Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | AROMATIC_COMPOUND_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.6574217 |
| Normalized Enrichment Score (NES) | 1.8422221 |
| Nominal p-value | 0.0020920502 |
| FDR q-value | 0.023423616 |
| FWER p-Value | 0.774 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FTCD | FTCD Entrez, Source | formiminotransferase cyclodeaminase | 27 | 0.336 | 0.2235 | Yes |
| 2 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 314 | 0.148 | 0.3014 | Yes |
| 3 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 457 | 0.129 | 0.3774 | Yes |
| 4 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 489 | 0.126 | 0.4597 | Yes |
| 5 | ALDH1L1 | ALDH1L1 Entrez, Source | aldehyde dehydrogenase 1 family, member L1 | 502 | 0.125 | 0.5426 | Yes |
| 6 | PTS | PTS Entrez, Source | 6-pyruvoyltetrahydropterin synthase | 877 | 0.104 | 0.5841 | Yes |
| 7 | SULT1B1 | SULT1B1 Entrez, Source | sulfotransferase family, cytosolic, 1B, member 1 | 1416 | 0.082 | 0.5989 | Yes |
| 8 | MOCS2 | MOCS2 Entrez, Source | molybdenum cofactor synthesis 2 | 1490 | 0.080 | 0.6469 | Yes |
| 9 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 1967 | 0.069 | 0.6574 | Yes |
| 10 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 4114 | 0.035 | 0.5198 | No |
| 11 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 4751 | 0.027 | 0.4901 | No |
| 12 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 5353 | 0.020 | 0.4583 | No |
| 13 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 5619 | 0.017 | 0.4497 | No |
| 14 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 6204 | 0.011 | 0.4132 | No |
| 15 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 8248 | -0.012 | 0.2682 | No |
| 16 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 10082 | -0.038 | 0.1562 | No |
| 17 | SPR | SPR Entrez, Source | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 10749 | -0.051 | 0.1402 | No |
| 18 | HPRT1 | HPRT1 Entrez, Source | hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) | 11843 | -0.081 | 0.1125 | No |
