| 52 | IER3 | IER3 Entrez, Source | immediate early response 3 | 10439 | -0.044 | -0.4670 | Yes |
| 53 | PSEN1 | PSEN1 Entrez, Source | presenilin 1 (Alzheimer disease 3) | 10571 | -0.046 | -0.4689 | Yes |
| 54 | BCL2L1 | BCL2L1 Entrez, Source | BCL2-like 1 | 10657 | -0.048 | -0.4671 | Yes |
| 55 | BAG4 | BAG4 Entrez, Source | BCL2-associated athanogene 4 | 10691 | -0.049 | -0.4612 | Yes |
| 56 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 10706 | -0.050 | -0.4538 | Yes |
| 57 | CD28 | CD28 Entrez, Source | CD28 molecule | 10719 | -0.050 | -0.4462 | Yes |
| 58 | PIK3R2 | PIK3R2 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta) | 10802 | -0.052 | -0.4436 | Yes |
| 59 | SERPINB2 | SERPINB2 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 10863 | -0.053 | -0.4391 | Yes |
| 60 | BFAR | BFAR Entrez, Source | bifunctional apoptosis regulator | 11056 | -0.057 | -0.4438 | Yes |
| 61 | TXNDC1 | TXNDC1 Entrez, Source | thioredoxin domain containing 1 | 11099 | -0.058 | -0.4371 | Yes |
| 62 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 11138 | -0.059 | -0.4299 | Yes |
| 63 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 11253 | -0.061 | -0.4280 | Yes |
| 64 | BIRC4 | BIRC4 Entrez, Source | baculoviral IAP repeat-containing 4 | 11256 | -0.061 | -0.4177 | Yes |
| 65 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 11510 | -0.069 | -0.4250 | Yes |
| 66 | BRE | BRE Entrez, Source | brain and reproductive organ-expressed (TNFRSF1A modulator) | 11655 | -0.074 | -0.4233 | Yes |
| 67 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 11809 | -0.080 | -0.4212 | Yes |
| 68 | CDH13 | CDH13 Entrez, Source | cadherin 13, H-cadherin (heart) | 11996 | -0.087 | -0.4204 | Yes |
| 69 | NOL3 | NOL3 Entrez, Source | nucleolar protein 3 (apoptosis repressor with CARD domain) | 12185 | -0.096 | -0.4182 | Yes |
| 70 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 12205 | -0.097 | -0.4030 | Yes |
| 71 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 12446 | -0.114 | -0.4017 | Yes |
| 72 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 12722 | -0.137 | -0.3990 | Yes |
| 73 | BNIP3L | BNIP3L Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 12870 | -0.160 | -0.3828 | Yes |
| 74 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 12886 | -0.162 | -0.3562 | Yes |
| 75 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 12970 | -0.181 | -0.3316 | Yes |
| 76 | RTN4 | RTN4 Entrez, Source | reticulon 4 | 13167 | -0.269 | -0.3005 | Yes |
| 77 | CRYAB | CRYAB Entrez, Source | crystallin, alpha B | 13206 | -0.298 | -0.2526 | Yes |
| 78 | PEA15 | PEA15 Entrez, Source | phosphoprotein enriched in astrocytes 15 | 13282 | -0.412 | -0.1878 | Yes |
| 79 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13312 | -0.498 | -0.1049 | Yes |
| 80 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13326 | -0.627 | 0.0012 | Yes |
