Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | APOPTOSIS_GENMAPP |
| Enrichment Score (ES) | -0.5586998 |
| Normalized Enrichment Score (NES) | -1.6862124 |
| Nominal p-value | 0.006802721 |
| FDR q-value | 0.07281225 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FASLG | FASLG Entrez, Source | Fas ligand (TNF superfamily, member 6) | 1534 | 0.079 | -0.0759 | No |
| 2 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1896 | 0.070 | -0.0680 | No |
| 3 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 2994 | 0.050 | -0.1254 | No |
| 4 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 4328 | 0.032 | -0.2094 | No |
| 5 | GZMB | GZMB Entrez, Source | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 4688 | 0.028 | -0.2225 | No |
| 6 | FAS | FAS Entrez, Source | Fas (TNF receptor superfamily, member 6) | 4836 | 0.026 | -0.2206 | No |
| 7 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 5394 | 0.019 | -0.2528 | No |
| 8 | PRF1 | PRF1 Entrez, Source | perforin 1 (pore forming protein) | 6087 | 0.012 | -0.2988 | No |
| 9 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 6778 | 0.004 | -0.3484 | No |
| 10 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 6937 | 0.003 | -0.3590 | No |
| 11 | MAPK10 | MAPK10 Entrez, Source | mitogen-activated protein kinase 10 | 6962 | 0.002 | -0.3596 | No |
| 12 | JUN | JUN Entrez, Source | jun oncogene | 8081 | -0.010 | -0.4384 | No |
| 13 | MCL1 | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 9085 | -0.023 | -0.5023 | No |
| 14 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 9613 | -0.031 | -0.5265 | No |
| 15 | BIRC2 | BIRC2 Entrez, Source | baculoviral IAP repeat-containing 2 | 9946 | -0.036 | -0.5336 | No |
| 16 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10281 | -0.041 | -0.5382 | Yes |
| 17 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 10315 | -0.042 | -0.5198 | Yes |
| 18 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 10388 | -0.043 | -0.5035 | Yes |
| 19 | FADD | FADD Entrez, Source | Fas (TNFRSF6)-associated via death domain | 10437 | -0.044 | -0.4851 | Yes |
| 20 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 10643 | -0.048 | -0.4765 | Yes |
| 21 | BCL2L1 | BCL2L1 Entrez, Source | BCL2-like 1 | 10657 | -0.048 | -0.4534 | Yes |
| 22 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 10758 | -0.051 | -0.4355 | Yes |
| 23 | CASP6 | CASP6 Entrez, Source | caspase 6, apoptosis-related cysteine peptidase | 10778 | -0.051 | -0.4113 | Yes |
| 24 | TRADD | TRADD Entrez, Source | TNFRSF1A-associated via death domain | 11038 | -0.057 | -0.4024 | Yes |
| 25 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 11138 | -0.059 | -0.3804 | Yes |
| 26 | BIRC4 | BIRC4 Entrez, Source | baculoviral IAP repeat-containing 4 | 11256 | -0.061 | -0.3584 | Yes |
| 27 | BID | BID Entrez, Source | BH3 interacting domain death agonist | 11376 | -0.064 | -0.3351 | Yes |
| 28 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 11387 | -0.065 | -0.3034 | Yes |
| 29 | CASP7 | CASP7 Entrez, Source | caspase 7, apoptosis-related cysteine peptidase | 11446 | -0.066 | -0.2746 | Yes |
| 30 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 11510 | -0.069 | -0.2450 | Yes |
| 31 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 12003 | -0.087 | -0.2384 | Yes |
| 32 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 12722 | -0.137 | -0.2237 | Yes |
| 33 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12946 | -0.175 | -0.1530 | Yes |
| 34 | APAF1 | APAF1 Entrez, Source | apoptotic peptidase activating factor | 13256 | -0.365 | 0.0065 | Yes |
