Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | ATGCAGT,MIR-217 |
| Enrichment Score (ES) | -0.53327906 |
| Normalized Enrichment Score (NES) | -1.7757995 |
| Nominal p-value | 0.0033783785 |
| FDR q-value | 0.046569385 |
| FWER p-Value | 0.99 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | KCNH5 | KCNH5 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 5 | 602 | 0.118 | -0.0125 | No |
| 2 | NEUROD1 | NEUROD1 Entrez, Source | neurogenic differentiation 1 | 856 | 0.105 | -0.0022 | No |
| 3 | BCL11A | BCL11A Entrez, Source | B-cell CLL/lymphoma 11A (zinc finger protein) | 1053 | 0.095 | 0.0096 | No |
| 4 | STRBP | STRBP Entrez, Source | spermatid perinuclear RNA binding protein | 1710 | 0.074 | -0.0191 | No |
| 5 | ST18 | ST18 Entrez, Source | suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein) | 1852 | 0.071 | -0.0099 | No |
| 6 | STX1A | STX1A Entrez, Source | syntaxin 1A (brain) | 2346 | 0.061 | -0.0299 | No |
| 7 | SLC31A1 | SLC31A1 Entrez, Source | solute carrier family 31 (copper transporters), member 1 | 3616 | 0.042 | -0.1138 | No |
| 8 | CUL5 | CUL5 Entrez, Source | cullin 5 | 3868 | 0.038 | -0.1219 | No |
| 9 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 4258 | 0.033 | -0.1420 | No |
| 10 | TACC1 | TACC1 Entrez, Source | transforming, acidic coiled-coil containing protein 1 | 5137 | 0.022 | -0.2018 | No |
| 11 | GRIK2 | GRIK2 Entrez, Source | glutamate receptor, ionotropic, kainate 2 | 5711 | 0.016 | -0.2405 | No |
| 12 | GATAD2B | GATAD2B Entrez, Source | GATA zinc finger domain containing 2B | 5811 | 0.015 | -0.2438 | No |
| 13 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 6138 | 0.012 | -0.2651 | No |
| 14 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 6633 | 0.006 | -0.3006 | No |
| 15 | KCNA3 | KCNA3 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 3 | 6733 | 0.005 | -0.3066 | No |
| 16 | NR4A2 | NR4A2 Entrez, Source | nuclear receptor subfamily 4, group A, member 2 | 6791 | 0.004 | -0.3097 | No |
| 17 | DYRK1A | DYRK1A Entrez, Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 6964 | 0.002 | -0.3220 | No |
| 18 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 7024 | 0.002 | -0.3260 | No |
| 19 | TBC1D15 | TBC1D15 Entrez, Source | TBC1 domain family, member 15 | 7169 | 0.000 | -0.3368 | No |
| 20 | MAMDC2 | MAMDC2 Entrez, Source | MAM domain containing 2 | 7190 | -0.000 | -0.3383 | No |
| 21 | FN1 | FN1 Entrez, Source | fibronectin 1 | 7215 | -0.000 | -0.3400 | No |
| 22 | SOX11 | SOX11 Entrez, Source | SRY (sex determining region Y)-box 11 | 7315 | -0.002 | -0.3470 | No |
| 23 | NFIA | NFIA Entrez, Source | nuclear factor I/A | 7418 | -0.003 | -0.3539 | No |
| 24 | EIF4A2 | EIF4A2 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 2 | 7450 | -0.003 | -0.3553 | No |
| 25 | ATP1B1 | ATP1B1 Entrez, Source | ATPase, Na+/K+ transporting, beta 1 polypeptide | 7708 | -0.006 | -0.3730 | No |
| 26 | POLG | POLG Entrez, Source | polymerase (DNA directed), gamma | 7953 | -0.009 | -0.3889 | No |
| 27 | CHN2 | CHN2 Entrez, Source | chimerin (chimaerin) 2 | 7974 | -0.009 | -0.3878 | No |
| 28 | FBN2 | FBN2 Entrez, Source | fibrillin 2 (congenital contractural arachnodactyly) | 8235 | -0.012 | -0.4040 | No |
| 29 | JOSD3 | JOSD3 Entrez, Source | Josephin domain containing 3 | 8353 | -0.014 | -0.4090 | No |
| 30 | APPBP2 | APPBP2 Entrez, Source | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 8474 | -0.015 | -0.4138 | No |
| 31 | ACVR2A | ACVR2A Entrez, Source | activin A receptor, type IIA | 8618 | -0.017 | -0.4198 | No |
| 32 | KRAS | KRAS Entrez, Source | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 8834 | -0.020 | -0.4305 | No |
| 33 | GDI2 | GDI2 Entrez, Source | GDP dissociation inhibitor 2 | 8938 | -0.021 | -0.4323 | No |
| 34 | YWHAG | YWHAG Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 9159 | -0.024 | -0.4422 | No |
| 35 | UBXD8 | UBXD8 Entrez, Source | UBX domain containing 8 | 9520 | -0.029 | -0.4611 | No |
| 36 | MTPN | MTPN Entrez, Source | myotrophin | 9804 | -0.033 | -0.4731 | No |
| 37 | SLC38A2 | SLC38A2 Entrez, Source | solute carrier family 38, member 2 | 9913 | -0.035 | -0.4714 | No |
| 38 | NIPBL | NIPBL Entrez, Source | Nipped-B homolog (Drosophila) | 10173 | -0.039 | -0.4799 | No |
| 39 | SEPT4 | SEPT4 Entrez, Source | septin 4 | 10191 | -0.040 | -0.4700 | No |
| 40 | DLGAP2 | DLGAP2 Entrez, Source | discs, large (Drosophila) homolog-associated protein 2 | 10230 | -0.040 | -0.4616 | No |
| 41 | OGT | OGT Entrez, Source | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | 10387 | -0.043 | -0.4613 | No |
| 42 | TACC2 | TACC2 Entrez, Source | transforming, acidic coiled-coil containing protein 2 | 10838 | -0.052 | -0.4805 | No |
| 43 | MYEF2 | MYEF2 Entrez, Source | myelin expression factor 2 | 11075 | -0.057 | -0.4822 | No |
| 44 | NDEL1 | NDEL1 Entrez, Source | nudE nuclear distribution gene E homolog like 1 (A. nidulans) | 11755 | -0.077 | -0.5117 | Yes |
| 45 | UBL3 | UBL3 Entrez, Source | ubiquitin-like 3 | 11776 | -0.078 | -0.4914 | Yes |
| 46 | CAPN3 | CAPN3 Entrez, Source | calpain 3, (p94) | 11952 | -0.085 | -0.4808 | Yes |
| 47 | FBXO11 | FBXO11 Entrez, Source | F-box protein 11 | 12316 | -0.105 | -0.4789 | Yes |
| 48 | DYNC1LI2 | DYNC1LI2 Entrez, Source | dynein, cytoplasmic 1, light intermediate chain 2 | 12591 | -0.125 | -0.4646 | Yes |
| 49 | STX6 | STX6 Entrez, Source | syntaxin 6 | 12778 | -0.145 | -0.4382 | Yes |
| 50 | ADAMTS5 | ADAMTS5 Entrez, Source | ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2) | 12892 | -0.163 | -0.4010 | Yes |
| 51 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 13083 | -0.223 | -0.3529 | Yes |
| 52 | GPM6A | GPM6A Entrez, Source | glycoprotein M6A | 13085 | -0.224 | -0.2905 | Yes |
| 53 | AKAP2 | AKAP2 Entrez, Source | A kinase (PRKA) anchor protein 2 | 13096 | -0.230 | -0.2268 | Yes |
| 54 | TMSB4X | TMSB4X Entrez, Source | thymosin, beta 4, X-linked | 13134 | -0.249 | -0.1601 | Yes |
| 55 | MSN | MSN Entrez, Source | moesin | 13327 | -0.629 | 0.0011 | Yes |
